hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS1916
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Genes

946 genes differentially expressed following the hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
MTTP microsomal triglyceride transfer protein 2.19073
LRPPRC leucine-rich pentatricopeptide repeat containing 2.19073
ACAT1 acetyl-CoA acetyltransferase 1 2.19073
CLDN1 claudin 1 2.19073
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 2.19073
GALK1 galactokinase 1 2.19073
GPD1 glycerol-3-phosphate dehydrogenase 1 (soluble) 2.19073
PXMP4 peroxisomal membrane protein 4, 24kDa 2.19073
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 2.19073
CFI complement factor I 2.19073
BHMT betaine--homocysteine S-methyltransferase 2.19073
SCP2 sterol carrier protein 2 2.19073
DGAT2 diacylglycerol O-acyltransferase 2 2.17138
GLDC glycine dehydrogenase (decarboxylating) 2.15066
NDUFA12 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 2.15066
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 2.15066
TTR transthyretin 2.15066
F13B coagulation factor XIII, B polypeptide 2.15066
CFB complement factor B 2.15066
FMO1 flavin containing monooxygenase 1 2.06264
KCNQ4 potassium channel, voltage gated KQT-like subfamily Q, member 4 2.05294
C19ORF12 chromosome 19 open reading frame 12 2.03861
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4 2.03861
TMEM150A transmembrane protein 150A 2.03861
SLCO1B3 solute carrier organic anion transporter family, member 1B3 2.03861
ANKRD23 ankyrin repeat domain 23 2.03861
LRRC3 leucine rich repeat containing 3 2.02958
KNG1 kininogen 1 2.02222
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.02222
TTC36 tetratricopeptide repeat domain 36 2.01428
PIPOX pipecolic acid oxidase 2.00909
ERBB3 erb-b2 receptor tyrosine kinase 3 2.00639
PXMP2 peroxisomal membrane protein 2, 22kDa 2.00639
DECR2 2,4-dienoyl CoA reductase 2, peroxisomal 2.00639
COX5B cytochrome c oxidase subunit Vb 2.00639
BHMT2 betaine--homocysteine S-methyltransferase 2 2.00639
F10 coagulation factor X 2.00015
PSD2 pleckstrin and Sec7 domain containing 2 2.00015
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 1.99521
ONECUT1 one cut homeobox 1 1.98433
ABTB2 ankyrin repeat and BTB (POZ) domain containing 2 1.98433
CHDH choline dehydrogenase 1.98433
GC group-specific component (vitamin D binding protein) 1.94324
PEX19 peroxisomal biogenesis factor 19 1.92585
APOA2 apolipoprotein A-II 1.91019
ALDH1L1 aldehyde dehydrogenase 1 family, member L1 1.90691
ECHDC3 enoyl CoA hydratase domain containing 3 1.90691
BDH1 3-hydroxybutyrate dehydrogenase, type 1 1.90007
HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 1.90007
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1 1.87156
NIPSNAP1 nipsnap homolog 1 (C. elegans) 1.85756
EPHX2 epoxide hydrolase 2, cytoplasmic 1.85756
CPN2 carboxypeptidase N, polypeptide 2 1.85756
SLC7A2 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 1.85374
SERPING1 serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 1.85109
ACAD11 acyl-CoA dehydrogenase family, member 11 1.85109
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 1.83642
LPIN1 lipin 1 1.81854
GSTA4 glutathione S-transferase alpha 4 1.8002
DPYS dihydropyrimidinase 1.8002
C2 complement component 2 1.77341
PPARA peroxisome proliferator-activated receptor alpha 1.75884
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3 1.75884
LURAP1L leucine rich adaptor protein 1-like 1.75884
ASL argininosuccinate lyase 1.75884
GLYCTK glycerate kinase 1.73849
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) 1.73115
IYD iodotyrosine deiodinase 1.73115
FENDRR FOXF1 adjacent non-coding developmental regulatory RNA 1.7135
BCHE butyrylcholinesterase 1.7135
SAR1B secretion associated, Ras related GTPase 1B 1.7135
CIDEB cell death-inducing DFFA-like effector b 1.70802
SPPL2A signal peptide peptidase like 2A 1.70802
DMGDH dimethylglycine dehydrogenase 1.70802
GJB1 gap junction protein, beta 1, 32kDa 1.70492
CCS copper chaperone for superoxide dismutase 1.70492
GYS2 glycogen synthase 2 (liver) 1.70492
PLA2G12B phospholipase A2, group XIIB 1.70492
PPAP2B phosphatidic acid phosphatase type 2B 1.68214
SERPINC1 serpin peptidase inhibitor, clade C (antithrombin), member 1 1.68214
DAO D-amino-acid oxidase 1.68214
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.68214
LECT2 leukocyte cell-derived chemotaxin 2 1.68184
PZP pregnancy-zone protein 1.67114
SRSF2 serine/arginine-rich splicing factor 2 1.64565
C21ORF2 chromosome 21 open reading frame 2 1.64565
SALL1 spalt-like transcription factor 1 1.64565
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13 1.64565
CDO1 cysteine dioxygenase type 1 1.64565
TTLL3 tubulin tyrosine ligase-like family member 3 1.64565
UGT2A3 UDP glucuronosyltransferase 2 family, polypeptide A3 1.64565
MSRA methionine sulfoxide reductase A 1.64565
PROZ protein Z, vitamin K-dependent plasma glycoprotein 1.64388
PANK1 pantothenate kinase 1 1.5966
C11ORF54 chromosome 11 open reading frame 54 1.59257
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 1.56306
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain 1.56306
HPX hemopexin 1.56306
FABP1 fatty acid binding protein 1, liver 1.53541
USP8 ubiquitin specific peptidase 8 1.53541
HINT2 histidine triad nucleotide binding protein 2 1.53541
LIPC lipase, hepatic 1.53541
PPAPDC2 phosphatidic acid phosphatase type 2 domain containing 2 1.53541
PTPMT1 protein tyrosine phosphatase, mitochondrial 1 1.53541
PECR peroxisomal trans-2-enoyl-CoA reductase 1.53541
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 1.53541
TMEM205 transmembrane protein 205 1.53541
TOMM70A translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) 1.53541
TECR trans-2,3-enoyl-CoA reductase 1.53541
AGMAT agmatine ureohydrolase (agmatinase) 1.53334
PEMT phosphatidylethanolamine N-methyltransferase 1.53334
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 1.53334
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 1.53334
RAB4A RAB4A, member RAS oncogene family 1.53334
PC pyruvate carboxylase 1.52605
OCLN occludin 1.52416
OTC ornithine carbamoyltransferase 1.5136
ETFDH electron-transferring-flavoprotein dehydrogenase 1.5136
HPD 4-hydroxyphenylpyruvate dioxygenase 1.48822
ROGDI rogdi homolog (Drosophila) 1.48822
GSTA3 glutathione S-transferase alpha 3 1.48822
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13 1.48822
STARD5 StAR-related lipid transfer (START) domain containing 5 1.4834
PPM1K protein phosphatase, Mg2+/Mn2+ dependent, 1K 1.4834
TTL tubulin tyrosine ligase 1.47471
SEPHS2 selenophosphate synthetase 2 1.47471
GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) 1.46195
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 1.46195
APOA1 apolipoprotein A-I 1.45288
CDC14B cell division cycle 14B 1.45288
F2 coagulation factor II (thrombin) 1.45288
GPLD1 glycosylphosphatidylinositol specific phospholipase D1 1.45288
ACOX2 acyl-CoA oxidase 2, branched chain 1.45288
TM7SF2 transmembrane 7 superfamily member 2 1.45055
TSSK4 testis-specific serine kinase 4 1.41772
AHSG alpha-2-HS-glycoprotein 1.41772
HSD3B7 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 1.40416
RNF217 ring finger protein 217 1.40281
LEAP2 liver expressed antimicrobial peptide 2 1.38235
EPB41L5 erythrocyte membrane protein band 4.1 like 5 1.38235
LUC7L LUC7-like (S. cerevisiae) 1.38235
CRP C-reactive protein, pentraxin-related 1.38235
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 1.38235
STIL SCL/TAL1 interrupting locus 1.38235
CD9 CD9 molecule 1.3747
BPHL biphenyl hydrolase-like (serine hydrolase) 1.3747
TNFRSF4 tumor necrosis factor receptor superfamily, member 4 1.3747
SEC24A SEC24 family member A 1.3747
CIART circadian associated repressor of transcription 1.37365
CGNL1 cingulin-like 1 1.37365
DCBLD1 discoidin, CUB and LCCL domain containing 1 1.31296
ACTRT2 actin-related protein T2 1.31296
LONP2 lon peptidase 2, peroxisomal 1.3111
TTPA tocopherol (alpha) transfer protein 1.3111
AKAP1 A kinase (PRKA) anchor protein 1 1.30723
AK4 adenylate kinase 4 1.30095
ITK IL2-inducible T-cell kinase 1.29238
ARHGAP27 Rho GTPase activating protein 27 1.29238
SYNPO2 synaptopodin 2 1.29238
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 1.26147
CORO1C coronin, actin binding protein, 1C 1.26105
ADI1 acireductone dioxygenase 1 1.25588
MAGEE1 melanoma antigen family E1 1.23088
CAPN15 calpain 15 1.23088
HGD homogentisate 1,2-dioxygenase 1.23088
DUSP27 dual specificity phosphatase 27 (putative) 1.23088
TEX9 testis expressed 9 1.23088
MYCT1 myc target 1 1.22745
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 1.22745
SNHG7 small nucleolar RNA host gene 7 1.20918
CFH complement factor H 1.20918
GFRA3 GDNF family receptor alpha 3 1.20918
GPC4 glypican 4 1.18673
WIPF1 WAS/WASL interacting protein family, member 1 1.17885
OBSL1 obscurin-like 1 1.17885
FXYD4 FXYD domain containing ion transport regulator 4 1.17518
C3 complement component 3 1.17518
JUNB jun B proto-oncogene 1.17518
CCBL2 cysteine conjugate-beta lyase 2 1.17518
CCDC171 coiled-coil domain containing 171 1.17518
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 1.15838
GTF2B general transcription factor IIB 1.15838
DERL2 derlin 2 1.1495
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 1.1495
ANGPTL4 angiopoietin-like 4 1.1495
GRB7 growth factor receptor-bound protein 7 1.1495
VWCE von Willebrand factor C and EGF domains 1.1495
SULF2 sulfatase 2 1.1495
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 1.1495
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 1.1495
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 1.12663
MPZ myelin protein zero 1.12663
KCNA1 potassium channel, voltage gated shaker related subfamily A, member 1 1.12663
LHFPL2 lipoma HMGIC fusion partner-like 2 1.12663
APOM apolipoprotein M 1.12663
HP haptoglobin 1.12629
SLC38A3 solute carrier family 38, member 3 1.12617
PPP1R36 protein phosphatase 1, regulatory subunit 36 1.12617
TFR2 transferrin receptor 2 1.11841
MAT1A methionine adenosyltransferase I, alpha 1.11841
CD302 CD302 molecule 1.11299
ACOT12 acyl-CoA thioesterase 12 1.09521
ACADVL acyl-CoA dehydrogenase, very long chain 1.09521
GGACT gamma-glutamylamine cyclotransferase 1.09521
DTX1 deltex 1, E3 ubiquitin ligase 1.09521
NUDT12 nudix (nucleoside diphosphate linked moiety X)-type motif 12 1.07268
GOT1 glutamic-oxaloacetic transaminase 1, soluble 1.07268
GCSH glycine cleavage system protein H (aminomethyl carrier) 1.06609
ADTRP androgen-dependent TFPI-regulating protein 1.04862
ARSG arylsulfatase G 1.02511
PON1 paraoxonase 1 1.02414
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 1.02414
MYO5B myosin VB 1.00227
LAMP2 lysosomal-associated membrane protein 2 0.999451
TXNDC15 thioredoxin domain containing 15 0.999451
MTMR10 myotubularin related protein 10 0.999451
KCNC3 potassium channel, voltage gated Shaw related subfamily C, member 3 0.998143
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase) 0.969285
FBP1 fructose-1,6-bisphosphatase 1 0.969285
SULT1A1 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 0.969285
CTSL cathepsin L 0.955416
FADD Fas (TNFRSF6)-associated via death domain 0.953474
PALM2 paralemmin 2 0.931277
PPAP2C phosphatidic acid phosphatase type 2C 0.931277
TSPAN12 tetraspanin 12 0.929518
LIPA lipase A, lysosomal acid, cholesterol esterase 0.923482
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.923482
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.923482
PARN poly(A)-specific ribonuclease 0.923482
FUZ fuzzy planar cell polarity protein 0.923482
F9 coagulation factor IX 0.912171
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.901774
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.901774
PRDX5 peroxiredoxin 5 0.901648
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) 0.897093
ARHGAP5 Rho GTPase activating protein 5 0.88414
TFPI2 tissue factor pathway inhibitor 2 0.88065
MGST1 microsomal glutathione S-transferase 1 0.860017
FTCD formimidoyltransferase cyclodeaminase 0.85866
SLC39A14 solute carrier family 39 (zinc transporter), member 14 0.832004
AMDHD1 amidohydrolase domain containing 1 0.832004
PCSK4 proprotein convertase subtilisin/kexin type 4 0.832004
PHYH phytanoyl-CoA 2-hydroxylase 0.832004
HPS3 Hermansky-Pudlak syndrome 3 0.832004
RRBP1 ribosome binding protein 1 0.832004
LDHB lactate dehydrogenase B 0.826151
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.826151
BECN1 beclin 1, autophagy related 0.826151
IP6K2 inositol hexakisphosphate kinase 2 0.826151
HAO2 hydroxyacid oxidase 2 (long chain) 0.826151
VWA8 von Willebrand factor A domain containing 8 0.826151
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.826151
KBTBD8 kelch repeat and BTB (POZ) domain containing 8 0.826151
HFE2 hemochromatosis type 2 (juvenile) 0.826151
KLF15 Kruppel-like factor 15 0.824074
PGRMC1 progesterone receptor membrane component 1 0.824074
THNSL2 threonine synthase-like 2 (S. cerevisiae) 0.824074
C8G complement component 8, gamma polypeptide 0.823132
YLPM1 YLP motif containing 1 0.814514
E2F5 E2F transcription factor 5, p130-binding 0.807672
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.805183
C1ORF35 chromosome 1 open reading frame 35 0.805183
CYB5A cytochrome b5 type A (microsomal) 0.805183
POLH polymerase (DNA directed), eta 0.805183
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.805183
MGAM maltase-glucoamylase 0.805183
GPER1 G protein-coupled estrogen receptor 1 0.805183
GSN gelsolin 0.780906
CXADR coxsackie virus and adenovirus receptor 0.76972
TMEM57 transmembrane protein 57 0.763663
HACL1 2-hydroxyacyl-CoA lyase 1 0.763663
CMBL carboxymethylenebutenolidase homolog (Pseudomonas) 0.763663
MKRN2OS MKRN2 opposite strand 0.763663
SARDH sarcosine dehydrogenase 0.762326
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.748607
ACSL1 acyl-CoA synthetase long-chain family member 1 0.72303
FBXO31 F-box protein 31 0.72303
PROC protein C (inactivator of coagulation factors Va and VIIIa) 0.72303
PLA1A phospholipase A1 member A 0.72303
MST1 macrophage stimulating 1 0.722279
CHRAC1 chromatin accessibility complex 1 0.71667
LCAT lecithin-cholesterol acyltransferase 0.71667
HOXD11 homeobox D11 0.71667
SLC27A2 solute carrier family 27 (fatty acid transporter), member 2 0.71667
MAST4 microtubule associated serine/threonine kinase family member 4 0.71667
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1 0.71667
AADAC arylacetamide deacetylase 0.71667
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa 0.71667
QSOX1 quiescin Q6 sulfhydryl oxidase 1 0.71667
MAP1LC3B microtubule-associated protein 1 light chain 3 beta 0.71667
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa 0.71667
MARC2 mitochondrial amidoxime reducing component 2 0.71667
FHAD1 forkhead-associated (FHA) phosphopeptide binding domain 1 0.705466
SNX10 sorting nexin 10 0.705466
CCDC53 coiled-coil domain containing 53 0.703024
KCNE4 potassium channel, voltage gated subfamily E regulatory beta subunit 4 0.703024
ZDHHC9 zinc finger, DHHC-type containing 9 0.701078
SLC25A47 solute carrier family 25, member 47 0.701078
FPGS folylpolyglutamate synthase 0.690415
HMGA2 high mobility group AT-hook 2 0.690415
GCKR glucokinase (hexokinase 4) regulator 0.657111
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.641527
C4B complement component 4B (Chido blood group) 0.618347
PFKFB1 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 0.618347
RBPMS RNA binding protein with multiple splicing 0.618347
MFSD11 major facilitator superfamily domain containing 11 0.618347
LAT linker for activation of T cells 0.618347
VKORC1 vitamin K epoxide reductase complex, subunit 1 0.618347
ABHD3 abhydrolase domain containing 3 0.618347
SPP1 secreted phosphoprotein 1 0.618347
MPC1 mitochondrial pyruvate carrier 1 0.618347
PCYT2 phosphate cytidylyltransferase 2, ethanolamine 0.618347
ASB13 ankyrin repeat and SOCS box containing 13 0.618347
SMIM5 small integral membrane protein 5 0.618347
TVP23B trans-golgi network vesicle protein 23 homolog B (S. cerevisiae) 0.618347
VTN vitronectin 0.618347
EVA1A eva-1 homolog A (C. elegans) 0.618347
ITIH1 inter-alpha-trypsin inhibitor heavy chain 1 0.618347
MOBP myelin-associated oligodendrocyte basic protein 0.612872
APCS amyloid P component, serum 0.611625
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.611625
ABCD2 ATP-binding cassette, sub-family D (ALD), member 2 0.596358
FAM73B family with sequence similarity 73, member B 0.596358
AHCY adenosylhomocysteinase 0.596358
L3HYPDH L-3-hydroxyproline dehydratase (trans-) 0.583619
EBP emopamil binding protein (sterol isomerase) 0.583619
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 0.583619
NLRP6 NLR family, pyrin domain containing 6 0.58352
GSTZ1 glutathione S-transferase zeta 1 0.58352
HDLBP high density lipoprotein binding protein 0.58352
HBP1 HMG-box transcription factor 1 0.582202
FGB fibrinogen beta chain 0.582202
FAM19A1 family with sequence similarity 19 (chemokine (C-C motif)-like), member A1 0.582202
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.582202
TMPRSS6 transmembrane protease, serine 6 0.577561
GHR growth hormone receptor 0.577561
FETUB fetuin B 0.577561
ABHD2 abhydrolase domain containing 2 0.577561
MPZL2 myelin protein zero-like 2 0.559477
FBXO42 F-box protein 42 0.559477
SPRYD4 SPRY domain containing 4 0.541274
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 0.541274
AQP9 aquaporin 9 0.541274
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 0.528901
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.528901
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) 0.528901
PKP2 plakophilin 2 0.528901
TGM2 transglutaminase 2 0.528901
APOH apolipoprotein H (beta-2-glycoprotein I) 0.528901
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 0.528901
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.519642
ALDH2 aldehyde dehydrogenase 2 family (mitochondrial) 0.503603
GALNS galactosamine (N-acetyl)-6-sulfatase 0.498073
RAB9A RAB9A, member RAS oncogene family 0.498073
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.483978
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.461908
REPIN1 replication initiator 1 0.450057
SLC25A42 solute carrier family 25, member 42 0.450057
LIN7B lin-7 homolog B (C. elegans) 0.450057
ZEB2 zinc finger E-box binding homeobox 2 0.444133
FAAH fatty acid amide hydrolase 0.441696
ADK adenosine kinase 0.440053
CNTN2 contactin 2 (axonal) 0.440053
FAM53B family with sequence similarity 53, member B 0.440053
DHRS4 dehydrogenase/reductase (SDR family) member 4 0.438918
EPAS1 endothelial PAS domain protein 1 0.437371
PDXK pyridoxal (pyridoxine, vitamin B6) kinase 0.431341
ZNF235 zinc finger protein 235 0.431341
CLINT1 clathrin interactor 1 0.431341
SLC20A2 solute carrier family 20 (phosphate transporter), member 2 0.431341
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2 0.431341
ZFYVE16 zinc finger, FYVE domain containing 16 0.419525
CBX1 chromobox homolog 1 0.419525
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.419525
LRRC40 leucine rich repeat containing 40 0.419525
SCO2 SCO2 cytochrome c oxidase assembly protein 0.408588
SLCO2A1 solute carrier organic anion transporter family, member 2A1 0.408588
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 0.404533
IDNK idnK, gluconokinase homolog (E. coli) 0.404533
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.403755
ENDOG endonuclease G 0.40287
DDT D-dopachrome tautomerase 0.40103
SERINC3 serine incorporator 3 0.381689
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial 0.378533
HAL histidine ammonia-lyase 0.374865
KIAA0040 KIAA0040 0.374865
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.374865
ADCY9 adenylate cyclase 9 0.367177
APOC1 apolipoprotein C-I 0.367177
FXR2 fragile X mental retardation, autosomal homolog 2 0.349382
PCED1A PC-esterase domain containing 1A 0.349382
C1QL2 complement component 1, q subcomponent-like 2 0.349157
MOCS2 molybdenum cofactor synthesis 2 0.347908
RPUSD3 RNA pseudouridylate synthase domain containing 3 0.347908
SDHA succinate dehydrogenase complex, subunit A, flavoprotein (Fp) 0.347908
LPGAT1 lysophosphatidylglycerol acyltransferase 1 0.347908
MACROD1 MACRO domain containing 1 0.347908
BIRC5 baculoviral IAP repeat containing 5 0.346575
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.346575
CNN3 calponin 3, acidic 0.346575
CYP4V2 cytochrome P450, family 4, subfamily V, polypeptide 2 0.346575
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip) 0.344938
ALDH7A1 aldehyde dehydrogenase 7 family, member A1 0.344938
TMEM176B transmembrane protein 176B 0.344938
PPP6R2 protein phosphatase 6, regulatory subunit 2 0.342924
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.339458
PCCA propionyl CoA carboxylase, alpha polypeptide 0.339458
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.339458
CLUH clustered mitochondria (cluA/CLU1) homolog 0.339458
PRODH2 proline dehydrogenase (oxidase) 2 0.335412
BTG1 B-cell translocation gene 1, anti-proliferative 0.334312
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.322782
REEP6 receptor accessory protein 6 0.322336
DENND5B DENN/MADD domain containing 5B 0.312037
GINM1 glycoprotein integral membrane 1 0.312037
SARM1 sterile alpha and TIR motif containing 1 0.312037
STAU2 staufen double-stranded RNA binding protein 2 0.312037
HIBADH 3-hydroxyisobutyrate dehydrogenase 0.312037
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 0.312037
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae) 0.312037
BCL2A1 BCL2-related protein A1 0.29821
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.294688
AHR aryl hydrocarbon receptor 0.29342
ALDH8A1 aldehyde dehydrogenase 8 family, member A1 0.29342
MMP8 matrix metallopeptidase 8 0.286526
NFE2L3 nuclear factor, erythroid 2-like 3 0.282943
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.282943
ATF5 activating transcription factor 5 0.282943
SAMM50 SAMM50 sorting and assembly machinery component 0.277269
SLC23A1 solute carrier family 23 (ascorbic acid transporter), member 1 0.273967
ADHFE1 alcohol dehydrogenase, iron containing, 1 0.273967
FGG fibrinogen gamma chain 0.27133
ACBD3 acyl-CoA binding domain containing 3 0.270929
HRSP12 heat-responsive protein 12 0.268519
CBR1 carbonyl reductase 1 0.268519
PHB prohibitin 0.268519
IL17RB interleukin 17 receptor B 0.261563
F5 coagulation factor V (proaccelerin, labile factor) 0.258396
MARC1 mitochondrial amidoxime reducing component 1 0.256548
DEPDC7 DEP domain containing 7 0.241427
PDXDC1 pyridoxal-dependent decarboxylase domain containing 1 0.237968
SCN8A sodium channel, voltage gated, type VIII alpha subunit 0.234497
MYO1C myosin IC 0.230861
CERS2 ceramide synthase 2 0.214492
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 0.184588
CCDC137 coiled-coil domain containing 137 0.16804
CD320 CD320 molecule 0.157841
UROC1 urocanate hydratase 1 0.15372
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB 0.149797
GLB1L2 galactosidase, beta 1-like 2 0.145035
ALG14 ALG14, UDP-N-acetylglucosaminyltransferase subunit 0.145035
PQLC1 PQ loop repeat containing 1 0.145035
QPRT quinolinate phosphoribosyltransferase 0.145035
GGT1 gamma-glutamyltransferase 1 0.145035
GAMT guanidinoacetate N-methyltransferase 0.145035
C1GALT1C1 C1GALT1-specific chaperone 1 0.145035
METTL3 methyltransferase like 3 0.133806
ABHD14B abhydrolase domain containing 14B 0.130509
MYO10 myosin X 0.130242
KRTAP5-3 keratin associated protein 5-3 0.12545
NDUFS3 NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) 0.124623
FUT7 fucosyltransferase 7 (alpha (1,3) fucosyltransferase) 0.124623
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) 0.123813
ABHD1 abhydrolase domain containing 1 0.121691
SRA1 steroid receptor RNA activator 1 0.11714
MARVELD2 MARVEL domain containing 2 0.11714
PLEC plectin 0.11714
RRP7A ribosomal RNA processing 7 homolog A (S. cerevisiae) 0.11714
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.114634
ETFA electron-transfer-flavoprotein, alpha polypeptide 0.098825
ESRP2 epithelial splicing regulatory protein 2 0.096467
CHADL chondroadherin-like 0.096467
SEC16A SEC16 homolog A (S. cerevisiae) 0.096467
STK32C serine/threonine kinase 32C 0.096467
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.096467
TICAM1 toll-like receptor adaptor molecule 1 0.096467
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2 0.096467
GRTP1 growth hormone regulated TBC protein 1 0.083289
TMPRSS2 transmembrane protease, serine 2 0.074042
SIRT3 sirtuin 3 0.066301
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.065995
PPP2R5B protein phosphatase 2, regulatory subunit B', beta 0.065995
MDH1 malate dehydrogenase 1, NAD (soluble) 0.051354
ATP8A2 ATPase, aminophospholipid transporter, class I, type 8A, member 2 0.045626
RNF13 ring finger protein 13 0.044553
ANGPTL1 angiopoietin-like 1 0.044553
SH3GL2 SH3-domain GRB2-like 2 0.044553
YIF1A Yip1 interacting factor homolog A (S. cerevisiae) 0.044553
YIPF7 Yip1 domain family, member 7 0.0418
FAM134B family with sequence similarity 134, member B 0.0418
STXBP6 syntaxin binding protein 6 (amisyn) 0.0418
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) 0.041186
AKAP9 A kinase (PRKA) anchor protein 9 0.041186
GCAT glycine C-acetyltransferase 0.041186
SCARA5 scavenger receptor class A, member 5 0.03156
ACSS1 acyl-CoA synthetase short-chain family member 1 0.03156
ST3GAL1 ST3 beta-galactoside alpha-2,3-sialyltransferase 1 0.03156
DESI2 desumoylating isopeptidase 2 0.03156
GPX3 glutathione peroxidase 3 0.03156
NRDE2 NRDE-2, necessary for RNA interference, domain containing 0.03156
APOC4 apolipoprotein C-IV 0.03156
ACOX1 acyl-CoA oxidase 1, palmitoyl 0.018928
CPLX1 complexin 1 0.018928
AGXT alanine-glyoxylate aminotransferase 0.015554
ELOVL2 ELOVL fatty acid elongase 2 0.015554
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.015554
R3HDM1 R3H domain containing 1 0.015554
MMD2 monocyte to macrophage differentiation-associated 2 0.015554
UGP2 UDP-glucose pyrophosphorylase 2 0.015554
MOV10 Mov10 RISC complex RNA helicase 0.015554
PLIN4 perilipin 4 0.013222
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 0.013222
GRIK5 glutamate receptor, ionotropic, kainate 5 0.011894

decreased expression

Symbol Name Standardized Value
WBP1L WW domain binding protein 1-like -0.370604
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1 -0.370207
LRRK1 leucine-rich repeat kinase 1 -0.370207
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 -0.370207
TYSND1 trypsin domain containing 1 -0.369993
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 -0.369993
TMED7 transmembrane emp24 protein transport domain containing 7 -0.369993
MESP2 mesoderm posterior basic helix-loop-helix transcription factor 2 -0.369993
ARHGAP39 Rho GTPase activating protein 39 -0.369993
TSTD3 thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 -0.368903
SATB1 SATB homeobox 1 -0.368363
SIAH2 siah E3 ubiquitin protein ligase 2 -0.367412
BTBD19 BTB (POZ) domain containing 19 -0.367412
COL23A1 collagen, type XXIII, alpha 1 -0.367412
C1R complement component 1, r subcomponent -0.366984
NIT2 nitrilase family, member 2 -0.366984
PTPRN protein tyrosine phosphatase, receptor type, N -0.366984
CPQ carboxypeptidase Q -0.366941
SAA4 serum amyloid A4, constitutive -0.366713
PDE10A phosphodiesterase 10A -0.36634
SLC25A33 solute carrier family 25 (pyrimidine nucleotide carrier), member 33 -0.366186
MXD4 MAX dimerization protein 4 -0.365407
SPTSSB serine palmitoyltransferase, small subunit B -0.365407
FBXW2 F-box and WD repeat domain containing 2 -0.365223
RBBP8 retinoblastoma binding protein 8 -0.365223
RNF2 ring finger protein 2 -0.365223
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.365223
HOGA1 4-hydroxy-2-oxoglutarate aldolase 1 -0.365223
PAWR PRKC, apoptosis, WT1, regulator -0.364536
CCNYL1 cyclin Y-like 1 -0.363811
LINGO1 leucine rich repeat and Ig domain containing 1 -0.363436
UBXN10 UBX domain protein 10 -0.363436
TREML2 triggering receptor expressed on myeloid cells-like 2 -0.363033
NEGR1 neuronal growth regulator 1 -0.362201
AVPR1A arginine vasopressin receptor 1A -0.362201
SSB Sjogren syndrome antigen B (autoantigen La) -0.361338
TSPAN2 tetraspanin 2 -0.361107
PALMD palmdelphin -0.361107
ECI2 enoyl-CoA delta isomerase 2 -0.358191
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 -0.356872
NDUFB9 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 9, 22kDa -0.352918
HSPBP1 HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 -0.352918
HYKK hydroxylysine kinase -0.352918
FOXM1 forkhead box M1 -0.352918
KPTN kaptin (actin binding protein) -0.351808
CTH cystathionine gamma-lyase -0.351779
EGFR epidermal growth factor receptor -0.351691
ARHGEF28 Rho guanine nucleotide exchange factor (GEF) 28 -0.351161
C10ORF11 chromosome 10 open reading frame 11 -0.350984
INSIG2 insulin induced gene 2 -0.350984
NSMCE1 non-SMC element 1 homolog (S. cerevisiae) -0.350333
C2ORF72 chromosome 2 open reading frame 72 -0.349574
UBA2 ubiquitin-like modifier activating enzyme 2 -0.348497
TMEM129 transmembrane protein 129, E3 ubiquitin protein ligase -0.348497
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8 -0.34764
IGFBP4 insulin-like growth factor binding protein 4 -0.34764
DRAM2 DNA-damage regulated autophagy modulator 2 -0.34764
CRK v-crk avian sarcoma virus CT10 oncogene homolog -0.34764
RAC2 ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) -0.34764
FKBP5 FK506 binding protein 5 -0.346158
FAM117B family with sequence similarity 117, member B -0.346158
AFM afamin -0.34552
SDCBP2 syndecan binding protein (syntenin) 2 -0.34552
NINJ2 ninjurin 2 -0.345078
LENG9 leukocyte receptor cluster (LRC) member 9 -0.343811
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast) -0.343382
CCDC91 coiled-coil domain containing 91 -0.341526
ESRRG estrogen-related receptor gamma -0.341526
C9ORF3 chromosome 9 open reading frame 3 -0.341249
SLC13A4 solute carrier family 13 (sodium/sulfate symporter), member 4 -0.340264
FITM2 fat storage-inducing transmembrane protein 2 -0.338351
C12ORF73 chromosome 12 open reading frame 73 -0.337795
PCCB propionyl CoA carboxylase, beta polypeptide -0.33271
NAT10 N-acetyltransferase 10 (GCN5-related) -0.33271
PTN pleiotrophin -0.331273
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.33081
CLTC clathrin, heavy chain (Hc) -0.33081
GALE UDP-galactose-4-epimerase -0.33081
PMEL premelanosome protein -0.33081
SYT13 synaptotagmin XIII -0.33081
CXCL14 chemokine (C-X-C motif) ligand 14 -0.330038
SZRD1 SUZ RNA binding domain containing 1 -0.330038
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha -0.329791
ECHDC2 enoyl CoA hydratase domain containing 2 -0.329035
TMEM33 transmembrane protein 33 -0.326169
KIF15 kinesin family member 15 -0.325215
ASPA aspartoacylase -0.325215
NR4A3 nuclear receptor subfamily 4, group A, member 3 -0.323171
PCOLCE procollagen C-endopeptidase enhancer -0.323171
FAM167B family with sequence similarity 167, member B -0.323171
COL5A3 collagen, type V, alpha 3 -0.320304
BCAR1 breast cancer anti-estrogen resistance 1 -0.317934
GSKIP GSK3B interacting protein -0.316957
PPP2R2D protein phosphatase 2, regulatory subunit B, delta -0.316957
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5 -0.316957
TMBIM4 transmembrane BAX inhibitor motif containing 4 -0.312844
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 -0.312814
SPG20 spastic paraplegia 20 (Troyer syndrome) -0.312814
ISLR immunoglobulin superfamily containing leucine-rich repeat -0.312799
FBXO24 F-box protein 24 -0.311386
PDLIM5 PDZ and LIM domain 5 -0.309202
CEP70 centrosomal protein 70kDa -0.309202
CD86 CD86 molecule -0.308263
LEPROTL1 leptin receptor overlapping transcript-like 1 -0.307733
KLK6 kallikrein-related peptidase 6 -0.307597
NRL neural retina leucine zipper -0.307279
VAV2 vav 2 guanine nucleotide exchange factor -0.306267
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.306267
AGPS alkylglycerone phosphate synthase -0.305723
ASF1A anti-silencing function 1A histone chaperone -0.304365
RPP21 ribonuclease P/MRP 21kDa subunit -0.301744
CXXC4 CXXC finger protein 4 -0.298919
BAMBI BMP and activin membrane-bound inhibitor -0.298919
CTSH cathepsin H -0.298904
DTNA dystrobrevin, alpha -0.298904
RHOBTB1 Rho-related BTB domain containing 1 -0.298904
ANKRD46 ankyrin repeat domain 46 -0.295011
GNG12 guanine nucleotide binding protein (G protein), gamma 12 -0.295011
IGFBP1 insulin-like growth factor binding protein 1 -0.294951
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) -0.294578
SGCB sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) -0.294578
PLIN5 perilipin 5 -0.294578
ABCA6 ATP-binding cassette, sub-family A (ABC1), member 6 -0.292831
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.291326
SOCS2 suppressor of cytokine signaling 2 -0.286927
SSR1 signal sequence receptor, alpha -0.286023
PLCXD2 phosphatidylinositol-specific phospholipase C, X domain containing 2 -0.284543
MAOB monoamine oxidase B -0.284543
TTC39C tetratricopeptide repeat domain 39C -0.282503
SERPINA11 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11 -0.282503
LRG1 leucine-rich alpha-2-glycoprotein 1 -0.281647
JMJD4 jumonji domain containing 4 -0.281382
POGK pogo transposable element with KRAB domain -0.281382
FAS Fas cell surface death receptor -0.281382
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 -0.281382
GRB14 growth factor receptor-bound protein 14 -0.279422
POR P450 (cytochrome) oxidoreductase -0.275835
KLKB1 kallikrein B, plasma (Fletcher factor) 1 -0.275306
EXOG endo/exonuclease (5'-3'), endonuclease G-like -0.275306
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein -0.275306
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 -0.275306
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.273987
PCNX pecanex homolog (Drosophila) -0.273752
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase -0.272844
NT5E 5'-nucleotidase, ecto (CD73) -0.272844
TAGLN2 transgelin 2 -0.272654
CES1 carboxylesterase 1 -0.272654
SLC22A18 solute carrier family 22, member 18 -0.272654
SLAIN2 SLAIN motif family, member 2 -0.271088
WNT8A wingless-type MMTV integration site family, member 8A -0.269934
KCTD1 potassium channel tetramerization domain containing 1 -0.268561
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase -0.267962
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.267612
TMEM176A transmembrane protein 176A -0.264624
SERINC2 serine incorporator 2 -0.264624
OSTF1 osteoclast stimulating factor 1 -0.264624
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) -0.260118
CFHR2 complement factor H-related 2 -0.259958
EIF2AK1 eukaryotic translation initiation factor 2-alpha kinase 1 -0.256232
GSTM1 glutathione S-transferase mu 1 -0.256232
SULT1D1P sulfotransferase family, cytosolic, 1D, member 1, pseudogene -0.254307
RNF141 ring finger protein 141 -0.252775
FEM1C fem-1 homolog c (C. elegans) -0.252197
SOCS1 suppressor of cytokine signaling 1 -0.251851
RAB7A RAB7A, member RAS oncogene family -0.251071
SOX5 SRY (sex determining region Y)-box 5 -0.250941
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.250941
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B) -0.250941
CPT1B carnitine palmitoyltransferase 1B (muscle) -0.250941
SUCLG1 succinate-CoA ligase, alpha subunit -0.250941
CLDN15 claudin 15 -0.250941
ACTL6A actin-like 6A -0.250941
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.248491
F11 coagulation factor XI -0.247498
FMO5 flavin containing monooxygenase 5 -0.247498
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.247498
CYP26B1 cytochrome P450, family 26, subfamily B, polypeptide 1 -0.246434
PDGFC platelet derived growth factor C -0.246434
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3 -0.246434
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.246434
TMED4 transmembrane emp24 protein transport domain containing 4 -0.245629
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.245629
RTP3 receptor (chemosensory) transporter protein 3 -0.245629
DLK1 delta-like 1 homolog (Drosophila) -0.244596
TOR3A torsin family 3, member A -0.241301
MRPL39 mitochondrial ribosomal protein L39 -0.241301
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -0.239614
ATP7B ATPase, Cu++ transporting, beta polypeptide -0.239043
CREB3L3 cAMP responsive element binding protein 3-like 3 -0.238815
OSBPL1A oxysterol binding protein-like 1A -0.238202
MTSS1 metastasis suppressor 1 -0.238202
COPS5 COP9 signalosome subunit 5 -0.237874
CSAD cysteine sulfinic acid decarboxylase -0.234275
PTTG1IP pituitary tumor-transforming 1 interacting protein -0.234275
AAED1 AhpC/TSA antioxidant enzyme domain containing 1 -0.234275
SLC2A2 solute carrier family 2 (facilitated glucose transporter), member 2 -0.234275
METTL15 methyltransferase like 15 -0.234275
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase -0.234275
COQ9 coenzyme Q9 -0.232956
DLEU2 deleted in lymphocytic leukemia 2 (non-protein coding) -0.232956
ENOPH1 enolase-phosphatase 1 -0.23195
MPV17 MpV17 mitochondrial inner membrane protein -0.228995
MRPL43 mitochondrial ribosomal protein L43 -0.227387
GRPEL2 GrpE-like 2, mitochondrial (E. coli) -0.227387
PTMS parathymosin -0.227387
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 -0.227387
PLIN3 perilipin 3 -0.227387
MIIP migration and invasion inhibitory protein -0.227387
RAB27B RAB27B, member RAS oncogene family -0.227387
RBPJL recombination signal binding protein for immunoglobulin kappa J region-like -0.226598
KDM2A lysine (K)-specific demethylase 2A -0.226598
CROT carnitine O-octanoyltransferase -0.226598
FAM101B family with sequence similarity 101, member B -0.225712
CEP295 centrosomal protein 295kDa -0.225712
ARHGAP31 Rho GTPase activating protein 31 -0.225332
ACADL acyl-CoA dehydrogenase, long chain -0.222257
TLCD2 TLC domain containing 2 -0.222257
RGN regucalcin -0.221585
TF transferrin -0.220199
SPP2 secreted phosphoprotein 2, 24kDa -0.216456
LSR lipolysis stimulated lipoprotein receptor -0.211976
TMEM64 transmembrane protein 64 -0.210312
ZFP36L2 ZFP36 ring finger protein-like 2 -0.207197
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.207197
SLC17A2 solute carrier family 17, member 2 -0.207183
GULOP gulonolactone (L-) oxidase, pseudogene -0.206506
ERCC2 excision repair cross-complementation group 2 -0.206506
APOE apolipoprotein E -0.206465
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 -0.205485
VSIG2 V-set and immunoglobulin domain containing 2 -0.20394
TCEAL1 transcription elongation factor A (SII)-like 1 -0.20394
LRP2BP LRP2 binding protein -0.20394
TUBB6 tubulin, beta 6 class V -0.203789
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22 -0.203651
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 -0.203651
UBA7 ubiquitin-like modifier activating enzyme 7 -0.202742
GOT1L1 glutamic-oxaloacetic transaminase 1-like 1 -0.202659
DAW1 dynein assembly factor with WDR repeat domains 1 -0.202659
CLEC7A C-type lectin domain family 7, member A -0.202659
TM9SF4 transmembrane 9 superfamily protein member 4 -0.202659
ALKBH1 alkB, alkylation repair homolog 1 (E. coli) -0.202659
DSC2 desmocollin 2 -0.202659
TXN2 thioredoxin 2 -0.202123
ADAMTSL1 ADAMTS-like 1 -0.202123
GCM1 glial cells missing homolog 1 (Drosophila) -0.197484
ACAA1 acetyl-CoA acyltransferase 1 -0.194187
CCDC93 coiled-coil domain containing 93 -0.193368
ADA adenosine deaminase -0.190709
COMT catechol-O-methyltransferase -0.189946
RMDN2 regulator of microtubule dynamics 2 -0.189428
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 -0.187619
AQP11 aquaporin 11 -0.185892
CAPN10 calpain 10 -0.185892
ARMC2 armadillo repeat containing 2 -0.182171
PIAS3 protein inhibitor of activated STAT, 3 -0.182076
HADH hydroxyacyl-CoA dehydrogenase -0.18175
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide -0.18175
GLB1 galactosidase, beta 1 -0.180963
KLF16 Kruppel-like factor 16 -0.179566
MKKS McKusick-Kaufman syndrome -0.178914
TSKU tsukushi, small leucine rich proteoglycan -0.177775
DNASE2 deoxyribonuclease II, lysosomal -0.177504
MAGED1 melanoma antigen family D1 -0.176568
PDZK1IP1 PDZK1 interacting protein 1 -0.175889
CAT catalase -0.175631
FNDC5 fibronectin type III domain containing 5 -0.172904
AP3B1 adaptor-related protein complex 3, beta 1 subunit -0.172321
NEK11 NIMA-related kinase 11 -0.172321
MUT methylmalonyl CoA mutase -0.172321
IGFLR1 IGF-like family receptor 1 -0.172321
FAM213A family with sequence similarity 213, member A -0.172321
RNF151 ring finger protein 151 -0.172321
MPP1 membrane protein, palmitoylated 1, 55kDa -0.172321
CSN1S2AP casein alpha s2-like A, pseudogene -0.172104
TXNRD2 thioredoxin reductase 2 -0.170476
A2M alpha-2-macroglobulin -0.170476
SFRP2 secreted frizzled-related protein 2 -0.170476
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.170476
LAMA1 laminin, alpha 1 -0.170476
MEGF6 multiple EGF-like-domains 6 -0.169295
LGALSL lectin, galactoside-binding-like -0.165441
CTR9 CTR9, Paf1/RNA polymerase II complex component -0.163365
MEG8 maternally expressed 8 (non-protein coding) -0.15641
FAM136A family with sequence similarity 136, member A -0.15488
ACOT4 acyl-CoA thioesterase 4 -0.153662
MMD monocyte to macrophage differentiation-associated -0.151608
ICA1L islet cell autoantigen 1,69kDa-like -0.150852
TMEM30A transmembrane protein 30A -0.149233
DACT3 dishevelled-binding antagonist of beta-catenin 3 -0.149044
SP5 Sp5 transcription factor -0.146754
RBKS ribokinase -0.146284
KHDC3L KH domain containing 3-like, subcortical maternal complex member -0.14506
SEMA5B sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B -0.142428
ANKRD28 ankyrin repeat domain 28 -0.142428
CDK5 cyclin-dependent kinase 5 -0.142401
SMC4 structural maintenance of chromosomes 4 -0.142401
FUOM fucose mutarotase -0.142401
SH3BGR SH3 domain binding glutamate-rich protein -0.141542
UMOD uromodulin -0.14106
PDLIM1 PDZ and LIM domain 1 -0.14106
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.140215
ACACB acetyl-CoA carboxylase beta -0.140215
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.140215
HELZ helicase with zinc finger -0.140215
NANOS1 nanos homolog 1 (Drosophila) -0.13992
MAFK v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K -0.13992
SLC26A1 solute carrier family 26 (anion exchanger), member 1 -0.139732
PITPNM3 PITPNM family member 3 -0.139464
ZDHHC14 zinc finger, DHHC-type containing 14 -0.139464
MAP4K1 mitogen-activated protein kinase kinase kinase kinase 1 -0.139223
TMEM70 transmembrane protein 70 -0.139223
NIPAL1 NIPA-like domain containing 1 -0.138553
CDIP1 cell death-inducing p53 target 1 -0.138553
APOA1BP apolipoprotein A-I binding protein -0.138553
OPTN optineurin -0.138553
FDX1 ferredoxin 1 -0.138553
C9ORF91 chromosome 9 open reading frame 91 -0.138553
SBK1 SH3 domain binding kinase 1 -0.136139
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2 -0.136046
KDM5C lysine (K)-specific demethylase 5C -0.136046
TEX2 testis expressed 2 -0.136046
EIF1AX eukaryotic translation initiation factor 1A, X-linked -0.123292
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -0.118982
OAF OAF homolog (Drosophila) -0.117901
HSD17B12 hydroxysteroid (17-beta) dehydrogenase 12 -0.116279
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3 -0.116279
RTN4 reticulon 4 -0.115827
APOC2 apolipoprotein C-II -0.115827
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 -0.115483
POLG polymerase (DNA directed), gamma -0.115483
ZWINT ZW10 interacting kinetochore protein -0.115483
PEX14 peroxisomal biogenesis factor 14 -0.115483
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 -0.111971
SYT1 synaptotagmin I -0.110858
ZCCHC10 zinc finger, CCHC domain containing 10 -0.108141
RGS16 regulator of G-protein signaling 16 -0.108141
TMEM38B transmembrane protein 38B -0.107452
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 -0.104638
PAPL iron/zinc purple acid phosphatase-like protein -0.104638
ZNF775 zinc finger protein 775 -0.104306
SYNPO2L synaptopodin 2-like -0.104306
CHEK1 checkpoint kinase 1 -0.104111
FGD5 FYVE, RhoGEF and PH domain containing 5 -0.102465
RHPN2 rhophilin, Rho GTPase binding protein 2 -0.102363
GPR132 G protein-coupled receptor 132 -0.102199
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 -0.101974
MID2 midline 2 -0.099892
ENTPD8 ectonucleoside triphosphate diphosphohydrolase 8 -0.0994
UNC119 unc-119 homolog (C. elegans) -0.0994
OS9 osteosarcoma amplified 9, endoplasmic reticulum lectin -0.0994
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 -0.096733
ZNF112 zinc finger protein 112 -0.096733
SOX10 SRY (sex determining region Y)-box 10 -0.095726
ECHS1 enoyl CoA hydratase, short chain, 1, mitochondrial -0.0925
PUS1 pseudouridylate synthase 1 -0.0925
SFXN2 sideroflexin 2 -0.091732
NGEF neuronal guanine nucleotide exchange factor -0.091732
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like -0.091732
PLG plasminogen -0.091732
COX8A cytochrome c oxidase subunit VIIIA (ubiquitous) -0.091732
CLDN12 claudin 12 -0.091732
RAB14 RAB14, member RAS oncogene family -0.091163
GSTO1 glutathione S-transferase omega 1 -0.088991
CEBPG CCAAT/enhancer binding protein (C/EBP), gamma -0.088991
ZBTB16 zinc finger and BTB domain containing 16 -0.085576
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha -0.085576
TANGO2 transport and golgi organization 2 homolog (Drosophila) -0.083855
ATP5G1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9) -0.083374
HOOK2 hook microtubule-tethering protein 2 -0.083374
RORA RAR-related orphan receptor A -0.083374
ZYG11B zyg-11 family member B, cell cycle regulator -0.08246
FAM195A family with sequence similarity 195, member A -0.08226
HAO1 hydroxyacid oxidase (glycolate oxidase) 1 -0.081359
CTSO cathepsin O -0.081214
PARP6 poly (ADP-ribose) polymerase family, member 6 -0.081214
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 -0.081214
GORAB golgin, RAB6-interacting -0.081214
EVC Ellis van Creveld protein -0.081214
ZNF14 zinc finger protein 14 -0.081214
PIGX phosphatidylinositol glycan anchor biosynthesis, class X -0.081214
CMTM8 CKLF-like MARVEL transmembrane domain containing 8 -0.081214
SEC16B SEC16 homolog B (S. cerevisiae) -0.081214
AANAT aralkylamine N-acetyltransferase -0.081214
BABAM1 BRISC and BRCA1 A complex member 1 -0.081214
SLC39A5 solute carrier family 39 (zinc transporter), member 5 -0.078326
TSPAN31 tetraspanin 31 -0.077929
TRPC2 transient receptor potential cation channel, subfamily C, member 2, pseudogene -0.071495
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 -0.071495
SGCE sarcoglycan, epsilon -0.070532
PPA1 pyrophosphatase (inorganic) 1 -0.070532
AASS aminoadipate-semialdehyde synthase -0.068552
HLA-A major histocompatibility complex, class I, A -0.068552
ANGPTL6 angiopoietin-like 6 -0.065032
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1 -0.062586
SPATS1 spermatogenesis associated, serine-rich 1 -0.061689
CCDC88C coiled-coil domain containing 88C -0.061689
UOX urate oxidase, pseudogene -0.061689
BEX1 brain expressed, X-linked 1 -0.057426
QDPR quinoid dihydropteridine reductase -0.055509
PSEN2 presenilin 2 -0.051633
IQCA1 IQ motif containing with AAA domain 1 -0.049597
AVIL advillin -0.049597
LBP lipopolysaccharide binding protein -0.049597
ACVR2B activin A receptor, type IIB -0.049597
ACAA2 acetyl-CoA acyltransferase 2 -0.049597
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 -0.0471
MIA2 melanoma inhibitory activity 2 -0.042734
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -0.039852
STON1 stonin 1 -0.039852
COL18A1 collagen, type XVIII, alpha 1 -0.039852
HSD17B7 hydroxysteroid (17-beta) dehydrogenase 7 -0.039852
RBP1 retinol binding protein 1, cellular -0.036467
PYGL phosphorylase, glycogen, liver -0.036467
TAOK1 TAO kinase 1 -0.036341
EPS8L1 EPS8-like 1 -0.035543
ADCK3 aarF domain containing kinase 3 -0.035543
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) -0.035543
MRPL48 mitochondrial ribosomal protein L48 -0.035543
PRR5L proline rich 5 like -0.035543
IL1RAP interleukin 1 receptor accessory protein -0.035543
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) -0.035543
BAIAP2 BAI1-associated protein 2 -0.028955
GLS2 glutaminase 2 (liver, mitochondrial) -0.020765
FGF1 fibroblast growth factor 1 (acidic) -0.016754
SPG7 spastic paraplegia 7 (pure and complicated autosomal recessive) -0.016754
PARM1 prostate androgen-regulated mucin-like protein 1 -0.016754
SEC23A Sec23 homolog A (S. cerevisiae) -0.014646
HDHD3 haloacid dehalogenase-like hydrolase domain containing 3 -0.013027
TMEM135 transmembrane protein 135 -0.013027
AMY2B amylase, alpha 2B (pancreatic) -0.011897
ZNRF4 zinc and ring finger 4 -0.011897
BSND barttin CLCNK-type chloride channel accessory beta subunit -0.011897
FN1 fibronectin 1 -0.011897
Funding