hif2a_16565084_mcf7_lof_human_gpl2507_gds2761 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2761
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Genes

522 genes differentially expressed following the hif2a_16565084_mcf7_lof_human_gpl2507_gds2761 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
CDC123 cell division cycle 123 1.5402
IQGAP1 IQ motif containing GTPase activating protein 1 1.53804
WWC1 WW and C2 domain containing 1 1.53779
FUCA1 fucosidase, alpha-L- 1, tissue 1.53507
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa 1.52938
HIC2 hypermethylated in cancer 2 1.52624
VAMP7 vesicle-associated membrane protein 7 1.52328
SEPT2 septin 2 1.52312
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 1.52143
ARID3B AT rich interactive domain 3B (BRIGHT-like) 1.51789
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 1.50999
MSI1 musashi RNA-binding protein 1 1.50394
IDS iduronate 2-sulfatase 1.50257
TUBA1A tubulin, alpha 1a 1.49992
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase 1.49909
S100A14 S100 calcium binding protein A14 1.49786
CDC45 cell division cycle 45 1.49302
PAX4 paired box 4 1.49221
COQ5 coenzyme Q5 homolog, methyltransferase (S. cerevisiae) 1.48026
WDR19 WD repeat domain 19 1.47694
PDCD2 programmed cell death 2 1.47587
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 1.47465
ARFIP2 ADP-ribosylation factor interacting protein 2 1.47416
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) 1.46313
CCDC25 coiled-coil domain containing 25 1.46207
SGPL1 sphingosine-1-phosphate lyase 1 1.45197
MSL3 male-specific lethal 3 homolog (Drosophila) 1.44408
CNEP1R1 CTD nuclear envelope phosphatase 1 regulatory subunit 1 1.4248
TMX1 thioredoxin-related transmembrane protein 1 1.42414
MPRIP myosin phosphatase Rho interacting protein 1.4194
ASB9 ankyrin repeat and SOCS box containing 9 1.41917
LRP1 low density lipoprotein receptor-related protein 1 1.41808
RGS16 regulator of G-protein signaling 16 1.41567
CDC42SE1 CDC42 small effector 1 1.41442
RFC3 replication factor C (activator 1) 3, 38kDa 1.41165
STK40 serine/threonine kinase 40 1.40808
SQRDL sulfide quinone reductase-like (yeast) 1.40724
TWSG1 twisted gastrulation BMP signaling modulator 1 1.40446
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 1.40321
SART3 squamous cell carcinoma antigen recognized by T cells 3 1.40071
UBE2W ubiquitin-conjugating enzyme E2W (putative) 1.39693
SLC25A30 solute carrier family 25, member 30 1.39406
HIST3H3 histone cluster 3, H3 1.39273
KLC1 kinesin light chain 1 1.3869
NUP210 nucleoporin 210kDa 1.3772
POM121 POM121 transmembrane nucleoporin 1.37331
UGT1A8 UDP glucuronosyltransferase 1 family, polypeptide A8 1.36385
SPCS1 signal peptidase complex subunit 1 homolog (S. cerevisiae) 1.35747
MPZL1 myelin protein zero-like 1 1.35629
PBX3 pre-B-cell leukemia homeobox 3 1.35165
RIPPLY3 ripply transcriptional repressor 3 1.34616
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog 1.34575
ALKBH5 AlkB family member 5, RNA demethylase 1.3431
PPP1R16A protein phosphatase 1, regulatory subunit 16A 1.33966
WASF3 WAS protein family, member 3 1.33905
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c 1.33905
IRAK1 interleukin-1 receptor-associated kinase 1 1.33905
TMEM9B TMEM9 domain family, member B 1.33708
KAZALD1 Kazal-type serine peptidase inhibitor domain 1 1.33673
ATOH8 atonal homolog 8 (Drosophila) 1.33475
ZNF322 zinc finger protein 322 1.33475
RALA v-ral simian leukemia viral oncogene homolog A (ras related) 1.33216
LONP2 lon peptidase 2, peroxisomal 1.32385
SP1 Sp1 transcription factor 1.31691
ATG9A autophagy related 9A 1.31048
HOXC13 homeobox C13 1.30736
TOMM34 translocase of outer mitochondrial membrane 34 1.30683
ALG3 ALG3, alpha-1,3- mannosyltransferase 1.30386
RWDD4 RWD domain containing 4 1.29943
STRADB STE20-related kinase adaptor beta 1.29819
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 1.29549
GPN1 GPN-loop GTPase 1 1.29365
AKR1C1 aldo-keto reductase family 1, member C1 1.27916
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 1.27125
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon 1.26409
SLC39A10 solute carrier family 39 (zinc transporter), member 10 1.26409
STX2 syntaxin 2 1.25957
HIST1H2BJ histone cluster 1, H2bj 1.25392
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 1.2509
TGDS TDP-glucose 4,6-dehydratase 1.24176
RYBP RING1 and YY1 binding protein 1.2243
SECISBP2 SECIS binding protein 2 1.21741
KIAA1598 1.20453
SRXN1 sulfiredoxin 1 1.20453
SOCS5 suppressor of cytokine signaling 5 1.1869
HN1L hematological and neurological expressed 1-like 1.17705
LASP1 LIM and SH3 protein 1 1.17687
NOXO1 NADPH oxidase organizer 1 1.17094
H1F0 H1 histone family, member 0 1.16745
RHNO1 RAD9-HUS1-RAD1 interacting nuclear orphan 1 1.16188
SBF1 SET binding factor 1 1.15858
DST dystonin 1.15723
EIF1AX eukaryotic translation initiation factor 1A, X-linked 1.15095
ATF6 activating transcription factor 6 1.15049
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 1.15049
EPHA6 EPH receptor A6 1.14942
SLC44A1 solute carrier family 44 (choline transporter), member 1 1.1351
RPN1 ribophorin I 1.12383
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5 1.12179
ANKFY1 ankyrin repeat and FYVE domain containing 1 1.11178
MGST1 microsomal glutathione S-transferase 1 1.09922
CDK2AP1 cyclin-dependent kinase 2 associated protein 1 1.09912
GNG5 guanine nucleotide binding protein (G protein), gamma 5 1.09789
RRAGC Ras-related GTP binding C 1.09458
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 1.09166
DHRS11 dehydrogenase/reductase (SDR family) member 11 1.06165
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase 1.05715
RGMA repulsive guidance molecule family member a 1.05593
ANO6 anoctamin 6 1.05178
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 1.05178
KIF20A kinesin family member 20A 1.03798
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 1.03072
DIDO1 death inducer-obliterator 1 1.02809
SPRYD3 SPRY domain containing 3 1.01863
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 1.01427
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F 0.998143
PSMC4 proteasome (prosome, macropain) 26S subunit, ATPase, 4 0.994995
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.986104
CMSS1 cms1 ribosomal small subunit homolog (yeast) 0.975025
FAM222B family with sequence similarity 222, member B 0.965072
C1ORF189 chromosome 1 open reading frame 189 0.96359
CRY2 cryptochrome circadian clock 2 0.961588
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.958434
GDPD1 glycerophosphodiester phosphodiesterase domain containing 1 0.956089
ZDHHC3 zinc finger, DHHC-type containing 3 0.941619
DIRAS1 DIRAS family, GTP-binding RAS-like 1 0.913311
FAM57A family with sequence similarity 57, member A 0.912958
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2 0.906083
ZCCHC3 zinc finger, CCHC domain containing 3 0.903138
MFAP1 microfibrillar-associated protein 1 0.891102
IL13RA1 interleukin 13 receptor, alpha 1 0.890133
ENDOD1 endonuclease domain containing 1 0.877993
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae) 0.877916
S100A6 S100 calcium binding protein A6 0.876376
SMIM19 small integral membrane protein 19 0.874724
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.86825
NCAPD3 non-SMC condensin II complex, subunit D3 0.867702
MYCBP MYC binding protein 0.867702
SSR1 signal sequence receptor, alpha 0.860436
DNM1L dynamin 1-like 0.837622
TNF tumor necrosis factor 0.828774
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa 0.827086
ILF3 interleukin enhancer binding factor 3, 90kDa 0.820759
STRA13 stimulated by retinoic acid 13 0.820759
DHDH dihydrodiol dehydrogenase (dimeric) 0.820759
HOOK2 hook microtubule-tethering protein 2 0.805426
EFHD1 EF-hand domain family, member D1 0.802356
EPS8L1 EPS8-like 1 0.800637
CAPRIN2 caprin family member 2 0.774737
TOP1 topoisomerase (DNA) I 0.753161
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin) 0.752162
NDRG3 NDRG family member 3 0.748635
MB21D1 Mab-21 domain containing 1 0.743353
ADI1 acireductone dioxygenase 1 0.737746
VEZT vezatin, adherens junctions transmembrane protein 0.717003
KCTD10 potassium channel tetramerization domain containing 10 0.695829
MTSS1 metastasis suppressor 1 0.694246
DUS1L dihydrouridine synthase 1-like (S. cerevisiae) 0.664118
GFPT2 glutamine-fructose-6-phosphate transaminase 2 0.658063
UQCR10 ubiquinol-cytochrome c reductase, complex III subunit X 0.633183
EXOC4 exocyst complex component 4 0.627772
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 0.614356
VBP1 von Hippel-Lindau binding protein 1 0.611314
TPRG1L tumor protein p63 regulated 1-like 0.597372
MCCC2 methylcrotonoyl-CoA carboxylase 2 (beta) 0.597118
GIMAP4 GTPase, IMAP family member 4 0.555716
MT1X metallothionein 1X 0.546089
HIST2H3C histone cluster 2, H3c 0.539091
KIAA0195 KIAA0195 0.534154
FUBP1 far upstream element (FUSE) binding protein 1 0.534154
SGK1 serum/glucocorticoid regulated kinase 1 0.527797
EPN2 epsin 2 0.523566
UBE2V1 ubiquitin-conjugating enzyme E2 variant 1 0.491982
C17ORF58 chromosome 17 open reading frame 58 0.49109
CBFB core-binding factor, beta subunit 0.490043
IK IK cytokine, down-regulator of HLA II 0.485835
MAGED2 melanoma antigen family D2 0.484867
COTL1 coactosin-like F-actin binding protein 1 0.478926
ZNF800 zinc finger protein 800 0.47415
H2AFV H2A histone family, member V 0.466956
ALG9 ALG9, alpha-1,2-mannosyltransferase 0.464988
MIF4GD MIF4G domain containing 0.461642
A4GALT alpha 1,4-galactosyltransferase 0.461642
LMBR1L limb development membrane protein 1-like 0.454889
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.452583
SLC2A13 solute carrier family 2 (facilitated glucose transporter), member 13 0.434676
ZCCHC14 zinc finger, CCHC domain containing 14 0.43003
COMMD1 copper metabolism (Murr1) domain containing 1 0.429598
MAGEF1 melanoma antigen family F1 0.420831
MRPL42 mitochondrial ribosomal protein L42 0.415041
TRUB1 TruB pseudouridine (psi) synthase family member 1 0.41296
MEMO1 mediator of cell motility 1 0.410911
ICMT isoprenylcysteine carboxyl methyltransferase 0.407544
RAB24 RAB24, member RAS oncogene family 0.40667
N4BP2 NEDD4 binding protein 2 0.405646
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.398435
NDE1 nudE neurodevelopment protein 1 0.397419
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme 0.395093
ZKSCAN4 zinc finger with KRAB and SCAN domains 4 0.387038
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.386201
KARS lysyl-tRNA synthetase 0.378975
SMOX spermine oxidase 0.377043
LIPT1 lipoyltransferase 1 0.377043
CDC25A cell division cycle 25A 0.376005
THBD thrombomodulin 0.374631
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.372746
LEPROT leptin receptor overlapping transcript 0.370637
AURKA aurora kinase A 0.370351
BAGE4 B melanoma antigen family, member 4 0.370351
FBXW9 F-box and WD repeat domain containing 9 0.360948
NAP1L1 nucleosome assembly protein 1-like 1 0.360337
TBCA tubulin folding cofactor A 0.355536
FGL1 fibrinogen-like 1 0.355017
RPN2 ribophorin II 0.347877
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative) 0.344706
CCNY cyclin Y 0.341185
ABT1 activator of basal transcription 1 0.336557
MANEAL mannosidase, endo-alpha-like 0.33645
DNER delta/notch-like EGF repeat containing 0.336178
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.332909
SMAGP small cell adhesion glycoprotein 0.332507
BMI1 BMI1 proto-oncogene, polycomb ring finger 0.330856
CPD carboxypeptidase D 0.328288
PPTC7 PTC7 protein phosphatase homolog (S. cerevisiae) 0.326491
FBXO33 F-box protein 33 0.324711
MNS1 meiosis-specific nuclear structural 1 0.319115
HNRNPR heterogeneous nuclear ribonucleoprotein R 0.317557
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.315031
NAA35 N(alpha)-acetyltransferase 35, NatC auxiliary subunit 0.315031
BLCAP bladder cancer associated protein 0.312192
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 0.307777
ZBTB39 zinc finger and BTB domain containing 39 0.307485
RNF138 ring finger protein 138, E3 ubiquitin protein ligase 0.305034
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.304933
SRSF8 serine/arginine-rich splicing factor 8 0.30313
PPP2R2C protein phosphatase 2, regulatory subunit B, gamma 0.30135
H1FX H1 histone family, member X 0.297812
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 0.296148
SPATA2 spermatogenesis associated 2 0.291671
PKP4 plakophilin 4 0.29101
YTHDC1 YTH domain containing 1 0.29101
ZNF395 zinc finger protein 395 0.288003
RMDN1 regulator of microtubule dynamics 1 0.280621
OSTM1 osteopetrosis associated transmembrane protein 1 0.278816
TMEM26 transmembrane protein 26 0.278707
PCNX pecanex homolog (Drosophila) 0.27767
KLHL8 kelch-like family member 8 0.271495
FBXO42 F-box protein 42 0.271351
SLC22A5 solute carrier family 22 (organic cation/carnitine transporter), member 5 0.271052
DHX40 DEAH (Asp-Glu-Ala-His) box polypeptide 40 0.270806
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 0.268237
GEMIN5 gem (nuclear organelle) associated protein 5 0.263296
B3GNT1 0.263296
ADSSL1 adenylosuccinate synthase like 1 0.259296
GLRX5 glutaredoxin 5 0.258041
LIMCH1 LIM and calponin homology domains 1 0.257808
FAXC failed axon connections homolog (Drosophila) 0.257808
NKAIN1 Na+/K+ transporting ATPase interacting 1 0.253754
PROK1 prokineticin 1 0.247776
HELB helicase (DNA) B 0.244497
ZIC1 Zic family member 1 0.244123
PPP1R3C protein phosphatase 1, regulatory subunit 3C 0.242978
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.242978
MELK maternal embryonic leucine zipper kinase 0.242978
FAR1 fatty acyl CoA reductase 1 0.239078
TFG TRK-fused gene 0.238417
PITHD1 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1 0.23631
MFSD8 major facilitator superfamily domain containing 8 0.235992
IFRD2 interferon-related developmental regulator 2 0.229132
UBE2F ubiquitin-conjugating enzyme E2F (putative) 0.226207
POMGNT2 protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-) 0.216458
PPP4R1 protein phosphatase 4, regulatory subunit 1 0.213325
PRC1 protein regulator of cytokinesis 1 0.209556
CUL1 cullin 1 0.206958
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.198469
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1 0.191422
AKIP1 A kinase (PRKA) interacting protein 1 0.190747
STXBP5 syntaxin binding protein 5 (tomosyn) 0.187881
HEATR6 HEAT repeat containing 6 0.181041
PROSER1 proline and serine rich 1 0.173617
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.168913
PGRMC1 progesterone receptor membrane component 1 0.159425
ABHD12 abhydrolase domain containing 12 0.157163
FZD2 frizzled class receptor 2 0.157163
ORAI1 ORAI calcium release-activated calcium modulator 1 0.14745
MYEOV2 myeloma overexpressed 2 0.14745
PI4K2A phosphatidylinositol 4-kinase type 2 alpha 0.142832
ZNF337 zinc finger protein 337 0.136826
MGST2 microsomal glutathione S-transferase 2 0.132675
STAU2 staufen double-stranded RNA binding protein 2 0.130682
MSI2 musashi RNA-binding protein 2 0.128799
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 0.120928
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.119561
FAM46C family with sequence similarity 46, member C 0.100258
PATL1 protein associated with topoisomerase II homolog 1 (yeast) 0.093182
DPY19L1 dpy-19-like 1 (C. elegans) 0.074383
COG1 component of oligomeric golgi complex 1 0.074383
DDB1 damage-specific DNA binding protein 1, 127kDa 0.05714
TAF5L TAF5-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa 0.055994
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 0.055564
CRAMP1L Crm, cramped-like (Drosophila) 0.044972
FAM160B1 family with sequence similarity 160, member B1 0.04479
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.04243
MECOM MDS1 and EVI1 complex locus 0.039244
FBXO4 F-box protein 4 0.037245
TCFL5 transcription factor-like 5 (basic helix-loop-helix) 0.037245
ETV6 ets variant 6 0.036183
C5ORF30 chromosome 5 open reading frame 30 0.026674
SLC38A9 solute carrier family 38, member 9 0.019093
AK3 adenylate kinase 3 0.018929
MYO19 myosin XIX 0.012484
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2 0.011339
AP3B2 adaptor-related protein complex 3, beta 2 subunit 0.008831
VRK3 vaccinia related kinase 3 0.003723
TBC1D20 TBC1 domain family, member 20 0.003383
PTGES prostaglandin E synthase 0.001837

decreased expression

Symbol Name Standardized Value
ATL3 atlastin GTPase 3 -0.37134
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta -0.37134
NTHL1 nth endonuclease III-like 1 (E. coli) -0.37134
MRPL11 mitochondrial ribosomal protein L11 -0.37134
MEIS2 Meis homeobox 2 -0.370909
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated -0.369647
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -0.369353
PRKCD protein kinase C, delta -0.368723
ACOX1 acyl-CoA oxidase 1, palmitoyl -0.367795
UPK2 uroplakin 2 -0.36666
TP53BP1 tumor protein p53 binding protein 1 -0.364012
GALT galactose-1-phosphate uridylyltransferase -0.364012
SH3BP5 SH3-domain binding protein 5 (BTK-associated) -0.362163
RAD9B RAD9 homolog B (S. pombe) -0.359363
CTNND1 catenin (cadherin-associated protein), delta 1 -0.355287
HMG20A high mobility group 20A -0.355287
KDELC1 KDEL (Lys-Asp-Glu-Leu) containing 1 -0.354977
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.353812
MARCH3 membrane-associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase -0.352126
PEA15 phosphoprotein enriched in astrocytes 15 -0.351475
CAPS calcyphosine -0.351475
DPY30 dpy-30 homolog (C. elegans) -0.351475
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 -0.350367
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 -0.350163
ISG20 interferon stimulated exonuclease gene 20kDa -0.344743
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) -0.340811
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 -0.339607
RTN2 reticulon 2 -0.339158
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.33622
MED27 mediator complex subunit 27 -0.331733
PHF5A PHD finger protein 5A -0.329218
PRRG4 proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) -0.326732
ZSWIM8 zinc finger, SWIM-type containing 8 -0.322209
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 -0.321801
THOC7 THO complex 7 -0.320516
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor -0.319936
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.318863
XYLT2 xylosyltransferase II -0.316646
COPA coatomer protein complex, subunit alpha -0.313636
OTOP2 otopetrin 2 -0.312937
KIAA0586 KIAA0586 -0.312656
FAM198B family with sequence similarity 198, member B -0.310183
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 -0.30912
DPYSL4 dihydropyrimidinase-like 4 -0.309071
DCAF8L2 DDB1 and CUL4 associated factor 8-like 2 -0.307911
LARP4B La ribonucleoprotein domain family, member 4B -0.298412
LPCAT3 lysophosphatidylcholine acyltransferase 3 -0.297711
ANKRD46 ankyrin repeat domain 46 -0.29508
IGF1R insulin-like growth factor 1 receptor -0.29508
L2HGDH L-2-hydroxyglutarate dehydrogenase -0.295056
CD46 CD46 molecule, complement regulatory protein -0.294117
CASP14 caspase 14, apoptosis-related cysteine peptidase -0.293599
ATXN2L ataxin 2-like -0.291231
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 -0.28503
GRAMD4 GRAM domain containing 4 -0.28503
STOM stomatin -0.28478
GLS glutaminase -0.28478
ATRX alpha thalassemia/mental retardation syndrome X-linked -0.280791
STMN3 stathmin-like 3 -0.280565
TTI2 TELO2 interacting protein 2 -0.279092
HIST1H2AM histone cluster 1, H2am -0.27851
MOAP1 modulator of apoptosis 1 -0.270931
DMPK dystrophia myotonica-protein kinase -0.270659
STK24 serine/threonine kinase 24 -0.267292
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein -0.266363
RAB17 RAB17, member RAS oncogene family -0.263956
RNF32 ring finger protein 32 -0.26317
DSP desmoplakin -0.261986
C6ORF106 chromosome 6 open reading frame 106 -0.259387
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -0.258357
ZSCAN18 zinc finger and SCAN domain containing 18 -0.258357
CIPC CLOCK-interacting pacemaker -0.256721
SOWAHC sosondowah ankyrin repeat domain family member C -0.256125
OSBPL10 oxysterol binding protein-like 10 -0.256102
LONP1 lon peptidase 1, mitochondrial -0.255659
STK38 serine/threonine kinase 38 -0.25525
KCTD6 potassium channel tetramerization domain containing 6 -0.25525
SEPN1 selenoprotein N, 1 -0.254398
DUSP8 dual specificity phosphatase 8 -0.254398
TOR1AIP1 torsin A interacting protein 1 -0.249916
TTC5 tetratricopeptide repeat domain 5 -0.24793
FNBP1 formin binding protein 1 -0.244084
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -0.242847
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4 -0.242616
CALU calumenin -0.242581
SLPI secretory leukocyte peptidase inhibitor -0.239526
XKR8 XK, Kell blood group complex subunit-related family, member 8 -0.238697
INHBB inhibin, beta B -0.237042
COG6 component of oligomeric golgi complex 6 -0.235173
EDN1 endothelin 1 -0.234508
MCM3AP minichromosome maintenance complex component 3 associated protein -0.230533
KIAA0226 KIAA0226 -0.230533
SPATA31A7 SPATA31 subfamily A, member 7 -0.229963
MPLKIP M-phase specific PLK1 interacting protein -0.228824
HSPA13 heat shock protein 70kDa family, member 13 -0.228824
TMEM198 transmembrane protein 198 -0.228824
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1 -0.228221
G3BP1 GTPase activating protein (SH3 domain) binding protein 1 -0.227607
SHOX2 short stature homeobox 2 -0.226631
MMP25 matrix metallopeptidase 25 -0.22193
WDR92 WD repeat domain 92 -0.219008
NAAA N-acylethanolamine acid amidase -0.218343
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 -0.217285
IRX2 iroquois homeobox 2 -0.215711
FAM122B family with sequence similarity 122B -0.213792
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.212738
PDGFB platelet-derived growth factor beta polypeptide -0.209081
RIMKLA ribosomal modification protein rimK-like family member A -0.208657
CLDN12 claudin 12 -0.207965
RPRM reprimo, TP53 dependent G2 arrest mediator candidate -0.20743
CUTC cutC copper transporter -0.207263
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1 -0.204692
DIAPH2 diaphanous-related formin 2 -0.204047
FOXO1 forkhead box O1 -0.202848
NAIF1 nuclear apoptosis inducing factor 1 -0.202215
ZNF768 zinc finger protein 768 -0.201938
VTI1B vesicle transport through interaction with t-SNAREs 1B -0.201483
SLC25A16 solute carrier family 25 (mitochondrial carrier), member 16 -0.198705
ADAMTS10 ADAM metallopeptidase with thrombospondin type 1 motif, 10 -0.198705
FAM89A family with sequence similarity 89, member A -0.198649
MUC20 mucin 20, cell surface associated -0.198649
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -0.194213
COL9A2 collagen, type IX, alpha 2 -0.193696
RAD54L RAD54-like (S. cerevisiae) -0.189969
ANAPC5 anaphase promoting complex subunit 5 -0.189595
CHN1 chimerin 1 -0.188268
FILIP1L filamin A interacting protein 1-like -0.187851
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) -0.187653
ECE2 endothelin converting enzyme 2 -0.186952
ZNF32 zinc finger protein 32 -0.185965
CCDC174 coiled-coil domain containing 174 -0.18441
ACER3 alkaline ceramidase 3 -0.183545
ZNF777 zinc finger protein 777 -0.183545
ARPC5L actin related protein 2/3 complex, subunit 5-like -0.182494
THAP11 THAP domain containing 11 -0.181706
MAP3K7 mitogen-activated protein kinase kinase kinase 7 -0.181115
TMEM57 transmembrane protein 57 -0.178478
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A -0.174136
YBX2 Y box binding protein 2 -0.172921
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 -0.170908
UFD1L ubiquitin fusion degradation 1 like (yeast) -0.170908
XPOT exportin, tRNA -0.169738
RELL2 RELT-like 2 -0.168939
ACTR1B ARP1 actin-related protein 1 homolog B, centractin beta (yeast) -0.168709
BCCIP BRCA2 and CDKN1A interacting protein -0.167265
RMDN3 regulator of microtubule dynamics 3 -0.166553
C6ORF136 chromosome 6 open reading frame 136 -0.166258
FOXM1 forkhead box M1 -0.165569
SMDT1 single-pass membrane protein with aspartate-rich tail 1 -0.162002
GYG1 glycogenin 1 -0.160208
NME7 NME/NM23 family member 7 -0.159093
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.157705
GIPC1 GIPC PDZ domain containing family, member 1 -0.156941
TJP2 tight junction protein 2 -0.156798
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe) -0.151607
SUGP2 SURP and G patch domain containing 2 -0.148865
RBM28 RNA binding motif protein 28 -0.148441
SYP synaptophysin -0.148083
SHPK sedoheptulokinase -0.145717
SRSF5 serine/arginine-rich splicing factor 5 -0.145696
RBM18 RNA binding motif protein 18 -0.143323
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 -0.142814
CSNK1D casein kinase 1, delta -0.137603
UBE2R2 ubiquitin-conjugating enzyme E2R 2 -0.137333
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -0.135483
ABAT 4-aminobutyrate aminotransferase -0.133955
SLC35B1 solute carrier family 35, member B1 -0.121367
TMEM248 transmembrane protein 248 -0.112582
CDC42BPB CDC42 binding protein kinase beta (DMPK-like) -0.10961
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -0.10961
REEP4 receptor accessory protein 4 -0.109156
ZNF330 zinc finger protein 330 -0.108223
LPPR2 lipid phosphate phosphatase-related protein type 2 -0.10818
ATPIF1 ATPase inhibitory factor 1 -0.1077
LEO1 Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.102206
RBM24 RNA binding motif protein 24 -0.101316
TBC1D31 TBC1 domain family, member 31 -0.094071
TRIM8 tripartite motif containing 8 -0.094071
ETHE1 ethylmalonic encephalopathy 1 -0.082429
WFDC3 WAP four-disulfide core domain 3 -0.081779
PPP1R3D protein phosphatase 1, regulatory subunit 3D -0.08086
TMEM127 transmembrane protein 127 -0.080813
HIST1H2BK histone cluster 1, H2bk -0.080269
MT1H metallothionein 1H -0.073521
MED20 mediator complex subunit 20 -0.06916
TMEM115 transmembrane protein 115 -0.067713
TIMP3 TIMP metallopeptidase inhibitor 3 -0.062309
ARX aristaless related homeobox -0.062309
UNC13D unc-13 homolog D (C. elegans) -0.060381
EFNA4 ephrin-A4 -0.058542
SPATA7 spermatogenesis associated 7 -0.051501
TFDP1 transcription factor Dp-1 -0.051027
CDK18 cyclin-dependent kinase 18 -0.045038
SRPRB signal recognition particle receptor, B subunit -0.042875
SPANXD SPANX family, member D -0.035979
ARMC8 armadillo repeat containing 8 -0.03352
STX12 syntaxin 12 -0.033384
C15ORF40 chromosome 15 open reading frame 40 -0.029682
GTF3C4 general transcription factor IIIC, polypeptide 4, 90kDa -0.029473
POLR3C polymerase (RNA) III (DNA directed) polypeptide C (62kD) -0.027763
WDR7 WD repeat domain 7 -0.027447
TMEM68 transmembrane protein 68 -0.022645
RHEB Ras homolog enriched in brain -0.013874
CNDP2 CNDP dipeptidase 2 (metallopeptidase M20 family) -0.008731
NBR1 neighbor of BRCA1 gene 1 -0.008438
CDKN3 cyclin-dependent kinase inhibitor 3 -0.004944
Funding