| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hydralazine-4746 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AASS | aminoadipate-semialdehyde synthase |
| ADAMDEC1 | ADAM-like, decysin 1 |
| AKAP7 | A kinase (PRKA) anchor protein 7 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 |
| ATRNL1 | attractin-like 1 |
| C1ORF54 | chromosome 1 open reading frame 54 |
| C3ORF18 | chromosome 3 open reading frame 18 |
| CARD10 | caspase recruitment domain family, member 10 |
| CD44 | CD44 molecule (Indian blood group) |
| CD70 | CD70 molecule |
| CLTC | clathrin, heavy chain (Hc) |
| CNR2 | cannabinoid receptor 2 (macrophage) |
| CPED1 | cadherin-like and PC-esterase domain containing 1 |
| CST4 | cystatin S |
| CTSE | cathepsin E |
| CTSZ | cathepsin Z |
| CXCR4 | chemokine (C-X-C motif) receptor 4 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 |
| DCLK2 | doublecortin-like kinase 2 |
| EVI2B | ecotropic viral integration site 2B |
| FASLG | Fas ligand (TNF superfamily, member 6) |
| FBN2 | fibrillin 2 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FGB | fibrinogen beta chain |
| FYB | FYN binding protein |
| GABRD | gamma-aminobutyric acid (GABA) A receptor, delta |
| GAP43 | growth associated protein 43 |
| GAS7 | growth arrest-specific 7 |
| GIF | gastric intrinsic factor (vitamin B synthesis) |
| GLS | glutaminase |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GRIA3 | glutamate receptor, ionotropic, AMPA 3 |
| GRIP2 | glutamate receptor interacting protein 2 |
| HIST1H3I | histone cluster 1, H3i |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 |
| HMGN5 | high mobility group nucleosome binding domain 5 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HOXB5 | homeobox B5 |
| IBA57 | IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae) |
| IFI6 | interferon, alpha-inducible protein 6 |
| INO80D | INO80 complex subunit D |
| INTS1 | integrator complex subunit 1 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 |
| JAK3 | Janus kinase 3 |
| KCNIP1 | Kv channel interacting protein 1 |
| KCNJ14 | potassium channel, inwardly rectifying subfamily J, member 14 |
| KCNK10 | potassium channel, two pore domain subfamily K, member 10 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 |
| KIF25-AS1 | KIF25 antisense RNA 1 |
| LOC440895 | two pore channel 3 pseudogene |
| LOXL3 | lysyl oxidase-like 3 |
| LST1 | leukocyte specific transcript 1 |
| MAOA | monoamine oxidase A |
| MAPK10 | mitogen-activated protein kinase 10 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MBD2 | methyl-CpG binding domain protein 2 |
| MEF2C | myocyte enhancer factor 2C |
| MSR1 | macrophage scavenger receptor 1 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NAG18 | NAG18 mRNA |
| NRXN3 | neurexin 3 |
| OR1A2 | olfactory receptor, family 1, subfamily A, member 2 |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PAEP | progestagen-associated endometrial protein |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 |
| PHF1 | PHD finger protein 1 |
| PKD1 | polycystic kidney disease 1 (autosomal dominant) |
| PNMAL1 | paraneoplastic Ma antigen family-like 1 |
| POM121 | POM121 transmembrane nucleoporin |
| PRKAA2 | protein kinase, AMP-activated, alpha 2 catalytic subunit |
| PTCH2 | patched 2 |
| PTGER3 | prostaglandin E receptor 3 (subtype EP3) |
| PTN | pleiotrophin |
| RAB40C | RAB40C, member RAS oncogene family |
| RAC2 | ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2) |
| RARA | retinoic acid receptor, alpha |
| RBBP4 | retinoblastoma binding protein 4 |
| REC8 | REC8 meiotic recombination protein |
| RPH3A | rabphilin 3A |
| SGCD | sarcoglycan, delta (35kDa dystrophin-associated glycoprotein) |
| SLA | Src-like-adaptor |
| SLC17A7 | solute carrier family 17 (vesicular glutamate transporter), member 7 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) |
| SRSF7 | serine/arginine-rich splicing factor 7 |
| TBX21 | T-box 21 |
| TCF4 | transcription factor 4 |
| TCL6 | T-cell leukemia/lymphoma 6 (non-protein coding) |
| TFEB | transcription factor EB |
| TGFBR3 | transforming growth factor, beta receptor III |
| THRA | thyroid hormone receptor, alpha |
| TTLL5 | tubulin tyrosine ligase-like family member 5 |
| WDR78 | WD repeat domain 78 |
| WISP3 | WNT1 inducible signaling pathway protein 3 |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| XYLB | xylulokinase homolog (H. influenzae) |
| YY2 | YY2 transcription factor |
| ZNF440 | zinc finger protein 440 |
| Symbol | Name |
|---|---|
| ABCA11P | ATP-binding cassette, sub-family A (ABC1), member 11, pseudogene |
| ALS2CL | ALS2 C-terminal like |
| ANKFY1 | ankyrin repeat and FYVE domain containing 1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| AUTS2 | autism susceptibility candidate 2 |
| BAX | BCL2-associated X protein |
| C2ORF27A | chromosome 2 open reading frame 27A |
| CABYR | calcium binding tyrosine-(Y)-phosphorylation regulated |
| CCDC186 | coiled-coil domain containing 186 |
| CD82 | CD82 molecule |
| CEP131 | centrosomal protein 131kDa |
| CES3 | carboxylesterase 3 |
| CLDN1 | claudin 1 |
| CLDN15 | claudin 15 |
| COL4A3BP | collagen, type IV, alpha 3 (Goodpasture antigen) binding protein |
| CRYBG3 | beta-gamma crystallin domain containing 3 |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| CXADR | coxsackie virus and adenovirus receptor |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEF6 | differentially expressed in FDCP 6 homolog (mouse) |
| DOCK4 | dedicator of cytokinesis 4 |
| ELP6 | elongator acetyltransferase complex subunit 6 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| FAM131A | family with sequence similarity 131, member A |
| FBXW12 | F-box and WD repeat domain containing 12 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase |
| FKBP1B | FK506 binding protein 1B, 12.6 kDa |
| FKBP5 | FK506 binding protein 5 |
| FKRP | fukutin related protein |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GID4 | GID complex subunit 4 |
| GMEB1 | glucocorticoid modulatory element binding protein 1 |
| GSTCD | glutathione S-transferase, C-terminal domain containing |
| GTF2A1 | general transcription factor IIA, 1, 19/37kDa |
| GTF2F2 | general transcription factor IIF, polypeptide 2, 30kDa |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H2AI | histone cluster 1, H2ai |
| HMOX1 | heme oxygenase 1 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IFT54 | intraflagellar transport 54 |
| IL17RA | interleukin 17 receptor A |
| KIAA0125 | KIAA0125 |
| KIFC1 | kinesin family member C1 |
| LHX6 | LIM homeobox 6 |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| MCOLN3 | mucolipin 3 |
| MDM4 | MDM4, p53 regulator |
| MTA2 | metastasis associated 1 family, member 2 |
| MXD3 | MAX dimerization protein 3 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) |
| NPIPB15 | nuclear pore complex interacting protein family, member B15 |
| NR1H3 | nuclear receptor subfamily 1, group H, member 3 |
| NT5DC3 | 5'-nucleotidase domain containing 3 |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PHEX | phosphate regulating endopeptidase homolog, X-linked |
| PIM1 | Pim-1 proto-oncogene, serine/threonine kinase |
| PLA2G4C | phospholipase A2, group IVC (cytosolic, calcium-independent) |
| PRPH | peripherin |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 |
| RCBTB2 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 |
| RNF123 | ring finger protein 123 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RRNAD1 | ribosomal RNA adenine dimethylase domain containing 1 |
| S100A4 | S100 calcium binding protein A4 |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SPRY2 | sprouty homolog 2 (Drosophila) |
| SPRYD7 | SPRY domain containing 7 |
| ST3GAL5 | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 |
| STBD1 | starch binding domain 1 |
| STX5 | syntaxin 5 |
| TEP1 | telomerase-associated protein 1 |
| THBS3 | thrombospondin 3 |
| THRAP3 | thyroid hormone receptor associated protein 3 |
| TMEM209 | transmembrane protein 209 |
| TMEM242 | transmembrane protein 242 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRIM36 | tripartite motif containing 36 |
| TRMU | tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase |
| TSPAN1 | tetraspanin 1 |
| UNC93B1 | unc-93 homolog B1 (C. elegans) |
| USB1 | U6 snRNA biogenesis 1 |
| WDR76 | WD repeat domain 76 |
| ZNF350 | zinc finger protein 350 |
| ZNF480 | zinc finger protein 480 |
| ZNF669 | zinc finger protein 669 |
| ZNF675 | zinc finger protein 675 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |