huntington's disease Gene Set

Dataset DISEASES Text-mining Gene-Disease Association Evidence Scores
Category disease or phenotype associations
Type disease
Description A neurodegenerative disease and an autosomal dominant disease that is characterized by unwanted choreatic movements, behavioral and psychiatric disturbances and dementia and has_material_basis_in expansion of CAG triplet repeats (glutamine) resulting in neuron degeneration affecting muscle coordination, cognitive abilities. (Human Disease Ontology, DOID_12858)
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Genes

552 genes co-occuring with the disease huntington's disease in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
HTT huntingtin 4.55658
BDNF brain-derived neurotrophic factor 2.08637
HAP1 huntingtin-associated protein 1 2.06487
JPH3 junctophilin 3 1.9267
ZDHHC17 zinc finger, DHHC-type containing 17 1.74369
ZNF141 zinc finger protein 141 1.7355
ATXN3 ataxin 3 1.73322
HIP1 huntingtin interacting protein 1 1.71134
CALB1 calbindin 1, 28kDa 1.59653
TAC1 tachykinin, precursor 1 1.46891
CHAT choline O-acetyltransferase 1.461
IFT57 intraflagellar transport 57 1.41227
PDE10A phosphodiesterase 10A 1.40395
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1 1.39389
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 1.38603
HSPA4 heat shock 70kDa protein 4 1.38297
RBFOX3 RNA binding protein, fox-1 homolog (C. elegans) 3 1.3821
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.3821
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) 1.37381
NPY neuropeptide Y 1.37163
PENK proenkephalin 1.37076
CNTF ciliary neurotrophic factor 1.36597
PPP1R1B protein phosphatase 1, regulatory (inhibitor) subunit 1B 1.36553
HDAC9 histone deacetylase 9 1.34766
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 1.33327
CPLX2 complexin 2 1.29134
REST RE1-silencing transcription factor 1.28392
PVALB parvalbumin 1.28304
DRD2 dopamine receptor D2 1.2813
HSF1 heat shock transcription factor 1 1.27955
CNR1 cannabinoid receptor 1 (brain) 1.26386
CREBBP CREB binding protein 1.2521
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.24906
ADORA2A adenosine A2a receptor 1.2395
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 1.2369
DCTN1 dynactin 1 1.23429
CREB1 cAMP responsive element binding protein 1 1.22518
SST somatostatin 1.19575
ATN1 atrophin 1 1.19489
TGM2 transglutaminase 2 1.19273
TBP TATA box binding protein 1.18626
AR androgen receptor 1.17378
ATXN1 ataxin 1 1.16863
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 1.16435
ACHE acetylcholinesterase (Yt blood group) 1.15837
F8A2 coagulation factor VIII-associated 2 1.15325
F8A1 coagulation factor VIII-associated 1 1.15325
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 1.13501
AADAT aminoadipate aminotransferase 1.11982
ZDHHC13 zinc finger, DHHC-type containing 13 1.1194
SOD2 superoxide dismutase 2, mitochondrial 1.11687
TH tyrosine hydroxylase 1.11141
ATXN7 ataxin 7 1.1051
GRM1 glutamate receptor, metabotropic 1 1.103
SYNDIG1L synapse differentiation inducing 1-like 1.10258
SIRT2 sirtuin 2 1.10132
DNM1L dynamin 1-like 1.09293
SH3GL3 SH3-domain GRB2-like 3 1.08118
HDAC3 histone deacetylase 3 1.0606
SIRT1 sirtuin 1 1.05976
FAM193A family with sequence similarity 193, member A 1.05807
DNAH14 dynein, axonemal, heavy chain 14 1.05471
DNAH12 dynein, axonemal, heavy chain 12 1.05471
NPS neuropeptide S 1.04504
NGF nerve growth factor (beta polypeptide) 1.03409
RASD2 RASD family, member 2 1.03367
TCERG1 transcription elongation regulator 1 1.03367
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 1.02608
GDNF glial cell derived neurotrophic factor 1.02313
HIP1R huntingtin interacting protein 1 related 1.0071
PABPC4 poly(A) binding protein, cytoplasmic 4 (inducible form) 1.00583
GSX2 GS homeobox 2 0.991909
PDYN prodynorphin 0.991065
CALB2 calbindin 2 0.990644
AFF2 AF4/FMR2 family, member 2 0.976323
QPRT quinolinate phosphoribosyltransferase 0.951604
ARFIP2 ADP-ribosylation factor interacting protein 2 0.947852
TNFRSF21 tumor necrosis factor receptor superfamily, member 21 0.935385
HCRT hypocretin (orexin) neuropeptide precursor 0.93
GAPDH glyceraldehyde-3-phosphate dehydrogenase 0.913492
ZNF395 zinc finger protein 395 0.89582
PPARGC1A peroxisome proliferator-activated receptor gamma, coactivator 1 alpha 0.89541
DNAH9 dynein, axonemal, heavy chain 9 0.889668
GRM5 glutamate receptor, metabotropic 5 0.887618
LIN7B lin-7 homolog B (C. elegans) 0.881062
TGM1 transglutaminase 1 0.872053
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.867959
UBQLN1 ubiquilin 1 0.849536
FEN1 flap structure-specific endonuclease 1 0.843392
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 0.838885
SLC17A7 solute carrier family 17 (vesicular glutamate transporter), member 7 0.838476
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.836017
MTOR mechanistic target of rapamycin (serine/threonine kinase) 0.834788
PPARG peroxisome proliferator-activated receptor gamma 0.833968
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 0.831508
METRN meteorin, glial cell differentiation regulator 0.824948
DNAH5 dynein, axonemal, heavy chain 5 0.821667
GFAP glial fibrillary acidic protein 0.820847
DCX doublecortin 0.815924
CCBL1 cysteine conjugate-beta lyase, cytoplasmic 0.815924
UBE2K ubiquitin-conjugating enzyme E2K 0.812642
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6 0.805257
NRTN neurturin 0.802795
SIRT3 sirtuin 3 0.798282
PFDN2 prefoldin subunit 2 0.795411
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.792131
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.791311
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.785165
MSH3 mutS homolog 3 0.779023
CSPG5 chondroitin sulfate proteoglycan 5 (neuroglycan C) 0.776568
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.770027
GYPE glycophorin E (MNS blood group) 0.767985
HAAO 3-hydroxyanthranilate 3,4-dioxygenase 0.765943
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.765535
BECN1 beclin 1, autophagy related 0.76431
CDK5 cyclin-dependent kinase 5 0.756564
KALRN kalirin, RhoGEF kinase 0.74761
NTF4 neurotrophin 4 0.745578
PRPF40B PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae) 0.741517
TOLLIP toll interacting protein 0.716828
PFDN5 prefoldin subunit 5 0.714811
ABAT 4-aminobutyrate aminotransferase 0.714811
SIRT6 sirtuin 6 0.709572
NFE2L2 nuclear factor, erythroid 2-like 2 0.708767
BAX BCL2-associated X protein 0.706754
SYNPR synaptoporin 0.703134
CHCHD2 coiled-coil-helix-coiled-coil-helix domain containing 2 0.703134
FUS FUS RNA binding protein 0.699919
RHCE Rh blood group, CcEe antigens 0.699517
UBE2H ubiquitin-conjugating enzyme E2H 0.697911
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.697911
ATXN2 ataxin 2 0.69751
DTX1 deltex 1, E3 ubiquitin ligase 0.693098
ADD1 adducin 1 (alpha) 0.691896
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.691896
DENR density-regulated protein 0.689492
SIRT5 sirtuin 5 0.688692
SIRT4 sirtuin 4 0.687891
RPH3A rabphilin 3A 0.685891
GLUL glutamate-ammonia ligase 0.684292
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.681495
SIRT7 sirtuin 7 0.678701
MFN1 mitofusin 1 0.673917
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) 0.66914
SYT10 synaptotagmin X 0.66914
FAAH fatty acid amide hydrolase 0.662387
NTS neurotensin 0.656441
ZRANB1 zinc finger, RAN-binding domain containing 1 0.654067
VCP valosin containing protein 0.65288
CAT catalase 0.652484
NTF3 neurotrophin 3 0.650508
GOLGA3 golgin A3 0.648533
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.645375
SFMBT2 Scm-like with four mbt domains 2 0.639857
STRIP1 striatin interacting protein 1 0.639857
ZNF484 zinc finger protein 484 0.639857
STRIP2 striatin interacting protein 2 0.639857
NGFR nerve growth factor receptor 0.638676
DICER1 dicer 1, ribonuclease type III 0.638676
H3F3A H3 histone, family 3A 0.638282
H3F3B H3 histone, family 3B (H3.3B) 0.638282
SCAMP5 secretory carrier membrane protein 5 0.635135
ZDHHC12 zinc finger, DHHC-type containing 12 0.635135
GOLGA8G golgin A8 family, member G 0.630027
GOLGA8EP golgin A8 family, member E, pseudogene 0.630027
GOLGA8F golgin A8 family, member F 0.630027
PRNP prion protein 0.628457
ATG5 autophagy related 5 0.614356
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) 0.610448
CCK cholecystokinin 0.606152
FXN frataxin 0.604981
FTL ferritin, light polypeptide 0.604591
SLA2 Src-like-adaptor 2 0.60264
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.60147
SGTB small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta 0.596012
GPR155 G protein-coupled receptor 155 0.592506
SP1 Sp1 transcription factor 0.592506
PSMD12 proteasome (prosome, macropain) 26S subunit, non-ATPase, 12 0.591727
ACO2 aconitase 2, mitochondrial 0.590169
SETD2 SET domain containing 2 0.58939
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.589001
NCOR1 nuclear receptor corepressor 1 0.589001
IGF1 insulin-like growth factor 1 (somatomedin C) 0.588222
TP53 tumor protein p53 0.586276
DRD5 dopamine receptor D5 0.586276
MAP3K10 mitogen-activated protein kinase kinase kinase 10 0.581217
FOS FBJ murine osteosarcoma viral oncogene homolog 0.579661
SCN4B sodium channel, voltage gated, type IV beta subunit 0.578494
MFN2 mitofusin 2 0.577327
MBNL1 muscleblind-like splicing regulator 1 0.576161
C10ORF2 chromosome 10 open reading frame 2 0.572273
TMEM185A transmembrane protein 185A 0.571107
RHD Rh blood group, D antigen 0.569163
PDE1B phosphodiesterase 1B, calmodulin-dependent 0.568386
MAPT microtubule-associated protein tau 0.559062
HDAC6 histone deacetylase 6 0.557897
GPRASP2 G protein-coupled receptor associated sorting protein 2 0.552463
CHRDL2 chordin-like 2 0.551298
DNAJC5 DnaJ (Hsp40) homolog, subfamily C, member 5 0.549359
TFAM transcription factor A, mitochondrial 0.548583
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.548583
OGG1 8-oxoguanine DNA glycosylase 0.546644
MLF1 myeloid leukemia factor 1 0.545868
DLG4 discs, large homolog 4 (Drosophila) 0.541217
CARD17 caspase recruitment domain family, member 17 0.540055
HTN1 histatin 1 0.535796
GSG1L GSG1-like 0.535409
ERN1 endoplasmic reticulum to nucleus signaling 1 0.533475
PPP1R9A protein phosphatase 1, regulatory subunit 9A 0.533475
SPRED3 sprouty-related, EVH1 domain containing 3 0.531541
KCNA6 potassium channel, voltage gated shaker related subfamily A, member 6 0.530768
PQBP1 polyglutamine binding protein 1 0.530381
INS insulin 0.528063
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.528063
MSH2 mutS homolog 2 0.525746
HSPA8 heat shock 70kDa protein 8 0.52536
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8 0.524588
GRINA glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) 0.519575
NOG noggin 0.518805
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.518034
C9ORF72 chromosome 9 open reading frame 72 0.517265
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 0.516879
TLK2 tousled-like kinase 2 0.516879
SUPT4H1 suppressor of Ty 4 homolog 1 (S. cerevisiae) 0.516494
BCHE butyrylcholinesterase 0.51611
GRM2 glutamate receptor, metabotropic 2 0.51534
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.513033
DRD1 dopamine receptor D1 0.509192
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.505356
HDAC4 histone deacetylase 4 0.50459
LATS1 large tumor suppressor kinase 1 0.503824
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) 0.503441
GRIK2 glutamate receptor, ionotropic, kainate 2 0.501527
JUN jun proto-oncogene 0.498467
TRIM4 tripartite motif containing 4 0.498085
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa 0.498085
ZDHHC15 zinc finger, DHHC-type containing 15 0.497321
MAPK8 mitogen-activated protein kinase 8 0.495411
EMX1 empty spiracles homeobox 1 0.494648
ABHD6 abhydrolase domain containing 6 0.491215
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.487788
NOP14 NOP14 nucleolar protein 0.487027
GRK4 G protein-coupled receptor kinase 4 0.485885
TOMM20 translocase of outer mitochondrial membrane 20 homolog (yeast) 0.480945
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1 0.480186
QDPR quinoid dihydropteridine reductase 0.477909
CLSPN claspin 0.47374
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1) 0.472604
SPTBN2 spectrin, beta, non-erythrocytic 2 0.469576
CHRM4 cholinergic receptor, muscarinic 4 0.467684
IGHV3-30 immunoglobulin heavy variable 3-30 0.465416
GSTA3 glutathione S-transferase alpha 3 0.465038
TCF20 transcription factor 20 (AR1) 0.463527
GSTA2 glutathione S-transferase alpha 2 0.463527
GSTA4 glutathione S-transferase alpha 4 0.462394
MAOB monoamine oxidase B 0.462016
HDAC2 histone deacetylase 2 0.458996
OPTN optineurin 0.458996
DCTN3 dynactin 3 (p22) 0.458619
CSPP1 centrosome and spindle pole associated protein 1 0.458241
XK X-linked Kx blood group 0.457487
GSTA1 glutathione S-transferase alpha 1 0.456732
GAMT guanidinoacetate N-methyltransferase 0.456355
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 0.455978
CPB1 carboxypeptidase B1 (tissue) 0.455978
NSG1 neuron specific gene family member 1 0.455601
ACBD3 acyl-CoA binding domain containing 3 0.453339
AKAP8L A kinase (PRKA) anchor protein 8-like 0.449194
CPLX1 complexin 1 0.448817
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.447311
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 0.445052
HDAC5 histone deacetylase 5 0.4443
IDUA iduronidase, alpha-L- 0.443547
CACNB1 calcium channel, voltage-dependent, beta 1 subunit 0.442795
CRYAB crystallin, alpha B 0.44129
NOTUM notum pectinacetylesterase homolog (Drosophila) 0.439034
SYP synaptophysin 0.435651
RAB3A RAB3A, member RAS oncogene family 0.434899
PDE4A phosphodiesterase 4A, cAMP-specific 0.434899
NRF1 nuclear respiratory factor 1 0.434899
FTH1 ferritin, heavy polypeptide 1 0.432646
PPIF peptidylprolyl isomerase F 0.431894
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.430393
ACY3 aminoacylase 3 0.427765
NKX2-1 NK2 homeobox 1 0.427015
UBC ubiquitin C 0.426265
TUG1 taurine up-regulated 1 (non-protein coding) 0.424389
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.42364
APOE apolipoprotein E 0.42214
MAP3K13 mitogen-activated protein kinase kinase kinase 13 0.42139
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.416521
PIK3C3 phosphatidylinositol 3-kinase, catalytic subunit type 3 0.41465
GRAP2 GRB2-related adaptor protein 2 0.410535
GJC2 gap junction protein, gamma 2, 47kDa 0.409414
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1 0.408666
GPX5 glutathione peroxidase 5 0.407919
HDAC1 histone deacetylase 1 0.407919
GPX4 glutathione peroxidase 4 0.404931
H2AFY H2A histone family, member Y 0.404557
NUMA1 nuclear mitotic apparatus protein 1 0.401199
KEL Kell blood group, metallo-endopeptidase 0.400826
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 0.400453
RCOR1 REST corepressor 1 0.396725
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.396725
SYN1 synapsin I 0.393746
PFN1 profilin 1 0.393374
CCBL2 cysteine conjugate-beta lyase 2 0.392257
NEUROD6 neuronal differentiation 6 0.390397
MAB21L1 mab-21-like 1 (C. elegans) 0.390025
GPX1 glutathione peroxidase 1 0.389653
BRCA1 breast cancer 1, early onset 0.387051
REM1 RAS (RAD and GEM)-like GTP-binding 1 0.386308
SYN2 synapsin II 0.382966
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.382223
HMOX1 heme oxygenase 1 0.379997
TFEB transcription factor EB 0.379626
CS citrate synthase 0.378143
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 0.37555
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1 0.375179
PKIB protein kinase (cAMP-dependent, catalytic) inhibitor beta 0.372958
GCH1 GTP cyclohydrolase 1 0.371477
AGPAT1 1-acylglycerol-3-phosphate O-acyltransferase 1 0.365932
UBB ubiquitin B 0.362978
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.362239
SLC2A4RG SLC2A4 regulator 0.361133
PARK2 parkin RBR E3 ubiquitin protein ligase 0.360026
TDO2 tryptophan 2,3-dioxygenase 0.35892
CDK5R2 cyclin-dependent kinase 5, regulatory subunit 2 (p39) 0.357814
MLF2 myeloid leukemia factor 2 0.356341
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.355604
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 0.354868
PANK2 pantothenate kinase 2 0.354131
UBA1 ubiquitin-like modifier activating enzyme 1 0.349349
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) 0.347879
NES nestin 0.347511
ANKRD23 ankyrin repeat domain 23 0.344574
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 0.344207
POP4 processing of precursor 4, ribonuclease P/MRP subunit (S. cerevisiae) 0.344207
TBX6 T-box 6 0.343473
LHX9 LIM homeobox 9 0.341639
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1 0.339806
MAP3K12 mitogen-activated protein kinase kinase kinase 12 0.339073
PFN4 profilin family, member 4 0.338341
PCDH20 protocadherin 20 0.337975
ZDHHC14 zinc finger, DHHC-type containing 14 0.33651
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.33651
ATG14 autophagy related 14 0.334681
NEFH neurofilament, heavy polypeptide 0.333218
HDAC7 histone deacetylase 7 0.329565
HSPB8 heat shock 22kDa protein 8 0.328469
ACOX3 acyl-CoA oxidase 3, pristanoyl 0.325187
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit 0.324823
CHRM1 cholinergic receptor, muscarinic 1 0.324458
DNAH8 dynein, axonemal, heavy chain 8 0.324094
COQ7 coenzyme Q7 homolog, ubiquinone (yeast) 0.323002
CRH corticotropin releasing hormone 0.321181
USP28 ubiquitin specific peptidase 28 0.320817
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.316456
SLC5A5 solute carrier family 5 (sodium/iodide cotransporter), member 5 0.315729
FOLH1B folate hydrolase 1B 0.314278
ZDHHC9 zinc finger, DHHC-type containing 9 0.312102
MAOA monoamine oxidase A 0.309928
CTSD cathepsin D 0.308842
FRMD6 FERM domain containing 6 0.307395
POU3F3 POU class 3 homeobox 3 0.307395
NEFM neurofilament, medium polypeptide 0.30631
CORT cortistatin 0.30342
TNN tenascin N 0.302698
UBQLN2 ubiquilin 2 0.301976
CYP2D7 cytochrome P450, family 2, subfamily D, polypeptide 7 (gene/pseudogene) 0.301615
SAE1 SUMO1 activating enzyme subunit 1 0.301254
PCP4 Purkinje cell protein 4 0.301254
COX4I2 cytochrome c oxidase subunit IV isoform 2 (lung) 0.299452
UHRF2 ubiquitin-like with PHD and ring finger domains 2, E3 ubiquitin protein ligase 0.297651
GREM2 gremlin 2, DAN family BMP antagonist 0.296571
NMNAT3 nicotinamide nucleotide adenylyltransferase 3 0.296211
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta 0.295851
GPM6A glycoprotein M6A 0.295492
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.295492
TNRC6A trinucleotide repeat containing 6A 0.292257
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6 0.291898
UBE3A ubiquitin protein ligase E3A 0.290462
NSF N-ethylmaleimide-sensitive factor 0.290103
CAPN7 calpain 7 0.289027
FOXP2 forkhead box P2 0.28831
TUBA1A tubulin, alpha 1a 0.287952
HDAC11 histone deacetylase 11 0.287593
AGO2 argonaute RISC catalytic component 2 0.285444
SHD Src homology 2 domain containing transforming protein D 0.285086
SNORA29 small nucleolar RNA, H/ACA box 29 0.284371
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 0.283655
AATF apoptosis antagonizing transcription factor 0.283297
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.283297
SLC18A3 solute carrier family 18 (vesicular acetylcholine transporter), member 3 0.282582
CAPRIN1 cell cycle associated protein 1 0.280796
POU3F2 POU class 3 homeobox 2 0.279724
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.27794
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 0.277227
RGS2 regulator of G-protein signaling 2 0.27687
PFN2 profilin 2 0.274732
ADCY2 adenylate cyclase 2 (brain) 0.273664
VGF VGF nerve growth factor inducible 0.272241
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 0.27153
PTMS parathymosin 0.27153
GNA15 guanine nucleotide binding protein (G protein), alpha 15 (Gq class) 0.270108
MGLL monoglyceride lipase 0.268687
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 0.267267
RPS27A ribosomal protein S27a 0.266558
MXD1 MAX dimerization protein 1 0.266203
TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast) 0.265494
KEAP1 kelch-like ECH-associated protein 1 0.26514
DBI diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) 0.264431
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 0.264431
MTDH metadherin 0.264431
SUMO3 small ubiquitin-like modifier 3 0.264077
GLS glutaminase 0.262306
CUX2 cut-like homeobox 2 0.261952
UBA2 ubiquitin-like modifier activating enzyme 2 0.260538
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 0.260538
DAD1 defender against cell death 1 0.258417
FOXP1 forkhead box P1 0.257711
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.257358
AK7 adenylate kinase 7 0.257358
GRK6 G protein-coupled receptor kinase 6 0.255946
PANK1 pantothenate kinase 1 0.255946
FMNL3 formin-like 3 0.255241
HOMER2 homer scaffolding protein 2 0.255241
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.254536
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 0.253479
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.253127
ZDHHC8 zinc finger, DHHC-type containing 8 0.252422
PSEN1 presenilin 1 0.251015
PTPRD protein tyrosine phosphatase, receptor type, D 0.248554
SYT4 synaptotagmin IV 0.248554
SUMO2 small ubiquitin-like modifier 2 0.248203
CP ceruloplasmin (ferroxidase) 0.247501
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator 0.246098
ATG4B autophagy related 4B, cysteine peptidase 0.245396
DUSP1 dual specificity phosphatase 1 0.245396
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.242945
ROCK1P1 Rho-associated, coiled-coil containing protein kinase 1 pseudogene 1 0.242245
CARTPT CART prepropeptide 0.242245
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa 0.241546
FNTA farnesyltransferase, CAAX box, alpha 0.241546
HPCA hippocalcin 0.241546
NAPEPLD N-acyl phosphatidylethanolamine phospholipase D 0.240847
TTBK1 tau tubulin kinase 1 0.240148
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 0.240148
BAG1 BCL2-associated athanogene 0.23945
BTF3 basic transcription factor 3 0.238752
HTRA2 HtrA serine peptidase 2 0.23666
SHH sonic hedgehog 0.23666
CLIP1 CAP-GLY domain containing linker protein 1 0.235964
IDO1 indoleamine 2,3-dioxygenase 1 0.23492
SERAC1 serine active site containing 1 0.23492
UBE2E3 ubiquitin-conjugating enzyme E2E 3 0.234225
SAP30 Sin3A-associated protein, 30kDa 0.233183
DLD dihydrolipoamide dehydrogenase 0.232489
CBS cystathionine-beta-synthase 0.231795
MAP2 microtubule-associated protein 2 0.231102
HACE1 HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 0.230409
EN2 engrailed homeobox 2 0.230063
CDH8 cadherin 8, type 2 0.229024
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.227988
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.226262
CSNK1D casein kinase 1, delta 0.226262
XPO1 exportin 1 0.223853
ATG7 autophagy related 7 0.223509
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) 0.219057
CAST calpastatin 0.215992
PRL prolactin 0.215992
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.215992
SIAH1 siah E3 ubiquitin protein ligase 1 0.215653
VNN2 vanin 2 0.214297
UBE2S ubiquitin-conjugating enzyme E2S 0.213959
TOM1 target of myb1 (chicken) 0.213959
SREBF2 sterol regulatory element binding transcription factor 2 0.211597
NUB1 negative regulator of ubiquitin-like proteins 1 0.211261
SPAG11A sperm associated antigen 11A 0.210925
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 0.210253
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.209918
ROCK1 Rho-associated, coiled-coil containing protein kinase 1 0.209918
TRH thyrotropin-releasing hormone 0.207912
VRK2 vaccinia related kinase 2 0.207578
DCTN2 dynactin 2 (p50) 0.207245
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.206913
NR2E1 nuclear receptor subfamily 2, group E, member 1 0.20658
GRID2 glutamate receptor, ionotropic, delta 2 0.204263
PCLO piccolo presynaptic cytomatrix protein 0.203275
BCKDK branched chain ketoacid dehydrogenase kinase 0.202946
ACTN2 actinin, alpha 2 0.20229
LIMD1 LIM domains containing 1 0.199681
RYBP RING1 and YY1 binding protein 0.199356
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.199033
SOX2 SRY (sex determining region Y)-box 2 0.198709
AK1 adenylate kinase 1 0.19742
NOS1 nitric oxide synthase 1 (neuronal) 0.197099
SARNP SAP domain containing ribonucleoprotein 0.197099
KCNJ4 potassium channel, inwardly rectifying subfamily J, member 4 0.196459
TSPO translocator protein (18kDa) 0.196139
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) 0.194865
DGKE diacylglycerol kinase, epsilon 64kDa 0.194865
TOMM40 translocase of outer mitochondrial membrane 40 homolog (yeast) 0.194232
TTL tubulin tyrosine ligase 0.194232
PABPN1 poly(A) binding protein, nuclear 1 0.192971
MAST4 microtubule associated serine/threonine kinase family member 4 0.192657
PTPRA protein tyrosine phosphatase, receptor type, A 0.192344
LSAMP limbic system-associated membrane protein 0.190168
GMFB glia maturation factor, beta 0.189551
VPS4A vacuolar protein sorting 4 homolog A (S. cerevisiae) 0.187719
H2AFX H2A histone family, member X 0.187415
AIF1 allograft inflammatory factor 1 0.18651
MSH6 mutS homolog 6 0.185313
GRIA4 glutamate receptor, ionotropic, AMPA 4 0.185016
CHMP2B charged multivesicular body protein 2B 0.183835
SGK1 serum/glucocorticoid regulated kinase 1 0.183541
DIABLO diablo, IAP-binding mitochondrial protein 0.182375
MIR10B microRNA 10b 0.182086
SPAG11B sperm associated antigen 11B 0.18151
ELP3 elongator acetyltransferase complex subunit 3 0.18151
NPY2R neuropeptide Y receptor Y2 0.178682
ITPR3 inositol 1,4,5-trisphosphate receptor, type 3 0.178126
BAG3 BCL2-associated athanogene 3 0.177301
PTPRT protein tyrosine phosphatase, receptor type, T 0.177301
NBR1 neighbor of BRCA1 gene 1 0.174354
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.174093
MAP2K6 mitogen-activated protein kinase kinase 6 0.173832
VDAC1 voltage-dependent anion channel 1 0.172038
GSK3B glycogen synthase kinase 3 beta 0.171785
UFD1L ubiquitin fusion degradation 1 like (yeast) 0.171785
RAD23A RAD23 homolog A (S. cerevisiae) 0.171286
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.170299
GSR glutathione reductase 0.169091
TNNI2 troponin I type 2 (skeletal, fast) 0.169091
TFRC transferrin receptor 0.168854
CARD16 caspase recruitment domain family, member 16 0.168854
SETDB1 SET domain, bifurcated 1 0.164359
NPEPPS aminopeptidase puromycin sensitive 0.164359
TP53INP1 tumor protein p53 inducible nuclear protein 1 0.164149
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.163523
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.162306
PCNA proliferating cell nuclear antigen 0.161912
RAB8A RAB8A, member RAS oncogene family 0.160761
PLXND1 plexin D1 0.160761
MAPK14 mitogen-activated protein kinase 14 0.160574
UCP1 uncoupling protein 1 (mitochondrial, proton carrier) 0.160387
FGFR3 fibroblast growth factor receptor 3 0.160387
BAIAP2 BAI1-associated protein 2 0.159838
VIPR1 vasoactive intestinal peptide receptor 1 0.159838
KIAA0196 KIAA0196 0.159302
DNTT DNA nucleotidylexotransferase 0.159124
RNF4 ring finger protein 4 0.158097