hsa-miR-345 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 345|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 442910)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-345
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Genes

171 target genes of the hsa-miR-345 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
SMAD1 SMAD family member 1 1.45615
CTTNBP2NL CTTNBP2 N-terminal like 1.45615
C8ORF86 chromosome 8 open reading frame 86 1.45615
LAT2 linker for activation of T cells family, member 2 1.45615
RFC1 replication factor C (activator 1) 1, 145kDa 1.26663
HSPA12A heat shock 70kDa protein 12A 1.26663
ZNF598 zinc finger protein 598 1.26663
GPR3 G protein-coupled receptor 3 1.26663
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha 1.26663
OLFM3 olfactomedin 3 1.26663
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5 1.11641
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila) 1.11641
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 1.11641
HABP4 hyaluronan binding protein 4 1.11641
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4 1.11641
ZNF689 zinc finger protein 689 1.11641
EPN3 epsin 3 1.11641
DHCR24 24-dehydrocholesterol reductase 0.997906
CRTAM cytotoxic and regulatory T cell molecule 0.997906
PAX8 paired box 8 0.997906
CNBP CCHC-type zinc finger, nucleic acid binding protein 0.997906
IL1F10 interleukin 1 family, member 10 (theta) 0.997906
SZRD1 SUZ RNA binding domain containing 1 0.997906
GMEB2 glucocorticoid modulatory element binding protein 2 0.90397
C8ORF44 chromosome 8 open reading frame 44 0.90397
RUNX3 runt-related transcription factor 3 0.90397
PDE4DIP phosphodiesterase 4D interacting protein 0.90397
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 0.90397
RPA1 replication protein A1, 70kDa 0.90397
IP6K2 inositol hexakisphosphate kinase 2 0.90397
C12ORF4 chromosome 12 open reading frame 4 0.90397
BSN bassoon presynaptic cytomatrix protein 0.90397
TFE3 transcription factor binding to IGHM enhancer 3 0.828473
USP46 ubiquitin specific peptidase 46 0.828473
NEK7 NIMA-related kinase 7 0.828473
SORBS1 sorbin and SH3 domain containing 1 0.766596
FLJ45513 uncharacterized LOC729220 0.766596
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 0.714812
PALD1 phosphatase domain containing, paladin 1 0.714812
TOB1 transducer of ERBB2, 1 0.714812
LPAR2 lysophosphatidic acid receptor 2 0.714812
USP15 ubiquitin specific peptidase 15 0.714812
RBM41 RNA binding motif protein 41 0.714812
AIDA axin interactor, dorsalization associated 0.670641
LFNG LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase 0.670641
KMT2C lysine (K)-specific methyltransferase 2C 0.632343
EPS8 epidermal growth factor receptor pathway substrate 8 0.632343
RAB3B RAB3B, member RAS oncogene family 0.632343
MTDH metadherin 0.598666
CAPN6 calpain 6 0.598666
TUB tubby bipartite transcription factor 0.568687
GALNTL6 polypeptide N-acetylgalactosaminyltransferase-like 6 0.568687
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit 0.541706
ELAVL1 ELAV like RNA binding protein 1 0.541706
USP54 ubiquitin specific peptidase 54 0.517189
CD5 CD5 molecule 0.517189
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.517189
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha 0.49473
UHMK1 U2AF homology motif (UHM) kinase 1 0.49473
USP50 ubiquitin specific peptidase 50 0.49473
KLHDC10 kelch domain containing 10 0.49473
MED8 mediator complex subunit 8 0.49473
BUB3 BUB3 mitotic checkpoint protein 0.474009
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase 0.474009
SSBP2 single-stranded DNA binding protein 2 0.454769
JADE1 jade family PHD finger 1 0.454769
RAB3D RAB3D, member RAS oncogene family 0.436802
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 0.436802
IRF1 interferon regulatory factor 1 0.436802
RAB39B RAB39B, member RAS oncogene family 0.419947
PEX19 peroxisomal biogenesis factor 19 0.419947
TMEM106B transmembrane protein 106B 0.419947
RC3H1 ring finger and CCCH-type domains 1 0.419947
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma 0.404082
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.389112
PCP4L1 Purkinje cell protein 4 like 1 0.389112
MON2 MON2 homolog (S. cerevisiae) 0.361556
MUS81 MUS81 structure-specific endonuclease subunit 0.361556
GRAPL GRB2-related adaptor protein-like 0.32519
ADIG adipogenin 0.31417
SLC7A14 solute carrier family 7, member 14 0.31417
ADCY6 adenylate cyclase 6 0.31417
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 0.293524
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) 0.293524
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.274552
HOXA3 homeobox A3 0.274552
RASL10B RAS-like, family 10, member B 0.274552
EDEM3 ER degradation enhancer, mannosidase alpha-like 3 0.241055
INHBB inhibin, beta B 0.23348
FZD5 frizzled class receptor 5 0.219115
BAZ2A bromodomain adjacent to zinc finger domain, 2A 0.219115
TMEM110 transmembrane protein 110 0.212286
ZNF135 zinc finger protein 135 0.199275
ZNF236 zinc finger protein 236 0.199275
KITLG KIT ligand 0.193083
BEND4 BEN domain containing 4 0.187098
FRMD6 FERM domain containing 6 0.181316
PGAP1 post-GPI attachment to proteins 1 0.181316
STX11 syntaxin 11 0.181316
CPD carboxypeptidase D 0.175726
AK2 adenylate kinase 2 0.159923
MAN2A2 mannosidase, alpha, class 2A, member 2 0.154935
TBC1D30 TBC1 domain family, member 30 0.154935
RORA RAR-related orphan receptor A 0.154935
KRI1 KRI1 homolog (S. cerevisiae) 0.15008
DBNL drebrin-like 0.15008
TMPRSS4 transmembrane protease, serine 4 0.145356
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.145356
MAGIX MAGI family member, X-linked 0.140752
C7ORF60 chromosome 7 open reading frame 60 0.140752
LIPH lipase, member H 0.136254
LIMD2 LIM domain containing 2 0.136254
JPH4 junctophilin 4 0.131849
ST6GAL2 ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 0.131849
GID4 GID complex subunit 4 0.131849
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 0.127531
RBSN rabenosyn, RAB effector 0.127531
LZTS2 leucine zipper, putative tumor suppressor 2 0.123298
PHIP pleckstrin homology domain interacting protein 0.123298
CYB561D1 cytochrome b561 family, member D1 0.119151
ITPRIPL2 inositol 1,4,5-trisphosphate receptor interacting protein-like 2 0.115091
ARSB arylsulfatase B 0.115091
FAM214B family with sequence similarity 214, member B 0.115091
RNF222 ring finger protein 222 0.115091
WAC WW domain containing adaptor with coiled-coil 0.115091
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.107229
CBLL1 Cbl proto-oncogene-like 1, E3 ubiquitin protein ligase 0.103424
KMT2D lysine (K)-specific methyltransferase 2D 0.103424
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 0.099701
LSM8 LSM8 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.092495
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.085563
BBC3 BCL2 binding component 3 0.082179
STEAP3 STEAP family member 3, metalloreductase 0.078844
TRPS1 trichorhinophalangeal syndrome I 0.078844
FAM126B family with sequence similarity 126, member B 0.078844
CLOCK clock circadian regulator 0.075559
IPCEF1 interaction protein for cytohesin exchange factors 1 0.069137
BCL9L B-cell CLL/lymphoma 9-like 0.069137
CYB5RL cytochrome b5 reductase-like 0.065994
FAM178A family with sequence similarity 178, member A 0.062888
SORT1 sortilin 1 0.059817
H1F0 H1 histone family, member 0 0.056784
CELF3 CUGBP, Elav-like family member 3 0.056784
TRERF1 transcriptional regulating factor 1 0.053794
ALX4 ALX homeobox 4 0.050854
GABBR2 gamma-aminobutyric acid (GABA) B receptor, 2 0.050854
MMP16 matrix metallopeptidase 16 (membrane-inserted) 0.047969
SETBP1 SET binding protein 1 0.042355
RAPGEF3 Rap guanine nucleotide exchange factor (GEF) 3 0.042355
EIF5 eukaryotic translation initiation factor 5 0.039622
TRIM25 tripartite motif containing 25 0.039622
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 0.03694
SRL sarcalumenin 0.034317
SPRY3 sprouty homolog 3 (Drosophila) 0.031759
FBXW11 F-box and WD repeat domain containing 11 0.031759
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.029271
MINOS1-NBL1 MINOS1-NBL1 readthrough 0.029271
FBXL20 F-box and leucine-rich repeat protein 20 0.026857
QKI QKI, KH domain containing, RNA binding 0.026857
FOXP2 forkhead box P2 0.02452
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.02452
MTMR3 myotubularin related protein 3 0.02452
ILDR2 immunoglobulin-like domain containing receptor 2 0.02226
MCTP2 multiple C2 domains, transmembrane 2 0.020071
SEPT11 septin 11 0.017945
SH3TC2 SH3 domain and tetratricopeptide repeats 2 0.013856
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.009975
UBIAD1 UbiA prenyltransferase domain containing 1 0.009975
IDS iduronate 2-sulfatase 0.006367
APLN apelin 0.003282
TLN2 talin 2 0.002088