hnf1b_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS1499
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Genes

259 genes differentially expressed following the hnf1b_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.210226
GAB1 GRB2-associated binding protein 1 0.205895
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.204371
NLE1 notchless homolog 1 (Drosophila) 0.203611
ALDH1B1 aldehyde dehydrogenase 1 family, member B1 0.20149
CAT catalase 0.200851
ARID4B AT rich interactive domain 4B (RBP1-like) 0.197514
MFN1 mitofusin 1 0.197382
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.197353
RABL6 RAB, member RAS oncogene family-like 6 0.196444
ABCA4 ATP-binding cassette, sub-family A (ABC1), member 4 0.195661
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) 0.195259
SEP15 15 kDa selenoprotein 0.192113
ATP2C1 ATPase, Ca++ transporting, type 2C, member 1 0.191377
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 0.189551
LPIN1 lipin 1 0.189327
MUC2 mucin 2, oligomeric mucus/gel-forming 0.188924
DLK2 delta-like 2 homolog (Drosophila) 0.188502
ANO3 anoctamin 3 0.185919
OR1F1 olfactory receptor, family 1, subfamily F, member 1 0.180304
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.178664
C1GALT1C1 C1GALT1-specific chaperone 1 0.175402
SHPK sedoheptulokinase 0.171335
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.170639
PCDHB17P protocadherin beta 17 pseudogene 0.170129
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.162046
CENPM centromere protein M 0.162015
GRM5 glutamate receptor, metabotropic 5 0.158172
CD28 CD28 molecule 0.155215
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 0.153783
SPATA2 spermatogenesis associated 2 0.152207
ZFP37 ZFP37 zinc finger protein 0.15043
APOC4 apolipoprotein C-IV 0.147638
ERP44 endoplasmic reticulum protein 44 0.147151
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1 0.14343
TKTL1 transketolase-like 1 0.138781
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.138607
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2 0.137976
CLDN18 claudin 18 0.136307
FXYD7 FXYD domain containing ion transport regulator 7 0.13524
CRISP1 cysteine-rich secretory protein 1 0.134121
R3HDM4 R3H domain containing 4 0.131138
CHRNG cholinergic receptor, nicotinic, gamma (muscle) 0.129285
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.129191
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal) 0.127219
RPL26L1 ribosomal protein L26-like 1 0.125997
FKSG49 FKSG49 0.12375
ADD3 adducin 3 (gamma) 0.123485
PCDH1 protocadherin 1 0.121924
BPTF bromodomain PHD finger transcription factor 0.115841
VPRBP Vpr (HIV-1) binding protein 0.114927
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1 0.112568
MGST3 microsomal glutathione S-transferase 3 0.11223
MYL4 myosin, light chain 4, alkali; atrial, embryonic 0.111367
ERN2 endoplasmic reticulum to nucleus signaling 2 0.109065
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 0.108346
SPTLC2 serine palmitoyltransferase, long chain base subunit 2 0.105307
MAPT microtubule-associated protein tau 0.103862
HOXA11 homeobox A11 0.103057
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.09884
STX17 syntaxin 17 0.09875
CNTLN centlein, centrosomal protein 0.097848
NF1 neurofibromin 1 0.097683
EPHB1 EPH receptor B1 0.097608
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding) 0.093509
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1 0.091503
SAA4 serum amyloid A4, constitutive 0.090392
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 0.088031
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.082925
CA4 carbonic anhydrase IV 0.081605
CCL19 chemokine (C-C motif) ligand 19 0.08062
MSRB2 methionine sulfoxide reductase B2 0.078573
UBAP2L ubiquitin associated protein 2-like 0.078286
RAD1 RAD1 checkpoint DNA exonuclease 0.077625
BMP8B bone morphogenetic protein 8b 0.075622
ACTR1A ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) 0.073021
A4GALT alpha 1,4-galactosyltransferase 0.072327
APLP2 amyloid beta (A4) precursor-like protein 2 0.07148
SPIN2B spindlin family, member 2B 0.07086
USP9Y ubiquitin specific peptidase 9, Y-linked 0.068126
ATF6B activating transcription factor 6 beta 0.063824
RBM23 RNA binding motif protein 23 0.059225
LMO7 LIM domain 7 0.059102
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.058654
SPAM1 sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) 0.056803
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group) 0.049901
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.046456
ARHGAP25 Rho GTPase activating protein 25 0.045421
STOML1 stomatin (EPB72)-like 1 0.043479
ACTC1 actin, alpha, cardiac muscle 1 0.042712
IL1RL1 interleukin 1 receptor-like 1 0.039778
CA12 carbonic anhydrase XII 0.038378
SYK spleen tyrosine kinase 0.03785
THBS1 thrombospondin 1 0.037765
CLCN1 chloride channel, voltage-sensitive 1 0.036681
MKRN3 makorin ring finger protein 3 0.036404
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2 0.035713
HS1BP3 HCLS1 binding protein 3 0.034089
TBPL1 TBP-like 1 0.034008
FAM76A family with sequence similarity 76, member A 0.033897
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 0.033322
FGB fibrinogen beta chain 0.029793
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11 0.025575
TBX6 T-box 6 0.018875
LAMA1 laminin, alpha 1 0.018669
PTPRD protein tyrosine phosphatase, receptor type, D 0.015211
TMEM115 transmembrane protein 115 0.009051
MCFD2 multiple coagulation factor deficiency 2 0.004984
UBL4A ubiquitin-like 4A 0.002204

decreased expression

Symbol Name Standardized Value
RPS7 ribosomal protein S7 -1.31995
CERS2 ceramide synthase 2 -1.31457
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -1.29964
SLC30A3 solute carrier family 30 (zinc transporter), member 3 -1.27249
GPX1 glutathione peroxidase 1 -1.22945
SETD5 SET domain containing 5 -1.1822
PDLIM5 PDZ and LIM domain 5 -1.16675
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit -1.15966
DSC2 desmocollin 2 -1.1386
SOX9 SRY (sex determining region Y)-box 9 -1.13572
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 -1.12474
ALPPL2 alkaline phosphatase, placental-like 2 -1.12474
VEGFA vascular endothelial growth factor A -1.11429
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) -1.1115
NR4A2 nuclear receptor subfamily 4, group A, member 2 -1.10525
HNRNPM heterogeneous nuclear ribonucleoprotein M -1.08889
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 -1.06593
PDCD2 programmed cell death 2 -1.0443
NIF3L1 NIF3 NGG1 interacting factor 3-like 1 (S. cerevisiae) -1.03286
CLIC4 chloride intracellular channel 4 -1.02729
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1 -1.02399
CDA cytidine deaminase -1.01842
GAS6 growth arrest-specific 6 -1.01828
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.994439
CTRB2 chymotrypsinogen B2 -0.966698
CD93 CD93 molecule -0.951969
SLC6A15 solute carrier family 6 (neutral amino acid transporter), member 15 -0.930937
ANGPT4 angiopoietin 4 -0.910754
CCNC cyclin C -0.903029
ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) -0.89404
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) -0.888645
C1ORF50 chromosome 1 open reading frame 50 -0.864919
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker) -0.837735
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) -0.828977
HOXA5 homeobox A5 -0.820961
ALMS1 Alstrom syndrome protein 1 -0.799649
PEX5 peroxisomal biogenesis factor 5 -0.789205
SYT17 synaptotagmin XVII -0.779298
NAT6 N-acetyltransferase 6 (GCN5-related) -0.757671
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.754185
NRP1 neuropilin 1 -0.750424
MRPS31 mitochondrial ribosomal protein S31 -0.74516
BBC3 BCL2 binding component 3 -0.704178
ENSA endosulfine alpha -0.699956
GAS7 growth arrest-specific 7 -0.686521
GFI1 growth factor independent 1 transcription repressor -0.67918
WDHD1 WD repeat and HMG-box DNA binding protein 1 -0.672866
CYLD cylindromatosis (turban tumor syndrome) -0.671695
SPEN spen family transcriptional repressor -0.666412
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) -0.663319
COL7A1 collagen, type VII, alpha 1 -0.660018
TM4SF1 transmembrane 4 L six family member 1 -0.655008
COL5A3 collagen, type V, alpha 3 -0.652002
SMAD2 SMAD family member 2 -0.649022
RAB31 RAB31, member RAS oncogene family -0.643874
GSR glutathione reductase -0.640817
NOTCH1 notch 1 -0.637508
PPP1R7 protein phosphatase 1, regulatory subunit 7 -0.620335
DYRK1B dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B -0.616883
PRR14 proline rich 14 -0.61374
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9 -0.609639
GOLGA7 golgin A7 -0.600959
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa -0.593891
MRPL9 mitochondrial ribosomal protein L9 -0.583838
HEXIM1 hexamethylene bis-acetamide inducible 1 -0.571877
HIPK3 homeodomain interacting protein kinase 3 -0.566682
ZNF24 zinc finger protein 24 -0.563754
RPS6KB1 ribosomal protein S6 kinase, 70kDa, polypeptide 1 -0.560702
LOC100287275 C1QTNF9B antisense RNA 1 pseudogene -0.549938
IDE insulin-degrading enzyme -0.543412
ZNF184 zinc finger protein 184 -0.526438
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 -0.523351
SFN stratifin -0.520547
NQO1 NAD(P)H dehydrogenase, quinone 1 -0.519709
DUSP4 dual specificity phosphatase 4 -0.517643
RSRC2 arginine/serine-rich coiled-coil 2 -0.515455
RAB7A RAB7A, member RAS oncogene family -0.512222
TRAPPC3 trafficking protein particle complex 3 -0.510401
INTS7 integrator complex subunit 7 -0.509781
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 -0.503043
CFDP1 craniofacial development protein 1 -0.502747
RAB17 RAB17, member RAS oncogene family -0.500849
LOC284244 uncharacterized LOC284244 -0.499883
RANGAP1 Ran GTPase activating protein 1 -0.478563
PTPRO protein tyrosine phosphatase, receptor type, O -0.477118
MARCKSL1 MARCKS-like 1 -0.47701
YY1 YY1 transcription factor -0.476112
USP34 ubiquitin specific peptidase 34 -0.465513
RHD Rh blood group, D antigen -0.463512
BLZF1 basic leucine zipper nuclear factor 1 -0.457633
ITGB4 integrin, beta 4 -0.452081
OSBPL3 oxysterol binding protein-like 3 -0.448275
XPA xeroderma pigmentosum, complementation group A -0.446737
UBE3A ubiquitin protein ligase E3A -0.445512
CD99 CD99 molecule -0.445051
CHRM3 cholinergic receptor, muscarinic 3 -0.443969
C21ORF33 chromosome 21 open reading frame 33 -0.442543
PNN pinin, desmosome associated protein -0.439248
DYSF dysferlin -0.438617
CDYL chromodomain protein, Y-like -0.437669
FBXO21 F-box protein 21 -0.434813
PDE4DIP phosphodiesterase 4D interacting protein -0.433803
CCT8L2 chaperonin containing TCP1, subunit 8 (theta)-like 2 -0.065524
NFE2L2 nuclear factor, erythroid 2-like 2 -0.062477
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) -0.061788
FKBP1A FK506 binding protein 1A, 12kDa -0.058491
AP3D1 adaptor-related protein complex 3, delta 1 subunit -0.056336
MED7 mediator complex subunit 7 -0.052707
RAP2A RAP2A, member of RAS oncogene family -0.052688
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) -0.052141
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) -0.051179
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 -0.05112
CEBPD CCAAT/enhancer binding protein (C/EBP), delta -0.04985
KIAA0922 KIAA0922 -0.048209
ECHDC3 enoyl CoA hydratase domain containing 3 -0.047848
NRL neural retina leucine zipper -0.047105
GOT1 glutamic-oxaloacetic transaminase 1, soluble -0.042603
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) -0.041104
WDR61 WD repeat domain 61 -0.040438
FICD FIC domain containing -0.039557
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -0.038062
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1 -0.035017
HCG4 HLA complex group 4 (non-protein coding) -0.034803
MKRN2 makorin ring finger protein 2 -0.034609
ZNF415 zinc finger protein 415 -0.034545
GLRB glycine receptor, beta -0.034437
PCM1 pericentriolar material 1 -0.033814
PARD6A par-6 family cell polarity regulator alpha -0.033621
B3GAT3 beta-1,3-glucuronyltransferase 3 -0.032174
AQP9 aquaporin 9 -0.032022
PTPRF protein tyrosine phosphatase, receptor type, F -0.031805
CAMK2B calcium/calmodulin-dependent protein kinase II beta -0.02976
FABP7 fatty acid binding protein 7, brain -0.028537
IAPP islet amyloid polypeptide -0.025364
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.023121
GNAS GNAS complex locus -0.021935
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 -0.019243
TTC39A tetratricopeptide repeat domain 39A -0.016804
FYB FYN binding protein -0.012002
TMEM199 transmembrane protein 199 -0.011021
VCAN versican -0.010906
MYD88 myeloid differentiation primary response 88 -0.010194
IL2 interleukin 2 -0.007781
PPP2R5D protein phosphatase 2, regulatory subunit B', delta -0.004569
GRIK2 glutamate receptor, ionotropic, kainate 2 -0.003366
RNASEH1 ribonuclease H1 -0.003113
PDLIM4 PDZ and LIM domain 4 -0.002042
DAZAP2 DAZ associated protein 2 -0.00195
TREX2 three prime repair exonuclease 2 -0.00195
PHTF2 putative homeodomain transcription factor 2 -4.3E-5
Funding