histone-lysine n-methyltransferase activity Gene Set

Dataset GO Molecular Function Annotations
Category structural or functional annotations
Type molecular function
Description Catalysis of the reaction: S-adenosyl-L-methionine + histone L-lysine = S-adenosyl-L-homocysteine + histone N6-methyl-L-lysine. The methylation of peptidyl-lysine in histones forms N6-methyl-L-lysine, N6,N6-dimethyl-L-lysine and N6,N6,N6-trimethyl-L-lysine derivatives. (Gene Ontology, GO_0018024)
External Link http://amigo.geneontology.org/amigo/term/GO:0018024
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Genes

41 genes performing the histone-lysine n-methyltransferase activity molecular function from the curated GO Molecular Function Annotations dataset.

Symbol Name
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila)
CXXC1 CXXC finger protein 1
DOT1L DOT1-like histone H3K79 methyltransferase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EZH1 enhancer of zeste 1 polycomb repressive complex 2 subunit
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit
KMT2A lysine (K)-specific methyltransferase 2A
KMT2B lysine (K)-specific methyltransferase 2B
KMT2C lysine (K)-specific methyltransferase 2C
KMT2D lysine (K)-specific methyltransferase 2D
KMT2E lysine (K)-specific methyltransferase 2E
MEN1 multiple endocrine neoplasia I
NSD1 nuclear receptor binding SET domain protein 1
PRDM2 PR domain containing 2, with ZNF domain
PRDM6 PR domain containing 6
PRDM7 PR domain containing 7
PRDM8 PR domain containing 8
PRDM9 PR domain containing 9
RBBP5 retinoblastoma binding protein 5
SETD1A SET domain containing 1A
SETD1B SET domain containing 1B
SETD2 SET domain containing 2
SETD3 SET domain containing 3
SETD7 SET domain containing (lysine methyltransferase) 7
SETD8 SET domain containing (lysine methyltransferase) 8
SETDB1 SET domain, bifurcated 1
SETDB2 SET domain, bifurcated 2
SETMAR SET domain and mariner transposase fusion gene
SMYD1 SET and MYND domain containing 1
SMYD2 SET and MYND domain containing 2
SMYD3 SET and MYND domain containing 3
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila)
WDR5 WD repeat domain 5
WDR82 WD repeat domain 82
WHSC1 Wolf-Hirschhorn syndrome candidate 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
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