| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hydroflumethiazide-7259 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ABCB8 | ATP-binding cassette, sub-family B (MDR/TAP), member 8 |
| ADRBK1 | adrenergic, beta, receptor kinase 1 |
| AKR1C2 | aldo-keto reductase family 1, member C2 |
| ANKMY1 | ankyrin repeat and MYND domain containing 1 |
| BAX | BCL2-associated X protein |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) |
| BEX4 | brain expressed, X-linked 4 |
| BRD4 | bromodomain containing 4 |
| BTN3A3 | butyrophilin, subfamily 3, member A3 |
| C10ORF88 | chromosome 10 open reading frame 88 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 |
| CDC25C | cell division cycle 25C |
| CDKN2D | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) |
| CEP68 | centrosomal protein 68kDa |
| CLUHP3 | clustered mitochondria (cluA/CLU1) homolog pseudogene 3 |
| CNPPD1 | cyclin Pas1/PHO80 domain containing 1 |
| CNTNAP2 | contactin associated protein-like 2 |
| COL6A1 | collagen, type VI, alpha 1 |
| COX15 | cytochrome c oxidase assembly homolog 15 (yeast) |
| CYP2E1 | cytochrome P450, family 2, subfamily E, polypeptide 1 |
| DNAJC28 | DnaJ (Hsp40) homolog, subfamily C, member 28 |
| DNAJC8 | DnaJ (Hsp40) homolog, subfamily C, member 8 |
| EFEMP2 | EGF containing fibulin-like extracellular matrix protein 2 |
| ERGIC3 | ERGIC and golgi 3 |
| ESR1 | estrogen receptor 1 |
| F11R | F11 receptor |
| FBN2 | fibrillin 2 |
| FLJ10038 | uncharacterized protein FLJ10038 |
| FLJ11292 | |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 |
| GALK2 | galactokinase 2 |
| GNAZ | guanine nucleotide binding protein (G protein), alpha z polypeptide |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial |
| IL15RA | interleukin 15 receptor, alpha |
| INCENP | inner centromere protein antigens 135/155kDa |
| INO80B | INO80 complex subunit B |
| INPP5B | inositol polyphosphate-5-phosphatase, 75kDa |
| KLK10 | kallikrein-related peptidase 10 |
| KRIT1 | KRIT1, ankyrin repeat containing |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MED16 | mediator complex subunit 16 |
| MITF | microphthalmia-associated transcription factor |
| MMP13 | matrix metallopeptidase 13 |
| MYO1F | myosin IF |
| NCOR2 | nuclear receptor corepressor 2 |
| NEK3 | NIMA-related kinase 3 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) |
| NNMT | nicotinamide N-methyltransferase |
| NOVA1 | neuro-oncological ventral antigen 1 |
| NRP1 | neuropilin 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP62CL | nucleoporin 62kDa C-terminal like |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PARP3 | poly (ADP-ribose) polymerase family, member 3 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PEX7 | peroxisomal biogenesis factor 7 |
| POLL | polymerase (DNA directed), lambda |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPIL2 | peptidylprolyl isomerase (cyclophilin)-like 2 |
| RAB29 | RAB29, member RAS oncogene family |
| RAD52 | RAD52 homolog (S. cerevisiae) |
| RGS12 | regulator of G-protein signaling 12 |
| SCN1B | sodium channel, voltage gated, type I beta subunit |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 |
| SERTAD3 | SERTA domain containing 3 |
| SETD6 | SET domain containing 6 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) |
| SLC12A9 | solute carrier family 12, member 9 |
| SLC26A6 | solute carrier family 26 (anion exchanger), member 6 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SPP1 | secreted phosphoprotein 1 |
| SRPX2 | sushi-repeat containing protein, X-linked 2 |
| SS18 | synovial sarcoma translocation, chromosome 18 |
| STK16 | serine/threonine kinase 16 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 |
| SURF1 | surfeit 1 |
| TEAD3 | TEA domain family member 3 |
| TESK2 | testis-specific kinase 2 |
| TEX40 | testis expressed 40 |
| THAP3 | THAP domain containing, apoptosis associated protein 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TMC5 | transmembrane channel-like 5 |
| TMEM212 | transmembrane protein 212 |
| TOX | thymocyte selection-associated high mobility group box |
| TRIM23 | tripartite motif containing 23 |
| TRIO | trio Rho guanine nucleotide exchange factor |
| TRMT2A | tRNA methyltransferase 2 homolog A (S. cerevisiae) |
| TXNRD2 | thioredoxin reductase 2 |
| VARS | valyl-tRNA synthetase |
| WNT16 | wingless-type MMTV integration site family, member 16 |
| YTHDC2 | YTH domain containing 2 |
| ZBTB22 | zinc finger and BTB domain containing 22 |
| ZCWPW1 | zinc finger, CW type with PWWP domain 1 |
| ZEB1 | zinc finger E-box binding homeobox 1 |
| ZFYVE9 | zinc finger, FYVE domain containing 9 |
| ZNF224 | zinc finger protein 224 |
| ZNF84 | zinc finger protein 84 |
| Symbol | Name |
|---|---|
| ACTG2 | actin, gamma 2, smooth muscle, enteric |
| AP1AR | adaptor-related protein complex 1 associated regulatory protein |
| AP1B1 | adaptor-related protein complex 1, beta 1 subunit |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit |
| BCAS3 | breast carcinoma amplified sequence 3 |
| BIRC3 | baculoviral IAP repeat containing 3 |
| C1R | complement component 1, r subcomponent |
| C7ORF43 | chromosome 7 open reading frame 43 |
| C8ORF60 | chromosome 8 open reading frame 60 |
| C9ORF91 | chromosome 9 open reading frame 91 |
| CFD | complement factor D (adipsin) |
| CLSPN | claspin |
| CSRNP3 | cysteine-serine-rich nuclear protein 3 |
| CXORF56 | chromosome X open reading frame 56 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 |
| DET1 | de-etiolated homolog 1 (Arabidopsis) |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 |
| DLL3 | delta-like 3 (Drosophila) |
| DTWD1 | DTW domain containing 1 |
| DYNC1I1 | dynein, cytoplasmic 1, intermediate chain 1 |
| DYSF | dysferlin |
| EFCAB2 | EF-hand calcium binding domain 2 |
| EN1 | engrailed homeobox 1 |
| EVL | Enah/Vasp-like |
| FAM188A | family with sequence similarity 188, member A |
| FSTL3 | follistatin-like 3 (secreted glycoprotein) |
| FXN | frataxin |
| GJC1 | gap junction protein, gamma 1, 45kDa |
| GLCE | glucuronic acid epimerase |
| GNB1L | guanine nucleotide binding protein (G protein), beta polypeptide 1-like |
| GRPR | gastrin-releasing peptide receptor |
| GTF3C5 | general transcription factor IIIC, polypeptide 5, 63kDa |
| HMHA1 | histocompatibility (minor) HA-1 |
| HSPB8 | heat shock 22kDa protein 8 |
| ITGB2 | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) |
| JMJD4 | jumonji domain containing 4 |
| JUNB | jun B proto-oncogene |
| KCTD20 | potassium channel tetramerization domain containing 20 |
| KIAA0556 | KIAA0556 |
| KPTN | kaptin (actin binding protein) |
| KRT4 | keratin 4, type II |
| LINC00339 | long intergenic non-protein coding RNA 339 |
| MTMR11 | myotubularin related protein 11 |
| MTRF1 | mitochondrial translational release factor 1 |
| NAG18 | NAG18 mRNA |
| NDE1 | nudE neurodevelopment protein 1 |
| NECAP2 | NECAP endocytosis associated 2 |
| OCLN | occludin |
| OTUB2 | OTU deubiquitinase, ubiquitin aldehyde binding 2 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PALMD | palmdelphin |
| PAM16 | presequence translocase-associated motor 16 homolog (S. cerevisiae) |
| PARD6A | par-6 family cell polarity regulator alpha |
| PDLIM2 | PDZ and LIM domain 2 (mystique) |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| POLR1B | polymerase (RNA) I polypeptide B, 128kDa |
| PRKAB2 | protein kinase, AMP-activated, beta 2 non-catalytic subunit |
| PTCD2 | pentatricopeptide repeat domain 2 |
| RAB11B | RAB11B, member RAS oncogene family |
| RPL23AP32 | ribosomal protein L23a pseudogene 32 |
| RPS6KA4 | ribosomal protein S6 kinase, 90kDa, polypeptide 4 |
| SDF2 | stromal cell-derived factor 2 |
| SESN1 | sestrin 1 |
| SH3BGR | SH3 domain binding glutamate-rich protein |
| SIAH2 | siah E3 ubiquitin protein ligase 2 |
| SLC12A8 | solute carrier family 12, member 8 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SLC25A10 | solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10 |
| SLC29A3 | solute carrier family 29 (equilibrative nucleoside transporter), member 3 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SP140L | SP140 nuclear body protein-like |
| SPEG | SPEG complex locus |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 |
| STIM1 | stromal interaction molecule 1 |
| SUGCT | succinyl-CoA:glutarate-CoA transferase |
| TBC1D19 | TBC1 domain family, member 19 |
| TESPA1 | thymocyte expressed, positive selection associated 1 |
| TMEM177 | transmembrane protein 177 |
| TOMM40 | translocase of outer mitochondrial membrane 40 homolog (yeast) |
| TRAF6 | TNF receptor-associated factor 6, E3 ubiquitin protein ligase |
| TRAIP | TRAF interacting protein |
| TRIM52 | tripartite motif containing 52 |
| TRPM2 | transient receptor potential cation channel, subfamily M, member 2 |
| TSPYL2 | TSPY-like 2 |
| TUBA3C | tubulin, alpha 3c |
| USP27X | ubiquitin specific peptidase 27, X-linked |
| WDR18 | WD repeat domain 18 |
| XPA | xeroderma pigmentosum, complementation group A |
| XPC | xeroderma pigmentosum, complementation group C |
| ZNF669 | zinc finger protein 669 |
| ZNF696 | zinc finger protein 696 |
| ZNF770 | zinc finger protein 770 |
| ZNF816 | zinc finger protein 816 |
| ZNF862 | zinc finger protein 862 |
| ZSCAN31 | zinc finger and SCAN domain containing 31 |
