| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
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195 genes differentially expressed following the hydrastinine-2119 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| ANP32A | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A |
| APC | adenomatous polyposis coli |
| APOBEC3G | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G |
| ARHGEF4 | Rho guanine nucleotide exchange factor (GEF) 4 |
| ARMCX4 | armadillo repeat containing, X-linked 4 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BST1 | bone marrow stromal cell antigen 1 |
| C16ORF59 | chromosome 16 open reading frame 59 |
| C1S | complement component 1, s subcomponent |
| CABP5 | calcium binding protein 5 |
| CASP5 | caspase 5, apoptosis-related cysteine peptidase |
| CASZ1 | castor zinc finger 1 |
| CCL27 | chemokine (C-C motif) ligand 27 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 |
| DGKE | diacylglycerol kinase, epsilon 64kDa |
| DNAJB12 | DnaJ (Hsp40) homolog, subfamily B, member 12 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EDA | ectodysplasin A |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ESRRA | estrogen-related receptor alpha |
| FCF1 | FCF1 rRNA-processing protein |
| GABBR2 | gamma-aminobutyric acid (GABA) B receptor, 2 |
| GAS7 | growth arrest-specific 7 |
| GLB1L2 | galactosidase, beta 1-like 2 |
| GSK3A | glycogen synthase kinase 3 alpha |
| GTF3C2 | general transcription factor IIIC, polypeptide 2, beta 110kDa |
| GUCY1B3 | guanylate cyclase 1, soluble, beta 3 |
| HTR4 | 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 |
| INVS | inversin |
| KCNAB2 | potassium channel, voltage gated subfamily A regulatory beta subunit 2 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 |
| LMNA | lamin A/C |
| LMNB1 | lamin B1 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MAP1A | microtubule-associated protein 1A |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| METTL16 | methyltransferase like 16 |
| METTL5 | methyltransferase like 5 |
| MGAT2 | mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| MIIP | migration and invasion inhibitory protein |
| MINK1 | misshapen-like kinase 1 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MOCS1 | molybdenum cofactor synthesis 1 |
| MTSS1L | metastasis suppressor 1-like |
| MVK | mevalonate kinase |
| NDST1 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 |
| NR2C1 | nuclear receptor subfamily 2, group C, member 1 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 |
| NRF1 | nuclear respiratory factor 1 |
| PALM | paralemmin |
| PARVA | parvin, alpha |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 |
| PICALM | phosphatidylinositol binding clathrin assembly protein |
| PIGC | phosphatidylinositol glycan anchor biosynthesis, class C |
| PKP3 | plakophilin 3 |
| PLCG1 | phospholipase C, gamma 1 |
| PRKCA | protein kinase C, alpha |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) |
| RANBP1 | RAN binding protein 1 |
| RARA | retinoic acid receptor, alpha |
| RNF121 | ring finger protein 121 |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 |
| RTEL1 | regulator of telomere elongation helicase 1 |
| RUNX1 | runt-related transcription factor 1 |
| RUNX3 | runt-related transcription factor 3 |
| SETD1A | SET domain containing 1A |
| SFT2D2 | SFT2 domain containing 2 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SLN | sarcolipin |
| SOS2 | son of sevenless homolog 2 (Drosophila) |
| STK16 | serine/threonine kinase 16 |
| SULT1A2 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2 |
| SUSD4 | sushi domain containing 4 |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TBKBP1 | TBK1 binding protein 1 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) |
| TIAM1 | T-cell lymphoma invasion and metastasis 1 |
| TIMM17A | translocase of inner mitochondrial membrane 17 homolog A (yeast) |
| TLE4 | transducin-like enhancer of split 4 |
| TREX1 | three prime repair exonuclease 1 |
| TRIM23 | tripartite motif containing 23 |
| TRIM25 | tripartite motif containing 25 |
| TSNAXIP1 | translin-associated factor X interacting protein 1 |
| TTC38 | tetratricopeptide repeat domain 38 |
| UBOX5 | U-box domain containing 5 |
| VGLL1 | vestigial-like family member 1 |
| YTHDC1 | YTH domain containing 1 |
| ZFHX3 | zinc finger homeobox 3 |
| ZFP69B | ZFP69 zinc finger protein B |
| ZNF358 | zinc finger protein 358 |
| ZNF37BP | zinc finger protein 37B, pseudogene |
| Symbol | Name |
|---|---|
| ACIN1 | apoptotic chromatin condensation inducer 1 |
| ADAMTS3 | ADAM metallopeptidase with thrombospondin type 1 motif, 3 |
| ANGPTL4 | angiopoietin-like 4 |
| ANKRD27 | ankyrin repeat domain 27 (VPS9 domain) |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| ARHGAP11A | Rho GTPase activating protein 11A |
| ARRB2 | arrestin, beta 2 |
| ATG9A | autophagy related 9A |
| BGLAP | bone gamma-carboxyglutamate (gla) protein |
| C1ORF105 | chromosome 1 open reading frame 105 |
| C5ORF30 | chromosome 5 open reading frame 30 |
| CABIN1 | calcineurin binding protein 1 |
| CDK5RAP2 | CDK5 regulatory subunit associated protein 2 |
| CHMP6 | charged multivesicular body protein 6 |
| CLSPN | claspin |
| CORO1A | coronin, actin binding protein, 1A |
| CPSF4 | cleavage and polyadenylation specific factor 4, 30kDa |
| CTDP1 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 |
| CUTC | cutC copper transporter |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DDX54 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 54 |
| DEAF1 | DEAF1 transcription factor |
| DFNB31 | deafness, autosomal recessive 31 |
| DMTF1 | cyclin D binding myb-like transcription factor 1 |
| EDEM1 | ER degradation enhancer, mannosidase alpha-like 1 |
| EIF5A2 | eukaryotic translation initiation factor 5A2 |
| ERF | Ets2 repressor factor |
| EVPL | envoplakin |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLCN | folliculin |
| FOXA1 | forkhead box A1 |
| GABBR1 | gamma-aminobutyric acid (GABA) B receptor, 1 |
| GLCE | glucuronic acid epimerase |
| GLDC | glycine dehydrogenase (decarboxylating) |
| GMCL1 | germ cell-less, spermatogenesis associated 1 |
| GUSBP3 | glucuronidase, beta pseudogene 3 |
| HAUS6 | HAUS augmin-like complex, subunit 6 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 |
| HIRA | histone cell cycle regulator |
| HIST1H2AG | histone cluster 1, H2ag |
| ICK | intestinal cell (MAK-like) kinase |
| IFT22 | intraflagellar transport 22 |
| IL4R | interleukin 4 receptor |
| KIF20B | kinesin family member 20B |
| KIF3B | kinesin family member 3B |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LIAS | lipoic acid synthetase |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LRRC8E | leucine rich repeat containing 8 family, member E |
| MANSC1 | MANSC domain containing 1 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial |
| MED9 | mediator complex subunit 9 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MX1 | MX dynamin-like GTPase 1 |
| MYBBP1A | MYB binding protein (P160) 1a |
| NABP2 | nucleic acid binding protein 2 |
| P3H4 | prolyl 3-hydroxylase family member 4 (non-enzymatic) |
| PARP16 | poly (ADP-ribose) polymerase family, member 16 |
| PCYOX1 | prenylcysteine oxidase 1 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PHACTR4 | phosphatase and actin regulator 4 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PLCB3 | phospholipase C, beta 3 (phosphatidylinositol-specific) |
| PLEKHA6 | pleckstrin homology domain containing, family A member 6 |
| PLEKHM2 | pleckstrin homology domain containing, family M (with RUN domain) member 2 |
| POLQ | polymerase (DNA directed), theta |
| PPFIA3 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RBL1 | retinoblastoma-like 1 |
| RCBTB1 | regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1 |
| SFMBT1 | Scm-like with four mbt domains 1 |
| SLC1A3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| SLC25A40 | solute carrier family 25, member 40 |
| SLC35C2 | solute carrier family 35 (GDP-fucose transporter), member C2 |
| SMA4 | glucuronidase, beta pseudogene |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TLN1 | talin 1 |
| TOR4A | torsin family 4, member A |
| TRIM16 | tripartite motif containing 16 |
| TRIM21 | tripartite motif containing 21 |
| TSPAN12 | tetraspanin 12 |
| UBQLN4 | ubiquilin 4 |
| VPS33A | vacuolar protein sorting 33 homolog A (S. cerevisiae) |
| ZKSCAN3 | zinc finger with KRAB and SCAN domains 3 |
| ZNF107 | zinc finger protein 107 |
| ZNF254 | zinc finger protein 254 |
| ZNF408 | zinc finger protein 408 |
| ZNF430 | zinc finger protein 430 |
| ZNF611 | zinc finger protein 611 |
| ZNF652 | zinc finger protein 652 |
| ZNF721 | zinc finger protein 721 |
| ZNF767P | zinc finger family member 767, pseudogene |