hydroxyachillin-2812 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the hydroxyachillin-2812 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AEBP1 AE binding protein 1
AGER advanced glycosylation end product-specific receptor
AGO4 argonaute RISC catalytic component 4
AKAP7 A kinase (PRKA) anchor protein 7
APOBEC1 apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
C3AR1 complement component 3a receptor 1
CABIN1 calcineurin binding protein 1
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACTIN cactin, spliceosome C complex subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP4 caspase 4, apoptosis-related cysteine peptidase
CD1A CD1a molecule
CD79B CD79b molecule, immunoglobulin-associated beta
CD82 CD82 molecule
CD8A CD8a molecule
CNN1 calponin 1, basic, smooth muscle
CPB1 carboxypeptidase B1 (tissue)
CSF2RB colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
CSPG4 chondroitin sulfate proteoglycan 4
DFNB31 deafness, autosomal recessive 31
DMTN dematin actin binding protein
DOHH deoxyhypusine hydroxylase/monooxygenase
EDAR ectodysplasin A receptor
FAM76A family with sequence similarity 76, member A
FASLG Fas ligand (TNF superfamily, member 6)
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
GCNT2 glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
HAP1 huntingtin-associated protein 1
HCFC1 host cell factor C1
HES2 hes family bHLH transcription factor 2
HLA-DOA major histocompatibility complex, class II, DO alpha
HLA-DPA1 major histocompatibility complex, class II, DP alpha 1
HN1L hematological and neurological expressed 1-like
HNRNPA3P1 heterogeneous nuclear ribonucleoprotein A3 pseudogene 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSF2BP heat shock transcription factor 2 binding protein
IGHM immunoglobulin heavy constant mu
IL19 interleukin 19
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
INHA inhibin, alpha
IRF8 interferon regulatory factor 8
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
KRT19P2 keratin 19 pseudogene 2
LHX1 LIM homeobox 1
MAL mal, T-cell differentiation protein
MAPK8 mitogen-activated protein kinase 8
MEGF6 multiple EGF-like-domains 6
MMP25 matrix metallopeptidase 25
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYH7 myosin, heavy chain 7, cardiac muscle, beta
MYO15B myosin XVB
NOP14-AS1 NOP14 antisense RNA 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
OCLM oculomedin
PDCD2 programmed cell death 2
PILRA paired immunoglobin-like type 2 receptor alpha
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid)
PML promyelocytic leukemia
POFUT1 protein O-fucosyltransferase 1
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
RFX2 regulatory factor X, 2 (influences HLA class II expression)
ROM1 retinal outer segment membrane protein 1
RUNX1 runt-related transcription factor 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINA7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
SGK2 serum/glucocorticoid regulated kinase 2
SH2D3A SH2 domain containing 3A
SIRT4 sirtuin 4
SLC35E2 solute carrier family 35, member E2
SLC48A1 solute carrier family 48 (heme transporter), member 1
SLC7A9 solute carrier family 7 (amino acid transporter light chain, bo,+ system), member 9
SLCO2A1 solute carrier organic anion transporter family, member 2A1
SPN sialophorin
STAB1 stabilin 1
STARD8 StAR-related lipid transfer (START) domain containing 8
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYT5 synaptotagmin V
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBX10 T-box 10
TBX5 T-box 5
TICAM1 toll-like receptor adaptor molecule 1
TM4SF4 transmembrane 4 L six family member 4
TMEM63A transmembrane protein 63A
TNFRSF8 tumor necrosis factor receptor superfamily, member 8
TNNT2 troponin T type 2 (cardiac)
TRAPPC9 trafficking protein particle complex 9
TRD T cell receptor delta locus
TRIB2 tribbles pseudokinase 2
TTLL4 tubulin tyrosine ligase-like family member 4
VAC14 Vac14 homolog (S. cerevisiae)
ZNF646 zinc finger protein 646
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
ANXA1 annexin A1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATP11B ATPase, class VI, type 11B
C17ORF75 chromosome 17 open reading frame 75
C1ORF109 chromosome 1 open reading frame 109
C1ORF159 chromosome 1 open reading frame 159
CAMK1 calcium/calmodulin-dependent protein kinase I
CD302 CD302 molecule
CD81 CD81 molecule
CENPC centromere protein C
CHKB choline kinase beta
CLEC16A C-type lectin domain family 16, member A
CPOX coproporphyrinogen oxidase
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEAF1 DEAF1 transcription factor
DENND4A DENN/MADD domain containing 4A
DNMT3A DNA (cytosine-5-)-methyltransferase 3 alpha
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ETAA1 Ewing tumor-associated antigen 1
EYA2 EYA transcriptional coactivator and phosphatase 2
FAM188A family with sequence similarity 188, member A
GAMT guanidinoacetate N-methyltransferase
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GLTSCR1 glioma tumor suppressor candidate region gene 1
GPRC5C G protein-coupled receptor, class C, group 5, member C
GRB2 growth factor receptor-bound protein 2
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
H2AFJ H2A histone family, member J
HIRA histone cell cycle regulator
HOOK1 hook microtubule-tethering protein 1
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
IP6K1 inositol hexakisphosphate kinase 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KIAA0125 KIAA0125
KIAA1551 KIAA1551
LINS lines homolog (Drosophila)
LRIF1 ligand dependent nuclear receptor interacting factor 1
LRRC8E leucine rich repeat containing 8 family, member E
MBTD1 mbt domain containing 1
MGC12488
MITF microphthalmia-associated transcription factor
MTM1 myotubularin 1
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NIPAL2 NIPA-like domain containing 2
NPY1R neuropeptide Y receptor Y1
NRBF2 nuclear receptor binding factor 2
OXR1 oxidation resistance 1
PARP16 poly (ADP-ribose) polymerase family, member 16
PARP4 poly (ADP-ribose) polymerase family, member 4
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PLA2G12A phospholipase A2, group XIIA
PLD3 phospholipase D family, member 3
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMP22 peripheral myelin protein 22
POLR2J2 polymerase (RNA) II (DNA directed) polypeptide J2
PPIP5K2 diphosphoinositol pentakisphosphate kinase 2
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTBP2 polypyrimidine tract binding protein 2
PTPRE protein tyrosine phosphatase, receptor type, E
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RAB33B RAB33B, member RAS oncogene family
RAD54L RAD54-like (S. cerevisiae)
RBM41 RNA binding motif protein 41
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
SCRIB scribbled planar cell polarity protein
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8
SMAD7 SMAD family member 7
SOWAHC sosondowah ankyrin repeat domain family member C
STXBP3 syntaxin binding protein 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYNGR3 synaptogyrin 3
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TMEM135 transmembrane protein 135
TMEM62 transmembrane protein 62
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TNS3 tensin 3
TPST2 tyrosylprotein sulfotransferase 2
TPTE transmembrane phosphatase with tensin homology
TRAIP TRAF interacting protein
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
VASH2 vasohibin 2
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
YTHDF3 YTH N(6)-methyladenosine RNA binding protein 3
ZBTB3 zinc finger and BTB domain containing 3
ZBTB6 zinc finger and BTB domain containing 6
ZHX2 zinc fingers and homeoboxes 2
ZNF143 zinc finger protein 143
ZNF227 zinc finger protein 227
ZNF408 zinc finger protein 408
ZNF768 zinc finger protein 768
ZNF813 zinc finger protein 813
ZW10 zw10 kinetochore protein