hsa-miR-591 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 591|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 693176)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-591
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Genes

135 target genes of the hsa-miR-591 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
POLI polymerase (DNA directed) iota 1.45615
CCDC43 coiled-coil domain containing 43 1.45615
PCDH7 protocadherin 7 1.45615
THBS2 thrombospondin 2 1.45615
VPS26A vacuolar protein sorting 26 homolog A (S. pombe) 1.45615
GABRA2 gamma-aminobutyric acid (GABA) A receptor, alpha 2 1.45615
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 1.26663
PRR14L proline rich 14-like 1.26663
PIH1D3 PIH1 domain containing 3 1.26663
ZBTB44 zinc finger and BTB domain containing 44 1.26663
MEX3B mex-3 RNA binding family member B 1.26663
PFKM phosphofructokinase, muscle 1.11641
KIAA1324L KIAA1324-like 1.11641
SRF serum response factor (c-fos serum response element-binding transcription factor) 0.997906
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.997906
KCNK15 potassium channel, two pore domain subfamily K, member 15 0.997906
CCNL1 cyclin L1 0.997906
LIMCH1 LIM and calponin homology domains 1 0.997906
MEGF11 multiple EGF-like-domains 11 0.997906
TMEM167B transmembrane protein 167B 0.997906
CCNJ cyclin J 0.997906
GOSR1 golgi SNAP receptor complex member 1 0.90397
EPHA8 EPH receptor A8 0.90397
CAMK2D calcium/calmodulin-dependent protein kinase II delta 0.90397
ZEB1 zinc finger E-box binding homeobox 1 0.828473
ARHGAP35 Rho GTPase activating protein 35 0.828473
RRAD Ras-related associated with diabetes 0.828473
SERBP1 SERPINE1 mRNA binding protein 1 0.766596
CPNE3 copine III 0.766596
ALG6 ALG6, alpha-1,3-glucosyltransferase 0.766596
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group) 0.766596
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides 0.766596
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2 0.714812
RANBP9 RAN binding protein 9 0.714812
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 0.714812
RBM18 RNA binding motif protein 18 0.670641
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 0.670641
NRG2 neuregulin 2 0.632343
FOXA1 forkhead box A1 0.632343
PAXBP1 PAX3 and PAX7 binding protein 1 0.598666
OSBPL9 oxysterol binding protein-like 9 0.568687
BNC2 basonuclin 2 0.568687
RBPMS RNA binding protein with multiple splicing 0.517189
SELPLG selectin P ligand 0.517189
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.517189
RSF1 remodeling and spacing factor 1 0.517189
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.49473
SNRK SNF related kinase 0.49473
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.49473
REM2 RAS (RAD and GEM)-like GTP binding 2 0.474009
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.474009
TUBB2B tubulin, beta 2B class IIb 0.454769
BCLAF1 BCL2-associated transcription factor 1 0.454769
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.454769
FBXO11 F-box protein 11 0.454769
ARF1 ADP-ribosylation factor 1 0.454769
TTC19 tetratricopeptide repeat domain 19 0.454769
CCER1 coiled-coil glutamate-rich protein 1 0.454769
MCFD2 multiple coagulation factor deficiency 2 0.436802
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H 0.436802
MOCS1 molybdenum cofactor synthesis 1 0.436802
SETBP1 SET binding protein 1 0.436802
TCF4 transcription factor 4 0.419947
FBXO45 F-box protein 45 0.419947
ARHGAP12 Rho GTPase activating protein 12 0.419947
CLIP3 CAP-GLY domain containing linker protein 3 0.419947
PTPRE protein tyrosine phosphatase, receptor type, E 0.404082
KCNH4 potassium channel, voltage gated eag related subfamily H, member 4 0.404082
IRS1 insulin receptor substrate 1 0.389112
NEGR1 neuronal growth regulator 1 0.37496
CACNG3 calcium channel, voltage-dependent, gamma subunit 3 0.37496
N4BP2L1 NEDD4 binding protein 2-like 1 0.37496
C9ORF69 chromosome 9 open reading frame 69 0.37496
DENND6A DENN/MADD domain containing 6A 0.361556
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 0.361556
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 0.361556
LHX1 LIM homeobox 1 0.361556
RAB1A RAB1A, member RAS oncogene family 0.336728
TMED1 transmembrane emp24 protein transport domain containing 1 0.336728
FGD6 FYVE, RhoGEF and PH domain containing 6 0.32519
QKI QKI, KH domain containing, RNA binding 0.32519
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.303626
BMP2 bone morphogenetic protein 2 0.303626
PRDM12 PR domain containing 12 0.303626
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.293524
SCNN1G sodium channel, non voltage gated 1 gamma subunit 0.274552
PAX2 paired box 2 0.274552
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein 0.265648
PURA purine-rich element binding protein A 0.265648
AREL1 apoptosis resistant E3 ubiquitin protein ligase 1 0.257113
PCNX pecanex homolog (Drosophila) 0.241055
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.23348
EML1 echinoderm microtubule associated protein like 1 0.226173
RBM20 RNA binding motif protein 20 0.226173
EXOC5 exocyst complex component 5 0.226173
KLF3 Kruppel-like factor 3 (basic) 0.212286
NOL4L nucleolar protein 4-like 0.212286
DTNB dystrobrevin, beta 0.212286
B3GNT5 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 0.199275
ANKRD12 ankyrin repeat domain 12 0.193083
TMEM248 transmembrane protein 248 0.193083
GLUD1 glutamate dehydrogenase 1 0.181316
C16ORF72 chromosome 16 open reading frame 72 0.154935
LRRC59 leucine rich repeat containing 59 0.131849
STIP1 stress-induced phosphoprotein 1 0.131849
SYNPO2 synaptopodin 2 0.127531
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.127531
NUDT4 nudix (nucleoside diphosphate linked moiety X)-type motif 4 0.127531
TRMT61A tRNA methyltransferase 61A 0.127531
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha 0.119151
CREBZF CREB/ATF bZIP transcription factor 0.111118
ST5 suppression of tumorigenicity 5 0.107229
BTG1 B-cell translocation gene 1, anti-proliferative 0.09606
ZC3H12B zinc finger CCCH-type containing 12B 0.092495
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.092495
RBMS3 RNA binding motif, single stranded interacting protein 3 0.085563
NCOA7 nuclear receptor coactivator 7 0.082179
SLAIN2 SLAIN motif family, member 2 0.078844
SYT11 synaptotagmin XI 0.078844
EHF ets homologous factor 0.075559
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2 0.072324
ABLIM2 actin binding LIM protein family, member 2 0.065994
TAOK1 TAO kinase 1 0.062888
ZNF385A zinc finger protein 385A 0.059817
FZD4 frizzled class receptor 4 0.059817
DCAF7 DDB1 and CUL4 associated factor 7 0.050854
DLGAP2 discs, large (Drosophila) homolog-associated protein 2 0.047969
KIAA1671 KIAA1671 0.042355
DDHD1 DDHD domain containing 1 0.042355
AAK1 AP2 associated kinase 1 0.039622
CMIP c-Maf inducing protein 0.031759
XPO4 exportin 4 0.017945
GPR26 G protein-coupled receptor 26 0.015875
CPLX2 complexin 2 0.004732
MAVS mitochondrial antiviral signaling protein 0.002088