hsa-let-7c Gene Set

Dataset TargetScan Predicted Nonconserved microRNA Targets
Category genomics
Type microRNA
Description microRNA let-7c|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 406885)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-let-7c
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Genes

129 target genes of the hsa-let-7c microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

Symbol Name Standardized Value
PRR23A proline rich 23A 1.99187
ZBP1 Z-DNA binding protein 1 1.99187
ESR2 estrogen receptor 2 (ER beta) 1.99187
ARG2 arginase 2 1.99187
ZCCHC9 zinc finger, CCHC domain containing 9 1.99187
KIAA1429 KIAA1429 1.99187
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 1.99187
SIGLEC14 sialic acid binding Ig-like lectin 14 1.99187
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 1.99187
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.7397
ABT1 activator of basal transcription 1 1.7397
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B 1.7397
ATG10 autophagy related 10 1.7397
FMO4 flavin containing monooxygenase 4 1.7397
POLQ polymerase (DNA directed), theta 1.55165
ZNF343 zinc finger protein 343 1.55165
ZNF215 zinc finger protein 215 1.55165
IL22RA1 interleukin 22 receptor, alpha 1 1.55165
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 1.55165
C18ORF21 chromosome 18 open reading frame 21 1.55165
ZNF10 zinc finger protein 10 1.55165
ZNF792 zinc finger protein 792 1.40969
ZNF763 zinc finger protein 763 1.40969
POM121L12 POM121 transmembrane nucleoporin-like 12 1.40969
FAM20A family with sequence similarity 20, member A 1.40969
RPL36A ribosomal protein L36a 1.40969
SIGLEC5 sialic acid binding Ig-like lectin 5 1.40969
DDTL D-dopachrome tautomerase-like 1.40969
RBM19 RNA binding motif protein 19 1.40969
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.2992
CTPS2 CTP synthase 2 1.2992
STAG3 stromal antigen 3 1.2992
LHCGR luteinizing hormone/choriogonadotropin receptor 1.2992
TMEM144 transmembrane protein 144 1.2992
ST7L suppression of tumorigenicity 7 like 1.2992
PLA2G2F phospholipase A2, group IIF 1.2992
BTN2A1 butyrophilin, subfamily 2, member A1 1.2992
RMI2 RecQ mediated genome instability 2 1.2992
DOK3 docking protein 3 1.2992
CRTAM cytotoxic and regulatory T cell molecule 1.2992
SSX4 synovial sarcoma, X breakpoint 4 1.20993
SSX5 synovial sarcoma, X breakpoint 5 1.20993
AMACR alpha-methylacyl-CoA racemase 1.20993
SSX4B synovial sarcoma, X breakpoint 4B 1.20993
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 1.20993
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 1.20993
STARD4 StAR-related lipid transfer (START) domain containing 4 1.20993
IFT80 intraflagellar transport 80 1.20993
MUC4 mucin 4, cell surface associated 1.20993
RFT1 RFT1 homolog (S. cerevisiae) 1.13535
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 1.13535
SSX7 synovial sarcoma, X breakpoint 7 1.13535
SLC25A40 solute carrier family 25, member 40 1.13535
RGPD6 RANBP2-like and GRIP domain containing 6 1.13535
AGXT2 alanine--glyoxylate aminotransferase 2 1.13535
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 1.13535
PARP16 poly (ADP-ribose) polymerase family, member 16 1.13535
RGPD8 RANBP2-like and GRIP domain containing 8 1.13535
RGPD5 RANBP2-like and GRIP domain containing 5 1.13535
CD80 CD80 molecule 1.13535
SPRYD7 SPRY domain containing 7 1.13535
FNDC9 fibronectin type III domain containing 9 1.13535
ZNF587 zinc finger protein 587 1.07142
MMS22L MMS22-like, DNA repair protein 1.07142
HIST2H2BF histone cluster 2, H2bf 1.07142
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 1.07142
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 1.07142
RPL34 ribosomal protein L34 1.07142
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 1.07142
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 1.07142
KIF27 kinesin family member 27 1.0155
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 1.0155
ENTHD2 ENTH domain containing 2 1.0155
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 1.0155
ZNF268 zinc finger protein 268 1.0155
FBXW4 F-box and WD repeat domain containing 4 1.0155
XG Xg blood group 1.0155
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 1.0155
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.965816
C3ORF38 chromosome 3 open reading frame 38 0.965816
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.965816
ZNF417 zinc finger protein 417 0.965816
KRT5 keratin 5, type II 0.965816
FAM122C family with sequence similarity 122C 0.965816
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.965816
ODF2L outer dense fiber of sperm tails 2-like 0.965816
C17ORF102 chromosome 17 open reading frame 102 0.965816
AGBL1 ATP/GTP binding protein-like 1 0.965816
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 0.965816
STARD9 StAR-related lipid transfer (START) domain containing 9 0.965816
NUGGC nuclear GTPase, germinal center associated 0.965816
USB1 U6 snRNA biogenesis 1 0.921135
NOTCH2NL notch 2 N-terminal like 0.921135
MAN2A2 mannosidase, alpha, class 2A, member 2 0.921135
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.921135
NAT14 N-acetyltransferase 14 (GCN5-related, putative) 0.921135
DAPK2 death-associated protein kinase 2 0.921135
SGK494 uncharacterized serine/threonine-protein kinase SgK494 0.921135
SUOX sulfite oxidase 0.921135
CASZ1 castor zinc finger 1 0.880544
C19ORF54 chromosome 19 open reading frame 54 0.880544
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 0.880544
ZNF577 zinc finger protein 577 0.880544
CCL16 chemokine (C-C motif) ligand 16 0.880544
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.880544
ABHD14B abhydrolase domain containing 14B 0.880544
WDR73 WD repeat domain 73 0.880544
TEKT4P2 tektin 4 pseudogene 2 0.880544
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.880544
C15ORF41 chromosome 15 open reading frame 41 0.880544
FMO2 flavin containing monooxygenase 2 (non-functional) 0.843347
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.843347
TMEM167A transmembrane protein 167A 0.843347
DCN decorin 0.843347
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.843347
DTX3L deltex 3 like, E3 ubiquitin ligase 0.843347
RFWD3 ring finger and WD repeat domain 3 0.843347
TFEC transcription factor EC 0.843347
ANAPC13 anaphase promoting complex subunit 13 0.843347
RBM12B RNA binding motif protein 12B 0.843347
PDLIM7 PDZ and LIM domain 7 (enigma) 0.843347
PLGLB1 plasminogen-like B1 0.809003
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.809003
AURKA aurora kinase A 0.809003
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.809003
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.809003
PLGLB2 plasminogen-like B2 0.809003
GOLGA6L9 golgin A6 family-like 9 0.809003
EMB embigin 0.809003