| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the homatropine-5477 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM22 | ADAM metallopeptidase domain 22 |
| ADORA1 | adenosine A1 receptor |
| ALDH7A1 | aldehyde dehydrogenase 7 family, member A1 |
| ALDOB | aldolase B, fructose-bisphosphate |
| AP2A2 | adaptor-related protein complex 2, alpha 2 subunit |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ATP6V1D | ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D |
| B3GNTL1 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1 |
| B9D1 | B9 protein domain 1 |
| BAIAP2 | BAI1-associated protein 2 |
| BAIAP3 | BAI1-associated protein 3 |
| BMP15 | bone morphogenetic protein 15 |
| C21ORF2 | chromosome 21 open reading frame 2 |
| C5AR1 | complement component 5a receptor 1 |
| CACNA1I | calcium channel, voltage-dependent, T type, alpha 1I subunit |
| CCDC132 | coiled-coil domain containing 132 |
| CD47 | CD47 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) |
| CELA2A | chymotrypsin-like elastase family, member 2A |
| CFP | complement factor properdin |
| CHRNA3 | cholinergic receptor, nicotinic, alpha 3 (neuronal) |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CUL4B | cullin 4B |
| CYP4B1 | cytochrome P450, family 4, subfamily B, polypeptide 1 |
| CYTH1 | cytohesin 1 |
| DYNC1LI2 | dynein, cytoplasmic 1, light intermediate chain 2 |
| ELAVL2 | ELAV like neuron-specific RNA binding protein 2 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 |
| ETV5 | ets variant 5 |
| EVI5 | ecotropic viral integration site 5 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FLJ11292 | |
| FST | follistatin |
| GEMIN8 | gem (nuclear organelle) associated protein 8 |
| GGA2 | golgi-associated, gamma adaptin ear containing, ARF binding protein 2 |
| GGT1 | gamma-glutamyltransferase 1 |
| GLRX3 | glutaredoxin 3 |
| GLS | glutaminase |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide |
| GPR15 | G protein-coupled receptor 15 |
| HFE | hemochromatosis |
| HIPK3 | homeodomain interacting protein kinase 3 |
| HOXA9 | homeobox A9 |
| ITGB4 | integrin, beta 4 |
| KCNJ5 | potassium channel, inwardly rectifying subfamily J, member 5 |
| KRT2 | keratin 2, type II |
| LAPTM5 | lysosomal protein transmembrane 5 |
| LIG4 | ligase IV, DNA, ATP-dependent |
| MAGEA3 | melanoma antigen family A3 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MAPRE2 | microtubule-associated protein, RP/EB family, member 2 |
| MARS | methionyl-tRNA synthetase |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) |
| MMP3 | matrix metallopeptidase 3 |
| NOX1 | NADPH oxidase 1 |
| NPY | neuropeptide Y |
| PDZD2 | PDZ domain containing 2 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PLD2 | phospholipase D2 |
| PON3 | paraoxonase 3 |
| PQBP1 | polyglutamine binding protein 1 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha |
| PTGDR | prostaglandin D2 receptor (DP) |
| PYGB | phosphorylase, glycogen; brain |
| RAI2 | retinoic acid induced 2 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RHEB | Ras homolog enriched in brain |
| RNF6 | ring finger protein (C3H2C3 type) 6 |
| RPGR | retinitis pigmentosa GTPase regulator |
| RPL10L | ribosomal protein L10-like |
| SCN11A | sodium channel, voltage gated, type XI alpha subunit |
| SCRN3 | secernin 3 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SGK2 | serum/glucocorticoid regulated kinase 2 |
| SLC12A4 | solute carrier family 12 (potassium/chloride transporter), member 4 |
| SLC5A2 | solute carrier family 5 (sodium/glucose cotransporter), member 2 |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| SPAM1 | sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding) |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STAT5B | signal transducer and activator of transcription 5B |
| STON1 | stonin 1 |
| TMEM259 | transmembrane protein 259 |
| TMEM63A | transmembrane protein 63A |
| TMPRSS6 | transmembrane protease, serine 6 |
| TRIM23 | tripartite motif containing 23 |
| TRIM48 | tripartite motif containing 48 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UBA7 | ubiquitin-like modifier activating enzyme 7 |
| VHL | von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase |
| VPS41 | vacuolar protein sorting 41 homolog (S. cerevisiae) |
| WDR76 | WD repeat domain 76 |
| ZC3H13 | zinc finger CCCH-type containing 13 |
| ZMYND8 | zinc finger, MYND-type containing 8 |
| ZNF287 | zinc finger protein 287 |
| ZNRF4 | zinc and ring finger 4 |
| Symbol | Name |
|---|---|
| ALDOC | aldolase C, fructose-bisphosphate |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARMC7 | armadillo repeat containing 7 |
| ATAD3A | ATPase family, AAA domain containing 3A |
| ATG9A | autophagy related 9A |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase |
| C2ORF44 | chromosome 2 open reading frame 44 |
| C5 | complement component 5 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CCDC94 | coiled-coil domain containing 94 |
| CD302 | CD302 molecule |
| CHMP6 | charged multivesicular body protein 6 |
| CLDND1 | claudin domain containing 1 |
| CLSPN | claspin |
| CNNM4 | cyclin and CBS domain divalent metal cation transport mediator 4 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| CRLF1 | cytokine receptor-like factor 1 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| ERO1L | ERO1-like (S. cerevisiae) |
| EYA2 | EYA transcriptional coactivator and phosphatase 2 |
| F8 | coagulation factor VIII, procoagulant component |
| FAM86C1 | family with sequence similarity 86, member C1 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FBXO31 | F-box protein 31 |
| FCHO1 | FCH domain only 1 |
| FGGY | FGGY carbohydrate kinase domain containing |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GATA6 | GATA binding protein 6 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| HIST1H2BJ | histone cluster 1, H2bj |
| HMOX1 | heme oxygenase 1 |
| IL15RA | interleukin 15 receptor, alpha |
| INO80D | INO80 complex subunit D |
| INTS9 | integrator complex subunit 9 |
| IRF2BP1 | interferon regulatory factor 2 binding protein 1 |
| JMJD4 | jumonji domain containing 4 |
| KAT2A | K(lysine) acetyltransferase 2A |
| KLK5 | kallikrein-related peptidase 5 |
| LNPEP | leucyl/cystinyl aminopeptidase |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MITF | microphthalmia-associated transcription factor |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NIPAL2 | NIPA-like domain containing 2 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NPL | N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) |
| NPY5R | neuropeptide Y receptor Y5 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| PARPBP | PARP1 binding protein |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLA2G3 | phospholipase A2, group III |
| PLEKHO1 | pleckstrin homology domain containing, family O member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| POMZP3 | POM121 and ZP3 fusion |
| PRRG2 | proline rich Gla (G-carboxyglutamic acid) 2 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RNH1 | ribonuclease/angiogenin inhibitor 1 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| SARS2 | seryl-tRNA synthetase 2, mitochondrial |
| SETMAR | SET domain and mariner transposase fusion gene |
| SGPP1 | sphingosine-1-phosphate phosphatase 1 |
| SH2D4A | SH2 domain containing 4A |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SNIP1 | Smad nuclear interacting protein 1 |
| SPINK5 | serine peptidase inhibitor, Kazal type 5 |
| STBD1 | starch binding domain 1 |
| STX1A | syntaxin 1A (brain) |
| TBX19 | T-box 19 |
| TESC | tescalcin |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) |
| TMEM115 | transmembrane protein 115 |
| TMEM159 | transmembrane protein 159 |
| TMEM183A | transmembrane protein 183A |
| TMEM53 | transmembrane protein 53 |
| TRPV1 | transient receptor potential cation channel, subfamily V, member 1 |
| TTC23 | tetratricopeptide repeat domain 23 |
| TWF2 | twinfilin actin binding protein 2 |
| XKR8 | XK, Kell blood group complex subunit-related family, member 8 |
| ZNF34 | zinc finger protein 34 |
| ZNF442 | zinc finger protein 442 |
| ZNF639 | zinc finger protein 639 |
| ZNF696 | zinc finger protein 696 |
| ZNF747 | zinc finger protein 747 |
| ZSCAN26 | zinc finger and SCAN domain containing 26 |
