| Dataset | CMAP Signatures of Differentially Expressed Genes for Small Molecules |
| Category | transcriptomics |
| Type | small molecule perturbation |
| Description | small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis) |
| Similar Terms | |
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197 genes differentially expressed following the hydroquinine-6263 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.
| Symbol | Name |
|---|---|
| ADCY6 | adenylate cyclase 6 |
| AIF1 | allograft inflammatory factor 1 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like |
| AKR1C3 | aldo-keto reductase family 1, member C3 |
| ALS2CL | ALS2 C-terminal like |
| AMT | aminomethyltransferase |
| APP | amyloid beta (A4) precursor protein |
| ARHGAP33 | Rho GTPase activating protein 33 |
| ASPSCR1 | alveolar soft part sarcoma chromosome region, candidate 1 |
| ASTN2 | astrotactin 2 |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| BCL7A | B-cell CLL/lymphoma 7A |
| BMP2K | BMP2 inducible kinase |
| CASP3 | caspase 3, apoptosis-related cysteine peptidase |
| CEP162 | centrosomal protein 162kDa |
| CLN5 | ceroid-lipofuscinosis, neuronal 5 |
| CNNM1 | cyclin and CBS domain divalent metal cation transport mediator 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| CPNE7 | copine VII |
| CTAGE9 | CTAGE family, member 9 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 |
| DCAF17 | DDB1 and CUL4 associated factor 17 |
| DLC1 | DLC1 Rho GTPase activating protein |
| EFNA3 | ephrin-A3 |
| EHMT1 | euchromatic histone-lysine N-methyltransferase 1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| FBXO38 | F-box protein 38 |
| FCER1A | Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide |
| FGF2 | fibroblast growth factor 2 (basic) |
| FGFR3 | fibroblast growth factor receptor 3 |
| FSCN3 | fascin actin-bundling protein 3, testicular |
| GLRX3 | glutaredoxin 3 |
| GNG7 | guanine nucleotide binding protein (G protein), gamma 7 |
| GPC4 | glypican 4 |
| GSTA3 | glutathione S-transferase alpha 3 |
| HMOX1 | heme oxygenase 1 |
| ICA1 | islet cell autoantigen 1, 69kDa |
| IDI2-AS1 | IDI2 antisense RNA 1 |
| IL4R | interleukin 4 receptor |
| INHBA | inhibin, beta A |
| KATNB1 | katanin p80 (WD repeat containing) subunit B 1 |
| KCNF1 | potassium channel, voltage gated modifier subfamily F, member 1 |
| KCNN4 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 |
| KDM4C | lysine (K)-specific demethylase 4C |
| KLF6 | Kruppel-like factor 6 |
| LPIN2 | lipin 2 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B |
| MAP2K2 | mitogen-activated protein kinase kinase 2 |
| MAPK8IP3 | mitogen-activated protein kinase 8 interacting protein 3 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase |
| MMP15 | matrix metallopeptidase 15 (membrane-inserted) |
| MST1 | macrophage stimulating 1 |
| NADK | NAD kinase |
| NEURL1 | neuralized E3 ubiquitin protein ligase 1 |
| NUMA1 | nuclear mitotic apparatus protein 1 |
| NUP214 | nucleoporin 214kDa |
| PCNX | pecanex homolog (Drosophila) |
| PDK2 | pyruvate dehydrogenase kinase, isozyme 2 |
| PDLIM7 | PDZ and LIM domain 7 (enigma) |
| PGPEP1 | pyroglutamyl-peptidase I |
| PIP5K1C | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma |
| PLSCR3 | phospholipid scramblase 3 |
| PLXNA1 | plexin A1 |
| POFUT1 | protein O-fucosyltransferase 1 |
| PPP1R2P9 | protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9 |
| PPP5C | protein phosphatase 5, catalytic subunit |
| PPT2 | palmitoyl-protein thioesterase 2 |
| PRKACA | protein kinase, cAMP-dependent, catalytic, alpha |
| PRR5 | proline rich 5 (renal) |
| PSD4 | pleckstrin and Sec7 domain containing 4 |
| PTGS1 | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| PTRF | polymerase I and transcript release factor |
| RASAL2 | RAS protein activator like 2 |
| RCAN1 | regulator of calcineurin 1 |
| RIN2 | Ras and Rab interactor 2 |
| RNF19B | ring finger protein 19B |
| SCAMP4 | secretory carrier membrane protein 4 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa |
| SIX3 | SIX homeobox 3 |
| SLC12A8 | solute carrier family 12, member 8 |
| SNAPC2 | small nuclear RNA activating complex, polypeptide 2, 45kDa |
| SOX12 | SRY (sex determining region Y)-box 12 |
| SP1 | Sp1 transcription factor |
| SPPL2B | signal peptide peptidase like 2B |
| SRCAP | Snf2-related CREBBP activator protein |
| SUGP1 | SURP and G patch domain containing 1 |
| SYBU | syntabulin (syntaxin-interacting) |
| TMEM222 | transmembrane protein 222 |
| TRIP10 | thyroid hormone receptor interactor 10 |
| TUBGCP4 | tubulin, gamma complex associated protein 4 |
| USP48 | ubiquitin specific peptidase 48 |
| VIPR1 | vasoactive intestinal peptide receptor 1 |
| VIPR2 | vasoactive intestinal peptide receptor 2 |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDR55 | WD repeat domain 55 |
| WDR62 | WD repeat domain 62 |
| ZAK | sterile alpha motif and leucine zipper containing kinase AZK |
| ZNF282 | zinc finger protein 282 |
| Symbol | Name |
|---|---|
| ABCF3 | ATP-binding cassette, sub-family F (GCN20), member 3 |
| AES | amino-terminal enhancer of split |
| ALAS1 | 5'-aminolevulinate synthase 1 |
| ARHGEF5 | Rho guanine nucleotide exchange factor (GEF) 5 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BBC3 | BCL2 binding component 3 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) |
| BIK | BCL2-interacting killer (apoptosis-inducing) |
| C1ORF35 | chromosome 1 open reading frame 35 |
| C4ORF29 | chromosome 4 open reading frame 29 |
| CA11 | carbonic anhydrase XI |
| CALCOCO1 | calcium binding and coiled-coil domain 1 |
| CAPN15 | calpain 15 |
| CBX4 | chromobox homolog 4 |
| CDADC1 | cytidine and dCMP deaminase domain containing 1 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 |
| CPPED1 | calcineurin-like phosphoesterase domain containing 1 |
| ENTPD5 | ectonucleoside triphosphate diphosphohydrolase 5 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM131A | family with sequence similarity 131, member A |
| FAM53B | family with sequence similarity 53, member B |
| FKBP10 | FK506 binding protein 10, 65 kDa |
| FKBP14 | FK506 binding protein 14, 22 kDa |
| FLT4 | fms-related tyrosine kinase 4 |
| FOXRED2 | FAD-dependent oxidoreductase domain containing 2 |
| GALT | galactose-1-phosphate uridylyltransferase |
| GINS4 | GINS complex subunit 4 (Sld5 homolog) |
| GLTSCR1 | glioma tumor suppressor candidate region gene 1 |
| GNG4 | guanine nucleotide binding protein (G protein), gamma 4 |
| GRAMD4 | GRAM domain containing 4 |
| GRB7 | growth factor receptor-bound protein 7 |
| GSTM2 | glutathione S-transferase mu 2 (muscle) |
| GTF2I | general transcription factor IIi |
| HIRA | histone cell cycle regulator |
| HIST2H2AA3 | histone cluster 2, H2aa3 |
| KCNK15 | potassium channel, two pore domain subfamily K, member 15 |
| KCNMB3 | potassium channel subfamily M regulatory beta subunit 3 |
| KIAA0894 | KIAA0894 protein |
| KIFC1 | kinesin family member C1 |
| LRRC20 | leucine rich repeat containing 20 |
| LYPLA2P1 | lysophospholipase II pseudogene 1 |
| MCC | mutated in colorectal cancers |
| MED15 | mediator complex subunit 15 |
| MOCS3 | molybdenum cofactor synthesis 3 |
| MUL1 | mitochondrial E3 ubiquitin protein ligase 1 |
| NDRG1 | N-myc downstream regulated 1 |
| NDRG4 | NDRG family member 4 |
| NMRK1 | nicotinamide riboside kinase 1 |
| NUDT13 | nudix (nucleoside diphosphate linked moiety X)-type motif 13 |
| OR7E47P | olfactory receptor, family 7, subfamily E, member 47 pseudogene |
| PACS1 | phosphofurin acidic cluster sorting protein 1 |
| PADI1 | peptidyl arginine deiminase, type I |
| PAIP2B | poly(A) binding protein interacting protein 2B |
| PAQR3 | progestin and adipoQ receptor family member III |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 |
| PCSK7 | proprotein convertase subtilisin/kexin type 7 |
| PDE12 | phosphodiesterase 12 |
| PDIA3 | protein disulfide isomerase family A, member 3 |
| PDK1 | pyruvate dehydrogenase kinase, isozyme 1 |
| PGGT1B | protein geranylgeranyltransferase type I, beta subunit |
| PIM2 | Pim-2 proto-oncogene, serine/threonine kinase |
| PLD3 | phospholipase D family, member 3 |
| PMCH | pro-melanin-concentrating hormone |
| POMT2 | protein-O-mannosyltransferase 2 |
| PPP1R3C | protein phosphatase 1, regulatory subunit 3C |
| PRRG4 | proline rich Gla (G-carboxyglutamic acid) 4 (transmembrane) |
| RAB3IL1 | RAB3A interacting protein (rabin3)-like 1 |
| RGS19 | regulator of G-protein signaling 19 |
| RNF39 | ring finger protein 39 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) |
| RPL13P5 | ribosomal protein L13 pseudogene 5 |
| RPL23AP7 | ribosomal protein L23a pseudogene 7 |
| RSPH14 | radial spoke head 14 homolog (Chlamydomonas) |
| SDF2 | stromal cell-derived factor 2 |
| SLC17A5 | solute carrier family 17 (acidic sugar transporter), member 5 |
| SUZ12P1 | suppressor of zeste 12 homolog pseudogene 1 |
| TCTN1 | tectonic family member 1 |
| TFRC | transferrin receptor |
| THNSL1 | threonine synthase-like 1 (S. cerevisiae) |
| TIMM50 | translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae) |
| TMEM104 | transmembrane protein 104 |
| TMUB2 | transmembrane and ubiquitin-like domain containing 2 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 |
| TRAF2 | TNF receptor-associated factor 2 |
| TRPC5 | transient receptor potential cation channel, subfamily C, member 5 |
| TSPAN1 | tetraspanin 1 |
| TUT1 | terminal uridylyl transferase 1, U6 snRNA-specific |
| UNC119 | unc-119 homolog (C. elegans) |
| USP36 | ubiquitin specific peptidase 36 |
| WDR76 | WD repeat domain 76 |
| XK | X-linked Kx blood group |
| ZDHHC14 | zinc finger, DHHC-type containing 14 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF141 | zinc finger protein 141 |
| ZNF442 | zinc finger protein 442 |
| ZNF768 | zinc finger protein 768 |
