| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hycanthone-5691 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ACTA2 | actin, alpha 2, smooth muscle, aorta |
| AK1 | adenylate kinase 1 |
| ANKRA2 | ankyrin repeat, family A (RFXANK-like), 2 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APOLD1 | apolipoprotein L domain containing 1 |
| AQP3 | aquaporin 3 (Gill blood group) |
| ATF3 | activating transcription factor 3 |
| BBC3 | BCL2 binding component 3 |
| BTG2 | BTG family, member 2 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CAMSAP1 | calmodulin regulated spectrin-associated protein 1 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| CCNG2 | cyclin G2 |
| CDC42EP3 | CDC42 effector protein (Rho GTPase binding) 3 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) |
| CDKN1C | cyclin-dependent kinase inhibitor 1C (p57, Kip2) |
| CEL | carboxyl ester lipase |
| CEP104 | centrosomal protein 104kDa |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CSNK2A2 | casein kinase 2, alpha prime polypeptide |
| CYLD | cylindromatosis (turban tumor syndrome) |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DFNB31 | deafness, autosomal recessive 31 |
| DPYSL4 | dihydropyrimidinase-like 4 |
| EPAS1 | endothelial PAS domain protein 1 |
| EPHA2 | EPH receptor A2 |
| FAM171A1 | family with sequence similarity 171, member A1 |
| FAM182B | family with sequence similarity 182, member B |
| FAS | Fas cell surface death receptor |
| FGFR3 | fibroblast growth factor receptor 3 |
| FOSL1 | FOS-like antigen 1 |
| FSCN1 | fascin actin-bundling protein 1 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GEM | GTP binding protein overexpressed in skeletal muscle |
| GLS | glutaminase |
| GLS2 | glutaminase 2 (liver, mitochondrial) |
| GNG13 | guanine nucleotide binding protein (G protein), gamma 13 |
| GPR35 | G protein-coupled receptor 35 |
| GPR87 | G protein-coupled receptor 87 |
| GUK1 | guanylate kinase 1 |
| H3F3B | H3 histone, family 3B (H3.3B) |
| HES2 | hes family bHLH transcription factor 2 |
| HEXIM1 | hexamethylene bis-acetamide inducible 1 |
| HIC2 | hypermethylated in cancer 2 |
| IFT27 | intraflagellar transport 27 |
| INPP1 | inositol polyphosphate-1-phosphatase |
| IRS2 | insulin receptor substrate 2 |
| JAG1 | jagged 1 |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| LIF | leukemia inhibitory factor |
| LIMK2 | LIM domain kinase 2 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MLLT11 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming |
| N4BP2L1 | NEDD4 binding protein 2-like 1 |
| NHLH2 | nescient helix loop helix 2 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| PDE4A | phosphodiesterase 4A, cAMP-specific |
| PIDD1 | p53-induced death domain protein 1 |
| PLCD1 | phospholipase C, delta 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAB1 | protein kinase, AMP-activated, beta 1 non-catalytic subunit |
| PTPRO | protein tyrosine phosphatase, receptor type, O |
| RAI2 | retinoic acid induced 2 |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RETN | resistin |
| RNF19B | ring finger protein 19B |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 |
| SERPINI1 | serpin peptidase inhibitor, clade I (neuroserpin), member 1 |
| SESN1 | sestrin 1 |
| SLAMF7 | SLAM family member 7 |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 |
| SOCS1 | suppressor of cytokine signaling 1 |
| SSX3 | synovial sarcoma, X breakpoint 3 |
| STK17A | serine/threonine kinase 17a |
| TBX3 | T-box 3 |
| TEX14 | testis expressed 14 |
| TLE2 | transducin-like enhancer of split 2 |
| TMEM144 | transmembrane protein 144 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 |
| TPMT | thiopurine S-methyltransferase |
| ZBTB18 | zinc finger and BTB domain containing 18 |
| ZCCHC24 | zinc finger, CCHC domain containing 24 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 |
| ZNF654 | zinc finger protein 654 |
| ZNF750 | zinc finger protein 750 |
| ZNF767P | zinc finger family member 767, pseudogene |
| ZNF79 | zinc finger protein 79 |
| Symbol | Name |
|---|---|
| ACTR8 | ARP8 actin-related protein 8 homolog (yeast) |
| ALS2CL | ALS2 C-terminal like |
| AMDHD2 | amidohydrolase domain containing 2 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 |
| BAG2 | BCL2-associated athanogene 2 |
| BCL9 | B-cell CLL/lymphoma 9 |
| BORA | bora, aurora kinase A activator |
| BPGM | 2,3-bisphosphoglycerate mutase |
| BRINP3 | bone morphogenetic protein/retinoic acid inducible neural-specific 3 |
| C3ORF52 | chromosome 3 open reading frame 52 |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CCP110 | centriolar coiled coil protein 110kDa |
| CCZ1B | CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae) |
| CHMP6 | charged multivesicular body protein 6 |
| DEPDC1 | DEP domain containing 1 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) |
| DLEU1 | deleted in lymphocytic leukemia 1 (non-protein coding) |
| DLEU2 | deleted in lymphocytic leukemia 2 (non-protein coding) |
| EXOSC9 | exosome component 9 |
| FAAH | fatty acid amide hydrolase |
| FAM86B1 | family with sequence similarity 86, member B1 |
| FANCL | Fanconi anemia, complementation group L |
| FBXO5 | F-box protein 5 |
| FILIP1L | filamin A interacting protein 1-like |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| FPGT | fucose-1-phosphate guanylyltransferase |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) |
| HIST1H1D | histone cluster 1, H1d |
| HIST1H2AJ | histone cluster 1, H2aj |
| HJURP | Holliday junction recognition protein |
| HSD17B11 | hydroxysteroid (17-beta) dehydrogenase 11 |
| HTR1E | 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled |
| ICE2 | interactor of little elongation complex ELL subunit 2 |
| KIAA0020 | KIAA0020 |
| KIF14 | kinesin family member 14 |
| KIF15 | kinesin family member 15 |
| LAMA3 | laminin, alpha 3 |
| LMBR1L | limb development membrane protein 1-like |
| LRRC20 | leucine rich repeat containing 20 |
| MANEA | mannosidase, endo-alpha |
| MATK | megakaryocyte-associated tyrosine kinase |
| MBD5 | methyl-CpG binding domain protein 5 |
| MCM3AP-AS1 | MCM3AP antisense RNA 1 |
| MDM4 | MDM4, p53 regulator |
| METTL1 | methyltransferase like 1 |
| MTR | 5-methyltetrahydrofolate-homocysteine methyltransferase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAA40 | N(alpha)-acetyltransferase 40, NatD catalytic subunit |
| NAP1L2 | nucleosome assembly protein 1-like 2 |
| NDC80 | NDC80 kinetochore complex component |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NFE2L3 | nuclear factor, erythroid 2-like 3 |
| NIPAL2 | NIPA-like domain containing 2 |
| NXPE3 | neurexophilin and PC-esterase domain family, member 3 |
| PAGR1 | PAXIP1 associated glutamate-rich protein 1 |
| PCDHB3 | protocadherin beta 3 |
| PLK1 | polo-like kinase 1 |
| PPAN | peter pan homolog (Drosophila) |
| PUS7L | pseudouridylate synthase 7 homolog (S. cerevisiae)-like |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| PYCRL | pyrroline-5-carboxylate reductase-like |
| RAB8B | RAB8B, member RAS oncogene family |
| RFTN1 | raftlin, lipid raft linker 1 |
| RNASEL | ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) |
| RNF2 | ring finger protein 2 |
| SIDT1 | SID1 transmembrane family, member 1 |
| SLC25A12 | solute carrier family 25 (aspartate/glutamate carrier), member 12 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 |
| SMEK2 | SMEK homolog 2, suppressor of mek1 (Dictyostelium) |
| SND1-IT1 | SND1 intronic transcript 1 |
| SP1 | Sp1 transcription factor |
| SP140L | SP140 nuclear body protein-like |
| SUOX | sulfite oxidase |
| TAF1A | TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa |
| TAOK1 | TAO kinase 1 |
| TCTN2 | tectonic family member 2 |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TMA16 | translation machinery associated 16 homolog (S. cerevisiae) |
| TMEM184C | transmembrane protein 184C |
| TOE1 | target of EGR1, member 1 (nuclear) |
| TRAF5 | TNF receptor-associated factor 5 |
| TROAP | trophinin associated protein |
| TSEN2 | TSEN2 tRNA splicing endonuclease subunit |
| USP18 | ubiquitin specific peptidase 18 |
| USP20 | ubiquitin specific peptidase 20 |
| VGF | VGF nerve growth factor inducible |
| XBP1 | X-box binding protein 1 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF141 | zinc finger protein 141 |
| ZNF227 | zinc finger protein 227 |
| ZNF248 | zinc finger protein 248 |
| ZNF571 | zinc finger protein 571 |
| ZNF573 | zinc finger protein 573 |
| ZNF692 | zinc finger protein 692 |
| ZNF778 | zinc finger protein 778 |
| ZNF83 | zinc finger protein 83 |
