hsa-miR-489 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 489|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 574442)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-489
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Genes

234 target genes of the hsa-miR-489 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
PNISR PNN-interacting serine/arginine-rich protein 1.45615
RIPK4 receptor-interacting serine-threonine kinase 4 1.45615
OR2W5 olfactory receptor, family 2, subfamily W, member 5 (gene/pseudogene) 1.45615
RBPMS RNA binding protein with multiple splicing 1.45615
FBXO40 F-box protein 40 1.45615
PKP1 plakophilin 1 1.45615
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 1.45615
ANKRD49 ankyrin repeat domain 49 1.45615
UPF3B UPF3 regulator of nonsense transcripts homolog B (yeast) 1.45615
SPTSSA serine palmitoyltransferase, small subunit A 1.26663
PAX3 paired box 3 1.26663
EI24 etoposide induced 2.4 1.26663
ETNK1 ethanolamine kinase 1 1.26663
CRK v-crk avian sarcoma virus CT10 oncogene homolog 1.26663
ZNF639 zinc finger protein 639 1.26663
ACKR4 atypical chemokine receptor 4 1.26663
TMPRSS11E transmembrane protease, serine 11E 1.26663
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 1.11641
TMPRSS11F transmembrane protease, serine 11F 1.11641
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7 1.11641
NF2 neurofibromin 2 (merlin) 1.11641
ZNF618 zinc finger protein 618 1.11641
ZMAT3 zinc finger, matrin-type 3 0.997906
SRSF7 serine/arginine-rich splicing factor 7 0.997906
SMARCA1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 0.90397
UBE2I ubiquitin-conjugating enzyme E2I 0.90397
RAPGEF2 Rap guanine nucleotide exchange factor (GEF) 2 0.90397
PARM1 prostate androgen-regulated mucin-like protein 1 0.90397
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.90397
C14ORF119 chromosome 14 open reading frame 119 0.828473
RNF111 ring finger protein 111 0.828473
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) 0.828473
SRSF1 serine/arginine-rich splicing factor 1 0.828473
FZD3 frizzled class receptor 3 0.766596
TLE4 transducin-like enhancer of split 4 0.766596
HRH4 histamine receptor H4 0.766596
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.766596
RPP14 ribonuclease P/MRP 14kDa subunit 0.714812
GRIK2 glutamate receptor, ionotropic, kainate 2 0.670641
KIAA1715 KIAA1715 0.670641
SEMA6A sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A 0.670641
RBMS3 RNA binding motif, single stranded interacting protein 3 0.670641
ATP5F1 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit B1 0.670641
NRIP1 nuclear receptor interacting protein 1 0.670641
MNS1 meiosis-specific nuclear structural 1 0.632343
PIGR polymeric immunoglobulin receptor 0.632343
HBEGF heparin-binding EGF-like growth factor 0.632343
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.598666
EFNA5 ephrin-A5 0.598666
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21 0.598666
ITPK1 inositol-tetrakisphosphate 1-kinase 0.598666
ATXN7L3B ataxin 7-like 3B 0.598666
LONRF2 LON peptidase N-terminal domain and ring finger 2 0.568687
ZNF24 zinc finger protein 24 0.568687
MAPK14 mitogen-activated protein kinase 14 0.541706
KRT7 keratin 7, type II 0.541706
B4GALT3 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3 0.541706
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.541706
SHC4 SHC (Src homology 2 domain containing) family, member 4 0.517189
NYAP1 neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1 0.517189
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.517189
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.517189
IPO5 importin 5 0.517189
RLIM ring finger protein, LIM domain interacting 0.49473
LIPH lipase, member H 0.49473
ZMYND8 zinc finger, MYND-type containing 8 0.49473
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.49473
KLHL28 kelch-like family member 28 0.474009
NTRK3 neurotrophic tyrosine kinase, receptor, type 3 0.474009
PELI2 pellino E3 ubiquitin protein ligase family member 2 0.474009
VAV3 vav 3 guanine nucleotide exchange factor 0.474009
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.474009
MYO5A myosin VA (heavy chain 12, myoxin) 0.474009
TMEM35 transmembrane protein 35 0.474009
RAB3A RAB3A, member RAS oncogene family 0.454769
MRVI1 murine retrovirus integration site 1 homolog 0.454769
MSN moesin 0.454769
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa 0.454769
LRRC4 leucine rich repeat containing 4 0.436802
RBMS1 RNA binding motif, single stranded interacting protein 1 0.419947
C12ORF42 chromosome 12 open reading frame 42 0.419947
MAP3K2 mitogen-activated protein kinase kinase kinase 2 0.419947
SPATS2L spermatogenesis associated, serine-rich 2-like 0.419947
MTX3 metaxin 3 0.419947
TAOK1 TAO kinase 1 0.419947
ATF7 activating transcription factor 7 0.404082
AHSA2 AHA1, activator of heat shock 90kDa protein ATPase homolog 2 (yeast) 0.404082
GLI3 GLI family zinc finger 3 0.389112
TLK1 tousled-like kinase 1 0.389112
IMPACT impact RWD domain protein 0.389112
GLIPR2 GLI pathogenesis-related 2 0.389112
CISD2 CDGSH iron sulfur domain 2 0.389112
MVB12B multivesicular body subunit 12B 0.37496
COQ10B coenzyme Q10 homolog B (S. cerevisiae) 0.37496
NPEPPS aminopeptidase puromycin sensitive 0.37496
MAPRE2 microtubule-associated protein, RP/EB family, member 2 0.37496
MAPKAP1 mitogen-activated protein kinase associated protein 1 0.37496
SYTL5 synaptotagmin-like 5 0.361556
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae) 0.361556
AKIRIN2 akirin 2 0.361556
CELF2 CUGBP, Elav-like family member 2 0.361556
ZAK sterile alpha motif and leucine zipper containing kinase AZK 0.361556
CEP41 centrosomal protein 41kDa 0.361556
CXORF40A chromosome X open reading frame 40A 0.361556
MYCBP2 MYC binding protein 2, E3 ubiquitin protein ligase 0.348832
SNN stannin 0.336728
GLDN gliomedin 0.336728
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.336728
KIAA1549 KIAA1549 0.336728
FRMD4A FERM domain containing 4A 0.32519
RIC8B RIC8 guanine nucleotide exchange factor B 0.32519
BEND4 BEN domain containing 4 0.32519
SUSD6 sushi domain containing 6 0.32519
TRIL TLR4 interactor with leucine-rich repeats 0.31417
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 0.303626
SLC41A1 solute carrier family 41 (magnesium transporter), member 1 0.303626
CAPN5 calpain 5 0.303626
PITX2 paired-like homeodomain 2 0.303626
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.303626
HDAC2 histone deacetylase 2 0.303626
PCBP1 poly(rC) binding protein 1 0.293524
BIRC6 baculoviral IAP repeat containing 6 0.293524
LURAP1 leucine rich adaptor protein 1 0.293524
SMC1A structural maintenance of chromosomes 1A 0.293524
PACRG PARK2 co-regulated 0.283838
SMURF1 SMAD specific E3 ubiquitin protein ligase 1 0.283838
ZCCHC14 zinc finger, CCHC domain containing 14 0.283838
FNDC5 fibronectin type III domain containing 5 0.274552
DLX1 distal-less homeobox 1 0.248923
UBE2W ubiquitin-conjugating enzyme E2W (putative) 0.248923
TEX38 testis expressed 38 0.248923
JADE1 jade family PHD finger 1 0.248923
RIC3 RIC3 acetylcholine receptor chaperone 0.241055
TIMP2 TIMP metallopeptidase inhibitor 2 0.23348
TMEM260 transmembrane protein 260 0.219115
LARP1B La ribonucleoprotein domain family, member 1B 0.219115
KCNJ12 potassium channel, inwardly rectifying subfamily J, member 12 0.219115
SORL1 sortilin-related receptor, L(DLR class) A repeats containing 0.212286
DIAPH1 diaphanous-related formin 1 0.212286
SBNO1 strawberry notch homolog 1 (Drosophila) 0.212286
CHD1 chromodomain helicase DNA binding protein 1 0.212286
COCH cochlin 0.212286
KLHL29 kelch-like family member 29 0.205675
GLIS3 GLIS family zinc finger 3 0.205675
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.199275
TSC1 tuberous sclerosis 1 0.199275
KANK4 KN motif and ankyrin repeat domains 4 0.193083
MATR3 matrin 3 0.193083
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.193083
USP48 ubiquitin specific peptidase 48 0.187098
STRN striatin, calmodulin binding protein 0.187098
COPS2 COP9 signalosome subunit 2 0.175726
MFAP3L microfibrillar-associated protein 3-like 0.17031
EYA1 EYA transcriptional coactivator and phosphatase 1 0.17031
GOSR2 golgi SNAP receptor complex member 2 0.165047
CSNK1G1 casein kinase 1, gamma 1 0.159923
KIF5C kinesin family member 5C 0.159923
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 0.159923
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.159923
TPM4 tropomyosin 4 0.159923
EFR3A EFR3 homolog A (S. cerevisiae) 0.154935
ZNF148 zinc finger protein 148 0.15008
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.15008
PGP phosphoglycolate phosphatase 0.15008
SZRD1 SUZ RNA binding domain containing 1 0.145356
IPO7 importin 7 0.145356
KLHL32 kelch-like family member 32 0.145356
VMA21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) 0.140752
PAX6 paired box 6 0.140752
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.140752
CLOCK clock circadian regulator 0.136254
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing 0.136254
ATP2A3 ATPase, Ca++ transporting, ubiquitous 0.127531
USP4 ubiquitin specific peptidase 4 (proto-oncogene) 0.127531
TLR4 toll-like receptor 4 0.127531
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.123298
TMEM64 transmembrane protein 64 0.123298
KLF3 Kruppel-like factor 3 (basic) 0.119151
ACVR1C activin A receptor, type IC 0.119151
INSR insulin receptor 0.115091
CDC73 cell division cycle 73 0.107229
LHX6 LIM homeobox 6 0.107229
AEBP2 AE binding protein 2 0.107229
STC2 stanniocalcin 2 0.107229
SMAD3 SMAD family member 3 0.103424
TMEM106B transmembrane protein 106B 0.099701
ATXN3 ataxin 3 0.09606
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) 0.092495
SCN2A sodium channel, voltage gated, type II alpha subunit 0.092495
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C 0.088999
ATRN attractin 0.085563
BDNF brain-derived neurotrophic factor 0.082179
PRICKLE2 prickle homolog 2 (Drosophila) 0.082179
FBXW7 F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase 0.082179
E2F7 E2F transcription factor 7 0.078844
MMP2 matrix metallopeptidase 2 0.075559
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.075559
SPIN1 spindlin 1 0.065994
SLC7A6 solute carrier family 7 (amino acid transporter light chain, y+L system), member 6 0.065994
CTDSPL2 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2 0.062888
SYT14 synaptotagmin XIV 0.062888
LIN7C lin-7 homolog C (C. elegans) 0.059817
CLCN5 chloride channel, voltage-sensitive 5 0.059817
DSEL dermatan sulfate epimerase-like 0.059817
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1 0.045136
CBX5 chromobox homolog 5 0.045136
PHC3 polyhomeotic homolog 3 (Drosophila) 0.045136
CLDN16 claudin 16 0.042355
KPNA6 karyopherin alpha 6 (importin alpha 7) 0.042355
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae) 0.039622
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E 0.03694
DCC DCC netrin 1 receptor 0.034317
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 0.034317
C5ORF24 chromosome 5 open reading frame 24 0.029271
FAM84A family with sequence similarity 84, member A 0.026857
SOX12 SRY (sex determining region Y)-box 12 0.02452
AADACL3 arylacetamide deacetylase-like 3 0.02452
C16ORF72 chromosome 16 open reading frame 72 0.02452
USP46 ubiquitin specific peptidase 46 0.020071
DGKE diacylglycerol kinase, epsilon 64kDa 0.017945
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.015875
CLMN calmin (calponin-like, transmembrane) 0.015875
AGPS alkylglycerone phosphate synthase 0.015875
KIAA1324L KIAA1324-like 0.015875
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.013856
DNM3 dynamin 3 0.011888
LCOR ligand dependent nuclear receptor corepressor 0.009975
OPCML opioid binding protein/cell adhesion molecule-like 0.008128
PAIP2B poly(A) binding protein interacting protein 2B 0.008128
RORA RAR-related orphan receptor A 0.008128
AKT3 v-akt murine thymoma viral oncogene homolog 3 0.006367
PRTG protogenin 0.006367
TRIQK triple QxxK/R motif containing 0.004732
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) 0.002088