hormone activity Gene Set

Dataset GO Molecular Function Annotations 2025
Category structural or functional annotations
Type molecular function
Description The action characteristic of a hormone, any substance formed in very small amounts in one specialized organ or group of cells and carried (sometimes in the bloodstream) to another organ or group of cells in the same organism, upon which it has a specific regulatory action. The term was originally applied to agents with a stimulatory physiological action in vertebrate animals (as opposed to a chalone, which has a depressant action). Usage is now extended to regulatory compounds in lower animals and plants, and to synthetic substances having comparable effects; all bind receptors and trigger some biological process. (Gene Ontology, GO_0005179)
External Link http://amigo.geneontology.org/amigo/term/GO:0005179
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Genes

89 genes performing the hormone activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.

Symbol Name
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
ADIPOQ adiponectin, C1Q and collagen domain containing
ADM adrenomedullin
ADM2 adrenomedullin 2
AGRP agouti related neuropeptide
AGXT alanine-glyoxylate aminotransferase
AMH anti-Mullerian hormone
APELA apelin receptor early endogenous ligand
APLN apelin
BGLAP bone gamma-carboxyglutamate (gla) protein
BMP10 bone morphogenetic protein 10
C1QTNF12 C1q and TNF related 12
CALCA calcitonin-related polypeptide alpha
CALCB calcitonin-related polypeptide beta
CCL25 chemokine (C-C motif) ligand 25
CCN3 cellular communication network factor 3
CGB1 chorionic gonadotropin, beta polypeptide 1
CGB2 chorionic gonadotropin, beta polypeptide 2
CHGA chromogranin A
CHGB chromogranin B
CHLSN cholesin
CORT cortistatin
CPAMD8 C3 and PZP-like, alpha-2-macroglobulin domain containing 8
CRH corticotropin releasing hormone
CSH1 chorionic somatomammotropin hormone 1 (placental lactogen)
CSH2 chorionic somatomammotropin hormone 2
CSHL1 chorionic somatomammotropin hormone-like 1
ECRG4 ECRG4 augurin precursor
EDN1 endothelin 1
EDN2 endothelin 2
EDN3 endothelin 3
EPX eosinophil peroxidase
ERFE erythroferrone
FBN1 fibrillin 1
FBN2 fibrillin 2
FSHB follicle stimulating hormone, beta polypeptide
GALP galanin-like peptide
GAST gastrin
GCG glucagon
GDF15 growth differentiation factor 15
GH1 growth hormone 1
GH2 growth hormone 2
GHRH growth hormone releasing hormone
GHRL ghrelin/obestatin prepropeptide
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone)
GNRH2 gonadotropin-releasing hormone 2
GPNMB glycoprotein (transmembrane) nmb
GUCA2A guanylate cyclase activator 2A (guanylin)
HAMP hepcidin antimicrobial peptide
HCRT hypocretin (orexin) neuropeptide precursor
IAPP islet amyloid polypeptide
IGF1 insulin-like growth factor 1 (somatomedin C)
INHA inhibin, alpha
INHBA inhibin, beta A
INHBB inhibin, beta B
INS insulin
INSL6 insulin-like 6
KNG1 kininogen 1
LEP leptin
METRN meteorin, glial cell differentiation regulator
METRNL meteorin, glial cell differentiation regulator-like
NLRP3 NLR family, pyrin domain containing 3
NPFF neuropeptide FF-amide peptide precursor
NPPA natriuretic peptide A
NPPB natriuretic peptide B
NPPC natriuretic peptide C
NPY neuropeptide Y
OXT oxytocin/neurophysin I prepropeptide
PARD3 par-3 family cell polarity regulator
PENK proenkephalin
PNOC prepronociceptin
POMC proopiomelanocortin
PPY pancreatic polypeptide
PRL prolactin
PRLH prolactin releasing hormone
PTHLH parathyroid hormone-like hormone
PTRH2 peptidyl-tRNA hydrolase 2
PYY peptide YY
QRFP pyroglutamylated RFamide peptide
REG3A regenerating islet-derived 3 alpha
RIPK2 receptor-interacting serine-threonine kinase 2
SCT secretin
SPX spexin hormone
SST somatostatin
TOR2A torsin family 2, member A
TRH thyrotropin-releasing hormone
UCMA upper zone of growth plate and cartilage matrix associated
UCN urocortin
VGF VGF nerve growth factor inducible