| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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198 genes differentially expressed following the homosalate-3879 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| A2M | alpha-2-macroglobulin |
| ADAM23 | ADAM metallopeptidase domain 23 |
| ALOX5 | arachidonate 5-lipoxygenase |
| APC | adenomatous polyposis coli |
| APOBEC3C | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C |
| ARL3 | ADP-ribosylation factor-like 3 |
| ARSD | arylsulfatase D |
| ART1 | ADP-ribosyltransferase 1 |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| ATXN7L1 | ataxin 7-like 1 |
| BARX2 | BARX homeobox 2 |
| BAX | BCL2-associated X protein |
| BDNF | brain-derived neurotrophic factor |
| BHLHE41 | basic helix-loop-helix family, member e41 |
| C11ORF16 | chromosome 11 open reading frame 16 |
| C20ORF195 | chromosome 20 open reading frame 195 |
| CADM3 | cell adhesion molecule 3 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CD248 | CD248 molecule, endosialin |
| CEND1 | cell cycle exit and neuronal differentiation 1 |
| CEP41 | centrosomal protein 41kDa |
| CLIC2 | chloride intracellular channel 2 |
| COL4A6 | collagen, type IV, alpha 6 |
| CRTC1 | CREB regulated transcription coactivator 1 |
| DUSP4 | dual specificity phosphatase 4 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| EGR1 | early growth response 1 |
| EMID1 | EMI domain containing 1 |
| EPX | eosinophil peroxidase |
| ERO1LB | ERO1-like beta (S. cerevisiae) |
| FAM13A | family with sequence similarity 13, member A |
| FBXO4 | F-box protein 4 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GSTP1 | glutathione S-transferase pi 1 |
| GSTTP1 | glutathione S-transferase theta pseudogene 1 |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 |
| HMOX1 | heme oxygenase 1 |
| IGLJ3 | immunoglobulin lambda joining 3 |
| IRF8 | interferon regulatory factor 8 |
| ITIH5 | inter-alpha-trypsin inhibitor heavy chain family, member 5 |
| JUN | jun proto-oncogene |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 |
| KIAA1456 | KIAA1456 |
| KLF13 | Kruppel-like factor 13 |
| KLHL29 | kelch-like family member 29 |
| KSR1 | kinase suppressor of ras 1 |
| L1CAM | L1 cell adhesion molecule |
| LBP | lipopolysaccharide binding protein |
| LCMT2 | leucine carboxyl methyltransferase 2 |
| LOXL3 | lysyl oxidase-like 3 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MAX | MYC associated factor X |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MED25 | mediator complex subunit 25 |
| MSX2 | msh homeobox 2 |
| NCF4 | neutrophil cytosolic factor 4, 40kDa |
| NCOR2 | nuclear receptor corepressor 2 |
| NECAB2 | N-terminal EF-hand calcium binding protein 2 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NUP188 | nucleoporin 188kDa |
| OPRL1 | opiate receptor-like 1 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha |
| PITX1 | paired-like homeodomain 1 |
| PML | promyelocytic leukemia |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) |
| PPP2R5B | protein phosphatase 2, regulatory subunit B', beta |
| PRDM2 | PR domain containing 2, with ZNF domain |
| PROSC | proline synthetase co-transcribed homolog (bacterial) |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 |
| RIOK3 | RIO kinase 3 |
| RPS28 | ribosomal protein S28 |
| SETD1B | SET domain containing 1B |
| SKIL | SKI-like proto-oncogene |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SPTBN5 | spectrin, beta, non-erythrocytic 5 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| SUGP1 | SURP and G patch domain containing 1 |
| SUN1 | Sad1 and UNC84 domain containing 1 |
| TBL1X | transducin (beta)-like 1X-linked |
| TCP10L | t-complex 10-like |
| TENM4 | teneurin transmembrane protein 4 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TREM1 | triggering receptor expressed on myeloid cells 1 |
| TRIM10 | tripartite motif containing 10 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 |
| TTC22 | tetratricopeptide repeat domain 22 |
| UBE2B | ubiquitin-conjugating enzyme E2B |
| WFDC8 | WAP four-disulfide core domain 8 |
| ZBTB6 | zinc finger and BTB domain containing 6 |
| ZFP64 | ZFP64 zinc finger protein |
| ZNF695 | zinc finger protein 695 |
| Symbol | Name |
|---|---|
| ADTRP | androgen-dependent TFPI-regulating protein |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) |
| ALOX12 | arachidonate 12-lipoxygenase |
| ALS2CL | ALS2 C-terminal like |
| ANKRD40 | ankyrin repeat domain 40 |
| BFSP1 | beaded filament structural protein 1, filensin |
| C22ORF46 | chromosome 22 open reading frame 46 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CAMK1 | calcium/calmodulin-dependent protein kinase I |
| CCDC121 | coiled-coil domain containing 121 |
| CCRN4L | CCR4 carbon catabolite repression 4-like (S. cerevisiae) |
| CD3D | CD3d molecule, delta (CD3-TCR complex) |
| CDK6 | cyclin-dependent kinase 6 |
| CDKL3 | cyclin-dependent kinase-like 3 |
| CHRM3 | cholinergic receptor, muscarinic 3 |
| CHRNA6 | cholinergic receptor, nicotinic, alpha 6 (neuronal) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CYP2B7P | cytochrome P450, family 2, subfamily B, polypeptide 7, pseudogene |
| DAAM2 | dishevelled associated activator of morphogenesis 2 |
| DBF4B | DBF4 zinc finger B |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 |
| DNM1 | dynamin 1 |
| DSCAM | Down syndrome cell adhesion molecule |
| DTX2 | deltex 2, E3 ubiquitin ligase |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ENO3 | enolase 3 (beta, muscle) |
| FADS2 | fatty acid desaturase 2 |
| FAM120C | family with sequence similarity 120C |
| FCHO1 | FCH domain only 1 |
| GAMT | guanidinoacetate N-methyltransferase |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) |
| GPRC5D | G protein-coupled receptor, class C, group 5, member D |
| GTPBP2 | GTP binding protein 2 |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 |
| HIST1H2AJ | histone cluster 1, H2aj |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HOXC4 | homeobox C4 |
| HSD17B1 | hydroxysteroid (17-beta) dehydrogenase 1 |
| HSF4 | heat shock transcription factor 4 |
| IL22 | interleukin 22 |
| KCNK12 | potassium channel, two pore domain subfamily K, member 12 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 |
| KCNS1 | potassium voltage-gated channel, modifier subfamily S, member 1 |
| KLK8 | kallikrein-related peptidase 8 |
| KRT15 | keratin 15, type I |
| LHX6 | LIM homeobox 6 |
| LYL1 | lymphoblastic leukemia associated hematopoiesis regulator 1 |
| MALL | mal, T-cell differentiation protein-like |
| MAOB | monoamine oxidase B |
| MAPK10 | mitogen-activated protein kinase 10 |
| MEFV | Mediterranean fever |
| MFGE8 | milk fat globule-EGF factor 8 protein |
| MMP17 | matrix metallopeptidase 17 (membrane-inserted) |
| MMP2 | matrix metallopeptidase 2 |
| MRM1 | mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) |
| MRPL52 | mitochondrial ribosomal protein L52 |
| MUC3B | mucin 3B, cell surface associated |
| MXD3 | MAX dimerization protein 3 |
| NCALD | neurocalcin delta |
| NKX3-2 | NK3 homeobox 2 |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NPR3 | natriuretic peptide receptor 3 |
| PADI1 | peptidyl arginine deiminase, type I |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHS1 | pleckstrin homology domain containing, family S member 1 |
| POM121 | POM121 transmembrane nucleoporin |
| POPDC3 | popeye domain containing 3 |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRODH | proline dehydrogenase (oxidase) 1 |
| PRSS53 | protease, serine, 53 |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGL1 | ral guanine nucleotide dissociation stimulator-like 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RNF39 | ring finger protein 39 |
| RPL10L | ribosomal protein L10-like |
| S100A2 | S100 calcium binding protein A2 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SGCG | sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein) |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC2A11 | solute carrier family 2 (facilitated glucose transporter), member 11 |
| SLC7A9 | solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOAT2 | sterol O-acyltransferase 2 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| STIM1 | stromal interaction molecule 1 |
| STX1A | syntaxin 1A (brain) |
| TCP10 | t-complex 10 |
| TFF2 | trefoil factor 2 |
| TUBA3C | tubulin, alpha 3c |
| UPK3B | uroplakin 3B |
| USP20 | ubiquitin specific peptidase 20 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YIF1B | Yip1 interacting factor homolog B (S. cerevisiae) |
| ZNF41 | zinc finger protein 41 |
| ZNF551 | zinc finger protein 551 |