holliday junction resolvase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A protein complex that mediates the conversion of a Holliday junction into two separate duplex DNA molecules; the complex includes a single- or multisubunit helicase that catalyzes the extension of heteroduplex DNA by branch migration and a nuclease that resolves the junction by nucleolytic cleavage. (Gene Ontology, GO_0048476)
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45 proteins co-occuring with the holliday junction resolvase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
MUS81 MUS81 structure-specific endonuclease subunit 2.76424
SLX4 SLX4 structure-specific endonuclease subunit 2.27131
EME2 essential meiotic structure-specific endonuclease subunit 2 2.24056
EME1 essential meiotic structure-specific endonuclease 1 2.0685
GEN1 GEN1 Holliday junction 5' flap endonuclease 2.00908
ERCC4 excision repair cross-complementation group 4 1.7682
RMI2 RecQ mediated genome instability 2 1.43387
SLX4IP SLX4 interacting protein 1.2996
GPR148 G protein-coupled receptor 148 1.28836
FAN1 FANCD2/FANCI-associated nuclease 1 1.19108
RMI1 RecQ mediated genome instability 1 1.15774
DCLRE1A DNA cross-link repair 1A 0.986342
TERF2IP telomeric repeat binding factor 2, interacting protein 0.964069
ERCC1 excision repair cross-complementation group 1 0.882399
RAD54L RAD54-like (S. cerevisiae) 0.871806
FANCD2 Fanconi anemia, complementation group D2 0.840105
RAD52 RAD52 homolog (S. cerevisiae) 0.814864
FANCM Fanconi anemia, complementation group M 0.766804
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.763617
WEE1 WEE1 G2 checkpoint kinase 0.714126
VPRBP Vpr (HIV-1) binding protein 0.712351
STRA13 stimulated by retinoic acid 13 0.679849
C19ORF40 chromosome 19 open reading frame 40 0.675065
UBA2 ubiquitin-like modifier activating enzyme 2 0.614589
RAD51C RAD51 paralog C 0.521023
PLK1 polo-like kinase 1 0.51694
TERF2 telomeric repeat binding factor 2 0.493371
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.490944
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.474018
APOLD1 apolipoprotein L domain containing 1 0.458404
FANCI Fanconi anemia, complementation group I 0.434196
BLM Bloom syndrome, RecQ helicase-like 0.432224
H2AFX H2A histone family, member X 0.421604
UBE2N ubiquitin-conjugating enzyme E2N 0.371599
POLL polymerase (DNA directed), lambda 0.365477
ATM ATM serine/threonine kinase 0.336996
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) 0.32195
FANCA Fanconi anemia, complementation group A 0.304399
DDB1 damage-specific DNA binding protein 1, 127kDa 0.288091
EXO1 exonuclease 1 0.286245
APITD1 apoptosis-inducing, TAF9-like domain 1 0.283295
FEN1 flap structure-specific endonuclease 1 0.2719
TOP1 topoisomerase (DNA) I 0.260566
CDK1 cyclin-dependent kinase 1 0.216111
SRSF1 serine/arginine-rich splicing factor 1 0.177439