hydroquinine-2767 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the hydroquinine-2767 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APBA1 amyloid beta (A4) precursor protein-binding, family A, member 1
ARID1A AT rich interactive domain 1A (SWI-like)
ATP11A ATPase, class VI, type 11A
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BAX BCL2-associated X protein
BBS9 Bardet-Biedl syndrome 9
BCL2A1 BCL2-related protein A1
BTN3A1 butyrophilin, subfamily 3, member A1
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
C11ORF30 chromosome 11 open reading frame 30
CAMK2B calcium/calmodulin-dependent protein kinase II beta
CAMK4 calcium/calmodulin-dependent protein kinase IV
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta
CD58 CD58 molecule
CD84 CD84 molecule
CDC14A cell division cycle 14A
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
COL1A1 collagen, type I, alpha 1
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRTC1 CREB regulated transcription coactivator 1
CYLD cylindromatosis (turban tumor syndrome)
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
DCAF15 DDB1 and CUL4 associated factor 15
DDX28 DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
DSC2 desmocollin 2
DVL3 dishevelled segment polarity protein 3
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
EGFL7 EGF-like-domain, multiple 7
EML2 echinoderm microtubule associated protein like 2
EXT1 exostosin glycosyltransferase 1
FAM46C family with sequence similarity 46, member C
FLJ11292
FRMD8 FERM domain containing 8
FXYD5 FXYD domain containing ion transport regulator 5
GRM2 glutamate receptor, metabotropic 2
GYG2 glycogenin 2
HFE hemochromatosis
HIST1H1D histone cluster 1, H1d
HMOX1 heme oxygenase 1
HN1L hematological and neurological expressed 1-like
HNMT histamine N-methyltransferase
HOMER3 homer scaffolding protein 3
ICOSLG inducible T-cell co-stimulator ligand
IFT140 intraflagellar transport 140
KCNQ2 potassium channel, voltage gated KQT-like subfamily Q, member 2
KLHL25 kelch-like family member 25
LARP4B La ribonucleoprotein domain family, member 4B
MAP4 microtubule-associated protein 4
MAPK14 mitogen-activated protein kinase 14
MARK4 MAP/microtubule affinity-regulating kinase 4
MPL MPL proto-oncogene, thrombopoietin receptor
MRPS18C mitochondrial ribosomal protein S18C
NF1 neurofibromin 1
NME5 NME/NM23 family member 5
NR4A1 nuclear receptor subfamily 4, group A, member 1
PHTF2 putative homeodomain transcription factor 2
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha
PKNOX1 PBX/knotted 1 homeobox 1
PLCH1 phospholipase C, eta 1
PLK4 polo-like kinase 4
PRKCI protein kinase C, iota
PSAT1 phosphoserine aminotransferase 1
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PYY peptide YY
RBMS2 RNA binding motif, single stranded interacting protein 2
RERE arginine-glutamic acid dipeptide (RE) repeats
RPGRIP1 retinitis pigmentosa GTPase regulator interacting protein 1
RPLP2 ribosomal protein, large, P2
RTN2 reticulon 2
RYR1 ryanodine receptor 1 (skeletal)
S100A8 S100 calcium binding protein A8
SAMSN1 SAM domain, SH3 domain and nuclear localization signals 1
SCHIP1 schwannomin interacting protein 1
SH2B1 SH2B adaptor protein 1
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SLCO3A1 solute carrier organic anion transporter family, member 3A1
SOX30 SRY (sex determining region Y)-box 30
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
SYNJ2 synaptojanin 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TDRD3 tudor domain containing 3
TGFBR2 transforming growth factor, beta receptor II (70/80kDa)
TMEM209 transmembrane protein 209
TRIM36 tripartite motif containing 36
TTLL4 tubulin tyrosine ligase-like family member 4
WIPI2 WD repeat domain, phosphoinositide interacting 2
WNT16 wingless-type MMTV integration site family, member 16
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB6 zinc finger and BTB domain containing 6
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF3 zinc finger protein 3
ZNF551 zinc finger protein 551

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ACTL8 actin-like 8
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADCY6 adenylate cyclase 6
AGBL5 ATP/GTP binding protein-like 5
AGPAT3 1-acylglycerol-3-phosphate O-acyltransferase 3
AHDC1 AT hook, DNA binding motif, containing 1
ALAS1 5'-aminolevulinate synthase 1
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
APOO apolipoprotein O
ARMC6 armadillo repeat containing 6
ARMC7 armadillo repeat containing 7
BBC3 BCL2 binding component 3
BCORL1 BCL6 corepressor-like 1
C1ORF159 chromosome 1 open reading frame 159
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
CALCOCO1 calcium binding and coiled-coil domain 1
CBX7 chromobox homolog 7
CCDC85C coiled-coil domain containing 85C
CIDEC cell death-inducing DFFA-like effector c
CLCN2 chloride channel, voltage-sensitive 2
CNR2 cannabinoid receptor 2 (macrophage)
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DIXDC1 DIX domain containing 1
DYRK4 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
FAM155B family with sequence similarity 155, member B
FAM189A2 family with sequence similarity 189, member A2
FCHO1 FCH domain only 1
FCHSD2 FCH and double SH3 domains 2
FGL1 fibrinogen-like 1
GABRB2 gamma-aminobutyric acid (GABA) A receptor, beta 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GPATCH3 G patch domain containing 3
GPR143 G protein-coupled receptor 143
HIST1H2AL histone cluster 1, H2al
HIST1H4D histone cluster 1, H4d
HOXC11 homeobox C11
HTR1E 5-hydroxytryptamine (serotonin) receptor 1E, G protein-coupled
IL22 interleukin 22
INF2 inverted formin, FH2 and WH2 domain containing
KIAA0513 KIAA0513
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein
LZTR1 leucine-zipper-like transcription regulator 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MCMBP minichromosome maintenance complex binding protein
MXD3 MAX dimerization protein 3
MYH9 myosin, heavy chain 9, non-muscle
MYL5 myosin, light chain 5, regulatory
MYO1F myosin IF
N4BP3 NEDD4 binding protein 3
NCSTN nicastrin
OSMR oncostatin M receptor
PACS1 phosphofurin acidic cluster sorting protein 1
PC pyruvate carboxylase
PCDHB3 protocadherin beta 3
PGPEP1 pyroglutamyl-peptidase I
PHC1 polyhomeotic homolog 1 (Drosophila)
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PODXL podocalyxin-like
PODXL2 podocalyxin-like 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
RAB8B RAB8B, member RAS oncogene family
RIBC2 RIB43A domain with coiled-coils 2
SAYSD1 SAYSVFN motif domain containing 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SHARPIN SHANK-associated RH domain interactor
SIDT1 SID1 transmembrane family, member 1
SMG9 SMG9 nonsense mediated mRNA decay factor
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPHK1 sphingosine kinase 1
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STX1A syntaxin 1A (brain)
TESC tescalcin
TFRC transferrin receptor
TMEM120B transmembrane protein 120B
TMEM121 transmembrane protein 121
TMEM132A transmembrane protein 132A
TRAIP TRAF interacting protein
TRPV1 transient receptor potential cation channel, subfamily V, member 1
TSPYL2 TSPY-like 2
TTC23 tetratricopeptide repeat domain 23
TTC31 tetratricopeptide repeat domain 31
TUBA3D tubulin, alpha 3d
TXLNA taxilin alpha
VGF VGF nerve growth factor inducible
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
ZNF34 zinc finger protein 34
ZNF428 zinc finger protein 428
ZNF532 zinc finger protein 532
ZNF768 zinc finger protein 768
ZNF862 zinc finger protein 862
ZSCAN31 zinc finger and SCAN domain containing 31