| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hydroflumethiazide-1851 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABHD6 | abhydrolase domain containing 6 |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AFF2 | AF4/FMR2 family, member 2 |
| APOC1 | apolipoprotein C-I |
| ARFRP1 | ADP-ribosylation factor related protein 1 |
| ARHGAP1 | Rho GTPase activating protein 1 |
| BACE1 | beta-site APP-cleaving enzyme 1 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B |
| BBS9 | Bardet-Biedl syndrome 9 |
| BGN | biglycan |
| BICD1 | bicaudal D homolog 1 (Drosophila) |
| BMP15 | bone morphogenetic protein 15 |
| C17ORF80 | chromosome 17 open reading frame 80 |
| C5ORF45 | chromosome 5 open reading frame 45 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CD59 | CD59 molecule, complement regulatory protein |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) |
| CEP295 | centrosomal protein 295kDa |
| CES3 | carboxylesterase 3 |
| CSF1 | colony stimulating factor 1 (macrophage) |
| CSF2RA | colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage) |
| CTSH | cathepsin H |
| CUL3 | cullin 3 |
| CYB561 | cytochrome b561 |
| DCTN2 | dynactin 2 (p50) |
| DFNA5 | deafness, autosomal dominant 5 |
| DRD2 | dopamine receptor D2 |
| DSTYK | dual serine/threonine and tyrosine protein kinase |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| FN1 | fibronectin 1 |
| FOSL2 | FOS-like antigen 2 |
| GNRH1 | gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) |
| GOLGA2 | golgin A2 |
| HDAC7 | histone deacetylase 7 |
| HSDL2 | hydroxysteroid dehydrogenase like 2 |
| ICOSLG | inducible T-cell co-stimulator ligand |
| IQSEC1 | IQ motif and Sec7 domain 1 |
| KCNA3 | potassium channel, voltage gated shaker related subfamily A, member 3 |
| KDM5C | lysine (K)-specific demethylase 5C |
| KIF1A | kinesin family member 1A |
| L3MBTL1 | l(3)mbt-like 1 (Drosophila) |
| LAMB2 | laminin, beta 2 (laminin S) |
| LILRB3 | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 |
| LPCAT4 | lysophosphatidylcholine acyltransferase 4 |
| MAGED2 | melanoma antigen family D2 |
| MAL | mal, T-cell differentiation protein |
| MC1R | melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor) |
| MCC | mutated in colorectal cancers |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 |
| MTMR3 | myotubularin related protein 3 |
| MYO1B | myosin IB |
| MYOF | myoferlin |
| NF1 | neurofibromin 1 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NIPAL3 | NIPA-like domain containing 3 |
| NPC1 | Niemann-Pick disease, type C1 |
| NRG2 | neuregulin 2 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAFAH2 | platelet-activating factor acetylhydrolase 2, 40kDa |
| PDAP1 | PDGFA associated protein 1 |
| PENK | proenkephalin |
| PEX5 | peroxisomal biogenesis factor 5 |
| PLAA | phospholipase A2-activating protein |
| PLAT | plasminogen activator, tissue |
| PLCD1 | phospholipase C, delta 1 |
| PLSCR3 | phospholipid scramblase 3 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| PPM1A | protein phosphatase, Mg2+/Mn2+ dependent, 1A |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha |
| PRICKLE3 | prickle homolog 3 (Drosophila) |
| PRMT2IP | PRMT2 interacting protein |
| PROS1 | protein S (alpha) |
| PTGDS | prostaglandin D2 synthase 21kDa (brain) |
| RASA3 | RAS p21 protein activator 3 |
| RHOB | ras homolog family member B |
| RPL5 | ribosomal protein L5 |
| RRAGB | Ras-related GTP binding B |
| SFTPC | surfactant protein C |
| SIGLEC7 | sialic acid binding Ig-like lectin 7 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) |
| SOGA1 | suppressor of glucose, autophagy associated 1 |
| SOX15 | SRY (sex determining region Y)-box 15 |
| SRCAP | Snf2-related CREBBP activator protein |
| ST8SIA3 | ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 |
| STMN1 | stathmin 1 |
| TAF6L | TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor, 65kDa |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b |
| TSC22D4 | TSC22 domain family, member 4 |
| TSPYL2 | TSPY-like 2 |
| UBIAD1 | UbiA prenyltransferase domain containing 1 |
| ZNF43 | zinc finger protein 43 |
| ZNF696 | zinc finger protein 696 |
| Symbol | Name |
|---|---|
| AAR2 | AAR2 splicing factor homolog (S. cerevisiae) |
| ACYP2 | acylphosphatase 2, muscle type |
| AMIGO2 | adhesion molecule with Ig-like domain 2 |
| AP5S1 | adaptor-related protein complex 5, sigma 1 subunit |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARNTL2 | aryl hydrocarbon receptor nuclear translocator-like 2 |
| ASB6 | ankyrin repeat and SOCS box containing 6 |
| AUP1 | ancient ubiquitous protein 1 |
| BIN3 | bridging integrator 3 |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C2CD2 | C2 calcium-dependent domain containing 2 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CD302 | CD302 molecule |
| CDK9 | cyclin-dependent kinase 9 |
| CENPT | centromere protein T |
| CHEK1 | checkpoint kinase 1 |
| CHMP6 | charged multivesicular body protein 6 |
| CHST10 | carbohydrate sulfotransferase 10 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 |
| CINP | cyclin-dependent kinase 2 interacting protein |
| COQ4 | coenzyme Q4 |
| COX6B1 | cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) |
| CYB5R1 | cytochrome b5 reductase 1 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 |
| DEF8 | differentially expressed in FDCP 8 homolog (mouse) |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 |
| DZANK1 | double zinc ribbon and ankyrin repeat domains 1 |
| EMC9 | ER membrane protein complex subunit 9 |
| FEM1C | fem-1 homolog c (C. elegans) |
| GALK2 | galactokinase 2 |
| GIN1 | gypsy retrotransposon integrase 1 |
| GLTP | glycolipid transfer protein |
| GPATCH3 | G patch domain containing 3 |
| HDAC3 | histone deacetylase 3 |
| HELZ | helicase with zinc finger |
| IFITM3 | interferon induced transmembrane protein 3 |
| IKZF5 | IKAROS family zinc finger 5 (Pegasus) |
| IRAK4 | interleukin-1 receptor-associated kinase 4 |
| KATNBL1 | katanin p80 subunit B-like 1 |
| KLHL26 | kelch-like family member 26 |
| KRBOX4 | KRAB box domain containing 4 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 |
| LXN | latexin |
| MAPK3 | mitogen-activated protein kinase 3 |
| MBTD1 | mbt domain containing 1 |
| MBTPS2 | membrane-bound transcription factor peptidase, site 2 |
| MDM4 | MDM4, p53 regulator |
| MED9 | mediator complex subunit 9 |
| MON1B | MON1 secretory trafficking family member B |
| MPDU1 | mannose-P-dolichol utilization defect 1 |
| MPI | mannose phosphate isomerase |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A |
| MTCH2 | mitochondrial carrier 2 |
| MUM1 | melanoma associated antigen (mutated) 1 |
| MX2 | MX dynamin-like GTPase 2 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 |
| NCKAP1L | NCK-associated protein 1-like |
| NTHL1 | nth endonuclease III-like 1 (E. coli) |
| PGM3 | phosphoglucomutase 3 |
| PIBF1 | progesterone immunomodulatory binding factor 1 |
| PIP4K2C | phosphatidylinositol-5-phosphate 4-kinase, type II, gamma |
| PJA1 | praja ring finger 1, E3 ubiquitin protein ligase |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor |
| PPIP5K2 | diphosphoinositol pentakisphosphate kinase 2 |
| PTDSS2 | phosphatidylserine synthase 2 |
| RARS | arginyl-tRNA synthetase |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RFNG | RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase |
| RIC8B | RIC8 guanine nucleotide exchange factor B |
| RNF113A | ring finger protein 113A |
| RNF2 | ring finger protein 2 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| S100A12 | S100 calcium binding protein A12 |
| SHFM1 | split hand/foot malformation (ectrodactyly) type 1 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SRD5A3 | steroid 5 alpha-reductase 3 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) |
| SUV39H1 | suppressor of variegation 3-9 homolog 1 (Drosophila) |
| TEC | tec protein tyrosine kinase |
| TOLLIP | toll interacting protein |
| TRAPPC6A | trafficking protein particle complex 6A |
| TRIM25 | tripartite motif containing 25 |
| TTF2 | transcription termination factor, RNA polymerase II |
| TUBA3C | tubulin, alpha 3c |
| TULP4 | tubby like protein 4 |
| UBE2O | ubiquitin-conjugating enzyme E2O |
| VILL | villin-like |
| WDR19 | WD repeat domain 19 |
| WT1-AS | WT1 antisense RNA |
| WWC2 | WW and C2 domain containing 2 |
| ZFYVE16 | zinc finger, FYVE domain containing 16 |
| ZNF134 | zinc finger protein 134 |
| ZNF302 | zinc finger protein 302 |
| ZNF804A | zinc finger protein 804A |
