hsa-miR-375 Gene Set

Dataset MiRTarBase microRNA Targets
Category physical interactions
Type microRNA
Description microRNA 375|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 494324)
External Link http://mirtarbase.mbc.nctu.edu.tw/php/detail.php?mirtid=MIRT000053
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Genes

420 target genes of the hsa-miR-375 microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

Symbol Name
ABHD4 abhydrolase domain containing 4
ABI2 abl-interactor 2
ACSL3 acyl-CoA synthetase long-chain family member 3
ACSL4 acyl-CoA synthetase long-chain family member 4
ADIPOR2 adiponectin receptor 2
AEBP2 AE binding protein 2
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AGTPBP1 ATP/GTP binding protein 1
AHCYL1 adenosylhomocysteinase-like 1
AKAP7 A kinase (PRKA) anchor protein 7
ALMS1 Alstrom syndrome protein 1
AMMECR1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ANKRD46 ankyrin repeat domain 46
APH1B APH1B gamma secretase subunit
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
AQP11 aquaporin 11
ARHGAP11A Rho GTPase activating protein 11A
ARL2BP ADP-ribosylation factor-like 2 binding protein
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASAP2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
ATG7 autophagy related 7
AXL AXL receptor tyrosine kinase
AZI2 5-azacytidine induced 2
B3GALNT1 beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
BAK1 BCL2-antagonist/killer 1
BATF2 basic leucine zipper transcription factor, ATF-like 2
BAZ1A bromodomain adjacent to zinc finger domain, 1A
BCL10 B-cell CLL/lymphoma 10
BCL2 B-cell CLL/lymphoma 2
BCL2L11 BCL2-like 11 (apoptosis facilitator)
BDH2 3-hydroxybutyrate dehydrogenase, type 2
BIRC3 baculoviral IAP repeat containing 3
BOD1L1 biorientation of chromosomes in cell division 1-like 1
BSN bassoon presynaptic cytomatrix protein
C11ORF54 chromosome 11 open reading frame 54
C12ORF29 chromosome 12 open reading frame 29
C14ORF159 chromosome 14 open reading frame 159
C15ORF41 chromosome 15 open reading frame 41
C15ORF57 chromosome 15 open reading frame 57
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
C1QBP complement component 1, q subcomponent binding protein
CAB39 calcium binding protein 39
CALU calumenin
CARD8 caspase recruitment domain family, member 8
CASP3 caspase 3, apoptosis-related cysteine peptidase
CBWD2 COBW domain containing 2
CBWD3 COBW domain containing 3
CCDC59 coiled-coil domain containing 59
CCDC88A coiled-coil domain containing 88A
CCDC88B coiled-coil domain containing 88B
CDC42 cell division cycle 42
CDCA7L cell division cycle associated 7-like
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
CDR2 cerebellar degeneration-related protein 2, 62kDa
CELF2 CUGBP, Elav-like family member 2
CENPF centromere protein F, 350/400kDa
CEP128 centrosomal protein 128kDa
CEP19 centrosomal protein 19kDa
CEP44 centrosomal protein 44kDa
CEP57L1 centrosomal protein 57kDa-like 1
CEP70 centrosomal protein 70kDa
CFL2 cofilin 2 (muscle)
CHGB chromogranin B
CHPF chondroitin polymerizing factor
CHPT1 choline phosphotransferase 1
CHSY1 chondroitin sulfate synthase 1
CKAP2 cytoskeleton associated protein 2
CLDN1 claudin 1
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CMTM4 CKLF-like MARVEL transmembrane domain containing 4
CNN3 calponin 3, acidic
COG2 component of oligomeric golgi complex 2
COL12A1 collagen, type XII, alpha 1
CORO1C coronin, actin binding protein, 1C
COX20 COX20 cytochrome c oxidase assembly factor
CPOX coproporphyrinogen oxidase
CRABP2 cellular retinoic acid binding protein 2
CREB3 cAMP responsive element binding protein 3
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like)
CRLF1 cytokine receptor-like factor 1
CRLF3 cytokine receptor-like factor 3
CSTF2 cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
CTDSP2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
CTGF connective tissue growth factor
CTSC cathepsin C
CUL5 cullin 5
CXADR coxsackie virus and adenovirus receptor
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAZAP2 DAZ associated protein 2
DCTN5 dynactin 5 (p25)
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4
DESI1 desumoylating isopeptidase 1
DGKD diacylglycerol kinase, delta 130kDa
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila)
DISP2 dispatched homolog 2 (Drosophila)
DLG4 discs, large homolog 4 (Drosophila)
DNAH11 dynein, axonemal, heavy chain 11
DNAJC2 DnaJ (Hsp40) homolog, subfamily C, member 2
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta
DOK7 docking protein 7
DPY19L1 dpy-19-like 1 (C. elegans)
DPYSL3 dihydropyrimidinase-like 3
DR1 down-regulator of transcription 1, TBP-binding (negative cofactor 2)
DUSP6 dual specificity phosphatase 6
DUT deoxyuridine triphosphatase
EBAG9 estrogen receptor binding site associated, antigen, 9
EBPL emopamil binding protein-like
EEA1 early endosome antigen 1
EFNB2 ephrin-B2
EFTUD2 elongation factor Tu GTP binding domain containing 2
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
ELAVL4 ELAV like neuron-specific RNA binding protein 4
ELL2 elongation factor, RNA polymerase II, 2
EMC3 ER membrane protein complex subunit 3
EMP1 epithelial membrane protein 1
ENAH enabled homolog (Drosophila)
ENOPH1 enolase-phosphatase 1
ERP44 endoplasmic reticulum protein 44
ESPNL espin-like
EXO1 exonuclease 1
EXOC6 exocyst complex component 6
EXT1 exostosin glycosyltransferase 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAH fumarylacetoacetate hydrolase (fumarylacetoacetase)
FAM126B family with sequence similarity 126, member B
FAM3C family with sequence similarity 3, member C
FAM63B family with sequence similarity 63, member B
FAM89A family with sequence similarity 89, member A
FAM96A family with sequence similarity 96, member A
FBXO8 F-box protein 8
FKBP1A FK506 binding protein 1A, 12kDa
FKBP1B FK506 binding protein 1B, 12.6 kDa
FOLR1 folate receptor 1 (adult)
FSTL3 follistatin-like 3 (secreted glycoprotein)
FYTTD1 forty-two-three domain containing 1
FZD4 frizzled class receptor 4
FZD8 frizzled class receptor 8
GALM galactose mutarotase (aldose 1-epimerase)
GAS8 growth arrest-specific 8
GATA6 GATA binding protein 6
GATAD1 GATA zinc finger domain containing 1
GDAP1 ganglioside induced differentiation associated protein 1
GFM2 G elongation factor, mitochondrial 2
GKAP1 G kinase anchoring protein 1
GOLGA4 golgin A4
GPR157 G protein-coupled receptor 157
GRPEL2 GrpE-like 2, mitochondrial (E. coli)
GSC goosecoid homeobox
GTPBP4 GTP binding protein 4
HDHD1 haloacid dehalogenase-like hydrolase domain containing 1
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HEY1 hes-related family bHLH transcription factor with YRPW motif 1
HK2 hexokinase 2
HN1 hematological and neurological expressed 1
HOMER2 homer scaffolding protein 2
HOXB13 homeobox B13
HRSP12 heat-responsive protein 12
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
IDNK idnK, gluconokinase homolog (E. coli)
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT46 intraflagellar transport 46
IFT80 intraflagellar transport 80
IGFBP3 insulin-like growth factor binding protein 3
IL17RA interleukin 17 receptor A
IL1RAP interleukin 1 receptor accessory protein
INSIG2 insulin induced gene 2
IQCE IQ motif containing E
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
JAG1 jagged 1
JAK2 Janus kinase 2
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KCTD10 potassium channel tetramerization domain containing 10
KDSR 3-ketodihydrosphingosine reductase
KHK ketohexokinase (fructokinase)
KIAA0232 KIAA0232
KIAA0513 KIAA0513
KIAA1191 KIAA1191
KIAA1524 KIAA1524
KLHDC8B kelch domain containing 8B
KLHL7 kelch-like family member 7
KLK10 kallikrein-related peptidase 10
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRT8 keratin 8, type II
LDHB lactate dehydrogenase B
LEPROTL1 leptin receptor overlapping transcript-like 1
LHFPL2 lipoma HMGIC fusion partner-like 2
LIMD2 LIM domain containing 2
LITAF lipopolysaccharide-induced TNF factor
LMAN2 lectin, mannose-binding 2
LPCAT1 lysophosphatidylcholine acyltransferase 1
LSM12 LSM12 homolog (S. cerevisiae)
LYPD5 LY6/PLAUR domain containing 5
MAP2K4 mitogen-activated protein kinase kinase 4
MAP3K8 mitogen-activated protein kinase kinase kinase 8
MAPKAP1 mitogen-activated protein kinase associated protein 1
MAT2B methionine adenosyltransferase II, beta
MBD2 methyl-CpG binding domain protein 2
MED8 mediator complex subunit 8
METTL2A methyltransferase like 2A
METTL2B methyltransferase like 2B
MIR17HG miR-17-92 cluster host gene
MKRN1 makorin ring finger protein 1
MLEC malectin
MNS1 meiosis-specific nuclear structural 1
MOSPD3 motile sperm domain containing 3
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MR1 major histocompatibility complex, class I-related
MRE11A MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
MREG melanoregulin
MTDH metadherin
MTPN myotrophin
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NAT10 N-acetyltransferase 10 (GCN5-related)
NCAM1 neural cell adhesion molecule 1
NCOA7 nuclear receptor coactivator 7
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NELFCD negative elongation factor complex member C/D
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2
NIN ninein (GSK3B interacting protein)
NLE1 notchless homolog 1 (Drosophila)
NOLC1 nucleolar and coiled-body phosphoprotein 1
NPPB natriuretic peptide B
NRBP1 nuclear receptor binding protein 1
NSFL1C NSFL1 (p97) cofactor (p47)
NT5C2 5'-nucleotidase, cytosolic II
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21
NUMB numb homolog (Drosophila)
NUPL1 nucleoporin like 1
NUS1 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae)
NXT2 nuclear transport factor 2-like export factor 2
ODF2 outer dense fiber of sperm tails 2
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1
OPA1 optic atrophy 1 (autosomal dominant)
OSBPL8 oxysterol binding protein-like 8
OTX1 orthodenticle homeobox 1
OXNAD1 oxidoreductase NAD-binding domain containing 1
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PAPD4 PAP associated domain containing 4
PAQR8 progestin and adipoQ receptor family member VIII
PARP1 poly (ADP-ribose) polymerase 1
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PCGF5 polycomb group ring finger 5
PDGFC platelet derived growth factor C
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PEBP1 phosphatidylethanolamine binding protein 1
PEX11B peroxisomal biogenesis factor 11 beta
PGM2 phosphoglucomutase 2
PHF20L1 PHD finger protein 20-like 1
PHF3 PHD finger protein 3
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHTF2 putative homeodomain transcription factor 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIK3IP1 phosphoinositide-3-kinase interacting protein 1
PLAG1 pleiomorphic adenoma gene 1
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3
POC1B POC1 centriolar protein B
PPCS phosphopantothenoylcysteine synthetase
PPP1R2 protein phosphatase 1, regulatory (inhibitor) subunit 2
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRDX1 peroxiredoxin 1
PRDX3 peroxiredoxin 3
PRKCA protein kinase C, alpha
PRKX protein kinase, X-linked
PROCR protein C receptor, endothelial
PRRT3 proline-rich transmembrane protein 3
PSIP1 PC4 and SFRS1 interacting protein 1
PSME4 proteasome (prosome, macropain) activator subunit 4
PTP4A2 protein tyrosine phosphatase type IVA, member 2
PTPMT1 protein tyrosine phosphatase, mitochondrial 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
RAB10 RAB10, member RAS oncogene family
RAB28 RAB28, member RAS oncogene family
RAB3B RAB3B, member RAS oncogene family
RAB3D RAB3D, member RAS oncogene family
RAB6A RAB6A, member RAS oncogene family
RAP2C RAP2C, member of RAS oncogene family
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RASD1 RAS, dexamethasone-induced 1
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RB1CC1 RB1-inducible coiled-coil 1
RBBP8 retinoblastoma binding protein 8
RBPJ recombination signal binding protein for immunoglobulin kappa J region
RCN2 reticulocalbin 2, EF-hand calcium binding domain
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
REEP3 receptor accessory protein 3
RHOA ras homolog family member A
RHOQ ras homolog family member Q
RIMS3 regulating synaptic membrane exocytosis 3
RLF rearranged L-myc fusion
RMDN3 regulator of microtubule dynamics 3
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1L RPGRIP1-like
RPN1 ribophorin I
RPN2 ribophorin II
RPUSD4 RNA pseudouridylate synthase domain containing 4
RRAGB Ras-related GTP binding B
RRAGC Ras-related GTP binding C
RTN2 reticulon 2
SAMD11 sterile alpha motif domain containing 11
SAMD4A sterile alpha motif domain containing 4A
SCLY selenocysteine lyase
SDC1 syndecan 1
SEC23A Sec23 homolog A (S. cerevisiae)
SEC24C SEC24 family member C
SEMA3C sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
SENP1 SUMO1/sentrin specific peptidase 1
SERP1 stress-associated endoplasmic reticulum protein 1
SERTAD2 SERTA domain containing 2
SESN1 sestrin 1
SET SET nuclear proto-oncogene
SETD7 SET domain containing (lysine methyltransferase) 7
SETD8 SET domain containing (lysine methyltransferase) 8
SFT2D2 SFT2 domain containing 2
SGMS2 sphingomyelin synthase 2
SGOL2 shugoshin-like 2 (S. pombe)
SH3BP4 SH3-domain binding protein 4
SH3D19 SH3 domain containing 19
SIPA1L3 signal-induced proliferation-associated 1 like 3
SKA2 spindle and kinetochore associated complex subunit 2
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
SLC25A42 solute carrier family 25, member 42
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4
SLC39A11 solute carrier family 39, member 11
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6
SNAPC1 small nuclear RNA activating complex, polypeptide 1, 43kDa
SNPH syntaphilin
SNRPA1 small nuclear ribonucleoprotein polypeptide A'
SNX25 sorting nexin 25
SP110 SP110 nuclear body protein
SPAG9 sperm associated antigen 9
SPRED1 sprouty-related, EVH1 domain containing 1
STAP2 signal transducing adaptor family member 2
STK38L serine/threonine kinase 38 like
STPG1 sperm-tail PG-rich repeat containing 1
STRBP spermatid perinuclear RNA binding protein
STX3 syntaxin 3
STX6 syntaxin 6
SUB1 SUB1 homolog (S. cerevisiae)
SUZ12 SUZ12 polycomb repressive complex 2 subunit
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein
SYT15 synaptotagmin XV
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa
TBC1D5 TBC1 domain family, member 5
TBX19 T-box 19
TCF12 transcription factor 12
TGFB2 transforming growth factor, beta 2
TGM2 transglutaminase 2
THRA thyroid hormone receptor, alpha
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMED5 transmembrane emp24 protein transport domain containing 5
TMED8 transmembrane emp24 protein transport domain containing 8
TMEM106B transmembrane protein 106B
TMEM145 transmembrane protein 145
TMEM170A transmembrane protein 170A
TMEM25 transmembrane protein 25
TMEM55A transmembrane protein 55A
TMEM74B transmembrane protein 74B
TMTC4 transmembrane and tetratricopeptide repeat containing 4
TMX3 thioredoxin-related transmembrane protein 3
TNFSF13 tumor necrosis factor (ligand) superfamily, member 13
TNNI3 troponin I type 3 (cardiac)
TNPO3 transportin 3
TNS3 tensin 3
TOR1AIP2 torsin A interacting protein 2
TPR translocated promoter region, nuclear basket protein
TPRG1L tumor protein p63 regulated 1-like
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae)
TSC22D2 TSC22 domain family, member 2
TTC7B tetratricopeptide repeat domain 7B
UBE3A ubiquitin protein ligase E3A
UBLCP1 ubiquitin-like domain containing CTD phosphatase 1
UCHL3 ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
UGCG UDP-glucose ceramide glucosyltransferase
UNC13B unc-13 homolog B (C. elegans)
USP1 ubiquitin specific peptidase 1
USP10 ubiquitin specific peptidase 10
USP31 ubiquitin specific peptidase 31
USP46 ubiquitin specific peptidase 46
UXS1 UDP-glucuronate decarboxylase 1
VASN vasorin
VEZT vezatin, adherens junctions transmembrane protein
VGLL4 vestigial-like family member 4
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae)
WDR1 WD repeat domain 1
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WTAP Wilms tumor 1 associated protein
WWC1 WW and C2 domain containing 1
WWC2 WW and C2 domain containing 2
XPR1 xenotropic and polytropic retrovirus receptor 1
YAP1 Yes-associated protein 1
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
YY1AP1 YY1 associated protein 1
ZBED1 zinc finger, BED-type containing 1
ZBTB8A zinc finger and BTB domain containing 8A
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZDHHC11 zinc finger, DHHC-type containing 11
ZFHX2 zinc finger homeobox 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZFP91 ZFP91 zinc finger protein
ZNF404 zinc finger protein 404
ZNF540 zinc finger protein 540
ZNF571 zinc finger protein 571
ZNF614 zinc finger protein 614
ZNF785 zinc finger protein 785