hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations
Category transcriptomics
Type transcription factor perturbation
Description transcription factor perturbation identified as [TF gene symbol]_[publication PMID]_[cell or tissue]_[perturbation]_[organism]_[GEO platform]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE41005
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Genes

656 genes differentially expressed following the hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005 transcription factor perturbation from the GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations dataset.

increased expression

Symbol Name Standardized Value
USP6NL USP6 N-terminal like 0.218364
EPC1 enhancer of polycomb homolog 1 (Drosophila) 0.218214
MEGF11 multiple EGF-like-domains 11 0.217315
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like) 0.216694
KIF3B kinesin family member 3B 0.21492
PTPRG protein tyrosine phosphatase, receptor type, G 0.214326
TMEM134 transmembrane protein 134 0.212945
PIGU phosphatidylinositol glycan anchor biosynthesis, class U 0.212439
CD83 CD83 molecule 0.212004
HAGHL hydroxyacylglutathione hydrolase-like 0.211696
FBXL20 F-box and leucine-rich repeat protein 20 0.210111
WDR37 WD repeat domain 37 0.209656
NDFIP2 Nedd4 family interacting protein 2 0.209257
KCNQ1OT1 KCNQ1 opposite strand/antisense transcript 1 (non-protein coding) 0.209186
CILP2 cartilage intermediate layer protein 2 0.207922
CDK19 cyclin-dependent kinase 19 0.20663
GSE1 Gse1 coiled-coil protein 0.205161
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.201868
ERBB2IP erbb2 interacting protein 0.201796
ENY2 enhancer of yellow 2 homolog (Drosophila) 0.198763
ZCCHC11 zinc finger, CCHC domain containing 11 0.196078
CTPS2 CTP synthase 2 0.196078
CCNDBP1 cyclin D-type binding-protein 1 0.195795
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 0.195319
EMC2 ER membrane protein complex subunit 2 0.194234
SCARNA13 small Cajal body-specific RNA 13 0.192857
NCALD neurocalcin delta 0.192158
SYNE1 spectrin repeat containing, nuclear envelope 1 0.190867
CSNK2A2 casein kinase 2, alpha prime polypeptide 0.1897
CD47 CD47 molecule 0.189178
IRF2 interferon regulatory factor 2 0.188533
KAT2B K(lysine) acetyltransferase 2B 0.188472
DPF2 D4, zinc and double PHD fingers family 2 0.18702
ARHGAP39 Rho GTPase activating protein 39 0.186793
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 0.186054
PHOX2B paired-like homeobox 2b 0.18471
MED13 mediator complex subunit 13 0.183018
ATP11B ATPase, class VI, type 11B 0.181576
BMPR1B bone morphogenetic protein receptor, type IB 0.1815
DGAT1 diacylglycerol O-acyltransferase 1 0.180934
PHF13 PHD finger protein 13 0.180043
DNAJC14 DnaJ (Hsp40) homolog, subfamily C, member 14 0.179675
DGUOK deoxyguanosine kinase 0.178099
CBWD1 COBW domain containing 1 0.176946
BIN1 bridging integrator 1 0.176636
MEDAG mesenteric estrogen-dependent adipogenesis 0.173803
GABARAPL1 GABA(A) receptor-associated protein like 1 0.17166
DGKA diacylglycerol kinase, alpha 80kDa 0.170592
SFMBT2 Scm-like with four mbt domains 2 0.169318
PKD1 polycystic kidney disease 1 (autosomal dominant) 0.169037
POLG polymerase (DNA directed), gamma 0.167044
ITGA1 integrin, alpha 1 0.165234
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.163982
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated) 0.161842
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta 0.161842
DPEP3 dipeptidase 3 0.160302
NIPAL1 NIPA-like domain containing 1 0.159957
CHSY3 chondroitin sulfate synthase 3 0.15919
HNRNPUL2 heterogeneous nuclear ribonucleoprotein U-like 2 0.15905
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.158737
CDC42SE2 CDC42 small effector 2 0.158565
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10 0.158219
CARD6 caspase recruitment domain family, member 6 0.157021
SPO11 SPO11 meiotic protein covalently bound to DSB 0.156188
PTAFR platelet-activating factor receptor 0.155984
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.15462
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3 0.152978
CD4 CD4 molecule 0.152285
FAM160A2 family with sequence similarity 160, member A2 0.152238
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 0.150746
BLOC1S6 biogenesis of lysosomal organelles complex-1, subunit 6, pallidin 0.150461
FAM63B family with sequence similarity 63, member B 0.149229
PHYHD1 phytanoyl-CoA dioxygenase domain containing 1 0.147905
MAP3K11 mitogen-activated protein kinase kinase kinase 11 0.14756
KLHL10 kelch-like family member 10 0.146726
DGKQ diacylglycerol kinase, theta 110kDa 0.145667
ACER1 alkaline ceramidase 1 0.144373
RTP4 receptor (chemosensory) transporter protein 4 0.144027
DIDO1 death inducer-obliterator 1 0.143053
CASQ2 calsequestrin 2 (cardiac muscle) 0.142547
MED22 mediator complex subunit 22 0.141016
IKBKB inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta 0.138497
CMKLR1 chemerin chemokine-like receptor 1 0.138007
INPP1 inositol polyphosphate-1-phosphatase 0.136056
LPAR6 lysophosphatidic acid receptor 6 0.135867
FAAH fatty acid amide hydrolase 0.135114
WARS tryptophanyl-tRNA synthetase 0.131687
NPEPPS aminopeptidase puromycin sensitive 0.130996
TCTEX1D2 Tctex1 domain containing 2 0.128346
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2 0.128346
TG thyroglobulin 0.127689
DYNC2LI1 dynein, cytoplasmic 2, light intermediate chain 1 0.12595
GSTM1 glutathione S-transferase mu 1 0.1257
KIAA1551 KIAA1551 0.12456
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.124327
ERC1 ELKS/RAB6-interacting/CAST family member 1 0.123032
LIMK2 LIM domain kinase 2 0.122688
SRRM4 serine/arginine repetitive matrix 4 0.122096
HRSP12 heat-responsive protein 12 0.121519
WRAP73 WD repeat containing, antisense to TP73 0.120726
VCAN versican 0.120586
RPL41 ribosomal protein L41 0.120509
STAT2 signal transducer and activator of transcription 2, 113kDa 0.118722
ACTN1 actinin, alpha 1 0.118613
SLC26A11 solute carrier family 26 (anion exchanger), member 11 0.11807
LATS2 large tumor suppressor kinase 2 0.117202
DHCR24 24-dehydrocholesterol reductase 0.116552
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.116135
HSDL1 hydroxysteroid dehydrogenase like 1 0.111383
HIST1H2BH histone cluster 1, H2bh 0.111244
ADD3 adducin 3 (gamma) 0.110353
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 0.110046
FAM65B family with sequence similarity 65, member B 0.109402
SEPT6 septin 6 0.109402
ZNF207 zinc finger protein 207 0.107305
GIMAP8 GTPase, IMAP family member 8 0.105475
RASA1 RAS p21 protein activator (GTPase activating protein) 1 0.104227
CARD11 caspase recruitment domain family, member 11 0.103376
ZMYND8 zinc finger, MYND-type containing 8 0.102966
SLC44A2 solute carrier family 44 (choline transporter), member 2 0.102027
IFT80 intraflagellar transport 80 0.100983
HEATR5B HEAT repeat containing 5B 0.099745
SLBP stem-loop binding protein 0.099006
GIMAP6 GTPase, IMAP family member 6 0.098946
MYO1F myosin IF 0.097518
POLDIP3 polymerase (DNA-directed), delta interacting protein 3 0.097143
CPM carboxypeptidase M 0.096917
TGFBR3 transforming growth factor, beta receptor III 0.096812
RPL22 ribosomal protein L22 0.095749
C12ORF57 chromosome 12 open reading frame 57 0.095449
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7 0.093822
EXT2 exostosin glycosyltransferase 2 0.091443
GPX4 glutathione peroxidase 4 0.090851
SNW1 SNW domain containing 1 0.090599
RNF167 ring finger protein 167 0.089416
HBP1 HMG-box transcription factor 1 0.088134
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.087193
COL20A1 collagen, type XX, alpha 1 0.085756
FRAT1 frequently rearranged in advanced T-cell lymphomas 1 0.085331
LY6D lymphocyte antigen 6 complex, locus D 0.084718
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.083362
PRRX1 paired related homeobox 1 0.082127
RASA3 RAS p21 protein activator 3 0.08172
LBH limb bud and heart development 0.080852
KRTAP4-1 keratin associated protein 4-1 0.079048
CD96 CD96 molecule 0.07899
SDCBP syndecan binding protein (syntenin) 0.078731
MDC1 mediator of DNA-damage checkpoint 1 0.078357
ANTXR2 anthrax toxin receptor 2 0.078286
C19ORF12 chromosome 19 open reading frame 12 0.077998
ACAD9 acyl-CoA dehydrogenase family, member 9 0.077812
TRIP12 thyroid hormone receptor interactor 12 0.076637
HECA headcase homolog (Drosophila) 0.076279
MGST3 microsomal glutathione S-transferase 3 0.076093
MAU2 MAU2 sister chromatid cohesion factor 0.074568
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8 0.071424
LIMA1 LIM domain and actin binding 1 0.071029
PAIP2 poly(A) binding protein interacting protein 2 0.066301
ANAPC11 anaphase promoting complex subunit 11 0.065537
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4 0.065108
ATAT1 alpha tubulin acetyltransferase 1 0.064403
PHF3 PHD finger protein 3 0.062077
PMPCA peptidase (mitochondrial processing) alpha 0.061953
CABP2 calcium binding protein 2 0.061707
LIPA lipase A, lysosomal acid, cholesterol esterase 0.059674
ARRDC4 arrestin domain containing 4 0.059021
RAP2C RAP2C, member of RAS oncogene family 0.058776
S1PR3 sphingosine-1-phosphate receptor 3 0.058749
HNRNPA1 heterogeneous nuclear ribonucleoprotein A1 0.057126
USP11 ubiquitin specific peptidase 11 0.056021
PTGES prostaglandin E synthase 0.055537
GMPPA GDP-mannose pyrophosphorylase A 0.055362
TBC1D9B TBC1 domain family, member 9B (with GRAM domain) 0.0548
ZMYM5 zinc finger, MYM-type 5 0.054025
KDM7A lysine (K)-specific demethylase 7A 0.053166
ZNF726 zinc finger protein 726 0.051809
KLHL24 kelch-like family member 24 0.050489
RNF141 ring finger protein 141 0.050314
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.049758
RGS3 regulator of G-protein signaling 3 0.048388
DTX4 deltex 4, E3 ubiquitin ligase 0.04801
RNPC3 RNA-binding region (RNP1, RRM) containing 3 0.047982
IL16 interleukin 16 0.047315
MAPK14 mitogen-activated protein kinase 14 0.047084
RPLP0 ribosomal protein, large, P0 0.046795
SCML4 sex comb on midleg-like 4 (Drosophila) 0.046591
PSME4 proteasome (prosome, macropain) activator subunit 4 0.046477
STX5 syntaxin 5 0.045065
SLA Src-like-adaptor 0.044178
ZNF740 zinc finger protein 740 0.043463
TRIM33 tripartite motif containing 33 0.042805
CPT2 carnitine palmitoyltransferase 2 0.042805
CTSE cathepsin E 0.04235
RERE arginine-glutamic acid dipeptide (RE) repeats 0.041386
IFNGR1 interferon gamma receptor 1 0.039804
ITM2B integral membrane protein 2B 0.039721
KDM1A lysine (K)-specific demethylase 1A 0.039608
SELP selectin P (granule membrane protein 140kDa, antigen CD62) 0.038681
ZNRF2 zinc and ring finger 2, E3 ubiquitin protein ligase 0.036532
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 0.036171
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.035949
UBE2I ubiquitin-conjugating enzyme E2I 0.035672
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6 0.035341
MPRIP myosin phosphatase Rho interacting protein 0.035147
SEC16B SEC16 homolog B (S. cerevisiae) 0.035147
LIFR leukemia inhibitory factor receptor alpha 0.034927
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2 0.034651
ATP9B ATPase, class II, type 9B 0.034402
RGS12 regulator of G-protein signaling 12 0.033851
TECR trans-2,3-enoyl-CoA reductase 0.033851
ACD adrenocortical dysplasia homolog (mouse) 0.032945
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.03289
ERN1 endoplasmic reticulum to nucleus signaling 1 0.031635
N4BP2L1 NEDD4 binding protein 2-like 1 0.030901
DGKH diacylglycerol kinase, eta 0.029385
IQGAP1 IQ motif containing GTPase activating protein 1 0.02925
KLF3 Kruppel-like factor 3 (basic) 0.027636
SEPP1 selenoprotein P, plasma, 1 0.027261
ARHGEF18 Rho/Rac guanine nucleotide exchange factor (GEF) 18 0.027207
PSMB8 proteasome (prosome, macropain) subunit, beta type, 8 0.025903
CES5A carboxylesterase 5A 0.024576
MPHOSPH9 M-phase phosphoprotein 9 0.02447
TNRC6A trinucleotide repeat containing 6A 0.023313
TBATA thymus, brain and testes associated 0.023076
BIRC2 baculoviral IAP repeat containing 2 0.021635
PPP1R16A protein phosphatase 1, regulatory subunit 16A 0.02101
PARP11 poly (ADP-ribose) polymerase family, member 11 0.020855
CCDC90B coiled-coil domain containing 90B 0.019948
LRP10 low density lipoprotein receptor-related protein 10 0.018348
MIIP migration and invasion inhibitory protein 0.01822
VWA8 von Willebrand factor A domain containing 8 0.017759
CNP 2',3'-cyclic nucleotide 3' phosphodiesterase 0.014279
MZT2A mitotic spindle organizing protein 2A 0.014153
TRO trophinin 0.013852
CENPC centromere protein C 0.013524
GCH1 GTP cyclohydrolase 1 0.013398
ESYT2 extended synaptotagmin-like protein 2 0.010684
ATP6V1C1 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 0.010237
TBL1X transducin (beta)-like 1X-linked 0.008054
TRAF1 TNF receptor-associated factor 1 0.007834
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.007346
SGCE sarcoglycan, epsilon 0.007273
STK4 serine/threonine kinase 4 0.007128
CNOT4 CCR4-NOT transcription complex, subunit 4 0.006741
CBX2 chromobox homolog 2 0.006233
RB1 retinoblastoma 1 0.005653
NBAS neuroblastoma amplified sequence 0.005533
AFG3L1P AFG3-like AAA ATPase 1, pseudogene 0.005509
SPIDR scaffolding protein involved in DNA repair 0.004165
CAPN7 calpain 7 0.003497
CARNS1 carnosine synthase 1 0.002712
TRA2A transformer 2 alpha homolog (Drosophila) 0.002214
ARHGAP12 Rho GTPase activating protein 12 0.001318
OSTM1 osteopetrosis associated transmembrane protein 1 0.001107
FAM168A family with sequence similarity 168, member A 0.001084

decreased expression

Symbol Name Standardized Value
SNX3 sorting nexin 3 -1.27258
SMOC1 SPARC related modular calcium binding 1 -1.26419
KLK3 kallikrein-related peptidase 3 -1.25363
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin -1.24105
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 -1.23775
CD209 CD209 molecule -1.2256
PDXP pyridoxal (pyridoxine, vitamin B6) phosphatase -1.21846
RRP1B ribosomal RNA processing 1B -1.21725
ITGA9 integrin, alpha 9 -1.2117
PHACTR4 phosphatase and actin regulator 4 -1.21138
SRSF10 serine/arginine-rich splicing factor 10 -1.20978
BDKRB2 bradykinin receptor B2 -1.20907
PAPPA pregnancy-associated plasma protein A, pappalysin 1 -1.20519
IL6ST interleukin 6 signal transducer -1.19957
ATP8B4 ATPase, class I, type 8B, member 4 -1.19344
RNASEH2C ribonuclease H2, subunit C -1.18943
FASTKD2 FAST kinase domains 2 -1.18429
LUC7L LUC7-like (S. cerevisiae) -1.16215
ARHGEF40 Rho guanine nucleotide exchange factor (GEF) 40 -1.1609
FOXP2 forkhead box P2 -1.15734
IL17RD interleukin 17 receptor D -1.15649
NDUFAB1 NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa -1.15235
TRMT10A tRNA methyltransferase 10 homolog A (S. cerevisiae) -1.15151
SIKE1 suppressor of IKBKE 1 -1.14734
SRP14 signal recognition particle 14kDa (homologous Alu RNA binding protein) -1.14501
SUZ12 SUZ12 polycomb repressive complex 2 subunit -1.13845
OLFML2B olfactomedin-like 2B -1.13324
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1 -1.13144
ADARB1 adenosine deaminase, RNA-specific, B1 -1.12713
ANO4 anoctamin 4 -1.12421
CASP6 caspase 6, apoptosis-related cysteine peptidase -1.11971
MID1 midline 1 -1.11444
RAB11FIP2 RAB11 family interacting protein 2 (class I) -1.11106
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 -1.10666
HSPA1B heat shock 70kDa protein 1B -1.0846
HSPB1 heat shock 27kDa protein 1 -1.08186
HSPA12A heat shock 70kDa protein 12A -1.07701
METTL3 methyltransferase like 3 -1.07291
MED19 mediator complex subunit 19 -1.06023
BHLHE22 basic helix-loop-helix family, member e22 -1.05578
LUZP1 leucine zipper protein 1 -1.0553
TOP3B topoisomerase (DNA) III beta -1.04914
ADAM11 ADAM metallopeptidase domain 11 -1.04851
APRT adenine phosphoribosyltransferase -1.0406
CAMSAP2 calmodulin regulated spectrin-associated protein family, member 2 -1.03382
MEMO1 mediator of cell motility 1 -1.01074
MCM2 minichromosome maintenance complex component 2 -1.00869
RHOF ras homolog family member F (in filopodia) -1.00652
HNRNPF heterogeneous nuclear ribonucleoprotein F -1.00593
LARP4 La ribonucleoprotein domain family, member 4 -1.00091
TGFBR1 transforming growth factor, beta receptor 1 -0.998351
MEIG1 meiosis/spermiogenesis associated 1 -0.998023
TMEM176B transmembrane protein 176B -0.993402
RGS5 regulator of G-protein signaling 5 -0.987853
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast) -0.979869
HSPA8 heat shock 70kDa protein 8 -0.974983
SORCS1 sortilin-related VPS10 domain containing receptor 1 -0.974857
TMEM238 transmembrane protein 238 -0.97303
RORB RAR-related orphan receptor B -0.968651
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase -0.967013
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) -0.966321
PTGES3L prostaglandin E synthase 3 (cytosolic)-like -0.965631
PJA1 praja ring finger 1, E3 ubiquitin protein ligase -0.944998
MRPL45 mitochondrial ribosomal protein L45 -0.942455
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 -0.939228
RNF182 ring finger protein 182 -0.937593
COMTD1 catechol-O-methyltransferase domain containing 1 -0.929511
VWA5B2 von Willebrand factor A domain containing 5B2 -0.928741
TBP TATA box binding protein -0.924159
SPATA5 spermatogenesis associated 5 -0.923448
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 -0.919029
USP33 ubiquitin specific peptidase 33 -0.913902
CALY calcyon neuron-specific vesicular protein -0.904002
FGF3 fibroblast growth factor 3 -0.903658
TPRKB TP53RK binding protein -0.900352
NEUROD4 neuronal differentiation 4 -0.894097
ZIM2 zinc finger, imprinted 2 -0.89184
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.889876
VAX1 ventral anterior homeobox 1 -0.885806
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 -0.885305
H2AFJ H2A histone family, member J -0.883797
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) -0.879636
SYNCRIP synaptotagmin binding, cytoplasmic RNA interacting protein -0.872843
NSA2 NSA2 ribosome biogenesis homolog (S. cerevisiae) -0.871536
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.869464
PRKCZ protein kinase C, zeta -0.869464
MCM5 minichromosome maintenance complex component 5 -0.866483
TIMM10 translocase of inner mitochondrial membrane 10 homolog (yeast) -0.865619
FAM173B family with sequence similarity 173, member B -0.865619
NEURL1 neuralized E3 ubiquitin protein ligase 1 -0.864919
ZCRB1 zinc finger CCHC-type and RNA binding motif 1 -0.857117
COPS8 COP9 signalosome subunit 8 -0.853246
TFRC transferrin receptor -0.85256
CHORDC1 cysteine and histidine-rich domain (CHORD) containing 1 -0.852191
HSPA9 heat shock 70kDa protein 9 (mortalin) -0.851507
IQCF1 IQ motif containing F1 -0.848154
PRRT3 proline-rich transmembrane protein 3 -0.846071
GIPC3 GIPC PDZ domain containing family, member 3 -0.845394
GTPBP4 GTP binding protein 4 -0.839895
ERMN ermin, ERM-like protein -0.838608
COL24A1 collagen, type XXIV, alpha 1 -0.836148
HTRA1 HtrA serine peptidase 1 -0.833296
HDGF hepatoma-derived growth factor -0.825803
WDR36 WD repeat domain 36 -0.81907
DYNLL2 dynein, light chain, LC8-type 2 -0.81266
SCN8A sodium channel, voltage gated, type VIII alpha subunit -0.810462
FKBP5 FK506 binding protein 5 -0.809101
MBP myelin basic protein -0.809101
MAT2A methionine adenosyltransferase II, alpha -0.806381
MTDH metadherin -0.803965
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.797603
OPRK1 opioid receptor, kappa 1 -0.797365
PCSK2 proprotein convertase subtilisin/kexin type 2 -0.796225
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.795513
MON1B MON1 secretory trafficking family member B -0.791548
MLC1 megalencephalic leukoencephalopathy with subcortical cysts 1 -0.789766
TFDP1 transcription factor Dp-1 -0.786874
OXCT1 3-oxoacid CoA transferase 1 -0.783904
HSF1 heat shock transcription factor 1 -0.778291
LY6G6D lymphocyte antigen 6 complex, locus G6D -0.77788
UBXN4 UBX domain protein 4 -0.774877
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.772883
RNF150 ring finger protein 150 -0.762688
COG8 component of oligomeric golgi complex 8 -0.760745
SDPR serum deprivation response -0.759645
KCNE3 potassium channel, voltage gated subfamily E regulatory beta subunit 3 -0.753665
NDUFAF6 NADH dehydrogenase (ubiquinone) complex I, assembly factor 6 -0.750037
CEP135 centrosomal protein 135kDa -0.749177
NUP107 nucleoporin 107kDa -0.749091
TMEM8B transmembrane protein 8B -0.749006
CLNS1A chloride channel, nucleotide-sensitive, 1A -0.74862
DDX27 DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 -0.739874
PCDH7 protocadherin 7 -0.737861
TWF1 twinfilin actin binding protein 1 -0.73407
TFIP11 tuftelin interacting protein 11 -0.733407
CCRN4L CCR4 carbon catabolite repression 4-like (S. cerevisiae) -0.731217
PAX6 paired box 6 -0.730764
ABI3BP ABI family, member 3 (NESH) binding protein -0.7306
BOLA2 bolA family member 2 -0.720277
PPIL1 peptidylprolyl isomerase (cyclophilin)-like 1 -0.719916
TMIGD1 transmembrane and immunoglobulin domain containing 1 -0.714536
LDB3 LIM domain binding 3 -0.712797
GPR37L1 G protein-coupled receptor 37 like 1 -0.698318
IL4 interleukin 4 -0.693968
NOC4L nucleolar complex associated 4 homolog (S. cerevisiae) -0.69213
GOLIM4 golgi integral membrane protein 4 -0.691644
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit -0.686558
FGF13 fibroblast growth factor 13 -0.68582
NOL8 nucleolar protein 8 -0.685158
MRPS7 mitochondrial ribosomal protein S7 -0.683287
ALDH18A1 aldehyde dehydrogenase 18 family, member A1 -0.681938
CD226 CD226 molecule -0.681356
CCDC86 coiled-coil domain containing 86 -0.677447
NUPL1 nucleoporin like 1 -0.675218
FOXF2 forkhead box F2 -0.674753
ABHD17C abhydrolase domain containing 17C -0.671589
SCAF8 SR-related CTD-associated factor 8 -0.666307
PGK1 phosphoglycerate kinase 1 -0.662696
RNF20 ring finger protein 20, E3 ubiquitin protein ligase -0.658046
ZFP91 ZFP91 zinc finger protein -0.656465
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa -0.655343
IGHMBP2 immunoglobulin mu binding protein 2 -0.649544
GPR68 G protein-coupled receptor 68 -0.644935
PHKG1 phosphorylase kinase, gamma 1 (muscle) -0.644136
VKORC1L1 vitamin K epoxide reductase complex, subunit 1-like 1 -0.643411
INA internexin neuronal intermediate filament protein, alpha -0.631114
CARS cysteinyl-tRNA synthetase -0.631045
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4 -0.629655
AGBL3 ATP/GTP binding protein-like 3 -0.627021
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.625986
SHANK2 SH3 and multiple ankyrin repeat domains 2 -0.625713
SMC1A structural maintenance of chromosomes 1A -0.620542
KAT2A K(lysine) acetyltransferase 2A -0.618989
SOST sclerostin -0.617848
ADGRL3 adhesion G protein-coupled receptor L3 -0.616182
ZNF3 zinc finger protein 3 -0.612209
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.610437
PCDHB14 protocadherin beta 14 -0.607836
RNMT RNA (guanine-7-) methyltransferase -0.607382
CCL3 chemokine (C-C motif) ligand 3 -0.605186
STOM stomatin -0.601863
COMMD5 COMM domain containing 5 -0.599079
GTF2H4 general transcription factor IIH, polypeptide 4, 52kDa -0.588014
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) -0.581893
DHPS deoxyhypusine synthase -0.577064
CENPV centromere protein V -0.576773
CDCA7 cell division cycle associated 7 -0.575554
MMP13 matrix metallopeptidase 13 -0.57118
IKBKAP inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein -0.568683
RCC2 regulator of chromosome condensation 2 -0.5684
SAPCD2 suppressor APC domain containing 2 -0.567218
SSRP1 structure specific recognition protein 1 -0.566319
COIL coilin -0.565199
TMEM41A transmembrane protein 41A -0.564471
FUCA1 fucosidase, alpha-L- 1, tissue -0.564249
APMAP adipocyte plasma membrane associated protein -0.563804
SLC45A2 solute carrier family 45, member 2 -0.563527
HOOK3 hook microtubule-tethering protein 3 -0.562753
FTSJ3 FtsJ homolog 3 (E. coli) -0.561874
AQP6 aquaporin 6, kidney specific -0.559186
TMED5 transmembrane emp24 protein transport domain containing 5 -0.559021
BAG3 BCL2-associated athanogene 3 -0.556258
HBEGF heparin-binding EGF-like growth factor -0.555668
FREM2 FRAS1 related extracellular matrix protein 2 -0.554916
AHSA1 AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) -0.553205
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.552246
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -0.551135
RNF217 ring finger protein 217 -0.544574
ST7L suppression of tumorigenicity 7 like -0.539239
NAA16 N(alpha)-acetyltransferase 16, NatA auxiliary subunit -0.537739
UBE2D3 ubiquitin-conjugating enzyme E2D 3 -0.536941
ACOT7 acyl-CoA thioesterase 7 -0.534366
GCKR glucokinase (hexokinase 4) regulator -0.534071
FNDC1 fibronectin type III domain containing 1 -0.532608
ROMO1 reactive oxygen species modulator 1 -0.529117
PRPF38B pre-mRNA processing factor 38B -0.526784
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.523759
F10 coagulation factor X -0.521577
SNRPD2 small nuclear ribonucleoprotein D2 polypeptide 16.5kDa -0.520973
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 -0.51968
KRT5 keratin 5, type II -0.518262
CCT4 chaperonin containing TCP1, subunit 4 (delta) -0.512202
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) -0.510703
COL3A1 collagen, type III, alpha 1 -0.509648
NRXN1 neurexin 1 -0.508087
SNX5 sorting nexin 5 -0.502966
CSN1S2AP casein alpha s2-like A, pseudogene -0.502378
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -0.501372
DDOST dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit (non-catalytic) -0.501247
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 -0.498188
REXO2 RNA exonuclease 2 -0.498066
RSPH3 radial spoke 3 homolog (Chlamydomonas) -0.497494
NUP133 nucleoporin 133kDa -0.496108
NOL9 nucleolar protein 9 -0.494576
HSPH1 heat shock 105kDa/110kDa protein 1 -0.490724
NOP16 NOP16 nucleolar protein -0.49057
DUSP6 dual specificity phosphatase 6 -0.490452
MAPK10 mitogen-activated protein kinase 10 -0.489753
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.487008
CDK13 cyclin-dependent kinase 13 -0.484997
ARID2 AT rich interactive domain 2 (ARID, RFX-like) -0.484733
FABP5 fatty acid binding protein 5 (psoriasis-associated) -0.483717
IL13 interleukin 13 -0.480198
MMP2 matrix metallopeptidase 2 -0.478774
SERPINB12 serpin peptidase inhibitor, clade B (ovalbumin), member 12 -0.478737
USP24 ubiquitin specific peptidase 24 -0.477941
BRIX1 BRX1, biogenesis of ribosomes -0.477513
GXYLT2 glucoside xylosyltransferase 2 -0.477263
PMM2 phosphomannomutase 2 -0.476977
LDB2 LIM domain binding 2 -0.475411
KLHL21 kelch-like family member 21 -0.474914
ERO1L ERO1-like (S. cerevisiae) -0.473443
NRARP NOTCH-regulated ankyrin repeat protein -0.472369
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1 -0.471228
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.471057
RGS16 regulator of G-protein signaling 16 -0.471023
MRC1 mannose receptor, C type 1 -0.46872
PDZRN4 PDZ domain containing ring finger 4 -0.468014
MYO10 myosin X -0.467746
PRKCI protein kinase C, iota -0.464683
RIF1 replication timing regulatory factor 1 -0.46348
NPY1R neuropeptide Y receptor Y1 -0.461885
AUTS2 autism susceptibility candidate 2 -0.460651
SDF2L1 stromal cell-derived factor 2-like 1 -0.460305
SLC25A29 solute carrier family 25 (mitochondrial carnitine/acylcarnitine carrier), member 29 -0.458689
ZNF316 zinc finger protein 316 -0.456941
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit -0.45588
KCTD4 potassium channel tetramerization domain containing 4 -0.45582
ERRFI1 ERBB receptor feedback inhibitor 1 -0.455373
ISY1 ISY1 splicing factor homolog (S. cerevisiae) -0.455047
HAUS6 HAUS augmin-like complex, subunit 6 -0.45466
ZIC2 Zic family member 2 -0.454541
ADIPOR1 adiponectin receptor 1 -0.454392
SERF1A small EDRK-rich factor 1A (telomeric) -0.452881
MOCS3 molybdenum cofactor synthesis 3 -0.450263
HSPA1A heat shock 70kDa protein 1A -0.449663
AFAP1 actin filament associated protein 1 -0.44713
SLC8A1 solute carrier family 8 (sodium/calcium exchanger), member 1 -0.446441
SBNO1 strawberry notch homolog 1 (Drosophila) -0.445822
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -0.444558
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.444075
IL1A interleukin 1, alpha -0.443699
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14 -0.443151
GPAM glycerol-3-phosphate acyltransferase, mitochondrial -0.442267
ZNF407 zinc finger protein 407 -0.442007
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa -0.441799
IFRD2 interferon-related developmental regulator 2 -0.441203
LRWD1 leucine-rich repeats and WD repeat domain containing 1 -0.440059
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 -0.439256
MIEF1 mitochondrial elongation factor 1 -0.438204
PITX1 paired-like homeodomain 1 -0.432894
XPOT exportin, tRNA -0.432281
CDH2 cadherin 2, type 1, N-cadherin (neuronal) -0.431294
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog -0.431159
MBD2 methyl-CpG binding domain protein 2 -0.430824
EIF4B eukaryotic translation initiation factor 4B -0.429614
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.429592
CACNA1B calcium channel, voltage-dependent, N type, alpha 1B subunit -0.428492
CLIC4 chloride intracellular channel 4 -0.063551
RBM15B RNA binding motif protein 15B -0.061974
SNX13 sorting nexin 13 -0.061235
CLK1 CDC-like kinase 1 -0.060405
LAGE3 L antigen family, member 3 -0.060257
SIDT2 SID1 transmembrane family, member 2 -0.059963
FAM171A2 family with sequence similarity 171, member A2 -0.059945
JAK1 Janus kinase 1 -0.0594
CDK16 cyclin-dependent kinase 16 -0.05925
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 -0.058668
ATP2A3 ATPase, Ca++ transporting, ubiquitous -0.058631
TRIM6-TRIM34 TRIM6-TRIM34 readthrough -0.057749
DIRC2 disrupted in renal carcinoma 2 -0.056891
UNC13C unc-13 homolog C (C. elegans) -0.056777
HELB helicase (DNA) B -0.055226
SH3GLB1 SH3-domain GRB2-like endophilin B1 -0.054858
KIF1C kinesin family member 1C -0.054703
RAPGEF6 Rap guanine nucleotide exchange factor (GEF) 6 -0.054181
DOPEY2 dopey family member 2 -0.053795
ITM2C integral membrane protein 2C -0.052934
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -0.052875
TMCO5B transmembrane and coiled-coil domains 5B, pseudogene -0.052737
RFC3 replication factor C (activator 1) 3, 38kDa -0.051265
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1 -0.050945
CREBRF CREB3 regulatory factor -0.050866
SGK223 homolog of rat pragma of Rnd2 -0.049811
PIK3IP1 phosphoinositide-3-kinase interacting protein 1 -0.049513
KIF14 kinesin family member 14 -0.048227
PCMTD2 protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 -0.048206
MIPEP mitochondrial intermediate peptidase -0.048166
MAN1A2 mannosidase, alpha, class 1A, member 2 -0.048105
PABPN1 poly(A) binding protein, nuclear 1 -0.047198
ZBTB37 zinc finger and BTB domain containing 37 -0.047058
NT5DC1 5'-nucleotidase domain containing 1 -0.046036
IGHM immunoglobulin heavy constant mu -0.045648
TRIM25 tripartite motif containing 25 -0.044462
SCAI suppressor of cancer cell invasion -0.044234
ELF2 E74-like factor 2 (ets domain transcription factor) -0.043986
ENAH enabled homolog (Drosophila) -0.043717
SCD5 stearoyl-CoA desaturase 5 -0.043594
SERTAD2 SERTA domain containing 2 -0.042954
GNG8 guanine nucleotide binding protein (G protein), gamma 8 -0.04114
MTSS1 metastasis suppressor 1 -0.040535
GALNT11 polypeptide N-acetylgalactosaminyltransferase 11 -0.04018
ARL16 ADP-ribosylation factor-like 16 -0.040138
PPP6R3 protein phosphatase 6, regulatory subunit 3 -0.039969
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2 -0.038911
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein -0.037131
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.036746
SPNS1 spinster homolog 1 (Drosophila) -0.036746
TMEM9B TMEM9 domain family, member B -0.036703
PTTG1 pituitary tumor-transforming 1 -0.036084
PRKACB protein kinase, cAMP-dependent, catalytic, beta -0.035466
FAM101B family with sequence similarity 101, member B -0.035295
AKAP13 A kinase (PRKA) anchor protein 13 -0.035273
AQP3 aquaporin 3 (Gill blood group) -0.034712
RAB21 RAB21, member RAS oncogene family -0.034647
PPP1R3E protein phosphatase 1, regulatory subunit 3E -0.034647
AMMECR1L AMMECR1-like -0.034324
SPTBN2 spectrin, beta, non-erythrocytic 2 -0.032727
FAM134C family with sequence similarity 134, member C -0.031704
SCARB2 scavenger receptor class B, member 2 -0.030288
RBM3 RNA binding motif (RNP1, RRM) protein 3 -0.029542
SLC4A11 solute carrier family 4, sodium borate transporter, member 11 -0.02941
FUOM fucose mutarotase -0.02849
CCNI cyclin I -0.028073
RD3 retinal degeneration 3 -0.027984
PARP8 poly (ADP-ribose) polymerase family, member 8 -0.027497
CFLAR CASP8 and FADD-like apoptosis regulator -0.024927
CNOT6 CCR4-NOT transcription complex, subunit 6 -0.023702
BNIP3L BCL2/adenovirus E1B 19kDa interacting protein 3-like -0.023145
TECPR1 tectonin beta-propeller repeat containing 1 -0.023145
COL2A1 collagen, type II, alpha 1 -0.021552
SMCR8 Smith-Magenis syndrome chromosome region, candidate 8 -0.020948
AKAP2 A kinase (PRKA) anchor protein 2 -0.019887
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.019414
CAST calpastatin -0.017831
PNP purine nucleoside phosphorylase -0.0169
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae) -0.016718
CRTC3 CREB regulated transcription coactivator 3 -0.016265
MNT MAX network transcriptional repressor -0.014623
YY1 YY1 transcription factor -0.014487
RET ret proto-oncogene -0.014326
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene -0.014145
DCAF8 DDB1 and CUL4 associated factor 8 -0.013301
MTMR3 myotubularin related protein 3 -0.012038
AHI1 Abelson helper integration site 1 -0.011809
SBNO2 strawberry notch homolog 2 (Drosophila) -0.010385
SRGAP1 SLIT-ROBO Rho GTPase activating protein 1 -0.009509
FOXO1 forkhead box O1 -0.008082
SASH3 SAM and SH3 domain containing 3 -0.007548
PLEC plectin -0.007386
FAM8A1 family with sequence similarity 8, member A1 -0.006923
KLC1 kinesin light chain 1 -0.006785
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 -0.006368
TBX6 T-box 6 -0.005813
ACTL9 actin-like 9 -0.004721
ZBED6 zinc finger, BED-type containing 6 -0.003607
PARP9 poly (ADP-ribose) polymerase family, member 9 -0.001255
LAMB1 laminin, beta 1 -0.001162
MKNK1 MAP kinase interacting serine/threonine kinase 1 -4.87E-4
ALDH6A1 aldehyde dehydrogenase 6 family, member A1 -3.93E-4
TMEM60 transmembrane protein 60 -1.35E-4
Funding