hnf4a Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
Description hepatocyte nuclear factor 4, alpha|The protein encoded by this gene is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I. Alternative splicing of this gene results in multiple transcript variants encoding several different isoforms. [provided by RefSeq, Apr 2012] (NCBI Entrez Gene Database, 3172)
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Genes

26 genes co-occuring with the biological term hnf4a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ABCG5 ATP-binding cassette, sub-family G (WHITE), member 5
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8
CRP C-reactive protein, pentraxin-related
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP7A1 cytochrome P450, family 7, subfamily A, polypeptide 1
DGAT1 diacylglycerol O-acyltransferase 1
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FOXO1 forkhead box O1
GCK glucokinase (hexokinase 4)
HADH hydroxyacyl-CoA dehydrogenase
HNF1A HNF1 homeobox A
HNF1B HNF1 homeobox B
HNF4A hepatocyte nuclear factor 4, alpha
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK8 mitogen-activated protein kinase 8
MIR21 microRNA 21
MIR34A microRNA 34a
MIR34C microRNA 34c
MIR449A microRNA 449a
PPARG peroxisome proliferator-activated receptor gamma
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
REG1A regenerating islet-derived 1 alpha
SHBG sex hormone-binding globulin
WFS1 Wolfram syndrome 1 (wolframin)