hydrocotarnine-2765 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the hydrocotarnine-2765 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A2M alpha-2-macroglobulin
A4GNT alpha-1,4-N-acetylglucosaminyltransferase
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDOB aldolase B, fructose-bisphosphate
ANKRD12 ankyrin repeat domain 12
ANP32A-IT1 ANP32A intronic transcript 1
AOC3 amine oxidase, copper containing 3
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APOBEC3C apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3C
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAIAP3 BAI1-associated protein 3
BAX BCL2-associated X protein
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF16 chromosome 11 open reading frame 16
C21ORF2 chromosome 21 open reading frame 2
CAPN5 calpain 5
CD7 CD7 molecule
CEMIP cell migration inducing protein, hyaluronan binding
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIC capicua transcriptional repressor
CUZD1 CUB and zona pellucida-like domains 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DICER1 dicer 1, ribonuclease type III
DIO2 deiodinase, iodothyronine, type II
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGLN3 egl-9 family hypoxia-inducible factor 3
EHBP1L1 EH domain binding protein 1-like 1
FFAR2 free fatty acid receptor 2
FLJ11292
FN1 fibronectin 1
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GAST gastrin
GGT1 gamma-glutamyltransferase 1
GMPR guanosine monophosphate reductase
GPM6B glycoprotein M6B
HDAC7 histone deacetylase 7
HLA-DMA major histocompatibility complex, class II, DM alpha
HLA-DQB1 major histocompatibility complex, class II, DQ beta 1
HOXA10 homeobox A10
HSPB11 heat shock protein family B (small), member 11
IL2RG interleukin 2 receptor, gamma
KAZN kazrin, periplakin interacting protein
KIAA0319L KIAA0319-like
KRT15 keratin 15, type I
LTB4R leukotriene B4 receptor
MAST2 microtubule associated serine/threonine kinase 2
MEF2D myocyte enhancer factor 2D
MINK1 misshapen-like kinase 1
MUC1 mucin 1, cell surface associated
MYOF myoferlin
NBL1 neuroblastoma 1, DAN family BMP antagonist
NF2 neurofibromin 2 (merlin)
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NUP54 nucleoporin 54kDa
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PCSK6 proprotein convertase subtilisin/kexin type 6
PDE1C phosphodiesterase 1C, calmodulin-dependent 70kDa
PDE4C phosphodiesterase 4C, cAMP-specific
PDLIM5 PDZ and LIM domain 5
PIDD1 p53-induced death domain protein 1
PPFIA3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
PSD4 pleckstrin and Sec7 domain containing 4
RGS10 regulator of G-protein signaling 10
RNF17 ring finger protein 17
RNF39 ring finger protein 39
RPH3A rabphilin 3A
RPL35A ribosomal protein L35a
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A9 S100 calcium binding protein A9
SH2D3A SH2 domain containing 3A
SIGLEC6 sialic acid binding Ig-like lectin 6
SIM2 single-minded family bHLH transcription factor 2
SIRT5 sirtuin 5
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SNTA1 syntrophin, alpha 1
SPEF1 sperm flagellar 1
SSPN sarcospan
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STMN1 stathmin 1
SYT2 synaptotagmin II
TFF2 trefoil factor 2
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
TM4SF1 transmembrane 4 L six family member 1
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TREX1 three prime repair exonuclease 1
UNC93B1 unc-93 homolog B1 (C. elegans)
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIZ widely interspaced zinc finger motifs
WSCD1 WSC domain containing 1
XDH xanthine dehydrogenase
YIPF2 Yip1 domain family, member 2
ZC2HC1C zinc finger, C2HC-type containing 1C
ZFAND5 zinc finger, AN1-type domain 5
ZNF250 zinc finger protein 250
ZNF3 zinc finger protein 3
ZNF639 zinc finger protein 639
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ABHD3 abhydrolase domain containing 3
ACSF2 acyl-CoA synthetase family member 2
AES amino-terminal enhancer of split
ARL15 ADP-ribosylation factor-like 15
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BGLAP bone gamma-carboxyglutamate (gla) protein
C11ORF80 chromosome 11 open reading frame 80
C16ORF59 chromosome 16 open reading frame 59
CALCOCO1 calcium binding and coiled-coil domain 1
CBX7 chromobox homolog 7
CDK3 cyclin-dependent kinase 3
CHRM3 cholinergic receptor, muscarinic 3
CHST10 carbohydrate sulfotransferase 10
CLDND1 claudin domain containing 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CYB5R1 cytochrome b5 reductase 1
DBF4B DBF4 zinc finger B
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DNAJC24 DnaJ (Hsp40) homolog, subfamily C, member 24
EHMT2 euchromatic histone-lysine N-methyltransferase 2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM172A family with sequence similarity 172, member A
FAM188A family with sequence similarity 188, member A
FAM189A2 family with sequence similarity 189, member A2
FAM50B family with sequence similarity 50, member B
FOCAD focadhesin
GALT galactose-1-phosphate uridylyltransferase
GLI3 GLI family zinc finger 3
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
H1F0 H1 histone family, member 0
HPS6 Hermansky-Pudlak syndrome 6
HSPA1L heat shock 70kDa protein 1-like
IPO8 importin 8
IPP intracisternal A particle-promoted polypeptide
IRAK4 interleukin-1 receptor-associated kinase 4
IRF9 interferon regulatory factor 9
ISYNA1 inositol-3-phosphate synthase 1
KCTD7 potassium channel tetramerization domain containing 7
LAMA3 laminin, alpha 3
LOC390998 ribosomal protein L10 pseudogene
LPXN leupaxin
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAN2C1 mannosidase, alpha, class 2C, member 1
MGMT O-6-methylguanine-DNA methyltransferase
MITF microphthalmia-associated transcription factor
MPI mannose phosphate isomerase
MPP5 membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase
NES nestin
NIPAL2 NIPA-like domain containing 2
NPFFR1 neuropeptide FF receptor 1
ONECUT2 one cut homeobox 2
OSMR oncostatin M receptor
PC pyruvate carboxylase
PDZD8 PDZ domain containing 8
PILRB paired immunoglobin-like type 2 receptor beta
PIM1 Pim-1 proto-oncogene, serine/threonine kinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPM1E protein phosphatase, Mg2+/Mn2+ dependent, 1E
PPP1R3C protein phosphatase 1, regulatory subunit 3C
RAB30 RAB30, member RAS oncogene family
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
RNF126P1 ring finger protein 126 pseudogene 1
RPUSD2 RNA pseudouridylate synthase domain containing 2
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
SH2B3 SH2B adaptor protein 3
SIRT2 sirtuin 2
SNORA21 small nucleolar RNA, H/ACA box 21
SP1 Sp1 transcription factor
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STK16 serine/threonine kinase 16
STX1A syntaxin 1A (brain)
THBS3 thrombospondin 3
TMEM121 transmembrane protein 121
TMEM184C transmembrane protein 184C
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TTLL1 tubulin tyrosine ligase-like family member 1
TTPAL tocopherol (alpha) transfer protein-like
TWISTNB TWIST neighbor
ULBP2 UL16 binding protein 2
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
ZBED8 zinc finger, BED-type containing 8
ZBTB44 zinc finger and BTB domain containing 44
ZDHHC11 zinc finger, DHHC-type containing 11
ZNF10 zinc finger protein 10
ZNF143 zinc finger protein 143
ZNF16 zinc finger protein 16
ZNF211 zinc finger protein 211
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31