| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hydroflumethiazide-1809 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 |
| ACYP1 | acylphosphatase 1, erythrocyte (common) type |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| ALDH4A1 | aldehyde dehydrogenase 4 family, member A1 |
| AP1S1 | adaptor-related protein complex 1, sigma 1 subunit |
| APBA3 | amyloid beta (A4) precursor protein-binding, family A, member 3 |
| APP | amyloid beta (A4) precursor protein |
| ARL6IP4 | ADP-ribosylation factor-like 6 interacting protein 4 |
| B9D1 | B9 protein domain 1 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B |
| BCL2L2 | BCL2-like 2 |
| BRWD1 | bromodomain and WD repeat domain containing 1 |
| C17ORF75 | chromosome 17 open reading frame 75 |
| C1ORF115 | chromosome 1 open reading frame 115 |
| C9ORF116 | chromosome 9 open reading frame 116 |
| CACNG4 | calcium channel, voltage-dependent, gamma subunit 4 |
| CALD1 | caldesmon 1 |
| CASKIN2 | CASK interacting protein 2 |
| CCNA1 | cyclin A1 |
| COL6A1 | collagen, type VI, alpha 1 |
| CTSZ | cathepsin Z |
| CYB561 | cytochrome b561 |
| DAZAP2 | DAZ associated protein 2 |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) |
| ESR1 | estrogen receptor 1 |
| ETNK1 | ethanolamine kinase 1 |
| FOXO1 | forkhead box O1 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| GEMIN4 | gem (nuclear organelle) associated protein 4 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GLRB | glycine receptor, beta |
| H1F0 | H1 histone family, member 0 |
| HEMK1 | HemK methyltransferase family member 1 |
| HMGB3 | high mobility group box 3 |
| HMGB3P1 | high mobility group box 3 pseudogene 1 |
| HNMT | histamine N-methyltransferase |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| ING4 | inhibitor of growth family, member 4 |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| JUN | jun proto-oncogene |
| KANK1 | KN motif and ankyrin repeat domains 1 |
| LIN7C | lin-7 homolog C (C. elegans) |
| LMNB1 | lamin B1 |
| LRRC37A3 | leucine rich repeat containing 37, member A3 |
| LTBP1 | latent transforming growth factor beta binding protein 1 |
| LYPD3 | LY6/PLAUR domain containing 3 |
| MDFI | MyoD family inhibitor |
| ME1 | malic enzyme 1, NADP(+)-dependent, cytosolic |
| MED6 | mediator complex subunit 6 |
| MEX3D | mex-3 RNA binding family member D |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) |
| MT1F | metallothionein 1F |
| MYL4 | myosin, light chain 4, alkali; atrial, embryonic |
| NDUFAF7 | NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 |
| NNT | nicotinamide nucleotide transhydrogenase |
| NPAS2 | neuronal PAS domain protein 2 |
| PBX2 | pre-B-cell leukemia homeobox 2 |
| PCID2 | PCI domain containing 2 |
| PDCL | phosducin-like |
| PEX11A | peroxisomal biogenesis factor 11 alpha |
| PHF3 | PHD finger protein 3 |
| PLCG1 | phospholipase C, gamma 1 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit |
| PRKD3 | protein kinase D3 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) |
| RAD51D | RAD51 paralog D |
| RARS | arginyl-tRNA synthetase |
| RB1CC1 | RB1-inducible coiled-coil 1 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 |
| RC3H2 | ring finger and CCCH-type domains 2 |
| SBF1 | SET binding factor 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SEMA4C | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 |
| SLC39A7 | solute carrier family 39 (zinc transporter), member 7 |
| SMAD3 | SMAD family member 3 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) |
| SRRM2 | serine/arginine repetitive matrix 2 |
| STK16 | serine/threonine kinase 16 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TAP2 | transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) |
| TCF4 | transcription factor 4 |
| TMCO1 | transmembrane and coiled-coil domains 1 |
| TRADD | TNFRSF1A-associated via death domain |
| TRIO | trio Rho guanine nucleotide exchange factor |
| UEVLD | UEV and lactate/malate dehyrogenase domains |
| ZNF146 | zinc finger protein 146 |
| ZNF277 | zinc finger protein 277 |
| ZNF358 | zinc finger protein 358 |
| Symbol | Name |
|---|---|
| ALG12 | ALG12, alpha-1,6-mannosyltransferase |
| ALPK1 | alpha-kinase 1 |
| APBB1 | amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ARMC6 | armadillo repeat containing 6 |
| ARSJ | arylsulfatase family, member J |
| BANK1 | B-cell scaffold protein with ankyrin repeats 1 |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C6ORF47 | chromosome 6 open reading frame 47 |
| C7ORF43 | chromosome 7 open reading frame 43 |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CISH | cytokine inducible SH2-containing protein |
| CLCF1 | cardiotrophin-like cytokine factor 1 |
| CLCN2 | chloride channel, voltage-sensitive 2 |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| COQ4 | coenzyme Q4 |
| CST4 | cystatin S |
| CTSO | cathepsin O |
| CWF19L1 | CWF19-like 1, cell cycle control (S. pombe) |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 |
| DCLRE1A | DNA cross-link repair 1A |
| DDX31 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 31 |
| DHX35 | DEAH (Asp-Glu-Ala-His) box polypeptide 35 |
| E4F1 | E4F transcription factor 1 |
| EDC4 | enhancer of mRNA decapping 4 |
| ETNK2 | ethanolamine kinase 2 |
| FBXL2 | F-box and leucine-rich repeat protein 2 |
| FGD1 | FYVE, RhoGEF and PH domain containing 1 |
| FLJ22184 | |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) |
| FZD8 | frizzled class receptor 8 |
| GBF1 | golgi brefeldin A resistant guanine nucleotide exchange factor 1 |
| GIT1 | G protein-coupled receptor kinase interacting ArfGAP 1 |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRWD1 | glutamate-rich WD repeat containing 1 |
| HDAC7 | histone deacetylase 7 |
| HLX | H2.0-like homeobox |
| IGFLR1 | IGF-like family receptor 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KCTD15 | potassium channel tetramerization domain containing 15 |
| KIFC3 | kinesin family member C3 |
| LAMC3 | laminin, gamma 3 |
| LRP5L | low density lipoprotein receptor-related protein 5-like |
| MAGEF1 | melanoma antigen family F1 |
| MAPK12 | mitogen-activated protein kinase 12 |
| MED9 | mediator complex subunit 9 |
| MFSD11 | major facilitator superfamily domain containing 11 |
| MX1 | MX dynamin-like GTPase 1 |
| NOTCH1 | notch 1 |
| NOX5 | NADPH oxidase, EF-hand calcium binding domain 5 |
| NUBP2 | nucleotide binding protein 2 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PACSIN3 | protein kinase C and casein kinase substrate in neurons 3 |
| PILRB | paired immunoglobin-like type 2 receptor beta |
| PLD2 | phospholipase D2 |
| POLR3D | polymerase (RNA) III (DNA directed) polypeptide D, 44kDa |
| PTTG3P | pituitary tumor-transforming 3, pseudogene |
| RAB3A | RAB3A, member RAS oncogene family |
| RBL1 | retinoblastoma-like 1 |
| RBM42 | RNA binding motif protein 42 |
| RIN1 | Ras and Rab interactor 1 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase |
| RUNX1-IT1 | RUNX1 intronic transcript 1 |
| RUSC2 | RUN and SH3 domain containing 2 |
| SALL2 | spalt-like transcription factor 2 |
| SCAMP4 | secretory carrier membrane protein 4 |
| SCARA3 | scavenger receptor class A, member 3 |
| SCML2 | sex comb on midleg-like 2 (Drosophila) |
| SEC14L2 | SEC14-like 2 (S. cerevisiae) |
| SH3GL1 | SH3-domain GRB2-like 1 |
| SHPK | sedoheptulokinase |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC29A2 | solute carrier family 29 (equilibrative nucleoside transporter), member 2 |
| SLC2A6 | solute carrier family 2 (facilitated glucose transporter), member 6 |
| SLC2A8 | solute carrier family 2 (facilitated glucose transporter), member 8 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STAG3 | stromal antigen 3 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| SYT17 | synaptotagmin XVII |
| TAGLN3 | transgelin 3 |
| TMC7 | transmembrane channel-like 7 |
| TMEM132A | transmembrane protein 132A |
| TOLLIP | toll interacting protein |
| TPCN1 | two pore segment channel 1 |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TSC22D4 | TSC22 domain family, member 4 |
| USP19 | ubiquitin specific peptidase 19 |
| USP32 | ubiquitin specific peptidase 32 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF215 | zinc finger protein 215 |
| ZNF32 | zinc finger protein 32 |
| ZNF580 | zinc finger protein 580 |
| ZNF747 | zinc finger protein 747 |
| ZNF85 | zinc finger protein 85 |
