hsa-miR-581 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 581|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 693166)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-581
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Genes

142 target genes of the hsa-miR-581 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
SMAD7 SMAD family member 7 1.45615
AGFG1 ArfGAP with FG repeats 1 1.45615
OVGP1 oviductal glycoprotein 1, 120kDa 1.45615
DMRT3 doublesex and mab-3 related transcription factor 3 1.26663
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.26663
LPP LIM domain containing preferred translocation partner in lipoma 1.26663
UBP1 upstream binding protein 1 (LBP-1a) 1.26663
RBM15 RNA binding motif protein 15 1.26663
TMEM154 transmembrane protein 154 1.11641
KCNJ8 potassium channel, inwardly rectifying subfamily J, member 8 1.11641
DNAJC13 DnaJ (Hsp40) homolog, subfamily C, member 13 1.11641
NR2C1 nuclear receptor subfamily 2, group C, member 1 1.11641
SON SON DNA binding protein 1.11641
FOXO1 forkhead box O1 0.997906
PER2 period circadian clock 2 0.90397
SPAST spastin 0.90397
DSCAM Down syndrome cell adhesion molecule 0.828473
GJB7 gap junction protein, beta 7, 25kDa 0.828473
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.828473
MEF2A myocyte enhancer factor 2A 0.828473
PHGR1 proline/histidine/glycine-rich 1 0.766596
FOXO3 forkhead box O3 0.766596
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.766596
SENP2 SUMO1/sentrin/SMT3 specific peptidase 2 0.714812
ARHGEF6 Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6 0.670641
TENM1 teneurin transmembrane protein 1 0.670641
EDEM1 ER degradation enhancer, mannosidase alpha-like 1 0.632343
ZNF322 zinc finger protein 322 0.632343
RFWD3 ring finger and WD repeat domain 3 0.598666
PTPRD protein tyrosine phosphatase, receptor type, D 0.598666
DIRAS2 DIRAS family, GTP-binding RAS-like 2 0.598666
PDRG1 p53 and DNA-damage regulated 1 0.568687
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 0.568687
CBFA2T3 core-binding factor, runt domain, alpha subunit 2; translocated to, 3 0.541706
PRICKLE2 prickle homolog 2 (Drosophila) 0.517189
GEMIN5 gem (nuclear organelle) associated protein 5 0.517189
SPON1 spondin 1, extracellular matrix protein 0.474009
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.474009
ADAMTS19 ADAM metallopeptidase with thrombospondin type 1 motif, 19 0.454769
YIPF5 Yip1 domain family, member 5 0.436802
TOX4 TOX high mobility group box family member 4 0.436802
LHFPL2 lipoma HMGIC fusion partner-like 2 0.436802
CREBL2 cAMP responsive element binding protein-like 2 0.419947
TUB tubby bipartite transcription factor 0.419947
ZFP90 ZFP90 zinc finger protein 0.419947
STX16 syntaxin 16 0.419947
IMPAD1 inositol monophosphatase domain containing 1 0.419947
HIPK3 homeodomain interacting protein kinase 3 0.404082
SYNPO2L synaptopodin 2-like 0.404082
CISD3 CDGSH iron sulfur domain 3 0.404082
ANKRD13C ankyrin repeat domain 13C 0.404082
PCDH9 protocadherin 9 0.389112
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3 0.37496
TSHZ2 teashirt zinc finger homeobox 2 0.37496
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.361556
CERS6 ceramide synthase 6 0.361556
USP34 ubiquitin specific peptidase 34 0.361556
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma) 0.348832
BTG1 B-cell translocation gene 1, anti-proliferative 0.348832
SYNM synemin, intermediate filament protein 0.336728
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.32519
MFAP1 microfibrillar-associated protein 1 0.32519
ZBTB11 zinc finger and BTB domain containing 11 0.32519
LRRFIP2 leucine rich repeat (in FLII) interacting protein 2 0.32519
ERRFI1 ERBB receptor feedback inhibitor 1 0.31417
FAM117B family with sequence similarity 117, member B 0.31417
MED19 mediator complex subunit 19 0.303626
TDP1 tyrosyl-DNA phosphodiesterase 1 0.293524
WNT2B wingless-type MMTV integration site family, member 2B 0.293524
RORA RAR-related orphan receptor A 0.283838
DICER1 dicer 1, ribonuclease type III 0.274552
ZRANB2 zinc finger, RAN-binding domain containing 2 0.274552
KCTD16 potassium channel tetramerization domain containing 16 0.248923
EHD1 EH-domain containing 1 0.241055
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6 0.226173
TTC30A tetratricopeptide repeat domain 30A 0.219115
SLC16A6 solute carrier family 16, member 6 0.219115
PBX2 pre-B-cell leukemia homeobox 2 0.219115
FAT2 FAT atypical cadherin 2 0.219115
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.205675
LIN28A lin-28 homolog A (C. elegans) 0.199275
NUFIP2 nuclear fragile X mental retardation protein interacting protein 2 0.187098
GLCE glucuronic acid epimerase 0.187098
SOCS3 suppressor of cytokine signaling 3 0.187098
CSRNP3 cysteine-serine-rich nuclear protein 3 0.187098
SNX19 sorting nexin 19 0.17031
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 0.17031
UBN2 ubinuclein 2 0.159923
RABEP1 rabaptin, RAB GTPase binding effector protein 1 0.154935
SETBP1 SET binding protein 1 0.15008
ZNF827 zinc finger protein 827 0.145356
SSH1 slingshot protein phosphatase 1 0.145356
KPNA4 karyopherin alpha 4 (importin alpha 3) 0.145356
ANO5 anoctamin 5 0.140752
PELI3 pellino E3 ubiquitin protein ligase family member 3 0.136254
GLG1 golgi glycoprotein 1 0.127531
HNRNPUL1 heterogeneous nuclear ribonucleoprotein U-like 1 0.127531
PTPN11 protein tyrosine phosphatase, non-receptor type 11 0.127531
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit 0.123298
HIPK2 homeodomain interacting protein kinase 2 0.119151
KDM6B lysine (K)-specific demethylase 6B 0.115091
CBX7 chromobox homolog 7 0.111118
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.107229
YPEL2 yippee-like 2 (Drosophila) 0.103424
ABCG4 ATP-binding cassette, sub-family G (WHITE), member 4 0.103424
RALGPS1 Ral GEF with PH domain and SH3 binding motif 1 0.103424
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.099701
ITGA10 integrin, alpha 10 0.099701
CNTD1 cyclin N-terminal domain containing 1 0.09606
ADCY5 adenylate cyclase 5 0.09606
PDZD4 PDZ domain containing 4 0.09606
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.09606
CSNK1G1 casein kinase 1, gamma 1 0.092495
SLC25A53 solute carrier family 25, member 53 0.085563
CUX1 cut-like homeobox 1 0.085563
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.085563
ZNFX1 zinc finger, NFX1-type containing 1 0.085563
PHIP pleckstrin homology domain interacting protein 0.075559
EPT1 ethanolaminephosphotransferase 1 0.072324
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 0.069137
MGA MGA, MAX dimerization protein 0.069137
DHDDS dehydrodolichyl diphosphate synthase 0.065994
TK2 thymidine kinase 2, mitochondrial 0.065994
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 0.059817
EAF1 ELL associated factor 1 0.059817
LIMD1 LIM domains containing 1 0.059817
CPPED1 calcineurin-like phosphoesterase domain containing 1 0.056784
MBNL3 muscleblind-like splicing regulator 3 0.053794
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.047969
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.045136
PLEKHM3 pleckstrin homology domain containing, family M, member 3 0.042355
CA5B carbonic anhydrase VB, mitochondrial 0.03694
GNA13 guanine nucleotide binding protein (G protein), alpha 13 0.034317
THRB thyroid hormone receptor, beta 0.02452
AGO1 argonaute RISC catalytic component 1 0.02452
COL19A1 collagen, type XIX, alpha 1 0.02452
EXD2 exonuclease 3'-5' domain containing 2 0.017945
NOS1 nitric oxide synthase 1 (neuronal) 0.013856
ANTXR2 anthrax toxin receptor 2 0.011888
PAX6 paired box 6 0.008128
CELF2 CUGBP, Elav-like family member 2 0.003282
ILDR2 immunoglobulin-like domain containing receptor 2 0.002088