hsa-miR-611 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 611|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 693196)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-611
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10 target genes of the hsa-miR-611 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
MEF2D myocyte enhancer factor 2D 1.45615
SEMA6C sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C 1.11641
TMEM119 transmembrane protein 119 0.997906
GTDC1 glycosyltransferase-like domain containing 1 0.541706
RIMBP2 RIMS binding protein 2 0.517189
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.49473
TRAF3 TNF receptor-associated factor 3 0.274552
SYN1 synapsin I 0.23348
EIF4G1 eukaryotic translation initiation factor 4 gamma, 1 0.127531
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 0.009975