| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hycanthone-3229 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AHNAK2 | AHNAK nucleoprotein 2 |
| AK1 | adenylate kinase 1 |
| ALDH2 | aldehyde dehydrogenase 2 family (mitochondrial) |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ARL2BP | ADP-ribosylation factor-like 2 binding protein |
| BAX | BCL2-associated X protein |
| BDKRB2 | bradykinin receptor B2 |
| BTG2 | BTG family, member 2 |
| C1QTNF9B-AS1 | C1QTNF9B antisense RNA 1 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCDC71 | coiled-coil domain containing 71 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 |
| CFLAR | CASP8 and FADD-like apoptosis regulator |
| COL14A1 | collagen, type XIV, alpha 1 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 |
| DPP4 | dipeptidyl-peptidase 4 |
| DRD2 | dopamine receptor D2 |
| EFNB3 | ephrin-B3 |
| EPHA2 | EPH receptor A2 |
| EVA1B | eva-1 homolog B (C. elegans) |
| FAS | Fas cell surface death receptor |
| FCMR | Fc fragment of IgM receptor |
| FDXR | ferredoxin reductase |
| FGB | fibrinogen beta chain |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FOSL1 | FOS-like antigen 1 |
| FYB | FYN binding protein |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GPR143 | G protein-coupled receptor 143 |
| GPR87 | G protein-coupled receptor 87 |
| HAAO | 3-hydroxyanthranilate 3,4-dioxygenase |
| HLA-DQB1 | major histocompatibility complex, class II, DQ beta 1 |
| HOXA4 | homeobox A4 |
| HPSE2 | heparanase 2 (inactive) |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| JAG1 | jagged 1 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 |
| KLF13 | Kruppel-like factor 13 |
| LAMC3 | laminin, gamma 3 |
| LIF | leukemia inhibitory factor |
| LIMK2 | LIM domain kinase 2 |
| LOC157562 | uncharacterized LOC157562 |
| LY6D | lymphocyte antigen 6 complex, locus D |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MIR22HG | MIR22 host gene |
| MR1 | major histocompatibility complex, class I-related |
| NHLH2 | nescient helix loop helix 2 |
| NOTCH1 | notch 1 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| PHLDA3 | pleckstrin homology-like domain, family A, member 3 |
| PI4K2A | phosphatidylinositol 4-kinase type 2 alpha |
| PIDD1 | p53-induced death domain protein 1 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) |
| PITX1 | paired-like homeodomain 1 |
| PLAU | plasminogen activator, urokinase |
| PLK3 | polo-like kinase 3 |
| PNPLA3 | patatin-like phospholipase domain containing 3 |
| PSCA | prostate stem cell antigen |
| PSMD9 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 |
| PVT1 | Pvt1 oncogene (non-protein coding) |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats |
| RRBP1 | ribosome binding protein 1 |
| S100A2 | S100 calcium binding protein A2 |
| SDHB | succinate dehydrogenase complex, subunit B, iron sulfur (Ip) |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SESN1 | sestrin 1 |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SH3BP2 | SH3-domain binding protein 2 |
| SLC7A8 | solute carrier family 7 (amino acid transporter light chain, L system), member 8 |
| SMAD4 | SMAD family member 4 |
| SPARCL1 | SPARC-like 1 (hevin) |
| SVEP1 | sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 |
| TBCD | tubulin folding cofactor D |
| TCP11L1 | t-complex 11, testis-specific-like 1 |
| TIGAR | TP53 induced glycolysis regulatory phosphatase |
| TMEM176A | transmembrane protein 176A |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFRSF10C | tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TP53I3 | tumor protein p53 inducible protein 3 |
| TRIB2 | tribbles pseudokinase 2 |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USP53 | ubiquitin specific peptidase 53 |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WSCD1 | WSC domain containing 1 |
| XPC | xeroderma pigmentosum, complementation group C |
| ZMAT3 | zinc finger, matrin-type 3 |
| ZNF747 | zinc finger protein 747 |
| ZNF750 | zinc finger protein 750 |
| Symbol | Name |
|---|---|
| ABHD17B | abhydrolase domain containing 17B |
| ALDH1B1 | aldehyde dehydrogenase 1 family, member B1 |
| AMD1 | adenosylmethionine decarboxylase 1 |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BMP4 | bone morphogenetic protein 4 |
| BORA | bora, aurora kinase A activator |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 |
| C11ORF63 | chromosome 11 open reading frame 63 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CA5BP1 | carbonic anhydrase VB pseudogene 1 |
| CARD8 | caspase recruitment domain family, member 8 |
| CD302 | CD302 molecule |
| CDT1 | chromatin licensing and DNA replication factor 1 |
| CEMIP | cell migration inducing protein, hyaluronan binding |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CLCN5 | chloride channel, voltage-sensitive 5 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COA7 | cytochrome c oxidase assembly factor 7 (putative) |
| CTH | cystathionine gamma-lyase |
| DAGLA | diacylglycerol lipase, alpha |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DNA2 | DNA replication helicase/nuclease 2 |
| DSCAM | Down syndrome cell adhesion molecule |
| E2F8 | E2F transcription factor 8 |
| EMID1 | EMI domain containing 1 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXO1 | exonuclease 1 |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FBXL6 | F-box and leucine-rich repeat protein 6 |
| FBXO5 | F-box protein 5 |
| FJX1 | four jointed box 1 (Drosophila) |
| GJA1 | gap junction protein, alpha 1, 43kDa |
| GPC3 | glypican 3 |
| GPR19 | G protein-coupled receptor 19 |
| HIST1H1B | histone cluster 1, H1b |
| HIST1H2AI | histone cluster 1, H2ai |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| HJURP | Holliday junction recognition protein |
| HPSE | heparanase |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL15RA | interleukin 15 receptor, alpha |
| ITPKB | inositol-trisphosphate 3-kinase B |
| KIF14 | kinesin family member 14 |
| LINC00115 | long intergenic non-protein coding RNA 115 |
| LYZ | lysozyme |
| LZTS3 | leucine zipper, putative tumor suppressor family member 3 |
| MBNL3 | muscleblind-like splicing regulator 3 |
| MRPS18C | mitochondrial ribosomal protein S18C |
| MTA2 | metastasis associated 1 family, member 2 |
| MUC3A | mucin 3A, cell surface associated |
| MVD | mevalonate (diphospho) decarboxylase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NDC80 | NDC80 kinetochore complex component |
| NLK | nemo-like kinase |
| NPFFR1 | neuropeptide FF receptor 1 |
| NUDT18 | nudix (nucleoside diphosphate linked moiety X)-type motif 18 |
| OR7E156P | olfactory receptor, family 7, subfamily E, member 156 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PEX10 | peroxisomal biogenesis factor 10 |
| PLA2G3 | phospholipase A2, group III |
| PODXL2 | podocalyxin-like 2 |
| REM1 | RAS (RAD and GEM)-like GTP-binding 1 |
| RHPN1-AS1 | RHPN1 antisense RNA 1 (head to head) |
| RIN2 | Ras and Rab interactor 2 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| ROM1 | retinal outer segment membrane protein 1 |
| SCGB2A2 | secretoglobin, family 2A, member 2 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SKA1 | spindle and kinetochore associated complex subunit 1 |
| SKIV2L | superkiller viralicidic activity 2-like (S. cerevisiae) |
| SLC16A10 | solute carrier family 16 (aromatic amino acid transporter), member 10 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC35C1 | solute carrier family 35 (GDP-fucose transporter), member C1 |
| SLC44A1 | solute carrier family 44 (choline transporter), member 1 |
| SLC9A2 | solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SNHG20 | small nucleolar RNA host gene 20 |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SREK1IP1 | SREK1-interacting protein 1 |
| SSBP3 | single stranded DNA binding protein 3 |
| TDRD1 | tudor domain containing 1 |
| TMC5 | transmembrane channel-like 5 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| USB1 | U6 snRNA biogenesis 1 |
| USP19 | ubiquitin specific peptidase 19 |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| VASH2 | vasohibin 2 |
| VAV1 | vav 1 guanine nucleotide exchange factor |
| WASF3 | WAS protein family, member 3 |
| WDR3 | WD repeat domain 3 |
| ZBTB25 | zinc finger and BTB domain containing 25 |
| ZNF134 | zinc finger protein 134 |
| ZNF239 | zinc finger protein 239 |
| ZNF365 | zinc finger protein 365 |
