histiocyte Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A nonmotile macrophage of extravascular tissues and especially connective tissue. (BRENDA Tissue and Enzyme Source Ontology, BTO_0000602)
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Genes

257 proteins co-occuring with the tissue histiocyte in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
CD68 CD68 molecule 3.00243
LYZ lysozyme 2.30798
CD163 CD163 molecule 1.95987
S100A9 S100 calcium binding protein A9 1.93573
GJB6 gap junction protein, beta 6, 30kDa 1.82913
ACPP acid phosphatase, prostate 1.65307
EDA ectodysplasin A 1.56818
PGM1 phosphoglucomutase 1 1.54247
CSF1R colony stimulating factor 1 receptor 1.47802
CD4 CD4 molecule 1.47802
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 1.45657
TIA1 TIA1 cytotoxic granule-associated RNA binding protein 1.41445
PTPRC protein tyrosine phosphatase, receptor type, C 1.34361
CD79A CD79a molecule, immunoglobulin-associated alpha 1.29399
ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) 1.27785
TNF tumor necrosis factor 1.22247
B3GAT1 beta-1,3-glucuronyltransferase 1 1.21535
FTL ferritin, light polypeptide 1.20511
CD34 CD34 molecule 1.19667
FTH1 ferritin, heavy polypeptide 1 1.19667
CSF1 colony stimulating factor 1 (macrophage) 1.17491
HAVCR1 hepatitis A virus cellular receptor 1 1.15362
CHIT1 chitinase 1 (chitotriosidase) 1.13634
GBA glucosidase, beta, acid 1.13014
BCL6 B-cell CLL/lymphoma 6 1.10181
STAB1 stabilin 1 1.09827
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 1.09076
IL1B interleukin 1, beta 1.07574
FSCN3 fascin actin-bundling protein 3, testicular 0.96636
FSCN2 fascin actin-bundling protein 2, retinal 0.952547
HBA1 hemoglobin, alpha 1 0.941355
ENDOU endonuclease, polyU-specific 0.93577
IL6 interleukin 6 0.935341
HBA2 hemoglobin, alpha 2 0.927192
IL2RA interleukin 2 receptor, alpha 0.921627
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) 0.903701
PAX5 paired box 5 0.90285
CD5 CD5 molecule 0.899871
PHYH phytanoyl-CoA 2-hydroxylase 0.89477
ALK anaplastic lymphoma receptor tyrosine kinase 0.884591
MPO myeloperoxidase 0.853788
FOXO4 forkhead box O4 0.847904
VSIG4 V-set and immunoglobulin domain containing 4 0.844545
CCR2 chemokine (C-C motif) receptor 2 0.842447
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64) 0.841608
ALPPL2 alkaline phosphatase, placental-like 2 0.837833
ALPL alkaline phosphatase, liver/bone/kidney 0.836995
ALPP alkaline phosphatase, placental 0.836156
NCAM1 neural cell adhesion molecule 1 0.831966
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3 0.829872
MMGT1 membrane magnesium transporter 1 0.821921
SLC48A1 solute carrier family 48 (heme transporter), member 1 0.820248
CCL2 chemokine (C-C motif) ligand 2 0.816904
FSCN1 fascin actin-bundling protein 1 0.816068
SIGLEC16 sialic acid binding Ig-like lectin 16 (gene/pseudogene) 0.813144
GUSB glucuronidase, beta 0.80563
CHID1 chitinase domain containing 1 0.803961
CD1A CD1a molecule 0.802293
ITGAD integrin, alpha D 0.795208
PRF1 perforin 1 (pore forming protein) 0.795208
CRP C-reactive protein, pentraxin-related 0.780232
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.772759
SCARB2 scavenger receptor class B, member 2 0.767783
MRC1 mannose receptor, C type 1 0.766539
TGFB1 transforming growth factor, beta 1 0.763226
MMP9 matrix metallopeptidase 9 0.7595
CTSB cathepsin B 0.757845
UNC13D unc-13 homolog D (C. elegans) 0.752057
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 0.750405
SIGLEC11 sialic acid binding Ig-like lectin 11 0.74834
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) 0.738854
CD36 CD36 molecule (thrombospondin receptor) 0.73803
AFF2 AF4/FMR2 family, member 2 0.734735
APOE apolipoprotein E 0.731031
CX3CR1 chemokine (C-X3-C motif) receptor 1 0.729797
SCARB1 scavenger receptor class B, member 1 0.728975
TNFRSF8 tumor necrosis factor receptor superfamily, member 8 0.721577
GZMB granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) 0.720755
F8 coagulation factor VIII, procoagulant component 0.719524
OAT ornithine aminotransferase 0.7146
FN1 fibronectin 1 0.7105
PAX2 paired box 2 0.697399
MLANA melan-A 0.685551
CD33 CD33 molecule 0.685143
STX11 syntaxin 11 0.682695
CR1 complement component (3b/4b) receptor 1 (Knops blood group) 0.676987
IL4 interleukin 4 0.670471
MMP1 matrix metallopeptidase 1 0.665182
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.662742
POU2AF1 POU class 2 associating factor 1 0.656648
IL1A interleukin 1, alpha 0.652589
PDGFRB platelet-derived growth factor receptor, beta polypeptide 0.652183
PCNA proliferating cell nuclear antigen 0.648938
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.642454
ICAM1 intercellular adhesion molecule 1 0.642048
KRT7 keratin 7, type II 0.641238
CCL3 chemokine (C-C motif) ligand 3 0.638404
HAMP hepcidin antimicrobial peptide 0.631123
CTSK cathepsin K 0.622235
IL10 interleukin 10 0.61699
AKAP17A A kinase (PRKA) anchor protein 17A 0.616586
MB myoglobin 0.614974
TLR4 toll-like receptor 4 0.614571
CTSD cathepsin D 0.604904
ENO2 enolase 2 (gamma, neuronal) 0.604502
CD14 CD14 molecule 0.59405
S100A8 S100 calcium binding protein A8 0.59124
CD1C CD1c molecule 0.590839
CD22 CD22 molecule 0.588832
MMP12 matrix metallopeptidase 12 0.584422
PDLIM7 PDZ and LIM domain 7 (enigma) 0.581618
SFTPD surfactant protein D 0.580017
CD7 CD7 molecule 0.576415
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 0.572418
CXCL14 chemokine (C-X-C motif) ligand 14 0.566428
CD163L1 CD163 molecule-like 1 0.554876
TRPM3 transient receptor potential cation channel, subfamily M, member 3 0.55408
SPI1 Spi-1 proto-oncogene 0.550106
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.546929
CRNN cornulin 0.546929
TP53 tumor protein p53 0.536625
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.536229
ICAM3 intercellular adhesion molecule 3 0.533065
IL2 interleukin 2 0.531484
F3 coagulation factor III (thromboplastin, tissue factor) 0.531089
PROS1 protein S (alpha) 0.527534
IFNA1 interferon, alpha 1 0.520829
IL34 interleukin 34 0.517284
MARCO macrophage receptor with collagenous structure 0.516104
ZNF335 zinc finger protein 335 0.508242
STXBP2 syntaxin binding protein 2 0.503533
MRPL1 mitochondrial ribosomal protein L1 0.496092
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.492963
TFRC transferrin receptor 0.487496
CD209 CD209 molecule 0.483596
FGR FGR proto-oncogene, Src family tyrosine kinase 0.482038
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein 0.481648
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.477367
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.475034
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 0.470763
NLRP3 NLR family, pyrin domain containing 3 0.470375
RIMS3 regulating synaptic membrane exocytosis 3 0.468824
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.465335
HP haptoglobin 0.460692
LDLR low density lipoprotein receptor 0.459918
CLEC6A C-type lectin domain family 6, member A 0.450271
HPR haptoglobin-related protein 0.449886
CCL24 chemokine (C-C motif) ligand 24 0.447192
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 0.444884
TLR2 toll-like receptor 2 0.439507
SNX17 sorting nexin 17 0.429547
KRT5 keratin 5, type II 0.429165
CD207 CD207 molecule, langerin 0.429165
LPAR6 lysophosphatidic acid receptor 6 0.429165
HMGA2 high mobility group AT-hook 2 0.427636
CD19 CD19 molecule 0.425344
LDHD lactate dehydrogenase D 0.422673
MEFV Mediterranean fever 0.420385
MITF microphthalmia-associated transcription factor 0.416957
PLIN2 perilipin 2 0.416195
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa 0.409351
DNAH8 dynein, axonemal, heavy chain 8 0.404797
CXCL9 chemokine (C-X-C motif) ligand 9 0.399114
CALD1 caldesmon 1 0.398357
ACE angiotensin I converting enzyme 0.394576
CXCL13 chemokine (C-X-C motif) ligand 13 0.393442
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 0.387404
KRT20 keratin 20, type I 0.386273
CD44 CD44 molecule (Indian blood group) 0.38439
DEFB106B defensin, beta 106B 0.384013
MTX3 metaxin 3 0.383637
TMEM200C transmembrane protein 200C 0.380627
TMEM200A transmembrane protein 200A 0.380627
IRF4 interferon regulatory factor 4 0.379875
ROMO1 reactive oxygen species modulator 1 0.379875
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.379123
PRAMEF10 PRAME family member 10 0.376119
FASLG Fas ligand (TNF superfamily, member 6) 0.373493
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 0.363766
SPIC Spi-C transcription factor (Spi-1/PU.1 related) 0.360409
TRPM2 transient receptor potential cation channel, subfamily M, member 2 0.360409
WDR76 WD repeat domain 76 0.356686
CCL17 chemokine (C-C motif) ligand 17 0.355198
TIMP1 TIMP metallopeptidase inhibitor 1 0.348148
NELFCD negative elongation factor complex member C/D 0.347778
VIM vimentin 0.346298
FCN3 ficolin (collagen/fibrinogen domain containing) 3 0.342971
MYB v-myb avian myeloblastosis viral oncogene homolog 0.33046
HAVCR2 hepatitis A virus cellular receptor 2 0.33046
HMOX1 heme oxygenase 1 0.32753
SPP1 secreted phosphoprotein 1 0.327164
MMP2 matrix metallopeptidase 2 0.32497
CALB2 calbindin 2 0.324605
BCL2 B-cell CLL/lymphoma 2 0.320956
PML promyelocytic leukemia 0.319863
IL13 interleukin 13 0.31877
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.313683
NOS2 nitric oxide synthase 2, inducible 0.31187
ADGRV1 adhesion G protein-coupled receptor V1 0.311145
FCN2 ficolin (collagen/fibrinogen domain containing lectin) 2 0.309335
CD86 CD86 molecule 0.308974
FOXP3 forkhead box P3 0.308974
CX3CL1 chemokine (C-X3-C motif) ligand 1 0.302838
C5AR1 complement component 5a receptor 1 0.30032
PLA2G15 phospholipase A2, group XV 0.29673
DOK3 docking protein 3 0.294939
FES FES proto-oncogene, tyrosine kinase 0.288514
PRSS3 protease, serine, 3 0.287447
PGM3 phosphoglucomutase 3 0.287447
IL1RN interleukin 1 receptor antagonist 0.286381
CXCR3 chemokine (C-X-C motif) receptor 3 0.286026
TYROBP TYRO protein tyrosine kinase binding protein 0.281776
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.281423
LIM2 lens intrinsic membrane protein 2, 19kDa 0.28107
NPC1 Niemann-Pick disease, type C1 0.280717
HLA-B major histocompatibility complex, class I, B 0.280012
GLYATL1 glycine-N-acyltransferase-like 1 0.277197
NPTN neuroplastin 0.271256
SH2D1A SH2 domain containing 1A 0.270909
CD58 CD58 molecule 0.270214
CMKLR1 chemerin chemokine-like receptor 1 0.266069
SLC25A30 solute carrier family 25, member 30 0.264011
FCAR Fc fragment of IgA receptor 0.257907
PSG9 pregnancy specific beta-1-glycoprotein 9 0.256568
EMP3 epithelial membrane protein 3 0.256568
HYLS1 hydrolethalus syndrome 1 0.2559
ACSBG1 acyl-CoA synthetase bubblegum family member 1 0.255234
SERPINA9 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9 0.251606
CCL8 chemokine (C-C motif) ligand 8 0.251279
TNFSF8 tumor necrosis factor (ligand) superfamily, member 8 0.250301
MST1 macrophage stimulating 1 0.249977
MERTK MER proto-oncogene, tyrosine kinase 0.249653
APOBEC3A apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A 0.248361
NT5E 5'-nucleotidase, ecto (CD73) 0.248361
CARD17 caspase recruitment domain family, member 17 0.246124
GPR15 G protein-coupled receptor 15 0.243918
BSG basigin (Ok blood group) 0.243605
SERP1 stress-associated endoplasmic reticulum protein 1 0.239007
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled 0.238406
CD37 CD37 molecule 0.235748
TG thyroglobulin 0.235457
KIF1BP KIF1 binding protein 0.235167
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled 0.233446
CXCL10 chemokine (C-X-C motif) ligand 10 0.232317
ARG1 arginase 1 0.232317
HCAR1 hydroxycarboxylic acid receptor 1 0.232317
TARP TCR gamma alternate reading frame protein 0.23176
MMP3 matrix metallopeptidase 3 0.226155
HDAC11 histone deacetylase 11 0.224645
CD63 CD63 molecule 0.223662
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 0.221291
TF transferrin 0.219264
CD40 CD40 molecule, TNF receptor superfamily member 5 0.218186
ESAM endothelial cell adhesion molecule 0.216126
IL3RA interleukin 3 receptor, alpha (low affinity) 0.214388
MBD5 methyl-CpG binding domain protein 5 0.213291
B2M beta-2-microglobulin 0.212936