hsa-let-7d Gene Set

Dataset TargetScan Predicted Nonconserved microRNA Targets
Category genomics
Type microRNA
Description microRNA let-7d|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 406886)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-let-7d
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Genes

130 target genes of the hsa-let-7d microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

Symbol Name Standardized Value
ZCCHC9 zinc finger, CCHC domain containing 9 1.99187
ZBP1 Z-DNA binding protein 1 1.99187
KIAA1429 KIAA1429 1.99187
ARG2 arginase 2 1.99187
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative) 1.99187
ESR2 estrogen receptor 2 (ER beta) 1.99187
PRR23A proline rich 23A 1.99187
SIGLEC14 sialic acid binding Ig-like lectin 14 1.99187
CYP4F2 cytochrome P450, family 4, subfamily F, polypeptide 2 1.99187
ABT1 activator of basal transcription 1 1.7397
ZNF792 zinc finger protein 792 1.7397
PPAPDC1B phosphatidic acid phosphatase type 2 domain containing 1B 1.7397
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.7397
C18ORF21 chromosome 18 open reading frame 21 1.55165
ZNF215 zinc finger protein 215 1.55165
TSEN34 TSEN34 tRNA splicing endonuclease subunit 1.55165
ZNF10 zinc finger protein 10 1.55165
IL22RA1 interleukin 22 receptor, alpha 1 1.55165
SIGLEC5 sialic acid binding Ig-like lectin 5 1.55165
ATG10 autophagy related 10 1.55165
ZNF343 zinc finger protein 343 1.55165
FMO4 flavin containing monooxygenase 4 1.55165
RBM19 RNA binding motif protein 19 1.40969
DOK3 docking protein 3 1.40969
LHCGR luteinizing hormone/choriogonadotropin receptor 1.40969
TMEM144 transmembrane protein 144 1.40969
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like 1.40969
ZNF763 zinc finger protein 763 1.40969
POM121L12 POM121 transmembrane nucleoporin-like 12 1.40969
DDTL D-dopachrome tautomerase-like 1.40969
RPL36A ribosomal protein L36a 1.2992
POLQ polymerase (DNA directed), theta 1.2992
SSX4 synovial sarcoma, X breakpoint 4 1.2992
STAG3 stromal antigen 3 1.2992
SSX5 synovial sarcoma, X breakpoint 5 1.2992
SSX4B synovial sarcoma, X breakpoint 4B 1.2992
PLA2G2F phospholipase A2, group IIF 1.2992
RMI2 RecQ mediated genome instability 2 1.2992
CRTAM cytotoxic and regulatory T cell molecule 1.2992
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae) 1.2992
SDR42E1 short chain dehydrogenase/reductase family 42E, member 1 1.2992
BTN2A1 butyrophilin, subfamily 2, member A1 1.2992
ST7L suppression of tumorigenicity 7 like 1.2992
MUC4 mucin 4, cell surface associated 1.20993
ZNF587 zinc finger protein 587 1.20993
RPL34 ribosomal protein L34 1.20993
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae) 1.20993
STARD4 StAR-related lipid transfer (START) domain containing 4 1.20993
SSX7 synovial sarcoma, X breakpoint 7 1.20993
IFT80 intraflagellar transport 80 1.20993
FAM20A family with sequence similarity 20, member A 1.20993
CTPS2 CTP synthase 2 1.20993
FNDC9 fibronectin type III domain containing 9 1.20993
RGPD8 RANBP2-like and GRIP domain containing 8 1.13535
PARP16 poly (ADP-ribose) polymerase family, member 16 1.13535
RGPD6 RANBP2-like and GRIP domain containing 6 1.13535
AMACR alpha-methylacyl-CoA racemase 1.13535
SPRYD7 SPRY domain containing 7 1.13535
RGPD5 RANBP2-like and GRIP domain containing 5 1.13535
SLC25A40 solute carrier family 25, member 40 1.13535
C17ORF102 chromosome 17 open reading frame 102 1.13535
CD80 CD80 molecule 1.13535
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila) 1.13535
CASZ1 castor zinc finger 1 1.07142
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila) 1.07142
AGXT2 alanine--glyoxylate aminotransferase 2 1.07142
RFT1 RFT1 homolog (S. cerevisiae) 1.0155
PKD1L2 polycystic kidney disease 1-like 2 (gene/pseudogene) 1.0155
GPIHBP1 glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 1.0155
XG Xg blood group 1.0155
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) 1.0155
HIST2H2BF histone cluster 2, H2bf 1.0155
ZNF268 zinc finger protein 268 0.965816
KIF27 kinesin family member 27 0.965816
AGBL1 ATP/GTP binding protein-like 1 0.965816
USB1 U6 snRNA biogenesis 1 0.965816
FAM122C family with sequence similarity 122C 0.965816
PRIM2 primase, DNA, polypeptide 2 (58kDa) 0.965816
MMS22L MMS22-like, DNA repair protein 0.965816
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.965816
FBXW4 F-box and WD repeat domain containing 4 0.965816
DAPK2 death-associated protein kinase 2 0.965816
STARD9 StAR-related lipid transfer (START) domain containing 9 0.921135
UGT3A1 UDP glycosyltransferase 3 family, polypeptide A1 0.921135
KRT5 keratin 5, type II 0.921135
ODF2L outer dense fiber of sperm tails 2-like 0.921135
MAN2A2 mannosidase, alpha, class 2A, member 2 0.921135
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.921135
ZC3HAV1 zinc finger CCCH-type, antiviral 1 0.921135
DARS2 aspartyl-tRNA synthetase 2, mitochondrial 0.921135
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2 0.921135
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1 0.921135
ZNF417 zinc finger protein 417 0.921135
NUDT15 nudix (nucleoside diphosphate linked moiety X)-type motif 15 0.921135
DTX3L deltex 3 like, E3 ubiquitin ligase 0.921135
C3ORF38 chromosome 3 open reading frame 38 0.921135
ENTHD2 ENTH domain containing 2 0.921135
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1 0.880544
TMEM167A transmembrane protein 167A 0.880544
EMB embigin 0.880544
ZNF577 zinc finger protein 577 0.880544
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9 0.880544
ABHD14B abhydrolase domain containing 14B 0.880544
PDLIM7 PDZ and LIM domain 7 (enigma) 0.880544
TEKT4P2 tektin 4 pseudogene 2 0.880544
NOTCH2NL notch 2 N-terminal like 0.880544
SUOX sulfite oxidase 0.880544
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase) 0.880544
NAT14 N-acetyltransferase 14 (GCN5-related, putative) 0.880544
SMARCAD1 SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 0.880544
C19ORF54 chromosome 19 open reading frame 54 0.880544
DCN decorin 0.843347
LOC100507462 uncharacterized LOC100507462 0.843347
PLGLB1 plasminogen-like B1 0.843347
NUGGC nuclear GTPase, germinal center associated 0.843347
PLCB2 phospholipase C, beta 2 0.843347
WDR73 WD repeat domain 73 0.843347
PLGLB2 plasminogen-like B2 0.843347
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.843347
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.809003
FAM120C family with sequence similarity 120C 0.809003
GAB3 GRB2-associated binding protein 3 0.809003
FMO2 flavin containing monooxygenase 2 (non-functional) 0.809003
C15ORF41 chromosome 15 open reading frame 41 0.809003
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1 0.809003
RBM12B RNA binding motif protein 12B 0.809003
GOLGA6L9 golgin A6 family-like 9 0.809003
TFEC transcription factor EC 0.809003
CCL16 chemokine (C-C motif) ligand 16 0.809003
RFWD3 ring finger and WD repeat domain 3 0.809003