homatropine-1806 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the homatropine-1806 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAAS achalasia, adrenocortical insufficiency, alacrimia
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
APOL6 apolipoprotein L, 6
ARFIP1 ADP-ribosylation factor interacting protein 1
ARNTL aryl hydrocarbon receptor nuclear translocator-like
ASPH aspartate beta-hydroxylase
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
ATP10D ATPase, class V, type 10D
BCL2L1 BCL2-like 1
BLVRA biliverdin reductase A
CASP8 caspase 8, apoptosis-related cysteine peptidase
CDC73 cell division cycle 73
CPD carboxypeptidase D
CTNND2 catenin (cadherin-associated protein), delta 2
DBT dihydrolipoamide branched chain transacylase E2
DEDD death effector domain containing
DHODH dihydroorotate dehydrogenase (quinone)
EGFR epidermal growth factor receptor
EPB41L2 erythrocyte membrane protein band 4.1-like 2
F2RL1 coagulation factor II (thrombin) receptor-like 1
FCF1 FCF1 rRNA-processing protein
FH fumarate hydratase
FLOT1 flotillin 1
GK glycerol kinase
GSTM4 glutathione S-transferase mu 4
HMOX2 heme oxygenase 2
HOOK1 hook microtubule-tethering protein 1
HP1BP3 heterochromatin protein 1, binding protein 3
HSPA4 heat shock 70kDa protein 4
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IL1RAP interleukin 1 receptor accessory protein
INO80B INO80 complex subunit B
ITGA6 integrin, alpha 6
JAK2 Janus kinase 2
KCTD20 potassium channel tetramerization domain containing 20
KDM6A lysine (K)-specific demethylase 6A
KIAA1549L KIAA1549-like
KIDINS220 kinase D-interacting substrate, 220kDa
KLHL9 kelch-like family member 9
KRT33A keratin 33A, type I
LMAN1 lectin, mannose-binding, 1
LRRC61 leucine rich repeat containing 61
LYPD3 LY6/PLAUR domain containing 3
MAP3K9 mitogen-activated protein kinase kinase kinase 9
MAPK14 mitogen-activated protein kinase 14
MAT2A methionine adenosyltransferase II, alpha
MCM4 minichromosome maintenance complex component 4
MED12 mediator complex subunit 12
MEF2D myocyte enhancer factor 2D
MET MET proto-oncogene, receptor tyrosine kinase
MFN1 mitofusin 1
MVK mevalonate kinase
NADK NAD kinase
NAT6 N-acetyltransferase 6 (GCN5-related)
NEK2 NIMA-related kinase 2
NNT nicotinamide nucleotide transhydrogenase
NPAS2 neuronal PAS domain protein 2
NPEPL1 aminopeptidase-like 1
NR2F6 nuclear receptor subfamily 2, group F, member 6
OAZ3 ornithine decarboxylase antizyme 3
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAPOLA poly(A) polymerase alpha
PGAP1 post-GPI attachment to proteins 1
PLAGL2 pleiomorphic adenoma gene-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PSAT1 phosphoserine aminotransferase 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RAB6A RAB6A, member RAS oncogene family
RAD51D RAD51 paralog D
RBL2 retinoblastoma-like 2
RDX radixin
RHOBTB3 Rho-related BTB domain containing 3
RPL13P5 ribosomal protein L13 pseudogene 5
SFTPB surfactant protein B
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
SMC1A structural maintenance of chromosomes 1A
SOS2 son of sevenless homolog 2 (Drosophila)
SP140L SP140 nuclear body protein-like
SRPK1 SRSF protein kinase 1
SRPR signal recognition particle receptor (docking protein)
STK17A serine/threonine kinase 17a
SYNJ2 synaptojanin 2
TAF13 TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TMED2 transmembrane emp24 domain trafficking protein 2
TMEM63A transmembrane protein 63A
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TOR1AIP1 torsin A interacting protein 1
TREX1 three prime repair exonuclease 1
TRIB2 tribbles pseudokinase 2
TTC38 tetratricopeptide repeat domain 38
USP10 ubiquitin specific peptidase 10
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
ZNF286A zinc finger protein 286A
ZNF43 zinc finger protein 43
ZNF710 zinc finger protein 710
ZNHIT2 zinc finger, HIT-type containing 2

decreased expression

Symbol Name
AFAP1 actin filament associated protein 1
AKIP1 A kinase (PRKA) interacting protein 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ARSJ arylsulfatase family, member J
BBS7 Bardet-Biedl syndrome 7
BCAS3 breast carcinoma amplified sequence 3
BOLA1 bolA family member 1
C16ORF58 chromosome 16 open reading frame 58
C17ORF70 chromosome 17 open reading frame 70
C1R complement component 1, r subcomponent
CALCOCO1 calcium binding and coiled-coil domain 1
CCBL1 cysteine conjugate-beta lyase, cytoplasmic
CCDC85C coiled-coil domain containing 85C
CCP110 centriolar coiled coil protein 110kDa
CD3EAP CD3e molecule, epsilon associated protein
CEP97 centrosomal protein 97kDa
CFAP44 cilia and flagella associated protein 44
CHMP6 charged multivesicular body protein 6
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
CNPY3 canopy FGF signaling regulator 3
CUEDC1 CUE domain containing 1
CXORF56 chromosome X open reading frame 56
DEPDC1 DEP domain containing 1
DET1 de-etiolated homolog 1 (Arabidopsis)
DHRS9 dehydrogenase/reductase (SDR family) member 9
DUSP8 dual specificity phosphatase 8
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDN1 endothelin 1
EFNB1 ephrin-B1
EIF5A2 eukaryotic translation initiation factor 5A2
EN2 engrailed homeobox 2
FBXW12 F-box and WD repeat domain containing 12
FKBPL FK506 binding protein like
FUZ fuzzy planar cell polarity protein
GLDC glycine dehydrogenase (decarboxylating)
GPR1 G protein-coupled receptor 1
HIST1H2AG histone cluster 1, H2ag
HIST1H3B histone cluster 1, H3b
HLX H2.0-like homeobox
HOXB5 homeobox B5
HOXC4 homeobox C4
IFI6 interferon, alpha-inducible protein 6
IL17RA interleukin 17 receptor A
IL32 interleukin 32
IL4R interleukin 4 receptor
IMPACT impact RWD domain protein
ITGB2 integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
KDM7A lysine (K)-specific demethylase 7A
KLHL3 kelch-like family member 3
LIMS2 LIM and senescent cell antigen-like domains 2
LOC100127972 uncharacterized LOC100127972
LOC100272216 uncharacterized LOC100272216
LRRC37A2 leucine rich repeat containing 37, member A2
LSM6 LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MCMBP minichromosome maintenance complex binding protein
METTL2B methyltransferase like 2B
MGC12488
MMP13 matrix metallopeptidase 13
MNX1 motor neuron and pancreas homeobox 1
MRPL52 mitochondrial ribosomal protein L52
MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like
NUP62CL nucleoporin 62kDa C-terminal like
OGFRL1 opioid growth factor receptor-like 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
PCBP4 poly(rC) binding protein 4
PCSK7 proprotein convertase subtilisin/kexin type 7
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
PPCDC phosphopantothenoylcysteine decarboxylase
RBL1 retinoblastoma-like 1
RNF2 ring finger protein 2
RNF31 ring finger protein 31
RPGR retinitis pigmentosa GTPase regulator
SCAMP4 secretory carrier membrane protein 4
SFMBT1 Scm-like with four mbt domains 1
SIRT2 sirtuin 2
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNHG20 small nucleolar RNA host gene 20
SPATA2L spermatogenesis associated 2-like
STK16 serine/threonine kinase 16
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TAGLN3 transgelin 3
TBC1D12 TBC1 domain family, member 12
TMC7 transmembrane channel-like 7
TMEM184C transmembrane protein 184C
TMEM40 transmembrane protein 40
TMOD3 tropomodulin 3 (ubiquitous)
TNFRSF14 tumor necrosis factor receptor superfamily, member 14
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TOM1 target of myb1 (chicken)
TOR3A torsin family 3, member A
TRAPPC6A trafficking protein particle complex 6A
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSC22D4 TSC22 domain family, member 4
TSKU tsukushi, small leucine rich proteoglycan
ZNF350 zinc finger protein 350
ZNF444 zinc finger protein 444
ZNF767P zinc finger family member 767, pseudogene