hsa-miR-421 Gene Set

Dataset MiRTarBase microRNA Targets
Category physical interactions
Type microRNA
Description microRNA 421|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 693122)
External Link http://mirtarbase.mbc.nctu.edu.tw/php/detail.php?mirtid=MIRT001103
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Genes

143 target genes of the hsa-miR-421 microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

Symbol Name
ACOT9 acyl-CoA thioesterase 9
AFF4 AF4/FMR2 family, member 4
AGO1 argonaute RISC catalytic component 1
AHNAK AHNAK nucleoprotein
AMZ2 archaelysin family metallopeptidase 2
AP3B1 adaptor-related protein complex 3, beta 1 subunit
ATG2B autophagy related 2B
ATM ATM serine/threonine kinase
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATXN2L ataxin 2-like
CAP1 CAP, adenylate cyclase-associated protein 1 (yeast)
CASP2 caspase 2, apoptosis-related cysteine peptidase
CBX7 chromobox homolog 7
CD276 CD276 molecule
CD46 CD46 molecule, complement regulatory protein
CDC37 cell division cycle 37
CDC42SE2 CDC42 small effector 2
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEP57 centrosomal protein 57kDa
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
CNOT1 CCR4-NOT transcription complex, subunit 1
COPA coatomer protein complex, subunit alpha
COPRS coordinator of PRMT5, differentiation stimulator
CREBRF CREB3 regulatory factor
CREBZF CREB/ATF bZIP transcription factor
CTC1 CTS telomere maintenance complex component 1
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27
DOK4 docking protein 4
DUS3L dihydrouridine synthase 3-like (S. cerevisiae)
DUSP3 dual specificity phosphatase 3
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EIF3K eukaryotic translation initiation factor 3, subunit K
EIF4A1 eukaryotic translation initiation factor 4A1
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2
FAM122A family with sequence similarity 122A
FAM160B1 family with sequence similarity 160, member B1
FAM168B family with sequence similarity 168, member B
FAM172A family with sequence similarity 172, member A
FAM32A family with sequence similarity 32, member A
FAT2 FAT atypical cadherin 2
FBXO11 F-box protein 11
FKBP8 FK506 binding protein 8, 38kDa
GAREML GRB2 associated, regulator of MAPK1-like
GCSH glycine cleavage system protein H (aminomethyl carrier)
GFOD2 glucose-fructose oxidoreductase domain containing 2
GID4 GID complex subunit 4
GID8 GID complex subunit 8
GRK6 G protein-coupled receptor kinase 6
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HIST2H4B histone cluster 2, H4b
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HTT huntingtin
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ISY1 ISY1 splicing factor homolog (S. cerevisiae)
ITPK1 inositol-tetrakisphosphate 1-kinase
KIAA0100 KIAA0100
LARS2 leucyl-tRNA synthetase 2, mitochondrial
LBR lamin B receptor
LIMS1 LIM and senescent cell antigen-like domains 1
LIN7C lin-7 homolog C (C. elegans)
LMCD1 LIM and cysteine-rich domains 1
MAPK8 mitogen-activated protein kinase 8
MCFD2 multiple coagulation factor deficiency 2
MIS18BP1 MIS18 binding protein 1
MLXIP MLX interacting protein
MRPL38 mitochondrial ribosomal protein L38
MSL3 male-specific lethal 3 homolog (Drosophila)
MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
NCAPG non-SMC condensin I complex, subunit G
NCDN neurochondrin
NDC1 NDC1 transmembrane nucleoporin
NIPBL Nipped-B homolog (Drosophila)
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR6A1 nuclear receptor subfamily 6, group A, member 1
NSL1 NSL1, MIS12 kinetochore complex component
NXPE3 neurexophilin and PC-esterase domain family, member 3
OTUD1 OTU deubiquitinase 1
P3H4 prolyl 3-hydroxylase family member 4 (non-enzymatic)
PARP10 poly (ADP-ribose) polymerase family, member 10
PAXBP1 PAX3 and PAX7 binding protein 1
PCNXL4 pecanex-like 4 (Drosophila)
PHKA1 phosphorylase kinase, alpha 1 (muscle)
PHLPP2 PH domain and leucine rich repeat protein phosphatase 2
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PQLC2 PQ loop repeat containing 2
PRCC papillary renal cell carcinoma (translocation-associated)
PRR7 proline rich 7 (synaptic)
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
RAB11FIP1 RAB11 family interacting protein 1 (class I)
RAB26 RAB26, member RAS oncogene family
RAB2B RAB2B, member RAS oncogene family
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic)
RANBP2 RAN binding protein 2
RASAL1 RAS protein activator like 1 (GAP1 like)
RASL10B RAS-like, family 10, member B
RBBP7 retinoblastoma binding protein 7
RBMXL1 RNA binding motif protein, X-linked-like 1
RGMB repulsive guidance molecule family member b
RHOB ras homolog family member B
RHOBTB2 Rho-related BTB domain containing 2
RIF1 replication timing regulatory factor 1
RND3 Rho family GTPase 3
RNF138 ring finger protein 138, E3 ubiquitin protein ligase
RPL18A ribosomal protein L18a
RPL26L1 ribosomal protein L26-like 1
RPS10 ribosomal protein S10
RPS18 ribosomal protein S18
SENP7 SUMO1/sentrin specific peptidase 7
SEPT2 septin 2
SFXN1 sideroflexin 1
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
SLC9A6 solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
SLIT1 slit homolog 1 (Drosophila)
SMCHD1 structural maintenance of chromosomes flexible hinge domain containing 1
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SREK1IP1 SREK1-interacting protein 1
SRP9 signal recognition particle 9kDa
SRPR signal recognition particle receptor (docking protein)
SRSF7 serine/arginine-rich splicing factor 7
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa
TMEM109 transmembrane protein 109
TRIM27 tripartite motif containing 27
TSR1 TSR1, 20S rRNA accumulation, homolog (S. cerevisiae)
TTC37 tetratricopeptide repeat domain 37
TUBA1B tubulin, alpha 1b
USO1 USO1 vesicle transport factor
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L2 ZFP36 ring finger protein-like 2
ZMYND8 zinc finger, MYND-type containing 8
ZNF280C zinc finger protein 280C
ZNF30 zinc finger protein 30
ZNF678 zinc finger protein 678
ZXDA zinc finger, X-linked, duplicated A