hipk2 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description homeodomain interacting protein kinase 2|This gene encodes a conserved serine/threonine kinase that is a member of the homeodomain-interacting protein kinase family. The encoded protein interacts with homeodomain transcription factors and many other transcription factors such as p53, and can function as both a corepressor and a coactivator depending on the transcription factor and its subcellular localization. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] (NCBI Entrez Gene Database, 28996)
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Genes

47 genes co-occuring with the biological term hipk2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
ATM ATM serine/threonine kinase
ATR ATR serine/threonine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
CBX4 chromobox homolog 4
CDK1 cyclin-dependent kinase 1
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CREB1 cAMP responsive element binding protein 1
CTBP1 C-terminal binding protein 1
DCAF7 DDB1 and CUL4 associated factor 7
EP300 E1A binding protein p300
FBXO3 F-box protein 3
FHL2 four and a half LIM domains 2
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
HIPK1 homeodomain interacting protein kinase 1
HIPK2 homeodomain interacting protein kinase 2
IL4 interleukin 4
ITGB4 integrin, beta 4
LGALS3 lectin, galactoside-binding, soluble, 3
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MECP2 methyl CpG binding protein 2
MIR27A microRNA 27a
MT2A metallothionein 2A
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
PAX6 paired box 6
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PML promyelocytic leukemia
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RANBP9 RAN binding protein 9
RUNX1 runt-related transcription factor 1
SENP1 SUMO1/sentrin specific peptidase 1
SIAH1 siah E3 ubiquitin protein ligase 1
SIRT1 sirtuin 1
SKI SKI proto-oncogene
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRSF3 serine/arginine-rich splicing factor 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
SUMO1 small ubiquitin-like modifier 1
TCF3 transcription factor 3
TP53 tumor protein p53
TP53INP1 tumor protein p53 inducible nuclear protein 1
TP73 tumor protein p73
VIM vimentin
WSB1 WD repeat and SOCS box containing 1
ZBTB4 zinc finger and BTB domain containing 4