hsa-miR-639 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 639|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 693224)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-639
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16 target genes of the hsa-miR-639 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
KANSL1 KAT8 regulatory NSL complex subunit 1 1.26663
TBR1 T-box, brain, 1 1.26663
CACNG7 calcium channel, voltage-dependent, gamma subunit 7 0.517189
PKNOX1 PBX/knotted 1 homeobox 1 0.474009
QKI QKI, KH domain containing, RNA binding 0.474009
ITPRIP inositol 1,4,5-trisphosphate receptor interacting protein 0.436802
POU2F2 POU class 2 homeobox 2 0.389112
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 0.336728
SLC35F5 solute carrier family 35, member F5 0.293524
IRX1 iroquois homeobox 1 0.248923
MSI1 musashi RNA-binding protein 1 0.23348
AAK1 AP2 associated kinase 1 0.193083
DYNLL2 dynein, light chain, LC8-type 2 0.187098
KAT7 K(lysine) acetyltransferase 7 0.123298
CREBRF CREB3 regulatory factor 0.082179
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2 0.059817