hydrops fetalis Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description The abnormal accumulation of fluid in two or more fetal compartments, including ascites, pleural effusion, pericardial effusion, and skin edema. (Human Phenotype Ontology, HP_0001789)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0002192
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Genes

73 gene mutations causing the hydrops fetalis phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ADAMTS6 ADAM metallopeptidase with thrombospondin type 1 motif, 6
ADM adrenomedullin
ARF6 ADP-ribosylation factor 6
ARID2 AT rich interactive domain 2 (ARID, RFX-like)
ATP11A ATPase, class VI, type 11A
B9D2 B9 protein domain 2
CALCRL calcitonin receptor-like
CBX1 chromobox homolog 1
CC2D2A coiled-coil and C2 domain containing 2A
CCDC134 coiled-coil domain containing 134
CHRD chordin
CHTOP chromatin target of PRMT1
CIR1 corepressor interacting with RBPJ, 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CSNK2A1 casein kinase 2, alpha 1 polypeptide
CXCR4 chemokine (C-X-C motif) receptor 4
CYFIP2 cytoplasmic FMR1 interacting protein 2
DPH1 diphthamide biosynthesis 1
ECE1 endothelin converting enzyme 1
EHD1 EH-domain containing 1
EZR ezrin
FES FES proto-oncogene, tyrosine kinase
FLT4 fms-related tyrosine kinase 4
FOXC1 forkhead box C1
FOXM1 forkhead box M1
FOXP1 forkhead box P1
GATA4 GATA binding protein 4
GLDC glycine dehydrogenase (decarboxylating)
GNAS GNAS complex locus
HLX H2.0-like homeobox
IGF1R insulin-like growth factor 1 receptor
KIF1BP KIF1 binding protein
KIFAP3 kinesin-associated protein 3
LHX2 LIM homeobox 2
LIX1L Lix1 homolog (chicken) like
LZTR1 leucine-zipper-like transcription regulator 1
MARCH5 membrane-associated ring finger (C3HC4) 5
MTFMT mitochondrial methionyl-tRNA formyltransferase
NF1 neurofibromin 1
NPR1 natriuretic peptide receptor 1
OSR1 odd-skipped related transciption factor 1
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDGFRB platelet-derived growth factor receptor, beta polypeptide
PDS5B PDS5 cohesin associated factor B
PFKL phosphofructokinase, liver
PHF20 PHD finger protein 20
PKD1 polycystic kidney disease 1 (autosomal dominant)
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLXNB2 plexin B2
PODXL podocalyxin-like
PTPN11 protein tyrosine phosphatase, non-receptor type 11
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase
RICTOR RPTOR independent companion of MTOR, complex 2
RIPK4 receptor-interacting serine-threonine kinase 4
SOX4 SRY (sex determining region Y)-box 4
SPTBN1 spectrin, beta, non-erythrocytic 1
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
SYK spleen tyrosine kinase
SYMPK symplekin
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TBX1 T-box 1
TBX2 T-box 2
TBX5 T-box 5
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TFRC transferrin receptor
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TSC1 tuberous sclerosis 1
USP3 ubiquitin specific peptidase 3
VEGFC vascular endothelial growth factor C
ZEB1 zinc finger E-box binding homeobox 1
ZFPM2 zinc finger protein, FOG family member 2