histamine Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A 1H-imidazol-4-yl group substituted at position C-4 by a 2-aminoethyl group. (Chemical Entities of Biological Interest Ontology, CHEBI_18295)
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Genes

89 genes co-occuring with the biological term histamine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ADORA2A adenosine A2a receptor
ADRBK1 adrenergic, beta, receptor kinase 1
AOC1 amine oxidase, copper containing 1
APLN apelin
BCR breakpoint cluster region
CASP3 caspase 3, apoptosis-related cysteine peptidase
CCL11 chemokine (C-C motif) ligand 11
CD63 CD63 molecule
CDH5 cadherin 5, type 2 (vascular endothelium)
CHEK1 checkpoint kinase 1
CRHR1 corticotropin releasing hormone receptor 1
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL8 chemokine (C-X-C motif) ligand 8
DAO D-amino-acid oxidase
DEFB103B defensin, beta 103B
DEFB4A defensin, beta 4A
DPT dermatopontin
DRD2 dopamine receptor D2
DRD3 dopamine receptor D3
DRD4 dopamine receptor D4
ENPP3 ectonucleotide pyrophosphatase/phosphodiesterase 3
GABRB1 gamma-aminobutyric acid (GABA) A receptor, beta 1
GABRB3 gamma-aminobutyric acid (GABA) A receptor, beta 3
GSK3B glycogen synthase kinase 3 beta
HDC histidine decarboxylase
HMGB1 high mobility group box 1
HNMT histamine N-methyltransferase
HRH1 histamine receptor H1
HRH2 histamine receptor H2
HRH3 histamine receptor H3
HRH4 histamine receptor H4
HVCN1 hydrogen voltage gated channel 1
IFNG interferon, gamma
IFNL1 interferon, lambda 1
IGHE immunoglobulin heavy constant epsilon
IL13 interleukin 13
IL4 interleukin 4
IL6 interleukin 6
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
INPPL1 inositol polyphosphate phosphatase-like 1
ITGAV integrin, alpha V
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLRK1 killer cell lectin-like receptor subfamily K, member 1
LASP1 LIM and SH3 protein 1
LILRA2 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRB3 leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
MAPK3 mitogen-activated protein kinase 3
MMP2 matrix metallopeptidase 2
MMP9 matrix metallopeptidase 9
MS4A2 membrane-spanning 4-domains, subfamily A, member 2
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NGF nerve growth factor (beta polypeptide)
NOS3 nitric oxide synthase 3 (endothelial cell)
NR4A1 nuclear receptor subfamily 4, group A, member 1
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1
ORAI1 ORAI calcium release-activated calcium modulator 1
PANX1 pannexin 1
PARP1 poly (ADP-ribose) polymerase 1
POU2F2 POU class 2 homeobox 2
POU5F1 POU class 5 homeobox 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCD protein kinase C, delta
PRKG1 protein kinase, cGMP-dependent, type I
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
SLC22A2 solute carrier family 22 (organic cation transporter), member 2
SLC22A3 solute carrier family 22 (organic cation transporter), member 3
SLC29A4 solute carrier family 29 (equilibrative nucleoside transporter), member 4
SNCA synuclein, alpha (non A4 component of amyloid precursor)
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STIM1 stromal interaction molecule 1
SYK spleen tyrosine kinase
THBS1 thrombospondin 1
TNF tumor necrosis factor
TPT1 tumor protein, translationally-controlled 1
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TRPC6 transient receptor potential cation channel, subfamily C, member 6
TRPM4 transient receptor potential cation channel, subfamily M, member 4
VCAM1 vascular cell adhesion molecule 1
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A
VWF von Willebrand factor