hsa-miR-375 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 375|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 494324)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-375
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Genes

226 target genes of the hsa-miR-375 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
RASD1 RAS, dexamethasone-induced 1 1.45615
ELAVL4 ELAV like neuron-specific RNA binding protein 4 1.45615
LRFN1 leucine rich repeat and fibronectin type III domain containing 1 1.45615
SHOX2 short stature homeobox 2 1.45615
HNF1B HNF1 homeobox B 1.45615
ISL2 ISL LIM homeobox 2 1.45615
PTPN4 protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) 1.45615
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 1.45615
BAHCC1 BAH domain and coiled-coil containing 1 1.26663
ARL4C ADP-ribosylation factor-like 4C 1.26663
SLC31A1 solute carrier family 31 (copper transporter), member 1 1.11641
ING5 inhibitor of growth family, member 5 1.11641
FOXF1 forkhead box F1 1.11641
CLCN2 chloride channel, voltage-sensitive 2 1.11641
ATXN1 ataxin 1 1.11641
LDHB lactate dehydrogenase B 0.997906
LRP5 low density lipoprotein receptor-related protein 5 0.997906
TRIM66 tripartite motif containing 66 0.90397
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 0.90397
PIPOX pipecolic acid oxidase 0.90397
IFT20 intraflagellar transport 20 0.828473
RBM47 RNA binding motif protein 47 0.828473
CEPT1 choline/ethanolamine phosphotransferase 1 0.828473
NME5 NME/NM23 family member 5 0.828473
PLXNA4 plexin A4 0.828473
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16 0.828473
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.766596
INSIG2 insulin induced gene 2 0.766596
ARRB1 arrestin, beta 1 0.766596
TSC1 tuberous sclerosis 1 0.714812
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2 0.714812
MAL2 mal, T-cell differentiation protein 2 (gene/pseudogene) 0.714812
PIAS1 protein inhibitor of activated STAT, 1 0.670641
UBE3A ubiquitin protein ligase E3A 0.632343
NXPH4 neurexophilin 4 0.632343
RBM24 RNA binding motif protein 24 0.632343
PDE5A phosphodiesterase 5A, cGMP-specific 0.568687
SOX21 SRY (sex determining region Y)-box 21 0.568687
SPAG9 sperm associated antigen 9 0.568687
CBX3 chromobox homolog 3 0.568687
GRIK5 glutamate receptor, ionotropic, kainate 5 0.541706
DIP2C DIP2 disco-interacting protein 2 homolog C (Drosophila) 0.541706
IKZF4 IKAROS family zinc finger 4 (Eos) 0.541706
TNPO3 transportin 3 0.541706
LUZP6 leucine zipper protein 6 0.541706
ANKHD1 ankyrin repeat and KH domain containing 1 0.541706
MTPN myotrophin 0.541706
MED13 mediator complex subunit 13 0.541706
STRADA STE20-related kinase adaptor alpha 0.541706
CEMIP cell migration inducing protein, hyaluronan binding 0.517189
UNC13A unc-13 homolog A (C. elegans) 0.517189
C11ORF54 chromosome 11 open reading frame 54 0.517189
SSTR1 somatostatin receptor 1 0.517189
G2E3 G2/M-phase specific E3 ubiquitin protein ligase 0.517189
KLF12 Kruppel-like factor 12 0.517189
C7ORF60 chromosome 7 open reading frame 60 0.517189
ATG2B autophagy related 2B 0.49473
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.474009
UST uronyl-2-sulfotransferase 0.474009
PAX6 paired box 6 0.474009
USPL1 ubiquitin specific peptidase like 1 0.474009
BMPR1B bone morphogenetic protein receptor, type IB 0.474009
OTP orthopedia homeobox 0.474009
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.454769
KIAA1804 mixed lineage kinase 4 0.454769
CCDC117 coiled-coil domain containing 117 0.454769
CHSY1 chondroitin sulfate synthase 1 0.454769
ATXN7 ataxin 7 0.436802
CADM1 cell adhesion molecule 1 0.436802
HOXA3 homeobox A3 0.419947
GRIK2 glutamate receptor, ionotropic, kainate 2 0.404082
SYP synaptophysin 0.37496
ADAT2 adenosine deaminase, tRNA-specific 2 0.37496
CAST calpastatin 0.37496
NOTCH2 notch 2 0.37496
ASCL1 achaete-scute family bHLH transcription factor 1 0.37496
LSM12 LSM12 homolog (S. cerevisiae) 0.37496
SLC11A2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 0.37496
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide 0.37496
NBEA neurobeachin 0.361556
MATR3 matrin 3 0.361556
TMEM65 transmembrane protein 65 0.361556
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 0.348832
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.348832
FZD4 frizzled class receptor 4 0.348832
SYNJ2BP synaptojanin 2 binding protein 0.348832
EIF1 eukaryotic translation initiation factor 1 0.336728
SHANK3 SH3 and multiple ankyrin repeat domains 3 0.336728
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 0.32519
ADGRL1 adhesion G protein-coupled receptor L1 0.31417
KLF4 Kruppel-like factor 4 (gut) 0.31417
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.31417
XKR6 XK, Kell blood group complex subunit-related family, member 6 0.31417
PDPK1 3-phosphoinositide dependent protein kinase 1 0.303626
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1 0.303626
DERL1 derlin 1 0.303626
SVIL supervillin 0.303626
RMDN3 regulator of microtubule dynamics 3 0.293524
ITGB1BP2 integrin beta 1 binding protein (melusin) 2 0.283838
ABI2 abl-interactor 2 0.283838
DESI1 desumoylating isopeptidase 1 0.283838
PROSER1 proline and serine rich 1 0.283838
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1) 0.283838
BCORL1 BCL6 corepressor-like 1 0.283838
EHMT1 euchromatic histone-lysine N-methyltransferase 1 0.283838
PRKAG2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit 0.283838
PRKD1 protein kinase D1 0.274552
PDE4D phosphodiesterase 4D, cAMP-specific 0.274552
ZFYVE26 zinc finger, FYVE domain containing 26 0.257113
ACSL3 acyl-CoA synthetase long-chain family member 3 0.257113
KLF5 Kruppel-like factor 5 (intestinal) 0.248923
PITPNA phosphatidylinositol transfer protein, alpha 0.248923
RIBC1 RIB43A domain with coiled-coils 1 0.241055
RS1 retinoschisin 1 0.23348
GRM5 glutamate receptor, metabotropic 5 0.23348
TSC22D2 TSC22 domain family, member 2 0.23348
FLG2 filaggrin family member 2 0.23348
C8ORF86 chromosome 8 open reading frame 86 0.226173
FRAS1 Fraser extracellular matrix complex subunit 1 0.212286
CPNE8 copine VIII 0.212286
TBR1 T-box, brain, 1 0.212286
C15ORF41 chromosome 15 open reading frame 41 0.212286
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 0.212286
ARHGAP35 Rho GTPase activating protein 35 0.205675
PHF21B PHD finger protein 21B 0.205675
GREB1 growth regulation by estrogen in breast cancer 1 0.199275
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.199275
ACSL5 acyl-CoA synthetase long-chain family member 5 0.199275
CCDC176 coiled-coil domain containing 176 0.193083
SERBP1 SERPINE1 mRNA binding protein 1 0.193083
CORO2A coronin, actin binding protein, 2A 0.193083
ENAH enabled homolog (Drosophila) 0.187098
IPO9 importin 9 0.187098
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 0.187098
MEIS1 Meis homeobox 1 0.187098
GATA6 GATA binding protein 6 0.187098
CSRNP2 cysteine-serine-rich nuclear protein 2 0.181316
NLK nemo-like kinase 0.181316
VAT1L vesicle amine transport 1-like 0.181316
ATF7 activating transcription factor 7 0.181316
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A 0.175726
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.17031
GREM2 gremlin 2, DAN family BMP antagonist 0.159923
KANK4 KN motif and ankyrin repeat domains 4 0.159923
TMEM26 transmembrane protein 26 0.154935
JAK2 Janus kinase 2 0.154935
ZRANB1 zinc finger, RAN-binding domain containing 1 0.154935
DLG3 discs, large homolog 3 (Drosophila) 0.154935
HABP2 hyaluronan binding protein 2 0.154935
PDGFA platelet-derived growth factor alpha polypeptide 0.15008
TCF12 transcription factor 12 0.145356
ELAVL2 ELAV like neuron-specific RNA binding protein 2 0.145356
WIBG within bgcn homolog (Drosophila) 0.145356
C7 complement component 7 0.145356
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.136254
C15ORF54 chromosome 15 open reading frame 54 0.131849
JUND jun D proto-oncogene 0.131849
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.131849
ANKMY2 ankyrin repeat and MYND domain containing 2 0.131849
BMPR2 bone morphogenetic protein receptor, type II (serine/threonine kinase) 0.131849
AGPS alkylglycerone phosphate synthase 0.127531
AEBP2 AE binding protein 2 0.127531
WDR92 WD repeat domain 92 0.123298
RTKN2 rhotekin 2 0.119151
QKI QKI, KH domain containing, RNA binding 0.111118
SCN2B sodium channel, voltage gated, type II beta subunit 0.111118
VTI1A vesicle transport through interaction with t-SNAREs 1A 0.107229
SKI SKI proto-oncogene 0.103424
KLLN killin, p53-regulated DNA replication inhibitor 0.103424
HDDC3 HD domain containing 3 0.103424
AHR aryl hydrocarbon receptor 0.099701
CASZ1 castor zinc finger 1 0.099701
HOXB3 homeobox B3 0.09606
RGS16 regulator of G-protein signaling 16 0.09606
ZFHX4 zinc finger homeobox 4 0.09606
SHB Src homology 2 domain containing adaptor protein B 0.092495
CTBP2 C-terminal binding protein 2 0.092495
PRDM16 PR domain containing 16 0.088999
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 0.088999
SRRM3 serine/arginine repetitive matrix 3 0.085563
EBF3 early B-cell factor 3 0.082179
TMEM135 transmembrane protein 135 0.078844
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.072324
SPRY3 sprouty homolog 3 (Drosophila) 0.069137
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 0.069137
GATAD2A GATA zinc finger domain containing 2A 0.065994
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.065994
ELAVL3 ELAV like neuron-specific RNA binding protein 3 0.059817
MBNL3 muscleblind-like splicing regulator 3 0.059817
VAX1 ventral anterior homeobox 1 0.059817
ITPKB inositol-trisphosphate 3-kinase B 0.056784
TNRC6B trinucleotide repeat containing 6B 0.056784
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.056784
CUX1 cut-like homeobox 1 0.053794
MBNL1 muscleblind-like splicing regulator 1 0.053794
ADCY6 adenylate cyclase 6 0.050854
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.050854
CREBZF CREB/ATF bZIP transcription factor 0.050854
PTPN3 protein tyrosine phosphatase, non-receptor type 3 0.047969
RBM27 RNA binding motif protein 27 0.042355
NR5A2 nuclear receptor subfamily 5, group A, member 2 0.042355
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.042355
PRPF4B pre-mRNA processing factor 4B 0.03694
WBP1L WW domain binding protein 1-like 0.034317
YAP1 Yes-associated protein 1 0.034317
WWC2 WW and C2 domain containing 2 0.031759
RTF1 Rtf1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae) 0.031759
TRPS1 trichorhinophalangeal syndrome I 0.029271
FBXO45 F-box protein 45 0.02452
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.02452
BNC2 basonuclin 2 0.02226
NCOA7 nuclear receptor coactivator 7 0.02226
SP1 Sp1 transcription factor 0.020071
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.020071
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.017945
PHF14 PHD finger protein 14 0.017945
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.015875
SOCS4 suppressor of cytokine signaling 4 0.013856
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.011888
CDKN2B cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) 0.011888
PURB purine-rich element binding protein B 0.006367
KIAA1549L KIAA1549-like 0.006367
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor) 0.006367
BVES blood vessel epicardial substance 0.004732
IGF1R insulin-like growth factor 1 receptor 0.004732
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35) 0.003282