histiocytosis Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description A lymphatic system disease that is characterized by an excessive number of histiocytes. (Human Disease Ontology, DOID_3405)
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Genes

36 genes co-occuring with the biological term histiocytosis in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ALK anaplastic lymphoma receptor tyrosine kinase
ARAF A-Raf proto-oncogene, serine/threonine kinase
BRAF B-Raf proto-oncogene, serine/threonine kinase
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCR6 chemokine (C-C motif) receptor 6
CCR7 chemokine (C-C motif) receptor 7
CD163 CD163 molecule
CD1A CD1a molecule
CD207 CD207 molecule, langerin
CFLAR CASP8 and FADD-like apoptosis regulator
CSF1 colony stimulating factor 1 (macrophage)
DKK1 dickkopf WNT signaling pathway inhibitor 1
FADD Fas (TNFRSF6)-associated via death domain
FLT3 fms-related tyrosine kinase 3
FLT3LG fms-related tyrosine kinase 3 ligand
IFNGR1 interferon gamma receptor 1
IL17A interleukin 17A
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit)
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase)
JAG2 jagged 2
JAK2 Janus kinase 2
KITLG KIT ligand
MAP2K1 mitogen-activated protein kinase kinase 1
MKI67 marker of proliferation Ki-67
NOTCH1 notch 1
PECAM1 platelet/endothelial cell adhesion molecule 1
PTPN6 protein tyrosine phosphatase, non-receptor type 6
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFSF11 tumor necrosis factor (ligand) superfamily, member 11
TP53 tumor protein p53