homologous chromosome segregation Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description The cell cycle process in which replicated homologous chromosomes are organized and then physically separated and apportioned to two sets during the first division of the meiotic cell cycle. Each replicated chromosome, composed of two sister chromatids, aligns at the cell equator, paired with its homologous partner; this pairing off, referred to as synapsis, permits genetic recombination. One homolog (both sister chromatids) of each morphologic type goes into each of the resulting chromosome sets. (Gene Ontology, GO_0045143)
External Link http://amigo.geneontology.org/amigo/term/GO:0045143
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Genes

22 genes participating in the homologous chromosome segregation biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ANKRD31 ankyrin repeat domain 31
C14ORF39 chromosome 14 open reading frame 39
FANCD2 Fanconi anemia, complementation group D2
FMN2 formin 2
IHO1 interactor of HORMAD1 1
KASH5 KASH domain containing 5
MAJIN membrane anchored junction protein
MEI4 meiosis-specific 4 homolog (S. cerevisiae)
MEIKIN meiotic kinetochore factor
MEIOB meiosis specific with OB domains
MND1 meiotic nuclear divisions 1 homolog (S. cerevisiae)
PRDM9 PR domain containing 9
PSMC3IP PSMC3 interacting protein
PTTG1 pituitary tumor-transforming 1
PTTG2 pituitary tumor-transforming 2
RNF212 ring finger protein 212
RNF212B ring finger protein 212B
SIRT7 sirtuin 7
SYCP1 synaptonemal complex protein 1
TERB1 telomere repeat binding bouquet formation protein 1
TERB2 telomere repeat binding bouquet formation protein 2
ZCWPW1 zinc finger, CW type with PWWP domain 1