hmga1 Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description high mobility group AT-hook 1|This gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 3159)
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Genes

42 genes co-occuring with the biological term hmga1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
BRCA1 breast cancer 1, early onset
CAPRIN1 cell cycle associated protein 1
CCNB2 cyclin B2
CDK1 cyclin-dependent kinase 1
CDKN2A cyclin-dependent kinase inhibitor 2A
CRYAB crystallin, alpha B
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
E2F1 E2F transcription factor 1
ESR1 estrogen receptor 1
FMNL2 formin-like 2
HAND1 heart and neural crest derivatives expressed 1
HIPK2 homeodomain interacting protein kinase 2
HMGA1 high mobility group AT-hook 1
HMGA2 high mobility group AT-hook 2
IGFBP1 insulin-like growth factor binding protein 1
IGFBP3 insulin-like growth factor binding protein 3
INSR insulin receptor
KITLG KIT ligand
LARP7 La ribonucleoprotein domain family, member 7
MIR137 microRNA 137
MIR15A microRNA 15a
MIR16-1 microRNA 16-1
MIR195 microRNA 195
MIR196A1 microRNA 196a-1
MIR222 microRNA 222
MIR26A1 microRNA 26a-1
MIR26B microRNA 26b
MIR296 microRNA 296
MIRLET7A1 microRNA let-7a-1
MIRLET7B microRNA let-7b
MMP2 matrix metallopeptidase 2
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
NOS2 nitric oxide synthase 2, inducible
POU1F1 POU class 1 homeobox 1
POU2F1 POU class 2 homeobox 1
POU2F2 POU class 2 homeobox 2
PRKCE protein kinase C, epsilon
RB1 retinoblastoma 1
RN7SK RNA, 7SK small nuclear
SFTPD surfactant protein D
WNT1 wingless-type MMTV integration site family, member 1