history Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

368 genes co-occuring with the biological term history in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4
ACE angiotensin I converting enzyme
ACTA1 actin, alpha 1, skeletal muscle
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADA adenosine deaminase
ADAM33 ADAM metallopeptidase domain 33
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide
ADIPOQ adiponectin, C1Q and collagen domain containing
ADIPOR1 adiponectin receptor 1
ADIPOR2 adiponectin receptor 2
ADPGK ADP-dependent glucokinase
ADRB1 adrenoceptor beta 1
AFG3L2 AFG3-like AAA ATPase 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
AGXT alanine-glyoxylate aminotransferase
AHR aryl hydrocarbon receptor
AICDA activation-induced cytidine deaminase
AIP aryl hydrocarbon receptor interacting protein
AKR1C3 aldo-keto reductase family 1, member C3
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial)
ALK anaplastic lymphoma receptor tyrosine kinase
ALOX15B arachidonate 15-lipoxygenase, type B
AMD1 adenosylmethionine decarboxylase 1
AMH anti-Mullerian hormone
ANGPT1 angiopoietin 1
ANKK1 ankyrin repeat and kinase domain containing 1
ANXA5 annexin A5
APC adenomatous polyposis coli
APOA1 apolipoprotein A-I
APOB apolipoprotein B
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
APOE apolipoprotein E
AQP4 aquaporin 4
AR androgen receptor
ARG2 arginase 2
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATM ATM serine/threonine kinase
ATP7A ATPase, Cu++ transporting, alpha polypeptide
ATXN1 ataxin 1
ATXN2 ataxin 2
ATXN3 ataxin 3
ATXN7 ataxin 7
AURKA aurora kinase A
AVPR1A arginine vasopressin receptor 1A
AXIN2 axin 2
BAP1 BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
BARD1 BRCA1 associated RING domain 1
BDNF brain-derived neurotrophic factor
BMP2 bone morphogenetic protein 2
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRAP BRCA1 associated protein
BRCA1 breast cancer 1, early onset
BRCA2 breast cancer 2, early onset
BRINP3 bone morphogenetic protein/retinoic acid inducible neural-specific 3
BST1 bone marrow stromal cell antigen 1
C1QA complement component 1, q subcomponent, A chain
C3 complement component 3
C5 complement component 5
C9ORF72 chromosome 9 open reading frame 72
CASP8 caspase 8, apoptosis-related cysteine peptidase
CAT catalase
CCM2 cerebral cavernous malformation 2
CCND1 cyclin D1
CCR7 chemokine (C-C motif) receptor 7
CD1D CD1d molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CD44 CD44 molecule (Indian blood group)
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDK4 cyclin-dependent kinase 4
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CDKN2A cyclin-dependent kinase inhibitor 2A
CDKN2A-AS1 CDKN2A antisense RNA 1 (head to head)
CDX2 caudal type homeobox 2
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CETP cholesteryl ester transfer protein, plasma
CFH complement factor H
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CGA glycoprotein hormones, alpha polypeptide
CHEK2 checkpoint kinase 2
CHFR checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
CHGB chromogranin B
CHRNE cholinergic receptor, nicotinic, epsilon (muscle)
CLDN19 claudin 19
CLDN5 claudin 5
COL1A1 collagen, type I, alpha 1
COL2A1 collagen, type II, alpha 1
COL3A1 collagen, type III, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COL4A4 collagen, type IV, alpha 4
COL6A1 collagen, type VI, alpha 1
COX3
COX4I1 cytochrome c oxidase subunit IV isoform 1
CP ceruloplasmin (ferroxidase)
CRH corticotropin releasing hormone
CRP C-reactive protein, pentraxin-related
CTSC cathepsin C
CX3CL1 chemokine (C-X3-C motif) ligand 1
CXCL9 chemokine (C-X-C motif) ligand 9
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2C19 cytochrome P450, family 2, subfamily C, polypeptide 19
CYP2C8 cytochrome P450, family 2, subfamily C, polypeptide 8
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP2J2 cytochrome P450, family 2, subfamily J, polypeptide 2
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase)
DHDH dihydrodiol dehydrogenase (dimeric)
DMD dystrophin
DNM2 dynamin 2
DRD2 dopamine receptor D2
DRD4 dopamine receptor D4
EDA2R ectodysplasin A2 receptor
EGFR epidermal growth factor receptor
ELAC2 elaC ribonuclease Z 2
EPHA2 EPH receptor A2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERCC2 excision repair cross-complementation group 2
ERCC4 excision repair cross-complementation group 4
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
F2 coagulation factor II (thrombin)
F2RL2 coagulation factor II (thrombin) receptor-like 2
F5 coagulation factor V (proaccelerin, labile factor)
F7 coagulation factor VII (serum prothrombin conversion accelerator)
F8 coagulation factor VIII, procoagulant component
FABP4 fatty acid binding protein 4, adipocyte
FGA fibrinogen alpha chain
FGB fibrinogen beta chain
FGF10 fibroblast growth factor 10
FGF3 fibroblast growth factor 3
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FKBP5 FK506 binding protein 5
FLG filaggrin
FLT1 fms-related tyrosine kinase 1
FLT3 fms-related tyrosine kinase 3
FLT4 fms-related tyrosine kinase 4
FMO3 flavin containing monooxygenase 3
FMR1 fragile X mental retardation 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FOXC2 forkhead box C2
FOXP3 forkhead box P3
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GATA1 GATA binding protein 1 (globin transcription factor 1)
GBA glucosidase, beta, acid
GC group-specific component (vitamin D binding protein)
GGT1 gamma-glutamyltransferase 1
GHR growth hormone receptor
GHRL ghrelin/obestatin prepropeptide
GJB2 gap junction protein, beta 2, 26kDa
GJB6 gap junction protein, beta 6, 30kDa
GLB1 galactosidase, beta 1
GLDC glycine dehydrogenase (decarboxylating)
GOT1 glutamic-oxaloacetic transaminase 1, soluble
GP1BA glycoprotein Ib (platelet), alpha polypeptide
GPT glutamic-pyruvate transaminase (alanine aminotransferase)
GSTM1 glutathione S-transferase mu 1
GSTO2 glutathione S-transferase omega 2
GSTT1 glutathione S-transferase theta 1
HABP2 hyaluronan binding protein 2
HLA-B major histocompatibility complex, class I, B
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
HLA-G major histocompatibility complex, class I, G
HNF1A HNF1 homeobox A
HNF4A hepatocyte nuclear factor 4, alpha
HOXB13 homeobox B13
HRAS Harvey rat sarcoma viral oncogene homolog
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
HTRA1 HtrA serine peptidase 1
HTT huntingtin
IAPP islet amyloid polypeptide
ICAM1 intercellular adhesion molecule 1
IDH1 isocitrate dehydrogenase 1 (NADP+), soluble
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial
IFNG interferon, gamma
IFNL3 interferon, lambda 3
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF1R insulin-like growth factor 1 receptor
IGHM immunoglobulin heavy constant mu
IL10 interleukin 10
IL13 interleukin 13
IL18 interleukin 18
IL1B interleukin 1, beta
IL1RN interleukin 1 receptor antagonist
IL2RA interleukin 2 receptor, alpha
IL4 interleukin 4
IL6 interleukin 6
INS insulin
IRF3 interferon regulatory factor 3
IRF7 interferon regulatory factor 7
IRGM immunity-related GTPase family, M
IRS1 insulin receptor substrate 1
ITLN1 intelectin 1 (galactofuranose binding)
JAK2 Janus kinase 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KDM5D lysine (K)-specific demethylase 5D
KRAS Kirsten rat sarcoma viral oncogene homolog
LCT lactase
LEP leptin
LGALS7 lectin, galactoside-binding, soluble, 7
LIPC lipase, hepatic
LMNA lamin A/C
LMX1B LIM homeobox transcription factor 1, beta
LPA lipoprotein, Lp(a)
LRP8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
LRRK2 leucine-rich repeat kinase 2
MAOA monoamine oxidase A
MAPT microtubule-associated protein tau
MBL2 mannose-binding lectin (protein C) 2, soluble
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MCAM melanoma cell adhesion molecule
MCM2 minichromosome maintenance complex component 2
MECP2 methyl CpG binding protein 2
MEFV Mediterranean fever
MLH1 mutL homolog 1
MMP1 matrix metallopeptidase 1
MMP2 matrix metallopeptidase 2
MMP25 matrix metallopeptidase 25
MOBP myelin-associated oligodendrocyte basic protein
MPL MPL proto-oncogene, thrombopoietin receptor
MSH2 mutS homolog 2
MSH6 mutS homolog 6
MSR1 macrophage scavenger receptor 1
MT-TM tRNA
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MUTYH mutY homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYH11 myosin, heavy chain 11, smooth muscle
MYH9 myosin, heavy chain 9, non-muscle
NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase)
NBEA neurobeachin
NDP Norrie disease (pseudoglioma)
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
NKX2-5 NK2 homeobox 5
NOD2 nucleotide-binding oligomerization domain containing 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NOTCH3 notch 3
NPC2 Niemann-Pick disease, type C2
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NPPB natriuretic peptide B
NPR1 natriuretic peptide receptor 1
NPR3 natriuretic peptide receptor 3
NPY neuropeptide Y
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR5A1 nuclear receptor subfamily 5, group A, member 1
NRG1 neuregulin 1
OAZ1 ornithine decarboxylase antizyme 1
OAZ2 ornithine decarboxylase antizyme 2
OXTR oxytocin receptor
PAEP progestagen-associated endometrial protein
PAH phenylalanine hydroxylase
PALB2 partner and localizer of BRCA2
PANK2 pantothenate kinase 2
PARK2 parkin RBR E3 ubiquitin protein ligase
PCBP1 poly(rC) binding protein 1
PCDH19 protocadherin 19
PEBP1 phosphatidylethanolamine binding protein 1
PGF placental growth factor
PGR progesterone receptor
PHF6 PHD finger protein 6
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLCE1 phospholipase C, epsilon 1
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PMCH pro-melanin-concentrating hormone
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
PMS2 PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
PNLIP pancreatic lipase
POLG polymerase (DNA directed), gamma
POMC proopiomelanocortin
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha
PRNP prion protein
PROC protein C (inactivator of coagulation factors Va and VIIIa)
PROS1 protein S (alpha)
PRRT2 proline-rich transmembrane protein 2
PSEN1 presenilin 1
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPRN protein tyrosine phosphatase, receptor type, N
PTX3 pentraxin 3, long
RAD51C RAD51 paralog C
RB1 retinoblastoma 1
RET ret proto-oncogene
RETN resistin
RIC3 RIC3 acetylcholine receptor chaperone
RLN1 relaxin 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RTEL1 regulator of telomere elongation helicase 1
RUNX3 runt-related transcription factor 3
RXRB retinoid X receptor, beta
SATB1 SATB homeobox 1
SCN1A sodium channel, voltage gated, type I alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SELPLG selectin P ligand
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1
SFTPA1 surfactant protein A1
SGCE sarcoglycan, epsilon
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC26A4 solute carrier family 26 (anion exchanger), member 4
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1
SMAD4 SMAD family member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SNORD115-1 small nucleolar RNA, C/D box 115-1
SPAST spastin
SPP1 secreted phosphoprotein 1
SQSTM1 sequestosome 1
SRSF1 serine/arginine-rich splicing factor 1
SSTR3 somatostatin receptor 3
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STK11 serine/threonine kinase 11
STX16 syntaxin 16
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TARDBP TAR DNA binding protein
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TGFB1 transforming growth factor, beta 1
THBD thrombomodulin
TLR2 toll-like receptor 2
TLR4 toll-like receptor 4
TLR6 toll-like receptor 6
TLR7 toll-like receptor 7
TLR9 toll-like receptor 9
TMC6 transmembrane channel-like 6
TMC8 transmembrane channel-like 8
TNF tumor necrosis factor
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF13C tumor necrosis factor receptor superfamily, member 13C
TNFSF14 tumor necrosis factor (ligand) superfamily, member 14
TOP2A topoisomerase (DNA) II alpha 170kDa
TP53 tumor protein p53
TPH1 tryptophan hydroxylase 1
TPH2 tryptophan hydroxylase 2
TPSAB1 tryptase alpha/beta 1
TRA T cell receptor alpha locus
TRG T cell receptor gamma locus
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSC1 tuberous sclerosis 1
TSC2 tuberous sclerosis 2
TTR transthyretin
UBASH3A ubiquitin associated and SH3 domain containing A
UBE3A ubiquitin protein ligase E3A
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VEGFA vascular endothelial growth factor A
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WFS1 Wolfram syndrome 1 (wolframin)
WT1 Wilms tumor 1
WWOX WW domain containing oxidoreductase
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3