hydroxyachillin-4797 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the hydroxyachillin-4797 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ACSBG2 acyl-CoA synthetase bubblegum family member 2
ACTL8 actin-like 8
AIM1L absent in melanoma 1-like
ARHGEF17 Rho guanine nucleotide exchange factor (GEF) 17
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
BGN biglycan
BRINP2 bone morphogenetic protein/retinoic acid inducible neural-specific 2
C14ORF105 chromosome 14 open reading frame 105
C2ORF27A chromosome 2 open reading frame 27A
CADM3 cell adhesion molecule 3
CALD1 caldesmon 1
CCDC71 coiled-coil domain containing 71
CDK10 cyclin-dependent kinase 10
CFP complement factor properdin
CHAT choline O-acetyltransferase
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CIDEB cell death-inducing DFFA-like effector b
CLDN17 claudin 17
CNKSR2 connector enhancer of kinase suppressor of Ras 2
COL9A3 collagen, type IX, alpha 3
COMMD4 COMM domain containing 4
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CXCR2 chemokine (C-X-C motif) receptor 2
DGCR8 DGCR8 microprocessor complex subunit
DIEXF digestive organ expansion factor homolog (zebrafish)
DTNA dystrobrevin, alpha
EPOR erythropoietin receptor
ERN1 endoplasmic reticulum to nucleus signaling 1
FOSL2 FOS-like antigen 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLDC glycine dehydrogenase (decarboxylating)
GPR143 G protein-coupled receptor 143
GSN gelsolin
HCFC1 host cell factor C1
HCG4 HLA complex group 4 (non-protein coding)
HOXA4 homeobox A4
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD)
ICOSLG inducible T-cell co-stimulator ligand
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
LRRN3 leucine rich repeat neuronal 3
LY6G6C lymphocyte antigen 6 complex, locus G6C
MAN1C1 mannosidase, alpha, class 1C, member 1
MBD2 methyl-CpG binding domain protein 2
MCM3AP minichromosome maintenance complex component 3 associated protein
MCOLN3 mucolipin 3
MMP25 matrix metallopeptidase 25
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDOR1 NADPH dependent diflavin oxidoreductase 1
NOL10 nucleolar protein 10
NPTX1 neuronal pentraxin I
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
OGFR opioid growth factor receptor
OLFML2A olfactomedin-like 2A
PALM paralemmin
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble)
PIDD1 p53-induced death domain protein 1
PITX1 paired-like homeodomain 1
PLAC4 placenta-specific 4
PLCE1 phospholipase C, epsilon 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHH3 pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
POFUT1 protein O-fucosyltransferase 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
RAB2A RAB2A, member RAS oncogene family
RAI2 retinoic acid induced 2
RS1 retinoschisin 1
RUNX1 runt-related transcription factor 1
S100A8 S100 calcium binding protein A8
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SERHL2 serine hydrolase-like 2
SFTPB surfactant protein B
SHOX2 short stature homeobox 2
SIGLEC8 sialic acid binding Ig-like lectin 8
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1)
SOX15 SRY (sex determining region Y)-box 15
SPRR2B small proline-rich protein 2B
STX7 syntaxin 7
SYK spleen tyrosine kinase
TCF3 transcription factor 3
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
THBS3 thrombospondin 3
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TMEM63A transmembrane protein 63A
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAF3IP3 TRAF3 interacting protein 3
TTLL7 tubulin tyrosine ligase-like family member 7
VAV2 vav 2 guanine nucleotide exchange factor
WDTC1 WD and tetratricopeptide repeats 1
WWOX WW domain containing oxidoreductase
XAF1 XIAP associated factor 1
ZER1 zyg-11 related, cell cycle regulator
ZNF10 zinc finger protein 10
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ADCY6 adenylate cyclase 6
ALPK1 alpha-kinase 1
ANKEF1 ankyrin repeat and EF-hand domain containing 1
ANXA1 annexin A1
ARNTL2 aryl hydrocarbon receptor nuclear translocator-like 2
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ASPHD1 aspartate beta-hydroxylase domain containing 1
AUTS2 autism susceptibility candidate 2
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
B9D2 B9 protein domain 2
BCOR BCL6 corepressor
C11ORF80 chromosome 11 open reading frame 80
C2ORF54 chromosome 2 open reading frame 54
CAMKMT calmodulin-lysine N-methyltransferase
CCNO cyclin O
CEP70 centrosomal protein 70kDa
CHMP7 charged multivesicular body protein 7
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CNGB3 cyclic nucleotide gated channel beta 3
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
DUSP2 dual specificity phosphatase 2
DZANK1 double zinc ribbon and ankyrin repeat domains 1
EDEM1 ER degradation enhancer, mannosidase alpha-like 1
EPB41L5 erythrocyte membrane protein band 4.1 like 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM120C family with sequence similarity 120C
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP1B FK506 binding protein 1B, 12.6 kDa
FURIN furin (paired basic amino acid cleaving enzyme)
FZD3 frizzled class receptor 3
GINS4 GINS complex subunit 4 (Sld5 homolog)
GJA1 gap junction protein, alpha 1, 43kDa
GPR87 G protein-coupled receptor 87
GTF3C5 general transcription factor IIIC, polypeptide 5, 63kDa
HIST1H2AL histone cluster 1, H2al
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IQSEC2 IQ motif and Sec7 domain 2
IREB2 iron-responsive element binding protein 2
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KCTD17 potassium channel tetramerization domain containing 17
LCP1 lymphocyte cytosolic protein 1 (L-plastin)
LHX1 LIM homeobox 1
LINS lines homolog (Drosophila)
LMCD1 LIM and cysteine-rich domains 1
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRRC8E leucine rich repeat containing 8 family, member E
MAN2C1 mannosidase, alpha, class 2C, member 1
MANBA mannosidase, beta A, lysosomal
MANEA mannosidase, endo-alpha
MC1R melanocortin 1 receptor (alpha melanocyte stimulating hormone receptor)
MRPS18C mitochondrial ribosomal protein S18C
NCAM2 neural cell adhesion molecule 2
NUPL2 nucleoporin like 2
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PARD6A par-6 family cell polarity regulator alpha
PARP12 poly (ADP-ribose) polymerase family, member 12
PCDHB3 protocadherin beta 3
PELI1 pellino E3 ubiquitin protein ligase 1
PHC1 polyhomeotic homolog 1 (Drosophila)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD2 phospholipase D2
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLH polymerase (DNA directed), eta
PTDSS2 phosphatidylserine synthase 2
RGS17 regulator of G-protein signaling 17
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
SAMD9 sterile alpha motif domain containing 9
SAYSD1 SAYSVFN motif domain containing 1
SCAI suppressor of cancer cell invasion
SDC3 syndecan 3
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC12A9 solute carrier family 12, member 9
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SNX16 sorting nexin 16
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TAOK1 TAO kinase 1
TESK2 testis-specific kinase 2
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM184C transmembrane protein 184C
TMEM45A transmembrane protein 45A
TRAIP TRAF interacting protein
TRAPPC13 trafficking protein particle complex 13
TRIM25 tripartite motif containing 25
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF254 zinc finger protein 254
ZNF611 zinc finger protein 611
ZNF696 zinc finger protein 696
ZNF767P zinc finger family member 767, pseudogene
ZNF787 zinc finger protein 787
ZNHIT2 zinc finger, HIT-type containing 2