hydroxyachillin-4213 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the hydroxyachillin-4213 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACOT11 acyl-CoA thioesterase 11
ACSBG1 acyl-CoA synthetase bubblegum family member 1
ACSL5 acyl-CoA synthetase long-chain family member 5
ADAM28 ADAM metallopeptidase domain 28
ADGRG1 adhesion G protein-coupled receptor G1
ANGPT4 angiopoietin 4
ANKRD7 ankyrin repeat domain 7
APC adenomatous polyposis coli
ATF7IP activating transcription factor 7 interacting protein
ATP1A3 ATPase, Na+/K+ transporting, alpha 3 polypeptide
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BIN1 bridging integrator 1
BST1 bone marrow stromal cell antigen 1
C11ORF63 chromosome 11 open reading frame 63
C14ORF79 chromosome 14 open reading frame 79
C4BPA complement component 4 binding protein, alpha
C8ORF44 chromosome 8 open reading frame 44
CCL2 chemokine (C-C motif) ligand 2
CDK13 cyclin-dependent kinase 13
CEL carboxyl ester lipase
CHRNA10 cholinergic receptor, nicotinic, alpha 10 (neuronal)
CLCN7 chloride channel, voltage-sensitive 7
CLSTN3 calsyntenin 3
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene
CNOT3 CCR4-NOT transcription complex, subunit 3
CREBZF CREB/ATF bZIP transcription factor
CST4 cystatin S
CTNNA3 catenin (cadherin-associated protein), alpha 3
DAPK2 death-associated protein kinase 2
DKK3 dickkopf WNT signaling pathway inhibitor 3
DLX2 distal-less homeobox 2
DLX5 distal-less homeobox 5
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DOK4 docking protein 4
EFNB3 ephrin-B3
FAM135A family with sequence similarity 135, member A
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLT1 fms-related tyrosine kinase 1
FRMD4B FERM domain containing 4B
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GPR45 G protein-coupled receptor 45
GSDMB gasdermin B
HDAC11 histone deacetylase 11
HIC2 hypermethylated in cancer 2
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
HOMER3 homer scaffolding protein 3
IFITM1 interferon induced transmembrane protein 1
IKZF1 IKAROS family zinc finger 1 (Ikaros)
IL2RG interleukin 2 receptor, gamma
IQCK IQ motif containing K
ITGA4 integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
KIF21B kinesin family member 21B
KLF12 Kruppel-like factor 12
LEPR leptin receptor
LRP1 low density lipoprotein receptor-related protein 1
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MKRN3 makorin ring finger protein 3
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MTRF1L mitochondrial translational release factor 1-like
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NOL12 nucleolar protein 12
NR2F6 nuclear receptor subfamily 2, group F, member 6
OSBPL10 oxysterol binding protein-like 10
OVOL2 ovo-like zinc finger 2
PBRM1 polybromo 1
PDLIM5 PDZ and LIM domain 5
PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
PKNOX2 PBX/knotted 1 homeobox 2
PTPRH protein tyrosine phosphatase, receptor type, H
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRR protein tyrosine phosphatase, receptor type, R
PVT1 Pvt1 oncogene (non-protein coding)
RAB33A RAB33A, member RAS oncogene family
SAA3P serum amyloid A3 pseudogene
SATB2 SATB homeobox 2
SBNO1 strawberry notch homolog 1 (Drosophila)
SCARB1 scavenger receptor class B, member 1
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3
SEZ6L seizure related 6 homolog (mouse)-like
SGSM2 small G protein signaling modulator 2
SHMT1 serine hydroxymethyltransferase 1 (soluble)
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SMG6 SMG6 nonsense mediated mRNA decay factor
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SSX5 synovial sarcoma, X breakpoint 5
STON1 stonin 1
SUGP1 SURP and G patch domain containing 1
TAOK1 TAO kinase 1
TNS1 tensin 1
TTYH1 tweety family member 1
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
ULK4 unc-51 like kinase 4
UPK1B uroplakin 1B
VN1R1 vomeronasal 1 receptor 1
XCR1 chemokine (C motif) receptor 1

decreased expression

Symbol Name
ACTG2 actin, gamma 2, smooth muscle, enteric
ADCY6 adenylate cyclase 6
AGBL3 ATP/GTP binding protein-like 3
AKR1C4 aldo-keto reductase family 1, member C4
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
BTF3P11 basic transcription factor 3 pseudogene 11
CAMKMT calmodulin-lysine N-methyltransferase
CAPN5 calpain 5
CDK9 cyclin-dependent kinase 9
CDKL3 cyclin-dependent kinase-like 3
CINP cyclin-dependent kinase 2 interacting protein
CLDN1 claudin 1
CLEC16A C-type lectin domain family 16, member A
CNR2 cannabinoid receptor 2 (macrophage)
CORO1A coronin, actin binding protein, 1A
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DNAH17 dynein, axonemal, heavy chain 17
DUSP9 dual specificity phosphatase 9
ERCC4 excision repair cross-complementation group 4
FAM110B family with sequence similarity 110, member B
FLJ21369 uncharacterized protein FLJ21369
FRS3 fibroblast growth factor receptor substrate 3
GALK1 galactokinase 1
GMPR guanosine monophosphate reductase
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GRM4 glutamate receptor, metabotropic 4
GSTA3 glutathione S-transferase alpha 3
GSTCD glutathione S-transferase, C-terminal domain containing
HIST1H2AK histone cluster 1, H2ak
HIST1H2BN histone cluster 1, H2bn
IFIT3 interferon-induced protein with tetratricopeptide repeats 3
IFT140 intraflagellar transport 140
IL12RB1 interleukin 12 receptor, beta 1
IL17RB interleukin 17 receptor B
IL6 interleukin 6
ITK IL2-inducible T-cell kinase
KANSL3 KAT8 regulatory NSL complex subunit 3
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KDM8 lysine (K)-specific demethylase 8
KIAA0319L KIAA0319-like
KPNA5 karyopherin alpha 5 (importin alpha 6)
LIME1 Lck interacting transmembrane adaptor 1
LMTK1 lemur tail kinase 1
LOC100287590 uncharacterized LOC100287590
LOC157562 uncharacterized LOC157562
LTC4S leukotriene C4 synthase
MAGEA6 melanoma antigen family A6
MOCS3 molybdenum cofactor synthesis 3
MPI mannose phosphate isomerase
MRPL41 mitochondrial ribosomal protein L41
MXRA8 matrix-remodelling associated 8
NBEAL2 neurobeachin-like 2
NOL10 nucleolar protein 10
NR1H3 nuclear receptor subfamily 1, group H, member 3
NSUN6 NOP2/Sun domain family, member 6
NTSR1 neurotensin receptor 1 (high affinity)
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OTOF otoferlin
PACSIN3 protein kinase C and casein kinase substrate in neurons 3
PBOV1 prostate and breast cancer overexpressed 1
PLAG1 pleiomorphic adenoma gene 1
PLBD1 phospholipase B domain containing 1
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
POMT2 protein-O-mannosyltransferase 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PROX1 prospero homeobox 1
PRR7 proline rich 7 (synaptic)
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RAPSN receptor-associated protein of the synapse
RBM12B-AS1 RBM12B antisense RNA 1
RGS17 regulator of G-protein signaling 17
RIMBP2 RIMS binding protein 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPP25 ribonuclease P/MRP 25kDa subunit
RWDD2A RWD domain containing 2A
S1PR1 sphingosine-1-phosphate receptor 1
SCG2 secretogranin II
SLC9A3 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3
SPATA1 spermatogenesis associated 1
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TBC1D8B TBC1 domain family, member 8B (with GRAM domain)
TIMP4 TIMP metallopeptidase inhibitor 4
TM7SF2 transmembrane 7 superfamily member 2
TMC5 transmembrane channel-like 5
TMEM53 transmembrane protein 53
TMPRSS4 transmembrane protease, serine 4
TPRA1 transmembrane protein, adipocyte asscociated 1
TTLL1 tubulin tyrosine ligase-like family member 1
VASH1 vasohibin 1
XAB2 XPA binding protein 2
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZNF225 zinc finger protein 225
ZNF816 zinc finger protein 816
ZSCAN2 zinc finger and SCAN domain containing 2