homosalate-3879 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the homosalate-3879 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
ADAM23 ADAM metallopeptidase domain 23
ALOX5 arachidonate 5-lipoxygenase
APC adenomatous polyposis coli
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARL3 ADP-ribosylation factor-like 3
ARSD arylsulfatase D
ART1 ADP-ribosyltransferase 1
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2
ATXN7L1 ataxin 7-like 1
BARX2 BARX homeobox 2
BAX BCL2-associated X protein
BDNF brain-derived neurotrophic factor
BHLHE41 basic helix-loop-helix family, member e41
C11ORF16 chromosome 11 open reading frame 16
C20ORF195 chromosome 20 open reading frame 195
CADM3 cell adhesion molecule 3
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD248 CD248 molecule, endosialin
CEND1 cell cycle exit and neuronal differentiation 1
CEP41 centrosomal protein 41kDa
CLIC2 chloride intracellular channel 2
COL4A6 collagen, type IV, alpha 6
CRTC1 CREB regulated transcription coactivator 1
DUSP4 dual specificity phosphatase 4
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
EGR1 early growth response 1
EMID1 EMI domain containing 1
EPX eosinophil peroxidase
ERO1LB ERO1-like beta (S. cerevisiae)
FAM13A family with sequence similarity 13, member A
FBXO4 F-box protein 4
GSK3A glycogen synthase kinase 3 alpha
GSTP1 glutathione S-transferase pi 1
GSTTP1 glutathione S-transferase theta pseudogene 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HMOX1 heme oxygenase 1
IGLJ3 immunoglobulin lambda joining 3
IRF8 interferon regulatory factor 8
ITIH5 inter-alpha-trypsin inhibitor heavy chain family, member 5
JUN jun proto-oncogene
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2
KIAA1456 KIAA1456
KLF13 Kruppel-like factor 13
KLHL29 kelch-like family member 29
KSR1 kinase suppressor of ras 1
L1CAM L1 cell adhesion molecule
LBP lipopolysaccharide binding protein
LCMT2 leucine carboxyl methyltransferase 2
LOXL3 lysyl oxidase-like 3
LPCAT4 lysophosphatidylcholine acyltransferase 4
MAPK8IP3 mitogen-activated protein kinase 8 interacting protein 3
MAX MYC associated factor X
ME3 malic enzyme 3, NADP(+)-dependent, mitochondrial
MED25 mediator complex subunit 25
MSX2 msh homeobox 2
NCF4 neutrophil cytosolic factor 4, 40kDa
NCOR2 nuclear receptor corepressor 2
NECAB2 N-terminal EF-hand calcium binding protein 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NUP188 nucleoporin 188kDa
OPRL1 opiate receptor-like 1
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PITX1 paired-like homeodomain 1
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRDM2 PR domain containing 2, with ZNF domain
PROSC proline synthetase co-transcribed homolog (bacterial)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RIOK3 RIO kinase 3
RPS28 ribosomal protein S28
SETD1B SET domain containing 1B
SKIL SKI-like proto-oncogene
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SPTBN5 spectrin, beta, non-erythrocytic 5
SSX3 synovial sarcoma, X breakpoint 3
SUGP1 SURP and G patch domain containing 1
SUN1 Sad1 and UNC84 domain containing 1
TBL1X transducin (beta)-like 1X-linked
TCP10L t-complex 10-like
TENM4 teneurin transmembrane protein 4
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TREM1 triggering receptor expressed on myeloid cells 1
TRIM10 tripartite motif containing 10
TRIO trio Rho guanine nucleotide exchange factor
TRPC1 transient receptor potential cation channel, subfamily C, member 1
TTC22 tetratricopeptide repeat domain 22
UBE2B ubiquitin-conjugating enzyme E2B
WFDC8 WAP four-disulfide core domain 8
ZBTB6 zinc finger and BTB domain containing 6
ZFP64 ZFP64 zinc finger protein
ZNF695 zinc finger protein 695

decreased expression

Symbol Name
ADTRP androgen-dependent TFPI-regulating protein
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
ALOX12 arachidonate 12-lipoxygenase
ALS2CL ALS2 C-terminal like
ANKRD40 ankyrin repeat domain 40
BFSP1 beaded filament structural protein 1, filensin
C22ORF46 chromosome 22 open reading frame 46
CA5BP1 carbonic anhydrase VB pseudogene 1
CAMK1 calcium/calmodulin-dependent protein kinase I
CCDC121 coiled-coil domain containing 121
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae)
CD3D CD3d molecule, delta (CD3-TCR complex)
CDK6 cyclin-dependent kinase 6
CDKL3 cyclin-dependent kinase-like 3
CHRM3 cholinergic receptor, muscarinic 3
CHRNA6 cholinergic receptor, nicotinic, alpha 6 (neuronal)
CHST10 carbohydrate sulfotransferase 10
CYP2B7P cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene
DAAM2 dishevelled associated activator of morphogenesis 2
DBF4B DBF4 zinc finger B
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNM1 dynamin 1
DSCAM Down syndrome cell adhesion molecule
DTX2 deltex 2, E3 ubiquitin ligase
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENO3 enolase 3 (beta, muscle)
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FCHO1 FCH domain only 1
GAMT guanidinoacetate N-methyltransferase
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
GPRC5D G protein-coupled receptor, class C, group 5, member D
GTPBP2 GTP binding protein 2
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H2AJ histone cluster 1, H2aj
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXC4 homeobox C4
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
HSF4 heat shock transcription factor 4
IL22 interleukin 22
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNK5 potassium channel, two pore domain subfamily K, member 5
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLK8 kallikrein-related peptidase 8
KRT15 keratin 15, type I
LHX6 LIM homeobox 6
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MALL mal, T-cell differentiation protein-like
MAOB monoamine oxidase B
MAPK10 mitogen-activated protein kinase 10
MEFV Mediterranean fever
MFGE8 milk fat globule-EGF factor 8 protein
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MMP2 matrix metallopeptidase 2
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL52 mitochondrial ribosomal protein L52
MUC3B mucin 3B, cell surface associated
MXD3 MAX dimerization protein 3
NCALD neurocalcin delta
NKX3-2 NK3 homeobox 2
NPIPB15 nuclear pore complex interacting protein family, member B15
NPR3 natriuretic peptide receptor 3
PADI1 peptidyl arginine deiminase, type I
PLCD1 phospholipase C, delta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHS1 pleckstrin homology domain containing, family S member 1
POM121 POM121 transmembrane nucleoporin
POPDC3 popeye domain containing 3
PPT2 palmitoyl-protein thioesterase 2
PRODH proline dehydrogenase (oxidase) 1
PRSS53 protease, serine, 53
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RGL1 ral guanine nucleotide dissociation stimulator-like 1
RNF19A ring finger protein 19A, RBR E3 ubiquitin protein ligase
RNF39 ring finger protein 39
RPL10L ribosomal protein L10-like
S100A2 S100 calcium binding protein A2
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SGCG sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
SLC12A8 solute carrier family 12, member 8
SLC2A11 solute carrier family 2 (facilitated glucose transporter), member 11
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SOAT2 sterol O-acyltransferase 2
STARD3 StAR-related lipid transfer (START) domain containing 3
STIM1 stromal interaction molecule 1
STX1A syntaxin 1A (brain)
TCP10 t-complex 10
TFF2 trefoil factor 2
TUBA3C tubulin, alpha 3c
UPK3B uroplakin 3B
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WNT16 wingless-type MMTV integration site family, member 16
YIF1B Yip1 interacting factor homolog B (S. cerevisiae)
ZNF41 zinc finger protein 41
ZNF551 zinc finger protein 551