| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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198 genes differentially expressed following the hydroquinine-1775 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| AAMDC | adipogenesis associated, Mth938 domain containing |
| ACAN | aggrecan |
| ADAM8 | ADAM metallopeptidase domain 8 |
| ADRBK2 | adrenergic, beta, receptor kinase 2 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) |
| ALDH3B1 | aldehyde dehydrogenase 3 family, member B1 |
| APOC1 | apolipoprotein C-I |
| ASB13 | ankyrin repeat and SOCS box containing 13 |
| ATG4B | autophagy related 4B, cysteine peptidase |
| ATXN7 | ataxin 7 |
| BAX | BCL2-associated X protein |
| BCL2L14 | BCL2-like 14 (apoptosis facilitator) |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 |
| CLPTM1 | cleft lip and palate associated transmembrane protein 1 |
| CR1 | complement component (3b/4b) receptor 1 (Knops blood group) |
| CTRC | chymotrypsin C (caldecrin) |
| DGCR8 | DGCR8 microprocessor complex subunit |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 |
| DNM2 | dynamin 2 |
| DUS2 | dihydrouridine synthase 2 |
| DUSP6 | dual specificity phosphatase 6 |
| DXO | decapping exoribonuclease |
| EFNB3 | ephrin-B3 |
| EPN2 | epsin 2 |
| ERN2 | endoplasmic reticulum to nucleus signaling 2 |
| EXTL3 | exostosin-like glycosyltransferase 3 |
| FANCA | Fanconi anemia, complementation group A |
| FDX1 | ferredoxin 1 |
| FTH1 | ferritin, heavy polypeptide 1 |
| GABPB1 | GA binding protein transcription factor, beta subunit 1 |
| GCLM | glutamate-cysteine ligase, modifier subunit |
| GLI3 | GLI family zinc finger 3 |
| GLS | glutaminase |
| GNL1 | guanine nucleotide binding protein-like 1 |
| GPX3 | glutathione peroxidase 3 |
| GRK6 | G protein-coupled receptor kinase 6 |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| IL27RA | interleukin 27 receptor, alpha |
| JRK | Jrk homolog (mouse) |
| JUP | junction plakoglobin |
| KCNH2 | potassium channel, voltage gated eag related subfamily H, member 2 |
| KLHL21 | kelch-like family member 21 |
| LMF2 | lipase maturation factor 2 |
| LUZP1 | leucine zipper protein 1 |
| MARK4 | MAP/microtubule affinity-regulating kinase 4 |
| MAST2 | microtubule associated serine/threonine kinase 2 |
| MDC1 | mediator of DNA-damage checkpoint 1 |
| MED16 | mediator complex subunit 16 |
| MED20 | mediator complex subunit 20 |
| MED28 | mediator complex subunit 28 |
| MEF2A | myocyte enhancer factor 2A |
| MFSD12 | major facilitator superfamily domain containing 12 |
| MTF1 | metal-regulatory transcription factor 1 |
| MTM1 | myotubularin 1 |
| NAAA | N-acylethanolamine acid amidase |
| NCR2 | natural cytotoxicity triggering receptor 2 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
| OR2H2 | olfactory receptor, family 2, subfamily H, member 2 |
| PARG | poly (ADP-ribose) glycohydrolase |
| PELP1 | proline, glutamate and leucine rich protein 1 |
| PEX16 | peroxisomal biogenesis factor 16 |
| PIAS2 | protein inhibitor of activated STAT, 2 |
| PLK3 | polo-like kinase 3 |
| POLG | polymerase (DNA directed), gamma |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 |
| PPP1R3D | protein phosphatase 1, regulatory subunit 3D |
| PRAMEF11 | PRAME family member 11 |
| PRDM4 | PR domain containing 4 |
| PSMD11 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 11 |
| PSPN | persephin |
| RACGAP1 | Rac GTPase activating protein 1 |
| RHOT2 | ras homolog family member T2 |
| RNF2 | ring finger protein 2 |
| RPL10 | ribosomal protein L10 |
| RXRA | retinoid X receptor, alpha |
| SBF1 | SET binding factor 1 |
| SEMA4G | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 |
| SMG5 | SMG5 nonsense mediated mRNA decay factor |
| SMIM8 | small integral membrane protein 8 |
| SNAPC4 | small nuclear RNA activating complex, polypeptide 4, 190kDa |
| SPARCL1 | SPARC-like 1 (hevin) |
| SPAST | spastin |
| SPG7 | spastic paraplegia 7 (pure and complicated autosomal recessive) |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| SUN2 | Sad1 and UNC84 domain containing 2 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) |
| TET3 | tet methylcytosine dioxygenase 3 |
| TLE3 | transducin-like enhancer of split 3 |
| TMEM127 | transmembrane protein 127 |
| TMEM161A | transmembrane protein 161A |
| TOX4 | TOX high mobility group box family member 4 |
| TRPV5 | transient receptor potential cation channel, subfamily V, member 5 |
| USF2 | upstream transcription factor 2, c-fos interacting |
| VEGFB | vascular endothelial growth factor B |
| ZFP36L2 | ZFP36 ring finger protein-like 2 |
| ZNF419 | zinc finger protein 419 |
| Symbol | Name |
|---|---|
| A1CF | APOBEC1 complementation factor |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
| ACP6 | acid phosphatase 6, lysophosphatidic |
| ADGRA3 | adhesion G protein-coupled receptor A3 |
| AKIP1 | A kinase (PRKA) interacting protein 1 |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| APEX2 | APEX nuclease (apurinic/apyrimidinic endonuclease) 2 |
| ASAP1-IT1 | ASAP1 intronic transcript 1 |
| BAHD1 | bromo adjacent homology domain containing 1 |
| BATF3 | basic leucine zipper transcription factor, ATF-like 3 |
| BRD9 | bromodomain containing 9 |
| BSG | basigin (Ok blood group) |
| CCDC6 | coiled-coil domain containing 6 |
| CD82 | CD82 molecule |
| CDCP1 | CUB domain containing protein 1 |
| CEP83 | centrosomal protein 83kDa |
| CFAP20 | cilia and flagella associated protein 20 |
| CFL1 | cofilin 1 (non-muscle) |
| CHRNA2 | cholinergic receptor, nicotinic, alpha 2 (neuronal) |
| CHST10 | carbohydrate sulfotransferase 10 |
| CISD1 | CDGSH iron sulfur domain 1 |
| CNNM3 | cyclin and CBS domain divalent metal cation transport mediator 3 |
| COMMD8 | COMM domain containing 8 |
| CPOX | coproporphyrinogen oxidase |
| CTAGE9 | CTAGE family, member 9 |
| CTDNEP1 | CTD nuclear envelope phosphatase 1 |
| DEXI | Dexi homolog (mouse) |
| DMXL1 | Dmx-like 1 |
| DNAAF2 | dynein, axonemal, assembly factor 2 |
| DNAJA4 | DnaJ (Hsp40) homolog, subfamily A, member 4 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 |
| DUSP11 | dual specificity phosphatase 11 (RNA/RNP complex 1-interacting) |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 |
| FAM127A | family with sequence similarity 127, member A |
| FAM179B | family with sequence similarity 179, member B |
| FAM188A | family with sequence similarity 188, member A |
| FAM222B | family with sequence similarity 222, member B |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C |
| GGCT | gamma-glutamylcyclotransferase |
| GJD2 | gap junction protein, delta 2, 36kDa |
| GPATCH2 | G patch domain containing 2 |
| HDHD1 | haloacid dehalogenase-like hydrolase domain containing 1 |
| HOMER1 | homer scaffolding protein 1 |
| IGFLR1 | IGF-like family receptor 1 |
| IGLL3P | immunoglobulin lambda-like polypeptide 3, pseudogene |
| IL24 | interleukin 24 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 |
| ITPKC | inositol-trisphosphate 3-kinase C |
| KATNBL1 | katanin p80 subunit B-like 1 |
| LAS1L | LAS1-like (S. cerevisiae) |
| MBIP | MAP3K12 binding inhibitory protein 1 |
| MOSPD3 | motile sperm domain containing 3 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| NAT9 | N-acetyltransferase 9 (GCN5-related, putative) |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
| NOD1 | nucleotide-binding oligomerization domain containing 1 |
| NOTCH1 | notch 1 |
| PAQR4 | progestin and adipoQ receptor family member IV |
| PELI2 | pellino E3 ubiquitin protein ligase family member 2 |
| PIGA | phosphatidylinositol glycan anchor biosynthesis, class A |
| PIK3R5 | phosphoinositide-3-kinase, regulatory subunit 5 |
| POGK | pogo transposable element with KRAB domain |
| POGLUT1 | protein O-glucosyltransferase 1 |
| POTEKP | POTE ankyrin domain family, member K, pseudogene |
| PPRC1 | peroxisome proliferator-activated receptor gamma, coactivator-related 1 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PRRG1 | proline rich Gla (G-carboxyglutamic acid) 1 |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) |
| PWP2 | PWP2 periodic tryptophan protein homolog (yeast) |
| RBM47 | RNA binding motif protein 47 |
| RFTN1 | raftlin, lipid raft linker 1 |
| SCML1 | sex comb on midleg-like 1 (Drosophila) |
| SDF2L1 | stromal cell-derived factor 2-like 1 |
| SIRT6 | sirtuin 6 |
| SLC2A9 | solute carrier family 2 (facilitated glucose transporter), member 9 |
| SLC36A1 | solute carrier family 36 (proton/amino acid symporter), member 1 |
| SMG9 | SMG9 nonsense mediated mRNA decay factor |
| SNAPC1 | small nuclear RNA activating complex, polypeptide 1, 43kDa |
| SRRD | SRR1 domain containing |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa |
| TCTN2 | tectonic family member 2 |
| TFPT | TCF3 (E2A) fusion partner (in childhood Leukemia) |
| TMEM14A | transmembrane protein 14A |
| TMEM156 | transmembrane protein 156 |
| TMEM160 | transmembrane protein 160 |
| TMEM184C | transmembrane protein 184C |
| TMPRSS6 | transmembrane protease, serine 6 |
| TOMM22 | translocase of outer mitochondrial membrane 22 homolog (yeast) |
| TOPORS | topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase |
| TPCN1 | two pore segment channel 1 |
| TSPYL2 | TSPY-like 2 |
| USP6 | ubiquitin specific peptidase 6 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) |
| WDR5B | WD repeat domain 5B |
| ZCCHC8 | zinc finger, CCHC domain containing 8 |
| ZEB2 | zinc finger E-box binding homeobox 2 |
