| Dataset | GO Molecular Function Annotations 2025 |
| Category | structural or functional annotations |
| Type | molecular function |
| Description | Catalysis of the reaction: (S)-3-hydroxy-3-methylglutaryl-CoA = acetoacetate + acetyl-CoA. (Gene Ontology, GO_0004419) |
| External Link | http://amigo.geneontology.org/amigo/term/GO:0004419 |
| Similar Terms | |
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2 genes performing the hydroxymethylglutaryl-CoA lyase activity molecular function from the curated GO Molecular Function Annotations 2025 dataset.