| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the hydralazine-2349 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa |
| ARRB1 | arrestin, beta 1 |
| BMP7 | bone morphogenetic protein 7 |
| BMP8B | bone morphogenetic protein 8b |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CAMK2G | calcium/calmodulin-dependent protein kinase II gamma |
| CCPG1 | cell cycle progression 1 |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 |
| CDK13 | cyclin-dependent kinase 13 |
| CDK16 | cyclin-dependent kinase 16 |
| CHPF | chondroitin polymerizing factor |
| CNKSR2 | connector enhancer of kinase suppressor of Ras 2 |
| COPE | coatomer protein complex, subunit epsilon |
| COQ7 | coenzyme Q7 homolog, ubiquinone (yeast) |
| CPS1 | carbamoyl-phosphate synthase 1, mitochondrial |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog |
| DCAF15 | DDB1 and CUL4 associated factor 15 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAL4 | dynein, axonemal, light chain 4 |
| DPY19L1 | dpy-19-like 1 (C. elegans) |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| DTNA | dystrobrevin, alpha |
| E2F4 | E2F transcription factor 4, p107/p130-binding |
| ELK1 | ELK1, member of ETS oncogene family |
| ERAP2 | endoplasmic reticulum aminopeptidase 2 |
| FAM3A | family with sequence similarity 3, member A |
| GAL | galanin/GMAP prepropeptide |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GID4 | GID complex subunit 4 |
| GJB1 | gap junction protein, beta 1, 32kDa |
| GNS | glucosamine (N-acetyl)-6-sulfatase |
| GPR153 | G protein-coupled receptor 153 |
| HBB | hemoglobin, beta |
| HIST1H1T | histone cluster 1, H1t |
| HIST1H2BN | histone cluster 1, H2bn |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 |
| HN1L | hematological and neurological expressed 1-like |
| ICAM2 | intercellular adhesion molecule 2 |
| IFNAR1 | interferon (alpha, beta and omega) receptor 1 |
| IGHG1 | immunoglobulin heavy constant gamma 1 (G1m marker) |
| KDM4C | lysine (K)-specific demethylase 4C |
| KDM5A | lysine (K)-specific demethylase 5A |
| KIAA0753 | KIAA0753 |
| KMT2A | lysine (K)-specific methyltransferase 2A |
| LINC00597 | long intergenic non-protein coding RNA 597 |
| LTB | lymphotoxin beta (TNF superfamily, member 3) |
| MTCP1 | mature T-cell proliferation 1 |
| MXD3 | MAX dimerization protein 3 |
| NCALD | neurocalcin delta |
| NF1 | neurofibromin 1 |
| NLE1 | notchless homolog 1 (Drosophila) |
| NOTCH2 | notch 2 |
| NUAK1 | NUAK family, SNF1-like kinase, 1 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa |
| PDE4DIP | phosphodiesterase 4D interacting protein |
| PIAS3 | protein inhibitor of activated STAT, 3 |
| PLCD1 | phospholipase C, delta 1 |
| PLIN2 | perilipin 2 |
| PLSCR3 | phospholipid scramblase 3 |
| PRKAG2 | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
| PRLH | prolactin releasing hormone |
| PRMT2 | protein arginine methyltransferase 2 |
| PSD3 | pleckstrin and Sec7 domain containing 3 |
| PSG4 | pregnancy specific beta-1-glycoprotein 4 |
| PTH2R | parathyroid hormone 2 receptor |
| RALGDS | ral guanine nucleotide dissociation stimulator |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RGS12 | regulator of G-protein signaling 12 |
| RPAP1 | RNA polymerase II associated protein 1 |
| RUFY3 | RUN and FYVE domain containing 3 |
| SGSM2 | small G protein signaling modulator 2 |
| SIDT2 | SID1 transmembrane family, member 2 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor |
| SOCS2 | suppressor of cytokine signaling 2 |
| STBD1 | starch binding domain 1 |
| STC2 | stanniocalcin 2 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| TMCO3 | transmembrane and coiled-coil domains 3 |
| TMEM53 | transmembrane protein 53 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 |
| TP53I11 | tumor protein p53 inducible protein 11 |
| TPMT | thiopurine S-methyltransferase |
| URB1 | URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| USB1 | U6 snRNA biogenesis 1 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) |
| WDR60 | WD repeat domain 60 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZFX | zinc finger protein, X-linked |
| ZNF287 | zinc finger protein 287 |
| ZNF500 | zinc finger protein 500 |
| ZNF783 | zinc finger family member 783 |
| Symbol | Name |
|---|---|
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 |
| ACAD10 | acyl-CoA dehydrogenase family, member 10 |
| ADAP2 | ArfGAP with dual PH domains 2 |
| AGO4 | argonaute RISC catalytic component 4 |
| ALDOC | aldolase C, fructose-bisphosphate |
| APH1B | APH1B gamma secretase subunit |
| ATG9A | autophagy related 9A |
| AVPI1 | arginine vasopressin-induced 1 |
| BAG4 | BCL2-associated athanogene 4 |
| BAHCC1 | BAH domain and coiled-coil containing 1 |
| BTF3P12 | basic transcription factor 3 pseudogene 12 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C7ORF69 | chromosome 7 open reading frame 69 |
| CARD9 | caspase recruitment domain family, member 9 |
| CCDC109B | coiled-coil domain containing 109B |
| CDA | cytidine deaminase |
| CDC23 | cell division cycle 23 |
| CENPB | centromere protein B, 80kDa |
| CEP85 | centrosomal protein 85kDa |
| CIC | capicua transcriptional repressor |
| CIR1 | corepressor interacting with RBPJ, 1 |
| CYSLTR1 | cysteinyl leukotriene receptor 1 |
| ECSIT | ECSIT signalling integrator |
| EDAR | ectodysplasin A receptor |
| ELAC1 | elaC ribonuclease Z 1 |
| EXD2 | exonuclease 3'-5' domain containing 2 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FJX1 | four jointed box 1 (Drosophila) |
| FLJ21369 | uncharacterized protein FLJ21369 |
| GMPPA | GDP-mannose pyrophosphorylase A |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 |
| GPATCH2 | G patch domain containing 2 |
| GPR183 | G protein-coupled receptor 183 |
| IRF7 | interferon regulatory factor 7 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIF18A | kinesin family member 18A |
| LOC729164 | hCG1732469 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 |
| MAP4K3 | mitogen-activated protein kinase kinase kinase kinase 3 |
| MAP6D1 | MAP6 domain containing 1 |
| METTL21B | methyltransferase like 21B |
| MPZ | myelin protein zero |
| MTMR11 | myotubularin related protein 11 |
| MYL5 | myosin, light chain 5, regulatory |
| NARFL | nuclear prelamin A recognition factor-like |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NLRX1 | NLR family member X1 |
| NPFFR1 | neuropeptide FF receptor 1 |
| NRGN | neurogranin (protein kinase C substrate, RC3) |
| NTSR1 | neurotensin receptor 1 (high affinity) |
| OSGEPL1 | O-sialoglycoprotein endopeptidase-like 1 |
| PBX3 | pre-B-cell leukemia homeobox 3 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PDP1 | pyruvate dehyrogenase phosphatase catalytic subunit 1 |
| POLH | polymerase (DNA directed), eta |
| PRAF2 | PRA1 domain family, member 2 |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTPN4 | protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) |
| PWAR5 | Prader Willi/Angelman region RNA 5 |
| RAB8B | RAB8B, member RAS oncogene family |
| RBBP5 | retinoblastoma binding protein 5 |
| RBM47 | RNA binding motif protein 47 |
| RNF121 | ring finger protein 121 |
| RPA4 | replication protein A4, 30kDa |
| SETD1A | SET domain containing 1A |
| SKI | SKI proto-oncogene |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 |
| SMR3A | submaxillary gland androgen regulated protein 3A |
| SNRPN | small nuclear ribonucleoprotein polypeptide N |
| SPATA2L | spermatogenesis associated 2-like |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STAG3 | stromal antigen 3 |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TBXAS1 | thromboxane A synthase 1 (platelet) |
| TIGD6 | tigger transposable element derived 6 |
| TM7SF2 | transmembrane 7 superfamily member 2 |
| TMC7 | transmembrane channel-like 7 |
| TMEM185B | transmembrane protein 185B |
| TMEM212 | transmembrane protein 212 |
| TMEM254 | transmembrane protein 254 |
| TMOD3 | tropomodulin 3 (ubiquitous) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRIM22 | tripartite motif containing 22 |
| TUBGCP5 | tubulin, gamma complex associated protein 5 |
| URGCP | upregulator of cell proliferation |
| USP5 | ubiquitin specific peptidase 5 (isopeptidase T) |
| WDR62 | WD repeat domain 62 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZBTB48 | zinc finger and BTB domain containing 48 |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF16 | zinc finger protein 16 |
| ZNF280D | zinc finger protein 280D |
| ZNF669 | zinc finger protein 669 |
| ZNF701 | zinc finger protein 701 |
| ZSCAN16 | zinc finger and SCAN domain containing 16 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |