homology Gene Set

Dataset GeneRIF Biological Term Annotations
Category structural or functional annotations
Type biological term
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Genes

400 genes co-occuring with the biological term homology in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symbol Name
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group)
ABCE1 ATP-binding cassette, sub-family E (OABP), member 1
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ACAP1 ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSL1 acyl-CoA synthetase long-chain family member 1
ACTN3 actinin, alpha 3 (gene/pseudogene)
ADAM33 ADAM metallopeptidase domain 33
ADAP1 ArfGAP with dual PH domains 1
ADORA2A adenosine A2a receptor
ADRB2 adrenoceptor beta 2, surface
ADRBK1 adrenergic, beta, receptor kinase 1
AFM afamin
AIFM3 apoptosis-inducing factor, mitochondrion-associated, 3
AIRE autoimmune regulator
AKAP13 A kinase (PRKA) anchor protein 13
AKR1C4 aldo-keto reductase family 1, member C4
AKR1D1 aldo-keto reductase family 1, member D1
AKT1 v-akt murine thymoma viral oncogene homolog 1
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALOX15B arachidonate 15-lipoxygenase, type B
APBB1IP amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
APOA1 apolipoprotein A-I
APOL1 apolipoprotein L, 1
APOL6 apolipoprotein L, 6
APP amyloid beta (A4) precursor protein
AQP2 aquaporin 2 (collecting duct)
ARF1 ADP-ribosylation factor 1
ARHGAP8 Rho GTPase activating protein 8
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARHGEF25 Rho guanine nucleotide exchange factor (GEF) 25
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL5B ADP-ribosylation factor-like 5B
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2
ATP7B ATPase, Cu++ transporting, beta polypeptide
AURKB aurora kinase B
AVPR2 arginine vasopressin receptor 2
AXL AXL receptor tyrosine kinase
BAALC brain and acute leukemia, cytoplasmic
BACE1 beta-site APP-cleaving enzyme 1
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BAIAP2 BAI1-associated protein 2
BAK1 BCL2-antagonist/killer 1
BANP BTG3 associated nuclear protein
BAX BCL2-associated X protein
BCL2 B-cell CLL/lymphoma 2
BCL2L10 BCL2-like 10 (apoptosis facilitator)
BCL2L13 BCL2-like 13 (apoptosis facilitator)
BCL3 B-cell CLL/lymphoma 3
BEST1 bestrophin 1
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit
CACNA1E calcium channel, voltage-dependent, R type, alpha 1E subunit
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAPN10 calpain 10
CCNB1 cyclin B1
CD19 CD19 molecule
CD28 CD28 molecule
CD300A CD300a molecule
CD4 CD4 molecule
CD84 CD84 molecule
CDC14A cell division cycle 14A
CDC14B cell division cycle 14B
CDC5L cell division cycle 5-like
CDCA3 cell division cycle associated 3
CDKL3 cyclin-dependent kinase-like 3
CERK ceramide kinase
CERKL ceramide kinase-like
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
CHN2 chimerin 2
CHPF2 chondroitin polymerizing factor 2
CHRNA7 cholinergic receptor, nicotinic, alpha 7 (neuronal)
CLCN1 chloride channel, voltage-sensitive 1
CLNS1A chloride channel, nucleotide-sensitive, 1A
CNN1 calponin 1, basic, smooth muscle
CNR1 cannabinoid receptor 1 (brain)
COL23A1 collagen, type XXIII, alpha 1
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRNN cornulin
CRYBB2 crystallin, beta B2
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
CTAG1B cancer/testis antigen 1B
CTAG2 cancer/testis antigen 2
CTNS cystinosin, lysosomal cystine transporter
CTTN cortactin
CXCL12 chemokine (C-X-C motif) ligand 12
CXCL14 chemokine (C-X-C motif) ligand 14
CXCR1 chemokine (C-X-C motif) receptor 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
CYP4A22 cytochrome P450, family 4, subfamily A, polypeptide 22
CYP7B1 cytochrome P450, family 7, subfamily B, polypeptide 1
DAAM1 dishevelled associated activator of morphogenesis 1
DCLRE1B DNA cross-link repair 1B
DDIT3 DNA-damage-inducible transcript 3
DDX41 DEAD (Asp-Glu-Ala-Asp) box polypeptide 41
DGKG diacylglycerol kinase, gamma 90kDa
DIAPH1 diaphanous-related formin 1
DLC1 DLC1 Rho GTPase activating protein
DNM1 dynamin 1
DNM2 dynamin 2
DNMT1 DNA (cytosine-5-)-methyltransferase 1
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK2 docking protein 2, 56kDa
DOK7 docking protein 7
E2F3 E2F transcription factor 3
EDA ectodysplasin A
EDC3 enhancer of mRNA decapping 3
EGFR epidermal growth factor receptor
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
EIF2B2 eukaryotic translation initiation factor 2B, subunit 2 beta, 39kDa
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa
EIF2B5 eukaryotic translation initiation factor 2B, subunit 5 epsilon, 82kDa
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
EPB41 erythrocyte membrane protein band 4.1
EPB42 erythrocyte membrane protein band 4.2
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2 erb-b2 receptor tyrosine kinase 2
ESR2 estrogen receptor 2 (ER beta)
EXPH5 exophilin 5
F10 coagulation factor X
F11R F11 receptor
F8 coagulation factor VIII, procoagulant component
FAM20A family with sequence similarity 20, member A
FASA fertility associated sperm antigen
FASLG Fas ligand (TNF superfamily, member 6)
FERMT3 fermitin family member 3
FES FES proto-oncogene, tyrosine kinase
FHOD1 formin homology 2 domain containing 1
FLNA filamin A, alpha
FLNB filamin B, beta
FMO3 flavin containing monooxygenase 3
FOXO3 forkhead box O3
FOXO3B forkhead box O3B pseudogene
FPR1 formyl peptide receptor 1
FPR2 formyl peptide receptor 2
FRK fyn-related Src family tyrosine kinase
FUBP1 far upstream element (FUSE) binding protein 1
GABRA1 gamma-aminobutyric acid (GABA) A receptor, alpha 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GGCX gamma-glutamyl carboxylase
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GKN2 gastrokine 2
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
GRB2 growth factor receptor-bound protein 2
GRIA1 glutamate receptor, ionotropic, AMPA 1
GRK5 G protein-coupled receptor kinase 5
GRK6 G protein-coupled receptor kinase 6
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa
HCK HCK proto-oncogene, Src family tyrosine kinase
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HEY2 hes-related family bHLH transcription factor with YRPW motif 2
HGF hepatocyte growth factor (hepapoietin A; scatter factor)
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HLA-G major histocompatibility complex, class I, G
HRH4 histamine receptor H4
HTR3A 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
IFT20 intraflagellar transport 20
IFT74 intraflagellar transport 74
IFT81 intraflagellar transport 81
IGF1 insulin-like growth factor 1 (somatomedin C)
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3
IGFBP3 insulin-like growth factor binding protein 3
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL23R interleukin 23 receptor
IL2RB interleukin 2 receptor, beta
IL36RN interleukin 36 receptor antagonist
ILK integrin-linked kinase
INF2 inverted formin, FH2 and WH2 domain containing
INPP5D inositol polyphosphate-5-phosphatase, 145kDa
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
IRS3P insulin receptor substrate 3, pseudogene
ISL1 ISL LIM homeobox 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITGB3 integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61)
ITSN1 intersectin 1 (SH3 domain protein)
JAG1 jagged 1
JAG2 jagged 2
JAK2 Janus kinase 2
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ1 potassium channel, voltage gated KQT-like subfamily Q, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA0907 KIAA0907
KIRREL2 kin of IRRE like 2 (Drosophila)
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLK3 kallikrein-related peptidase 3
KMT2E lysine (K)-specific methyltransferase 2E
L2HGDH L-2-hydroxyglutarate dehydrogenase
LAT linker for activation of T cells
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LDB1 LIM domain binding 1
LDLR low density lipoprotein receptor
LGI1 leucine-rich, glioma inactivated 1
LHX3 LIM homeobox 3
LIG1 ligase I, DNA, ATP-dependent
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MAP1S microtubule-associated protein 1S
MAP2K2 mitogen-activated protein kinase kinase 2
MAPK14 mitogen-activated protein kinase 14
MAPKAP1 mitogen-activated protein kinase associated protein 1
MCF2 MCF.2 cell line derived transforming sequence
MCF2L MCF.2 cell line derived transforming sequence-like
MCL1 myeloid cell leukemia 1
MCMBP minichromosome maintenance complex binding protein
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MED13L mediator complex subunit 13-like
MEIOB meiosis specific with OB domains
MEST mesoderm specific transcript
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1
MIR365A microRNA 365a
MIR98 microRNA 98
MIRLET7A1 microRNA let-7a-1
MLPH melanophilin
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC17 mucin 17, cell surface associated
MUSK muscle, skeletal, receptor tyrosine kinase
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYCN v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
MYO1G myosin IG
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
MYRIP myosin VIIA and Rab interacting protein
NCF1 neutrophil cytosolic factor 1
NCK2 NCK adaptor protein 2
NCR2 natural cytotoxicity triggering receptor 2
NEK8 NIMA-related kinase 8
NODAL nodal growth differentiation factor
NOTCH1 notch 1
NOX1 NADPH oxidase 1
NPHS1 nephrosis 1, congenital, Finnish type (nephrin)
NPR1 natriuretic peptide receptor 1
NPR2 natriuretic peptide receptor 2
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NRBP1 nuclear receptor binding protein 1
NUDCD2 NudC domain containing 2
OGT O-linked N-acetylglucosamine (GlcNAc) transferase
ORC6 origin recognition complex, subunit 6
P2RY2 purinergic receptor P2Y, G-protein coupled, 2
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCSK9 proprotein convertase subtilisin/kexin type 9
PDCD6IP programmed cell death 6 interacting protein
PDGFC platelet derived growth factor C
PDPK1 3-phosphoinositide dependent protein kinase 1
PER3 period circadian clock 3
PGM2L1 phosphoglucomutase 2-like 1
PHEX phosphate regulating endopeptidase homolog, X-linked
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PLCB2 phospholipase C, beta 2
PLCD1 phospholipase C, delta 1
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCH1 phospholipase C, eta 1
PLD1 phospholipase D1, phosphatidylcholine-specific
PLD2 phospholipase D2
PLEK pleckstrin
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
PLEKHB2 pleckstrin homology domain containing, family B (evectins) member 2
PLEKHG2 pleckstrin homology domain containing, family G (with RhoGef domain) member 2
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5
PLXNB2 plexin B2
PON1 paraoxonase 1
PPL periplakin
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PREP prolyl endopeptidase
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PROCR protein C receptor, endothelial
PRPF19 pre-mRNA processing factor 19
PTEN phosphatase and tensin homolog
PTK2 protein tyrosine kinase 2
PTK6 protein tyrosine kinase 6
PTP4A3 protein tyrosine phosphatase type IVA, member 3
PTPN2 protein tyrosine phosphatase, non-receptor type 2
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTPRS protein tyrosine phosphatase, receptor type, S
QTRT1 queuine tRNA-ribosyltransferase 1
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAD51 RAD51 recombinase
RAD52 RAD52 homolog (S. cerevisiae)
RAP1A RAP1A, member of RAS oncogene family
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2
RASGRF1 Ras protein-specific guanine nucleotide-releasing factor 1
RASGRF2 Ras protein-specific guanine nucleotide-releasing factor 2
RECQL4 RecQ protein-like 4
REL v-rel avian reticuloendotheliosis viral oncogene homolog
RET ret proto-oncogene
RHCE Rh blood group, CcEe antigens
RHEB Ras homolog enriched in brain
RHOA ras homolog family member A
RHOU ras homolog family member U
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SEC14L3 SEC14-like 3 (S. cerevisiae)
SGK3 serum/glucocorticoid regulated kinase family, member 3
SH2B3 SH2B adaptor protein 3
SH3PXD2A SH3 and PX domains 2A
SHARPIN SHANK-associated RH domain interactor
SIRPA signal-regulatory protein alpha
SKOR1 SKI family transcriptional corepressor 1
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SLC41A1 solute carrier family 41 (magnesium transporter), member 1
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group)
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SLC6A13 solute carrier family 6 (neurotransmitter transporter), member 13
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC6A4 solute carrier family 6 (neurotransmitter transporter), member 4
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1
SMN1 survival of motor neuron 1, telomeric
SNCAIP synuclein, alpha interacting protein
SNCB synuclein, beta
SNX10 sorting nexin 10
SNX11 sorting nexin 11
SNX2 sorting nexin 2
SOCS4 suppressor of cytokine signaling 4
SOS1 son of sevenless homolog 1 (Drosophila)
SP1 Sp1 transcription factor
SPRY4 sprouty homolog 4 (Drosophila)
SPTB spectrin, beta, erythrocytic
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SS18L1 synovial sarcoma translocation gene on chromosome 18-like 1
SSX1 synovial sarcoma, X breakpoint 1
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STX1A syntaxin 1A (brain)
STX2 syntaxin 2
SYT10 synaptotagmin X
SYTL1 synaptotagmin-like 1
SYTL2 synaptotagmin-like 2
SYTL3 synaptotagmin-like 3
SYTL4 synaptotagmin-like 4
SYTL5 synaptotagmin-like 5
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TDGF1 teratocarcinoma-derived growth factor 1
TG thyroglobulin
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
TJP1 tight junction protein 1
TLR4 toll-like receptor 4
TLR7 toll-like receptor 7
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TNFRSF12A tumor necrosis factor receptor superfamily, member 12A
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNIP1 TNFAIP3 interacting protein 1
TNIP2 TNFAIP3 interacting protein 2
TNIP3 TNFAIP3 interacting protein 3
TNK2 tyrosine kinase, non-receptor, 2
TNS1 tensin 1
TP53 tumor protein p53
TP63 tumor protein p63
TRABD2A TraB domain containing 2A
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TRIO trio Rho guanine nucleotide exchange factor
TSC2 tuberous sclerosis 2
TSC22D4 TSC22 domain family, member 4
TSPY1 testis specific protein, Y-linked 1
TTN titin
TYK2 tyrosine kinase 2
TYMS thymidylate synthetase
TYR tyrosinase
UTS2R urotensin 2 receptor
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
WASF1 WAS protein family, member 1
WDR35 WD repeat domain 35
WRN Werner syndrome, RecQ helicase-like
XPA xeroderma pigmentosum, complementation group A
XPO1 exportin 1
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZNF469 zinc finger protein 469