| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hydroflumethiazide-7019 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADAM18 | ADAM metallopeptidase domain 18 |
| ADRA1D | adrenoceptor alpha 1D |
| AHCYL2 | adenosylhomocysteinase-like 2 |
| AMT | aminomethyltransferase |
| ARHGAP35 | Rho GTPase activating protein 35 |
| ARHGEF11 | Rho guanine nucleotide exchange factor (GEF) 11 |
| ARL4D | ADP-ribosylation factor-like 4D |
| ATP10A | ATPase, class V, type 10A |
| C16ORF58 | chromosome 16 open reading frame 58 |
| C1QTNF1 | C1q and tumor necrosis factor related protein 1 |
| CADPS2 | Ca++-dependent secretion activator 2 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase |
| CCPG1 | cell cycle progression 1 |
| CD6 | CD6 molecule |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 |
| CHST5 | carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5 |
| CNTN5 | contactin 5 |
| COL5A2 | collagen, type V, alpha 2 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 |
| DGAT1 | diacylglycerol O-acyltransferase 1 |
| DIO2 | deiodinase, iodothyronine, type II |
| DOK2 | docking protein 2, 56kDa |
| DPYSL4 | dihydropyrimidinase-like 4 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 |
| ELK4 | ELK4, ETS-domain protein (SRF accessory protein 1) |
| ELOVL5 | ELOVL fatty acid elongase 5 |
| EMID1 | EMI domain containing 1 |
| ENTPD4 | ectonucleoside triphosphate diphosphohydrolase 4 |
| ESR1 | estrogen receptor 1 |
| FBXO11 | F-box protein 11 |
| FGFR1 | fibroblast growth factor receptor 1 |
| FZD7 | frizzled class receptor 7 |
| GGA1 | golgi-associated, gamma adaptin ear containing, ARF binding protein 1 |
| GHRHR | growth hormone releasing hormone receptor |
| GUCY1B2 | guanylate cyclase 1, soluble, beta 2 (pseudogene) |
| HCRP1 | hepatocellular carcinoma-related HCRP1 |
| HLA-J | major histocompatibility complex, class I, J (pseudogene) |
| HNRNPA3P1 | heterogeneous nuclear ribonucleoprotein A3 pseudogene 1 |
| ING1 | inhibitor of growth family, member 1 |
| ING4 | inhibitor of growth family, member 4 |
| INPP5J | inositol polyphosphate-5-phosphatase J |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) |
| JMJD4 | jumonji domain containing 4 |
| KLHL28 | kelch-like family member 28 |
| KRAS | Kirsten rat sarcoma viral oncogene homolog |
| KRTAP9-9 | keratin associated protein 9-9 |
| LOC730101 | uncharacterized LOC730101 |
| LONRF3 | LON peptidase N-terminal domain and ring finger 3 |
| LZTR1 | leucine-zipper-like transcription regulator 1 |
| MAP2K5 | mitogen-activated protein kinase kinase 5 |
| MEGF9 | multiple EGF-like-domains 9 |
| MKL1 | megakaryoblastic leukemia (translocation) 1 |
| MMP19 | matrix metallopeptidase 19 |
| MTAP | methylthioadenosine phosphorylase |
| MTMR3 | myotubularin related protein 3 |
| MYF5 | myogenic factor 5 |
| NDE1 | nudE neurodevelopment protein 1 |
| NDST2 | N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 |
| NDUFB8 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa |
| NF1 | neurofibromin 1 |
| NF2 | neurofibromin 2 (merlin) |
| NR2E3 | nuclear receptor subfamily 2, group E, member 3 |
| NUDCD3 | NudC domain containing 3 |
| PAX5 | paired box 5 |
| PCDHA5 | protocadherin alpha 5 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited |
| PDGFB | platelet-derived growth factor beta polypeptide |
| PEX5 | peroxisomal biogenesis factor 5 |
| PHC1 | polyhomeotic homolog 1 (Drosophila) |
| PHF20 | PHD finger protein 20 |
| PIDD1 | p53-induced death domain protein 1 |
| PIN1 | peptidylprolyl cis/trans isomerase, NIMA-interacting 1 |
| PLEKHF1 | pleckstrin homology domain containing, family F (with FYVE domain) member 1 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 |
| PLEKHO2 | pleckstrin homology domain containing, family O member 2 |
| PRAMEF12 | PRAME family member 12 |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RABEP1 | rabaptin, RAB GTPase binding effector protein 1 |
| RNF126P1 | ring finger protein 126 pseudogene 1 |
| RRN3P1 | RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1 |
| SCAPER | S-phase cyclin A-associated protein in the ER |
| SH2B3 | SH2B adaptor protein 3 |
| SIM2 | single-minded family bHLH transcription factor 2 |
| SLC17A2 | solute carrier family 17, member 2 |
| SLC38A7 | solute carrier family 38, member 7 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa |
| SPSB3 | splA/ryanodine receptor domain and SOCS box containing 3 |
| STAB2 | stabilin 2 |
| TCF3 | transcription factor 3 |
| TEF | thyrotrophic embryonic factor |
| TFPI2 | tissue factor pathway inhibitor 2 |
| TLE2 | transducin-like enhancer of split 2 |
| TLE4 | transducin-like enhancer of split 4 |
| YIPF4 | Yip1 domain family, member 4 |
| ZNF134 | zinc finger protein 134 |
| ZNF141 | zinc finger protein 141 |
| ZNF324 | zinc finger protein 324 |
| ZNF446 | zinc finger protein 446 |
| ZNF45 | zinc finger protein 45 |
| ZNF573 | zinc finger protein 573 |
| Symbol | Name |
|---|---|
| ABHD4 | abhydrolase domain containing 4 |
| ACVR2A | activin A receptor, type IIA |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARRB2 | arrestin, beta 2 |
| ATAD2B | ATPase family, AAA domain containing 2B |
| ATAD5 | ATPase family, AAA domain containing 5 |
| ATP11B | ATPase, class VI, type 11B |
| BHLHB9 | basic helix-loop-helix domain containing, class B, 9 |
| C21ORF91 | chromosome 21 open reading frame 91 |
| C2ORF44 | chromosome 2 open reading frame 44 |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CARD8 | caspase recruitment domain family, member 8 |
| CASZ1 | castor zinc finger 1 |
| CCNL2 | cyclin L2 |
| CCS | copper chaperone for superoxide dismutase |
| CDC42BPB | CDC42 binding protein kinase beta (DMPK-like) |
| CDKN2AIP | CDKN2A interacting protein |
| CDR2L | cerebellar degeneration-related protein 2-like |
| CEP85 | centrosomal protein 85kDa |
| CERK | ceramide kinase |
| CISH | cytokine inducible SH2-containing protein |
| CLN6 | ceroid-lipofuscinosis, neuronal 6, late infantile, variant |
| CLSPN | claspin |
| CXORF56 | chromosome X open reading frame 56 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DDX43 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
| DVL1 | dishevelled segment polarity protein 1 |
| DYNC2H1 | dynein, cytoplasmic 2, heavy chain 1 |
| EFCAB2 | EF-hand calcium binding domain 2 |
| FANCE | Fanconi anemia, complementation group E |
| FBXO22 | F-box protein 22 |
| FOSL1 | FOS-like antigen 1 |
| GAN | gigaxonin |
| GIT2 | G protein-coupled receptor kinase interacting ArfGAP 2 |
| HIST1H2AE | histone cluster 1, H2ae |
| HIST1H2AJ | histone cluster 1, H2aj |
| IPPK | inositol 1,3,4,5,6-pentakisphosphate 2-kinase |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) |
| KIZ | kizuna centrosomal protein |
| KLF3 | Kruppel-like factor 3 (basic) |
| KRT13 | keratin 13, type I |
| KRT8P12 | keratin 8 pseudogene 12 |
| LAMA3 | laminin, alpha 3 |
| LIN37 | lin-37 DREAM MuvB core complex component |
| LINS | lines homolog (Drosophila) |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP7D1 | MAP7 domain containing 1 |
| MED24 | mediator complex subunit 24 |
| MEX3C | mex-3 RNA binding family member C |
| MGAT1 | mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase |
| NCAM2 | neural cell adhesion molecule 2 |
| NMU | neuromedin U |
| OPA3 | optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PC | pyruvate carboxylase |
| PELI1 | pellino E3 ubiquitin protein ligase 1 |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POP1 | processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae) |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| RASSF1 | Ras association (RalGDS/AF-6) domain family member 1 |
| RHBDF2 | rhomboid 5 homolog 2 (Drosophila) |
| RNF123 | ring finger protein 123 |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| SCAP | SREBF chaperone |
| SHARPIN | SHANK-associated RH domain interactor |
| SLC22A5 | solute carrier family 22 (organic cation/carnitine transporter), member 5 |
| SLC25A23 | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23 |
| SNHG20 | small nucleolar RNA host gene 20 |
| SOX3 | SRY (sex determining region Y)-box 3 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBC1D12 | TBC1 domain family, member 12 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) |
| TESK1 | testis-specific kinase 1 |
| TGFB3 | transforming growth factor, beta 3 |
| TIMM10B | translocase of inner mitochondrial membrane 10 homolog B (yeast) |
| TMEM184C | transmembrane protein 184C |
| TNRC6B | trinucleotide repeat containing 6B |
| TPST1 | tyrosylprotein sulfotransferase 1 |
| TPST2 | tyrosylprotein sulfotransferase 2 |
| TRAF4 | TNF receptor-associated factor 4 |
| TRAPPC13 | trafficking protein particle complex 13 |
| TTC4 | tetratricopeptide repeat domain 4 |
| TTLL1 | tubulin tyrosine ligase-like family member 1 |
| VWA1 | von Willebrand factor A domain containing 1 |
| WDR13 | WD repeat domain 13 |
| XPNPEP3 | X-prolyl aminopeptidase 3, mitochondrial |
| ZNF14 | zinc finger protein 14 |
| ZNF35 | zinc finger protein 35 |
| ZNF586 | zinc finger protein 586 |
| ZNF675 | zinc finger protein 675 |
| ZNF692 | zinc finger protein 692 |
| ZSCAN9 | zinc finger and SCAN domain containing 9 |
