hsa-miR-744 Gene Set

Dataset TargetScan Predicted Conserved microRNA Targets
Category genomics
Type microRNA
Description microRNA 744|microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 100126313)
External Link http://www.targetscan.org/cgi-bin/targetscan/vert_70/targetscan.cgi?mirg=hsa-miR-744
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Genes

30 target genes of the hsa-miR-744 microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

Symbol Name Standardized Value
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3 1.26663
SPTBN4 spectrin, beta, non-erythrocytic 4 0.766596
UNC5A unc-5 homolog A (C. elegans) 0.714812
ZNF385A zinc finger protein 385A 0.670641
LRP3 low density lipoprotein receptor-related protein 3 0.632343
TMEM253 transmembrane protein 253 0.598666
VPS37D vacuolar protein sorting 37 homolog D (S. cerevisiae) 0.541706
KCNAB3 potassium channel, voltage gated subfamily A regulatory beta subunit 3 0.49473
CYTH2 cytohesin 2 0.474009
PODXL2 podocalyxin-like 2 0.389112
ZNF827 zinc finger protein 827 0.31417
CSMD2 CUB and Sushi multiple domains 2 0.303626
HOXB8 homeobox B8 0.293524
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.293524
UBE2L3 ubiquitin-conjugating enzyme E2L 3 0.23348
PHLDB3 pleckstrin homology-like domain, family B, member 3 0.219115
CYP4F22 cytochrome P450, family 4, subfamily F, polypeptide 22 0.17031
JUNB jun B proto-oncogene 0.15008
NPAS4 neuronal PAS domain protein 4 0.140752
RARA retinoic acid receptor, alpha 0.09606
NRGN neurogranin (protein kinase C substrate, RC3) 0.092495
LINC01465 long intergenic non-protein coding RNA 1465 0.078844
CAMK2N2 calcium/calmodulin-dependent protein kinase II inhibitor 2 0.075559
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 0.069137
TGFB1 transforming growth factor, beta 1 0.053794
KLC2 kinesin light chain 2 0.047969
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.045136
SLC25A35 solute carrier family 25, member 35 0.029271
SEC14L2 SEC14-like 2 (S. cerevisiae) 0.02452
PAX2 paired box 2 0.003282